Zenker, Dieter

[["dc.bibliographiccitation.firstpage","93A"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of the American College of Cardiology"],["dc.bibliographiccitation.lastpage","94A"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Moeller, K."],["dc.contributor.author","Stevens, J."],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Kuehn, R."],["dc.contributor.author","Unterberg, Christina"],["dc.date.accessioned","2018-11-07T10:31:11Z"],["dc.date.available","2018-11-07T10:31:11Z"],["dc.date.issued","2002"],["dc.identifier.isi","000174106700404"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44044"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.publisher.place","New york"],["dc.relation.issn","0735-1097"],["dc.title","Subthreshold test pulse versus shock delivery to evaluate high voltage impedance in ICD patients"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1577"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Pacing and Clinical Electrophysiology"],["dc.bibliographiccitation.lastpage","1582"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Stevens, J."],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Krieglstein, H."],["dc.contributor.author","Unterberg, Christina"],["dc.date.accessioned","2018-11-07T09:54:05Z"],["dc.date.available","2018-11-07T09:54:05Z"],["dc.date.issued","2002"],["dc.description.abstract","A small electrode surface reduces pacing current drain and can extend generator longevity. The study evaluated the performance of a tined, quadripolar defibrillation lead (model 6944) that has a small-surfaced, steroid-eluting electrode tip for high impedance pacing. In a prospective, controlled study, 34 patients with conventional ICD indications were randomized one to one to receive the high impedance model 6944 or a tined defibrillation lead with a conventional sized, steroid-eluting electrode tip model 6942. Lead Performance was evaluated at implant, prior to hospital discharge, and 1, 3, 6, and 12 months thereafter. Baseline characteristics did not differ significantly between patients implanted with lead model 6942 (n = 16) or model 6944 (n = 17). One patient randomized to receive the model 6942 was excluded from the study and was implanted with an active-fixation lead after stable lead positioning was neither possible with the 6942 nor with the 6944 electrode. No other lead related adverse events were observed. At implant, there were no significant differences between pacing thresholds, sensing performance, defibrillation impedances, and defibrillation thresholds in both groups, but pacing impedance of the model 6944 (988.6 +/- 217.7 Omega) was approximately twice as high as in the model 6942 (431.7 +/- 83.7 Omega; P < 0.0001). This difference remained highly significant throughout the observation period of 12 months, while R wave amplitudes and pacing thresholds remained equal in both lead models. The use of a tined defibrillation lead with a small, steroid-eluting electrode tip appears safe and results in a high pacing impedance without compromising system performance."],["dc.identifier.doi","10.1046/j.1460-9592.2002.01577.x"],["dc.identifier.isi","000179508100007"],["dc.identifier.pmid","12494614"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36464"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Futura Publ Co"],["dc.relation.issn","0147-8389"],["dc.title","1-Year performance of a defibrillation lead with a small electrode surface for high impedance pacing: A randomized, controlled study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1066"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","American Heart Journal"],["dc.bibliographiccitation.lastpage","1070"],["dc.bibliographiccitation.volume","146"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Ahern, T."],["dc.contributor.author","Gerritse, B."],["dc.contributor.author","Canby, R. C."],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Binner, L."],["dc.contributor.author","Kimber, SKM"],["dc.contributor.author","Unterberg, Christina"],["dc.date.accessioned","2018-11-07T10:34:11Z"],["dc.date.available","2018-11-07T10:34:11Z"],["dc.date.issued","2003"],["dc.description.abstract","Background Pacing leads with a small electrode surface for high-impedance stimulation have been shown to prolong pacemaker longevity, but no sufficient data is available on the safety and feasibility of a defibrillation lead with this novel design. Methods We evaluated the clinical performance of a tined, steroid-eluting defibrillation lead with a small electrode surface area (model 6944) in a prospective multicenter study. A total of 542 patients with conventional indications for an implantable cardioverter defibrillator were randomized 1 : 1 to receive either the model 6944 or a tined, steroid-eluting defibrillation lead with a conventional sized electrode surface area (model 6942). Device performance and electrical parameters were evaluated at implant and 1, 3, 6, and 12 months thereafter (mean follow-up 11.3 +/- 5.6 months). Results Baseline characteristics, lead implant success rates, and defibrillation thresholds did not differ significantly between the 2 groups. While pacing thresholds did not differ significantly during follow-up, pacing impedance was approximately twice as high in the model 6944 as in the model 6942 lead (P <.0001). Mean R-wave amplitudes were smaller in patients with a 6944 (9.1 +/- 3.1 mV vs 9.8 +/- 3.6 mV for model 6942, P <.05), but remained stable within both groups throughout the observation period. The total number of ventricular lead-related adverse events and patient survival did not differ significantly between the 2 groups. Conclusions The use of a defibrillation lead with a small electrode surface for high-efficiency pacing is safe and feasible and increases pacing impedance without significantly compromising clinical performance."],["dc.identifier.doi","10.1016/S0002-8703(03)00411-3"],["dc.identifier.isi","187080200025"],["dc.identifier.pmid","14661000"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44798"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Mosby, Inc"],["dc.relation.issn","0002-8703"],["dc.title","Worldwide evaluation