Tuoc, Tran

[["dc.bibliographiccitation.firstpage","256"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Developmental Cell"],["dc.bibliographiccitation.lastpage","269"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Tuoc, Tran Cong"],["dc.contributor.author","Boretius, Susann"],["dc.contributor.author","Sansom, Stephen N."],["dc.contributor.author","Pitulescu, Mara-Elena"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Livesey, Frederick J."],["dc.contributor.author","Stoykova, Anastassia"],["dc.date.accessioned","2017-09-07T11:44:52Z"],["dc.date.available","2017-09-07T11:44:52Z"],["dc.date.issued","2013"],["dc.description.abstract","Increased cortical size is essential to the enhanced intellectual capacity of primates during mammalian evolution. The mechanisms that control cortical size are largely unknown. Here, we show that mammalian BAF170, a subunit of the chromatin remodeling complex mSWI/SNF, is an intrinsic factor that controls cortical size. We find that conditional deletion of BAF170 promotes indirect neurogenesis by increasing the pool of intermediate progenitors (IPs) and results in an enlarged cortex, whereas cortex-specific BAF170 overexpression results in the opposite phenotype. Mechanistically, BAF170 competes with BAF155 subunit in the BAF complex, affecting euchromatin structure and thereby modulating the binding efficiency of the Pax6/REST-corepressor complex to Pax6 target genes that regulate the generation of IPs and late cortical progenitors. Our findings reveal a molecular mechanism mediated by the mSWI/SNF chromatin-remodeling complex that controls cortical architecture."],["dc.identifier.doi","10.1016/j.devcel.2013.04.005"],["dc.identifier.gro","3150356"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7111"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.relation.issn","1534-5807"],["dc.title","Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","109"],["dc.bibliographiccitation.journal","iScience"],["dc.bibliographiccitation.lastpage","126"],["dc.bibliographiccitation.volume","4"],["dc.contributor.author","Narayanan, Ramanathan"],["dc.contributor.author","Pham, Linh"],["dc.contributor.author","Kerimoglu, Cemil"],["dc.contributor.author","Watanabe, Takashi"],["dc.contributor.author","Castro Hernandez, Ricardo"],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Ulmke, Pauline Antonie"],["dc.contributor.author","Kiszka, Kamila A."],["dc.contributor.author","Tonchev, Anton B."],["dc.contributor.author","Rosenbusch, Joachim"],["dc.contributor.author","Seong, Rho H."],["dc.contributor.author","Teichmann, Ulrike"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Fischer, Andre"],["dc.contributor.author","Bonn, Stefan"],["dc.contributor.author","Stoykova, Anastassia"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Tuoc, Tran"],["dc.date.accessioned","2020-12-10T14:24:42Z"],["dc.date.available","2020-12-10T14:24:42Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.isci.2018.05.014"],["dc.identifier.issn","2589-0042"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72326"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","303"],["dc.bibliographiccitation.journal","Neuroscience"],["dc.bibliographiccitation.lastpage","316"],["dc.bibliographiccitation.volume","463"],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Rosenbusch, Joachim"],["dc.contributor.author","Kunwar, Ajaya J."],["dc.contributor.author","Rickmann, Michael"],["dc.contributor.author","Tuoc, Tran"],["dc.contributor.author","Rizzoli, Silvio O."],["dc.contributor.author","Tarabykin, Victor"],["dc.contributor.author","von Mollard, Gabriele Fischer"],["dc.contributor.author","Krieglstein, Kerstin"],["dc.contributor.author","Staiger, Jochen F."],["dc.date.accessioned","2021-06-01T09:41:26Z"],["dc.date.available","2021-06-01T09:41:26Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1016/j.neuroscience.2021.03.021"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/84922"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","0306-4522"],["dc.title","Ablation of Vti1a/1b Triggers Neural Progenitor Pool Depletion and Cortical Layer 5 Malformation in Late-embryonic Mouse Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","8306"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Molecular Neurobiology"],["dc.bibliographiccitation.lastpage","8327"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Abbas, Eman"],["dc.contributor.author","Rosenbusch, Joachim"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Tuoc, Tran"],["dc.date.accessioned","2020-12-10T14:14:27Z"],["dc.date.available","2020-12-10T14:14:27Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1007/s12035-018-0987-y"],["dc.identifier.eissn","1559-1182"],["dc.identifier.issn","0893-7648"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71347"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Transcriptional and Epigenetic Control of Mammalian Olfactory Epithelium Development"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","38"],["dc.bibliographiccitation.journal","Science Advances"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Kerimoglu, Cemil"],["dc.contributor.author","Pham, Linh"],["dc.contributor.author","Tonchev, Anton B."],["dc.contributor.author","Sakib, M. Sadman"],["dc.contributor.author","Xie, Yuanbin"],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Ulmke, Pauline Antonie"],["dc.contributor.author","Kaurani, Lalit"],["dc.contributor.author","Abbas, Eman"],["dc.contributor.author","Nguyen, Huong"],["dc.contributor.author","Tuoc, Tran"],["dc.date.accessioned","2021-10-01T09:58:33Z"],["dc.date.available","2021-10-01T09:58:33Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1126/sciadv.abc6792"],["dc.identifier.pmid","34524839"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/90085"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/341"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-469"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation.eissn","2375-2548"],["dc.relation.workinggroup","RG A. Fischer (Epigenetics and Systems Medicine in Neurodegenerative Diseases)"],["dc.title","H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e1009446"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","PLoS Genetics"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Bi-Lin, Kathleen Wung"],["dc.contributor.author","Seshachalam, Pratap