Tirilomis, Theodor

[["dc.bibliographiccitation.firstpage","E40"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Artificial Organs"],["dc.bibliographiccitation.lastpage","E43"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Malliarou, Stella"],["dc.contributor.author","Bensch, Marc"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T09:30:27Z"],["dc.date.available","2018-11-07T09:30:27Z"],["dc.date.issued","2013"],["dc.description.abstract","Although the mechanisms of neurological disorders after cardiac surgery in neonates are still not fully understood, alterations in blood flow after cardiopulmonary bypass (CPB) may lead to cerebral injury. The aim of the study was the analysis of flow changes in the carotid artery of neonatal piglets after CPB. Ten neonatal piglets (younger than 7 days) were connected to the CPB and further management underwent three steps: (i) cooling to 32 degrees C core temperature within 30?min; (ii) cardiac arrest under cardioplegic myocardial protection for 90?min; and (iii) rewarming to 37 degrees C after cross-clamp release (60?min of reperfusion). In summary, piglets were separated from CPB after a total duration time of 180?min. The blood flow was measured in the left carotid artery by an ultrasonic flow probe before CPB (baseline), immediately after CPB, 30?min, and 60?min after CPB. Additionally, the pulsatility index and the resistance index were calculated and compared. Finally, the relation of the carotid artery flow data with the corresponding pressure data at each time point was compared. After termination of CPB, the carotid artery mean flow was reduced from 28.34?+/-?13.79?mL/min at baseline to 20.91?+/-?10.61?mL/min and remained reduced 30 and 60?min after CPB termination (19.71?+/-?11.11 and 17.64?+/-?15.31?mL/min, respectively). Both the pulsatility and the resistance index were reduced immediately after CPB termination and increased thereafter. Nevertheless, values did not reach statistical significance. In conclusion, the carotid Doppler flow immediately after CPB and mild hypothermia in neonatal piglets was lower than before CPB due to reduced vascular resistance. Additionally, the pressureflow relation revealed that immediately after CPB, a higher pressure is required to obtain adequate flow."],["dc.identifier.doi","10.1111/aor.12012"],["dc.identifier.isi","000313706400013"],["dc.identifier.pmid","23305586"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31309"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","8th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion"],["dc.relation.eventlocation","Istanbul, TURKEY"],["dc.relation.issn","1525-1594"],["dc.relation.issn","0160-564X"],["dc.title","Carotid Doppler Flow After Cardiopulmonary Bypass and Mild Hypothermia in Neonatal Piglets"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","380"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","The Medical Journal of Australia"],["dc.bibliographiccitation.lastpage","380"],["dc.bibliographiccitation.volume","178"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Malliarou, Stella"],["dc.date.accessioned","2021-06-01T10:48:58Z"],["dc.date.available","2021-06-01T10:48:58Z"],["dc.date.issued","2003"],["dc.format.extent","380"],["dc.identifier.doi","10.5694/j.1326-5377.2003.tb05254.x"],["dc.identifier.isi","000183188300007"],["dc.identifier.pmid","12776719"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86119"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Australasian Med Publ Co Ltd"],["dc.relation.eissn","1326-5377"],["dc.relation.issn","0025-729X"],["dc.title","Medical history and the European Union: Papanicolaou and Asklepios"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","91"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Artificial Organs"],["dc.bibliographiccitation.lastpage","95"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Malliarou, Stella"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T09:46:51Z"],["dc.date.available","2018-11-07T09:46:51Z"],["dc.date.issued","2014"],["dc.description.abstract","The mechanisms of cerebral injury after cardiac surgery in neonates are not clear. The aim of the study was the analysis of flow changes in the carotid artery of neonatal piglets after deep hypothermic circulatory arrest (DHCA). Eight neonatal piglets were connected to cardiopulmonary bypass (CPB) and underwent (i) cooling to 18 C core temperature within 30 min, (ii) DHCA for 90 min, and finally (iii) rewarming to 37 degrees C after cross-clamp release (60 min of reperfusion). The blood flow was measured in the left carotid artery by an ultrasonic flow probe before CPB (baseline; T-0), immediately after termination of reperfusion on CPB (T-1), 30 min later (T-2), and 60 min later (T-3). Additionally, the pulsatility index and the resistance index were calculated and compared. Finally, the relationship between the carotid artery flow and the corresponding pressure at each time-point was compared. After termination of CPB (T-1), the mean carotid artery flow was reduced from 45.26 +/- 2.58 mL/min at baseline to 23.29 +/- 2.58 mL/min (P < 0.001) and remained reduced 30 and 60 min later (P < 0.001 vs. baseline). Both the pulsatility index and the resistance index were increased after termination of reperfusion, with the maximum occurring 30 min after CPB end. In conclusion, the carotid artery Doppler flow in neonatal piglets was reduced after DHCA, while the indices of pulsatility and resistance increased."],["dc.identifier.doi","10.1111/aor.12214"],["dc.identifier.isi","000329288500015"],["dc.identifier.pmid","24206193"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34980"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","9th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion"],["dc.relation.eventlocation","Hershey, PA"],["dc.relation.issn","1525-1594"],["dc.relation.issn","0160-564X"],["dc.title","Carotid Artery Doppler Flow Pattern After Deep Hypothermic Circulatory Arrest in Neonatal Piglets"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]