Haehling, Stephan von

[["dc.bibliographiccitation.firstpage","6"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","12"],["dc.bibliographiccitation.volume","205"],["dc.contributor.author","Ebner, Nicole"],["dc.contributor.author","Jankowska, Ewa A."],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Lainscak, Mitja"],["dc.contributor.author","Elsner, Sebastian"],["dc.contributor.author","Sliziuk, Veronika"],["dc.contributor.author","Steinbeck, Lisa"],["dc.contributor.author","Kube, Jennifer"],["dc.contributor.author","Bekfani, Tarek"],["dc.contributor.author","Scherbakov, Nadja"],["dc.contributor.author","Valentova, Miroslava"],["dc.contributor.author","Sandek, Anja"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","Springer, Jochen"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","von Haehling, Stephan"],["dc.date.accessioned","2020-12-10T14:24:29Z"],["dc.date.available","2020-12-10T14:24:29Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1016/j.ijcard.2015.11.178"],["dc.identifier.issn","0167-5273"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72267"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","The impact of iron deficiency and anaemia on exercise capacity and outcomes in patients with chronic heart failure. Results from the Studies Investigating Co-morbidities Aggravating Heart Failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","19"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","21"],["dc.bibliographiccitation.volume","238"],["dc.contributor.author","Palus, Sandra"],["dc.contributor.author","Springer, J. I."],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","von Haehling, Stephan"],["dc.contributor.author","Anker, Markus S."],["dc.contributor.author","Anker, Stefan-D."],["dc.date.accessioned","2018-11-07T10:22:26Z"],["dc.date.available","2018-11-07T10:22:26Z"],["dc.date.issued","2017"],["dc.description.abstract","Approximately 40-50% of the population over 80 years of age suffers from sarcopenia making this condition a major geriatric clinical disorder and a key challenge to healthy aging. The hallmark symptom of sarcopenia is the loss of muscle mass and strength without the loss of overall body weight. Sarcopenic patients are likely to have worse clinical outcomes and higher mortality compared to healthy individuals. This review will focus on animal models designed to study sarcopenia including hind-limb unloading, de-nervation, and immobilization by using casts or wire strategies, as well as using aged rodents. Currently there are no registered treatments for sarcopenia. Most sarcopenic individuals show signs of physical frailty, which leads to increases the prevalence of balance disorders, falls, fractures and pain. Therefore, is it essential to develop and use relevant animal models to further the research on sarcopenia therapy? (C) 2017 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.ijcard.2017.03.152"],["dc.identifier.isi","000402478900004"],["dc.identifier.pmid","28465116"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42272"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","1874-1754"],["dc.relation.issn","0167-5273"],["dc.title","Models of sarcopenia: Short review"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Bekfani, T. Tarek"],["dc.contributor.author","Schoebel, C. H."],["dc.contributor.author","Pietrock, C. H."],["dc.contributor.author","Valentova, Miroslava"],["dc.contributor.author","Sandek, A."],["dc.contributor.author","Ebner, Nicole"],["dc.contributor.author","Elsner, Sebastian"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","Noutsias, M."],["dc.contributor.author","Schulze, P. C."],["dc.contributor.author","Anker, Stefan-D."],["dc.contributor.author","von Haehling, S."],["dc.date.accessioned","2018-11-07T10:24:09Z"],["dc.date.available","2018-11-07T10:24:09Z"],["dc.date.issued","2017"],["dc.format.extent","267"],["dc.identifier.isi","000401005300765"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42605"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Wiley"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1879-0844"],["dc.relation.issn","1388-9842"],["dc.title","A comparison between patients with central and obstructive sleep apnea in patients with heart failure: SICA-HF"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","297"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Endocrinological Investigation"],["dc.bibliographiccitation.lastpage","304"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Loncar, G. Goran"],["dc.contributor.author","Bozic, B."],["dc.contributor.author","Cvetinovic, N."],["dc.contributor.author","Dungen, H.