Witt, Annette

[["dc.bibliographiccitation.artnumber","e1002438"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","PLoS Computational Biology"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Battaglia, Demian"],["dc.contributor.author","Witt, Annette"],["dc.contributor.author","Wolf, Fred"],["dc.contributor.author","Geisel, Theo"],["dc.date.accessioned","2017-09-07T11:46:13Z"],["dc.date.available","2017-09-07T11:46:13Z"],["dc.date.issued","2012"],["dc.description.abstract","Anatomic connections between brain areas affect information flow between neuronal circuits and the synchronization of neuronal activity. However, such structural connectivity does not coincide with effective connectivity (or, more precisely, causal connectivity), related to the elusive question “Which areas cause the present activity of which others?”. Effective connectivity is directed and depends flexibly on contexts and tasks. Here we show that dynamic effective connectivity can emerge from transitions in the collective organization of coherent neural activity. Integrating simulation and semi-analytic approaches, we study mesoscale network motifs of interacting cortical areas, modeled as large random networks of spiking neurons or as simple rate units. Through a causal analysis of time-series of model neural activity, we show that different dynamical states generated by a same structural connectivity motif correspond to distinct effective connectivity motifs. Such effective motifs can display a dominant directionality, due to spontaneous symmetry breaking and effective entrainment between local brain rhythms, although all connections in the considered structural motifs are reciprocal. We show then that transitions between effective connectivity configurations (like, for instance, reversal in the direction of inter-areal interactions) can be triggered reliably by brief perturbation inputs, properly timed with respect to an ongoing local oscillation, without the need for plastic synaptic changes. Finally, we analyze how the information encoded in spiking patterns of a local neuronal population is propagated across a fixed structural connectivity motif, demonstrating that changes in the active effective connectivity regulate both the efficiency and the directionality of information transfer. Previous studies stressed the role played by coherent oscillations in establishing efficient communication between distant areas. Going beyond these early proposals, we advance here that dynamic interactions between brain rhythms provide as well the basis for the self-organized control of this “communication-through-coherence”, making thus possible a fast “on-demand” reconfiguration of global information routing modalities."],["dc.identifier.doi","10.1371/journal.pcbi.1002438"],["dc.identifier.gro","3151853"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7868"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8682"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","public"],["dc.notes.submitter","chake"],["dc.relation.issn","1553-7358"],["dc.rights","CC BY 2.5"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.5"],["dc.title","Dynamic Effective Connectivity of Inter-Areal Brain Circuits"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e26457"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Hennig, Holger"],["dc.contributor.author","Fleischmann, Ragnar"],["dc.contributor.author","Fredebohm, Anneke"],["dc.contributor.author","Hagmayer, York"],["dc.contributor.author","Nagler, Jan"],["dc.contributor.author","Witt, Annette"],["dc.contributor.author","Theis, Fabian J."],["dc.contributor.author","Geisel, Theo"],["dc.date.accessioned","2018-11-07T08:50:38Z"],["dc.date.available","2018-11-07T08:50:38Z"],["dc.date.issued","2011"],["dc.description.abstract","Although human musical performances represent one of the most valuable achievements of mankind, the best musicians perform imperfectly. Musical rhythms are not entirely accurate and thus inevitably deviate from the ideal beat pattern. Nevertheless, computer generated perfect beat patterns are frequently devalued by listeners due to a perceived lack of human touch. Professional audio editing software therefore offers a humanizing feature which artificially generates rhythmic fluctuations. However, the built-in humanizing units are essentially random number generators producing only simple uncorrelated fluctuations. Here, for the first time, we establish long-range fluctuations as an inevitable natural companion of both simple and complex human rhythmic performances. Moreover, we demonstrate that listeners strongly prefer long-range correlated fluctuations in musical rhythms. Thus, the favorable fluctuation type for humanizing interbeat intervals coincides with the one generically inherent in human musical performances."],["dc.identifier.doi","10.1371/journal.pone.0026457"],["dc.identifier.isi","000296519600019"],["dc.identifier.pmid","22046289"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8345"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21739"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 2.5"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.5"],["dc.title","The Nature and Perception of Fluctuations in Human Musical Rhythms"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]