Now showing 1 - 10 of 42
  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","77"],["dc.bibliographiccitation.journal","Journal of Fluency Disorders"],["dc.bibliographiccitation.lastpage","85"],["dc.bibliographiccitation.volume","58"],["dc.contributor.author","Karimi, Hamid"],["dc.contributor.author","Onslow, Mark"],["dc.contributor.author","Jones, Mark"],["dc.contributor.author","O’Brian, Sue"],["dc.contributor.author","Packman, Ann"],["dc.contributor.author","Menzies, Ross"],["dc.contributor.author","Reilly, Sheena"],["dc.contributor.author","Sommer, Martin"],["dc.contributor.author","Jelčić-Jakšić, Suzana"],["dc.date.accessioned","2020-12-10T14:25:09Z"],["dc.date.available","2020-12-10T14:25:09Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.jfludis.2018.10.002"],["dc.identifier.issn","0094-730X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72456"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation.haserratum","/handle/2/82742"],["dc.title","The Satisfaction with Communication in Everyday Speaking Situations (SCESS) scale: An overarching outcome measure of treatment effect"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
    Details DOI
  • 2022Journal Article
    [["dc.bibliographiccitation.artnumber","S0304394022002129"],["dc.bibliographiccitation.firstpage","136655"],["dc.bibliographiccitation.journal","Neuroscience Letters"],["dc.contributor.author","Packman, Ann"],["dc.contributor.author","Onslow, Mark"],["dc.contributor.author","Lagopoulos, Jim"],["dc.contributor.author","Shan, Zack Y."],["dc.contributor.author","Lowe, Robyn"],["dc.contributor.author","Jones, Monique"],["dc.contributor.author","O'Brian, Sue"],["dc.contributor.author","Sommer, Martin"],["dc.date.accessioned","2022-05-02T07:46:58Z"],["dc.date.available","2022-05-02T07:46:58Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/j.neulet.2022.136655"],["dc.identifier.pii","S0304394022002129"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107179"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-561"],["dc.relation.issn","0304-3940"],["dc.title","White matter connectivity in neonates at risk of stuttering: Preliminary data"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
    Details DOI
  • 2010Journal Article
    [["dc.bibliographiccitation.firstpage","1915"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Clinical Neurophysiology"],["dc.bibliographiccitation.lastpage","1921"],["dc.bibliographiccitation.volume","121"],["dc.contributor.author","Rothkegel, Holger"],["dc.contributor.author","Sommer, M."],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Lang, N."],["dc.date.accessioned","2018-11-07T08:37:23Z"],["dc.date.available","2018-11-07T08:37:23Z"],["dc.date.issued","2010"],["dc.description.abstract","Objective: The intensity of transcranial magnetic stimulation (TMS) is typically adjusted by changing the amplitude of the induced electrical field, while its duration is fixed. Here we examined the influence of two different pulse durations on several physiological parameters of primary motor cortex excitability obtained using single pulse TMS. Methods: A Magstim Bistim(2) stimulator was used to produce TMS pulses of two distinct durations. For either pulse duration we measured, in healthy volunteers, resting and active motor thresholds, recruitment curves of motor evoked potentials in relaxed and contracting hand muscles as well as contralateral (cSP) and ipsilateral (iSP) cortical silent periods. Results: Motor thresholds decreased by 20% using a 1.4 times longer TMS pulse compared to the standard pulse, while there was no significant effect on threshold adjusted measurements of cortical excitability. The longer pulse duration reduced pulse-to-pulse variability in cSP. Conclusions: The strength of a TMS pulse can be adjusted both by amplitude or pulse duration. TMS pulse duration does not affect threshold-adjusted single pulse measures of motor cortex excitability. Significance: Using longer TMS pulses might be an alternative in subjects with very high motor threshold. Pulse duration might not be relevant as long as TMS intensity is threshold-adapted. This is important when comparing studies performed with different stimulator types. (C) 2010 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved."],["dc.description.sponsorship","DFG (Deutsche Forschungsgemeinschaft) [SO 429/2-2]; Rose Foundation"],["dc.identifier.doi","10.1016/j.clinph.2010.04.006"],["dc.identifier.isi","000282158200017"],["dc.identifier.pmid","20444645"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18520"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","1388-2457"],["dc.title","Impact of pulse duration in single pulse TMS"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC WOS
  • 2021Journal Article
    [["dc.bibliographiccitation.firstpage","2904"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Brain"],["dc.bibliographiccitation.lastpage","2905"],["dc.bibliographiccitation.volume","144"],["dc.contributor.author","Sommer, Martin"],["dc.contributor.author","SheikhBahaei, Shahriar"],["dc.contributor.author","Maguire, Gerald A"],["dc.date.accessioned","2022-01-11T14:08:07Z"],["dc.date.available","2022-01-11T14:08:07Z"],["dc.date.issued","2021"],["dc.description.abstract","This scientific commentary refers to \\‘Elevated iron concentration in putamen and cortical speech motor network in developmental stuttering\\’, by Cler et al. (doi:10.1093/brain/awab283)."],["dc.description.abstract","This scientific commentary refers to ‘Elevated iron concentration in putamen and cortical speech motor network in developmental stuttering’, by Cler et al. (doi:10.1093/brain/awab283)."],["dc.identifier.doi","10.1093/brain/awab348"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/97939"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-507"],["dc.relation.eissn","1460-2156"],["dc.relation.issn","0006-8950"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0/"],["dc.title","An unexpected iron in the fire of speech production"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