-D."],["dc.contributor.author","Lainscak, Mitja"],["dc.contributor.author","von Haehling, Stephan"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","Radojicic, Z."],["dc.contributor.author","Putnikovic, Biljana"],["dc.contributor.author","Trippel, Tobias D."],["dc.contributor.author","Popovic, V."],["dc.date.accessioned","2018-11-07T10:26:42Z"],["dc.date.available","2018-11-07T10:26:42Z"],["dc.date.issued","2017"],["dc.description.abstract","Aim Evaluation of secondary hyperparathyroidism (SHPT) and its prognostic impact on all- cause mortality in elderly males with heart failure (HF). Methods Seventy three males (67 +/- 7 years old) with systolic HF were included. Baseline PTH was measured. Patients were grouped according to PTH cut- off levels of 65 pg/ ml (> 65 pg/ ml = SHPT vs. normal PTH). All- cause mortality was evaluated at 6- year follow- up. Results SHPT was diagnosed in 43 (59 %) patients. They were more severe compared to the patients with normal PTH regarding NYHA functional class (2.4 +/- 0.5 vs. 2.1 +/- 0.2, p = 0.001), quality of life score (34 +/- 14 vs. 24 +/- 12, p = 0.005), 6- min walking distance (378 +/- 79 vs. 446 +/- 73 m, p < 0.0001), left ventricular ejection fraction (27 +/- 8 vs. 31 +/- 7 %, p = 0.019), and NT- proBNP [2452 (3399) vs. 918 (1372) pg/ ml, p < 0.0001]. No differences in age, vitamin D status, and renal function were noted between studied groups. A total of 41 (56 %) patients died within 6 years of follow- up. Kaplan- Meier survival analysis showed impaired long- term survival in patients with SHPT versus patients with normal PTH ( p = 0.009). The rate of death was highest (75 %) in the group of patients with SHPT and NT- proBNP levels above median value ( p =0.003). Cox regression analysis demonstrated that NTproBNP was the single independent predictor of all- cause mortality at 6- year follow- up [HR 3.698 (1.927- 7.095), p < 0.0001]. Conclusion SHPT was highly prevalent in elderly males with HF and was associated with impaired survival. HF patients with SHPT had more severe disease compared to the patients with normal serum PTH. Determination of serum PTH levels provided additional value to NT- proBNP for risk stratification in these patients."],["dc.description.sponsorship","Serbian Ministry of Science [175033]"],["dc.identifier.doi","10.1007/s40618-016-0561-2"],["dc.identifier.isi","000397150300007"],["dc.identifier.pmid","27738907"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43099"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Springer"],["dc.relation.issn","1720-8386"],["dc.title","Secondary hyperparathyroidism prevalence and prognostic role in elderly males with heart failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2729"],["dc.bibliographiccitation.issue","40"],["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.lastpage","2732"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","von Haehling, Stephan"],["dc.contributor.author","Anker, Stefan-D."],["dc.date.accessioned","2018-11-07T09:50:03Z"],["dc.date.available","2018-11-07T09:50:03Z"],["dc.date.issued","2015"],["dc.identifier.doi","10.1093/eurheartj/ehv414"],["dc.identifier.isi","000366488300012"],["dc.identifier.pmid","26341892"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35631"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1522-9645"],["dc.relation.issn","0195-668X"],["dc.title","Protective overweight in cardiovascular disease: moving from 'paradox' to 'paradigm'"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1550"],["dc.bibliographiccitation.issue","19"],["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.lastpage","1552"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","von Haehling, Stephan"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","Anker, Stefan D"],["dc.date.accessioned","2020-12-10T18:19:04Z"],["dc.date.available","2020-12-10T18:19:04Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1093/eurheartj/ehz082"],["dc.identifier.eissn","1522-9645"],["dc.identifier.issn","0195-668X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75126"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","The evolving obesity paradigm story: from heart failure to atrial fibrillation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of Cachexia, Sarcopenia and Muscle"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","Scherbakov, Nadja"],["dc.contributor.author","Schellenberg, Tim"],["dc.contributor.author","Jankowska, Ewa