Veerabrahma"],["dc.contributor.author","Tuoc, Tran"],["dc.contributor.author","Stoykova, Anastassia"],["dc.contributor.author","Ghosh, Sujoy"],["dc.contributor.author","Singh, Manvendra K."],["dc.contributor.editor","Conlon, Frank L."],["dc.date.accessioned","2021-04-14T08:28:04Z"],["dc.date.available","2021-04-14T08:28:04Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1371/journal.pgen.1009446"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82496"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1553-7404"],["dc.title","Critical role of the BAF chromatin remodeling complex during murine neural crest development"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1317"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Cell Cycle"],["dc.bibliographiccitation.lastpage","1324"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Nguyen, Huong"],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Pham, Linh"],["dc.contributor.author","Rosenbusch, Joachim"],["dc.contributor.author","Stoykova, Anastassia"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Tuoc, Tran"],["dc.date.accessioned","2018-11-07T10:20:16Z"],["dc.date.available","2018-11-07T10:20:16Z"],["dc.date.issued","2016"],["dc.description.abstract","The multi-subunit chromatin-remodeling SWI/SNF (known as BAF for Brg/Brm-associated factor) complexes play essential roles in development. Studies have shown that the loss of individual BAF subunits often affects local chromatin structure and specific transcriptional programs. However, we do not fully understand how BAF complexes function in development because no animal mutant had been engineered to lack entire multi-subunit BAF complexes. Importantly, we recently reported that double conditional knock-out (dcKO) of the BAF155 and BAF170 core subunits in mice abolished the presence of the other BAF subunits in the developing cortex. The generated dcKO mutant provides a novel and powerful tool for investigating how entire BAF complexes affect cortical development. Using this model, we found that BAF complexes globally control the key heterochromatin marks, H3K27me2 and -3, by directly modulating the enzymatic activity of the H3K27 demethylases, Utx and Jmjd3. Here, we present further insights into how the scaffolding ability of the BAF155 and BAF170 core subunits maintains the stability of BAF complexes in the forebrain and throughout the embryo during development. Furthermore, we show that the loss of BAF complexes in the above-described model up-regulates H3K27me3 and impairs forebrain development and embryogenesis. These findings improve our understanding of epigenetic mechanisms and their modulation by the chromatin-remodeling SWI/SNF complexes that control embryonic development."],["dc.identifier.doi","10.1080/15384101.2016.1160984"],["dc.identifier.isi","000378726100007"],["dc.identifier.pmid","26986003"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41849"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1551-4005"],["dc.relation.issn","1538-4101"],["dc.title","Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","dev188276"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Development"],["dc.bibliographiccitation.volume","148"],["dc.contributor.author","Ulmke, Pauline Antonie"],["dc.contributor.author","Xie, Yuanbin"],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Pham, Linh"],["dc.contributor.author","Shomroni, Orr"],["dc.contributor.author","Berulava, Tea"],["dc.contributor.author","Rosenbusch, Joachim"],["dc.contributor.author","Basu, Uttiya"],["dc.contributor.author","Fischer, Andre"],["dc.contributor.author","Nguyen, Huu Phuc"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Tuoc, Tran"],["dc.date.accessioned","2021-04-14T08:28:06Z"],["dc.date.available","2021-04-14T08:28:06Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1242/dev.188276"],["dc.identifier.pmid","33462115"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82504"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/230"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation.eissn","1477-9129"],["dc.relation.issn","0950-1991"],["dc.relation.workinggroup","RG A. Fischer (Epigenetics and Systems Medicine in Neurodegenerative Diseases)"],["dc.title","Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1734"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Stem Cell Reports"],["dc.bibliographiccitation.lastpage","1750"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Nguyen, Huong"],["dc.contributor.author","Kerimoglu, Cemil"],["dc.contributor.author","Pirouz, Mehdi"],["dc.contributor.author","Pham, Linh"],["dc.contributor.author","Kiszka, Kamila A."],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Sakib, M. Sadman"],["dc.contributor.author","Rosenbusch, Joachim"],["dc.contributor.author","Teichmann, Ulrike"],["dc.contributor.author","Seong, Rho H."],["dc.contributor.author","Stoykova, Anastassia"],["dc.contributor.author","Fischer, Andre"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Tuoc, Tran"],["dc.date.accessioned","2020-12-10T15:21:29Z"],["dc.date.available","2020-12-10T15:21:29Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.stemcr.2018.04.014"],["dc.identifier.issn","2213-6711"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73043"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Epigenetic Regulation by BAF Complexes Limits Neural Stem Cell Proliferation by Suppressing Wnt Signaling in Late Embryonic Development"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","7305"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Molecular Neurobiology"],["dc.bibliographiccitation.lastpage","7320"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Xie, Yuanbin"],["dc.contributor.author","Castro-Hernández, Ricardo"],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Pham, Linh"],["dc.contributor.author","Narayanan, Ramanathan"],["dc.contributor.author","Rosenbusch, Joachim"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Tuoc, Tran"],["dc.date.accessioned","2020-12-10T14:14:29Z"],["dc.date.available","2020-12-10T14:14:29Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1007/s12035-019-1595-1"],["dc.identifier.eissn","1559-1182"],["dc.identifier.issn","0893-7648"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71355"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","RBM15 Modulates the Function of Chromatin Remodeling Factor BAF155 Through RNA Methylation in Developing Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]