    Details DOI
  • 2001Journal Article
    [["dc.bibliographiccitation.firstpage","275"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Clinical Neurophysiology"],["dc.bibliographiccitation.lastpage","279"],["dc.bibliographiccitation.volume","112"],["dc.contributor.author","Wischer, Stephan"],["dc.contributor.author","Paulus, Walter"],["dc.contributor.author","Sommer, Martin"],["dc.contributor.author","Tergau, Frithjof"],["dc.date.accessioned","2021-06-01T10:50:21Z"],["dc.date.available","2021-06-01T10:50:21Z"],["dc.date.issued","2001"],["dc.description.abstract","Objective: To investigate by means of transcranial magnetic stimulation (TMS) the effect of a single oral dose of the GABA derivate piracetam on intracortical Facilitatory I-wave interaction. Methods: The study was performed in 8 healthy volunteers. Before, 1, 3, 6, and 24 h after intake of 4000 mg piracetam. MEPs in the relaxed abductor digiti minimi muscle were elicited by a recently introduced double pulse TMS technique with a suprathreshold first and a subthreshold second stimulus. From interstimulus intervals of 0.5-5.1 ms 3 periods were observed in which MEP facilitation showed maxima - so-called peaks of I-wave interaction - and which were separated by two troughs with no facilitation. We studied the changes in timing and size of the peaks over time. Results: With piracetam, I-wave peaks showed a reduction in size as well as a shortening of the latencies at which the peaks occurred. Both changes were significant at 6 h after drug intake compared to baseline. The effects were partially reversible after 24 h. Conclusions: The mode of action of piracetam within the nervous system is almost unknown. The peak size reduction was similar to effects that were seen under GABAergic drugs, although GABAergic properties of piracetam have not been observed so far. Shortening of the I-wave peak latencies is a new phenomenon. The results are discussed on the basis of the known therapeutic effects of piracetam in cortical myoclonus and as nootropic agent. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/S1388-2457(00)00548-4"],["dc.identifier.isi","000167058100007"],["dc.identifier.pmid","11165529"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86626"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Sci Ireland Ltd"],["dc.relation.issn","1388-2457"],["dc.title","Piracetam affects facilitatory I-wave interaction in the human motor cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC WOS
  • 2011Journal Article
    [["dc.bibliographiccitation.firstpage","945"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Cortex"],["dc.bibliographiccitation.lastpage","954"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","Neef, Nicole E."],["dc.contributor.author","Jung, Kristina"],["dc.contributor.author","Rothkegel, Holger"],["dc.contributor.author","Pollok, Bettina"],["dc.contributor.author","von Gudenberg, Alexander Wolff"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Sommer, Martin"],["dc.date.accessioned","2018-11-07T08:53:01Z"],["dc.date.available","2018-11-07T08:53:01Z"],["dc.date.issued","2011"],["dc.description.abstract","Introduction: In adults who do not stutter (AWNS), the control of hand movement timing is assumed to be lateralized to the left dorsolateral premotor cortex (PMd). In adults who stutter (AWS), the network of speech motor control is abnormally shifted to the right hemisphere. Motor impairments in AWS are not restricted to speech, but extend to non-speech orofacial and finger movements. We here investigated the lateralization of finger movement timing control in AWS. Methods: We explored PMd function in 14 right-handed AWS and 15 age matched AWNS. In separate sessions, they received subthreshold repetitive transcranial magnetic stimulation (rTMS) for 20 min at 1 Hz over the left or right PMd, respectively. Pre- and post-stimulation participants were instructed to synchronize their index finger taps of either hand with an isochronous sequence of clicks presented binaurally via earphones. Synchronization accuracy was measured to quantify the effect of the PMd stimulation. Results: In AWNS inhibition of left PMd affected synchronization accuracy of the left hand. Conversely, in AWS TMS over the right PMd increased the asynchrony of the left hand. Conclusions: The present data indicate an altered functional connectivity in AWS in which the right PMd seems to be important for the control of timed non-speech movements. Moreover, the laterality-shift suggests a compensatory role of the right PMd to successfully perform paced finger tapping. (C) 2010 Elsevier Srl. All rights reserved."],["dc.identifier.doi","10.1016/j.cortex.2010.06.007"],["dc.identifier.isi","000293155300005"],["dc.identifier.pmid","20822768"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22305"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Masson"],["dc.relation.issn","0010-9452"],["dc.title","Right-shift for non-speech motor processing in adults who stutter"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC WOS
  • 2015Journal Article