of a defibrillation lead with a small geometric electrode surface for high-impedance pacing"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of the American College of Cardiology"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Unterberg, Christina"],["dc.contributor.author","Stevens, J."],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Krieglstein, H."],["dc.contributor.author","Zenker, Dieter"],["dc.date.accessioned","2018-11-07T09:24:55Z"],["dc.date.available","2018-11-07T09:24:55Z"],["dc.date.issued","2001"],["dc.format.extent","123A"],["dc.identifier.isi","000166914400567"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29945"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.publisher.place","New york"],["dc.relation.issn","0735-1097"],["dc.title","Randomized comparison between a low and a new high impedance true bipolar defibrillation lead"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","716"],["dc.bibliographiccitation.issue","6-7"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","722"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Drescher, Till"],["dc.contributor.author","Schott, Peter"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Unterberg, Christina"],["dc.date.accessioned","2017-09-07T11:49:28Z"],["dc.date.available","2017-09-07T11:49:28Z"],["dc.date.issued","2007"],["dc.description.abstract","Background: An alert algorithm, based on intrathoracic impedance monitoring, has been incorporated into a cardiac resynchronisation device (CRT) to detect pulmonary fluid accumulation, and to audibly alert patients to decompensating chronic heart failure (CHF). Aims: To evaluate this algorithm, alert events were correlated with changes in NT-proBNP concentration and CHF status. Methods and results: In a prospective observational study of 62 patients (89% male, aged 67 +/- 1 year), NT proBNP plasma concentrations, clinical CHF status, and device data were collected at enrolment, during regular follow-up and at device alerts. Over a mean follow-up of 27 +/- 2 weeks, pooled data indicated a weak, but significant inverse relationship between relative changes in intrathoracic impedance and NT proBNP (r=-0.3; p < 0.001). In 52 device alerts from 35 patients, NT proBNP increased by 66 +/- 19% from 2039 +/- 1331 pg/ml (p < 0.001). The increase in NT proBNP was higher in alerts with clinical signs of CHF deterioration (n = 30, 89 +/- 25%;p < 0.001) than in alert events without clinical signs (n = 22, 25 +/- 15%; p = n.s.). Conclusion: Intrathoracic impedance based alert events are associated with a significant increase in NT-proBNP concentration. These data indicate that intrathoracic impedance monitoring might facilitate the outpatient management of CHF patients with implanted CRT devices. 2007 European Society of Cardiology. Published by Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.ejheart.2007.03.005"],["dc.identifier.gro","3143490"],["dc.identifier.isi","000247148900024"],["dc.identifier.pmid","17462948"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1009"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1388-9842"],["dc.title","Intrathoracic impedance monitoring to detect chronic heart failure deterioration: Relationship to changes in NT proBNP"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","457"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Pacing and Clinical Electrophysiology"],["dc.bibliographiccitation.lastpage","460"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Domhof, S."],["dc.contributor.author","Unterberg, Christina"],["dc.date.accessioned","2018-11-07T10:42:49Z"],["dc.date.available","2018-11-07T10:42:49Z"],["dc.date.issued","2003"],["dc.description.abstract","The high energy lead impedance is valuable for detecting lead failure in ICDs, but until recently shock delivery was necessary for high energy impedance measurement. This study compared the use of subthreshold test pulses and low energy test shocks to estimate the high energy impedance. Immediately after implantation of Ventak Prizm ICDs in 29 patients, the lead impedance was measured with five subthreshold (0.4 muJ) test pulses, 5 low energy (1.1 J) shocks, and two to three high energy (16 +/- 4.5 J) shocks. The mean impedances measured using high energy shocks, low energy shocks, and subthreshold pulses were 42.0 +/- 7.3 Omega, 46.5 +/- 8.1 Omega, and 42.4 +/- 7.1 Omega, respectively. The impedances measured using high and low energy shocks differed significantly (P < 0.0001), while those obtained by high energy shocks and low energy pulses did not (P = 0.63). According to-the Pearson correlation coefficient, the impedance measurements with subthreshold pulses and low energy shocks were both closely correlated (P < 0.0001) with impedance values determined with high energy shocks. However, while the impedance values tended to be higher when measured with low energy shocks, the concordance correlation coefficient (c) was higher for subthreshold test pulse versus high energy shock (c = 0.92) than for low versus high energy shock (c = 0.73). Furthermore, the intraindividual variability of impedance measurements was lower with subthreshold pulse measurements than with low energy shocks. Compared with low energy shocks, impedance measurement with subthreshold pulses has higher reproducibility and a higher correlation with the impedance obtained by high energy shock delivery. Safe and painless high energy impedance estimation with subthreshold pulses might, therefore, help to detect ICD lead failure during routine follow-up."],["dc.identifier.doi","10.1046/j.1460-9592.2003.00071.x"],["dc.identifier.isi","000181906600071"],["dc.identifier.pmid","12687867"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/46891"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Futura Publ Co"],["dc.publisher.place","Armonk"],["dc.relation.conference","Cardiostim 2002 Conference"],["dc.relation.eventlocation","NICE, FRANCE"],["dc.relation.issn","0147-8389"],["dc.title","Subthreshold test pulses versus low energy shock delivery to estimate high energy lead impedance in implanted cardioverter defibrillator patients"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]