    [["dc.bibliographiccitation.firstpage","712"],["dc.bibliographiccitation.journal","Brain"],["dc.bibliographiccitation.lastpage","725"],["dc.bibliographiccitation.volume","138"],["dc.contributor.author","Neef, Nicole E."],["dc.contributor.author","Hoang, T. N. Linh"],["dc.contributor.author","Neef, Andreas"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Sommer, Martin"],["dc.date.accessioned","2018-11-07T10:00:13Z"],["dc.date.available","2018-11-07T10:00:13Z"],["dc.date.issued","2015"],["dc.description.abstract","The precise excitability regulation of neuronal circuits in the primary motor cortex is central to the successful and fluent production of speech. Our question was whether the involuntary execution of undesirable movements, e.g. stuttering, is linked to an insufficient excitability tuning of neural populations in the orofacial region of the primary motor cortex. We determined the speech-related time course of excitability modulation in the left and right primary motor tongue representation. Thirteen fluent speakers (four females, nine males; aged 23-44) and 13 adults who stutter (four females, nine males, aged 21-55) were asked to build verbs with the verbal prefix 'auf'. Single-pulse transcranial magnetic stimulation was applied over the primary motor cortex during the transition phase between a fixed labiodental articulatory configuration and immediately following articulatory configurations, at different latencies after transition onset. Bilateral electromyography was recorded from self-adhesive electrodes placed on the surface of the tongue. Off-line, we extracted the motor evoked potential amplitudes and normalized these amplitudes to the individual baseline excitability during the fixed configuration. Fluent speakers demonstrated a prominent left hemisphere increase of motor cortex excitability in the transition phase (P = 0.009). In contrast, the excitability of the right primary motor tongue representation was unchanged. Interestingly, adults afflicted with stuttering revealed a lack of left-hemisphere facilitation. Moreover, the magnitude of facilitation was negatively correlated with stuttering frequency. Although orofacial midline muscles are bilaterally innervated from corticobulbar projections of both hemispheres, our results indicate that speech motor plans are controlled primarily in the left primary speech motor cortex. This speech motor planning-related asymmetry towards the left orofacial motor cortex is missing in stuttering. Moreover, a negative correlation between the amount of facilitation and stuttering severity suggests that we discovered a main physiological principle of fluent speech production and its role in stuttering."],["dc.identifier.doi","10.1093/brain/awu390"],["dc.identifier.isi","000351510700026"],["dc.identifier.pmid","25595146"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37754"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1460-2156"],["dc.relation.issn","0006-8950"],["dc.title","Speech dynamics are coded in the left motor cortex in fluent speakers but not in adults who stutter"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC WOS
  • 2022Journal Article
    [["dc.bibliographiccitation.firstpage","84"],["dc.bibliographiccitation.journal","Clinical Neurophysiology"],["dc.bibliographiccitation.lastpage","96"],["dc.bibliographiccitation.volume","138"],["dc.contributor.author","Korzeczek, Alexandra"],["dc.contributor.author","Neef, Nicole E."],["dc.contributor.author","Steinmann, Iris"],["dc.contributor.author","Paulus, Walter"],["dc.contributor.author","Sommer, Martin"],["dc.date.accessioned","2022-05-02T08:09:50Z"],["dc.date.available","2022-05-02T08:09:50Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/j.clinph.2022.03.010"],["dc.identifier.pii","S1388245722002139"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107480"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-561"],["dc.relation.issn","1388-2457"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Stuttering severity relates to frontotemporal low-beta synchronization during pre-speech preparation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
    Details DOI
  • 2017Journal Article
    [["dc.bibliographiccitation.journal","Deutsches Ärzteblatt international"],["dc.contributor.author","Neumann, Katrin"],["dc.contributor.author","Euler, Harald A."],["dc.contributor.author","Bosshardt, Hans-Georg"],["dc.contributor.author","Cook, Susanne"],["dc.contributor.author","Sandrieser, Patricia"],["dc.contributor.author","Sommer, Martin"],["dc.date.accessioned","2020-12-10T18:44:15Z"],["dc.date.available","2020-12-10T18:44:15Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.3238/arztebl.2017.0383"],["dc.identifier.eissn","1866-0452"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78380"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","The Pathogenesis, Assessment and Treatment of Speech Fluency Disorders"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
    Details DOI
  • 2022Journal Article
    [["dc.bibliographiccitation.firstpage","90"],["dc.bibliographiccitation.journal","Clinical Neurophysiology"],["dc.bibliographiccitation.volume","141"],["dc.contributor.author","Sommer, Martin"],["dc.date.accessioned","2022-09-01T09:49:31Z"],["dc.date.available","2022-09-01T09:49:31Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/j.clinph.2022.07.367"],["dc.identifier.pii","S1388245722006939"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113446"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.issn","1388-2457"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Detecting and reporting the limits of rTMS"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
    Details DOI