A."],["dc.contributor.author","Scheitz, Jan F."],["dc.contributor.author","Haehling, Stephan"],["dc.contributor.author","Joebges, Michael"],["dc.date.accessioned","2022-04-01T10:01:15Z"],["dc.date.available","2022-04-01T10:01:15Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1002/jcsm.12927"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105633"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.eissn","2190-6009"],["dc.relation.issn","2190-5991"],["dc.title","Iron deficiency is related to low functional outcome in patients at early rehabilitation after acute stroke"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Bekfani, T. Tarek"],["dc.contributor.author","Pellicori, Pierpaolo"],["dc.contributor.author","Ebner, Nicole"],["dc.contributor.author","Morris, Daniel A."],["dc.contributor.author","Sandek, A."],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","Cleland, John G. F."],["dc.contributor.author","Lainscak, Mitja"],["dc.contributor.author","Anker, Stefan-D."],["dc.contributor.author","von Haehling, S."],["dc.date.accessioned","2018-11-07T09:57:25Z"],["dc.date.available","2018-11-07T09:57:25Z"],["dc.date.issued","2015"],["dc.format.extent","277"],["dc.identifier.isi","000366200403082"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37152"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1879-0844"],["dc.relation.issn","1388-9842"],["dc.title","The prevalence of iron deficiency in patients with heart failure with preserved ejection fraction and its association with elevated pulmonary pressure, reduced exercise capacity and quality of life"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","48"],["dc.bibliographiccitation.journal","Journal of Molecular and Cellular Cardiology"],["dc.bibliographiccitation.lastpage","53"],["dc.bibliographiccitation.volume","87"],["dc.contributor.author","Ebner, Nicole"],["dc.contributor.author","Földes, Gabor"],["dc.contributor.author","Schomburg, Lutz"],["dc.contributor.author","Renko, Kostja"],["dc.contributor.author","Springer, Jochen"],["dc.contributor.author","Jankowska, Ewa A."],["dc.contributor.author","Sharma, Rakesh"],["dc.contributor.author","Genth-Zotz, Sabine"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","von Haehling, Stephan"],["dc.date.accessioned","2021-06-01T10:49:59Z"],["dc.date.available","2021-06-01T10:49:59Z"],["dc.date.issued","2015"],["dc.identifier.doi","10.1016/j.yjmcc.2015.07.029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86483"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","0022-2828"],["dc.title","Lipopolysaccharide responsiveness is an independent predictor of death in patients with chronic heart failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","497"],["dc.bibliographiccitation.journal","Wiener klinische Wochenschrift"],["dc.bibliographiccitation.lastpage","504"],["dc.bibliographiccitation.volume","128"],["dc.contributor.author","Saitoh, Masakazu"],["dc.contributor.author","dos Santos, Marcelo Rodrigues"],["dc.contributor.author","Ebner, Nicole"],["dc.contributor.author","Emami, Amir"],["dc.contributor.author","Konishi, Masaaki"],["dc.contributor.author","Ishida, Junichi"],["dc.contributor.author","Valentova, Miroslava"],["dc.contributor.author","Sandek, Anja"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","Anker, Stefan-D."],["dc.contributor.author","von Haehling, Stephan"],["dc.date.accessioned","2018-11-07T10:05:07Z"],["dc.date.available","2018-11-07T10:05:07Z"],["dc.date.issued","2016"],["dc.description.abstract","Inadequate nutritional status has been linked to poor outcomes in patients with heart failure (HF). Skeletal muscle wasting affects about 20% of ambulatory patients with HF. The impact of nutritional intake and appetite on skeletal muscle wasting has not been investigated so far. We sought to investigate the impact of nutritional status on muscle wasting and mortality in ambulatory patients with HF. We studied 130 ambulatory patients with HF who were recruited as a part of the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF) program. Muscle wasting was defined according to criteria of sarcopenia, i.e., appendicular skeletal muscle mass two standard deviations below the mean of a healthy reference group aged 18-40 years. Nutritional status was evaluated using the Mini-Nutritional Assessment-Short Form (MNA-SF). Functional capacity was assessed as peak oxygen consumption (peak VO2) by cardiopulmonary exercise testing, 6aEurominute walk testing, and the Short Physical Performance Battery (SPPB). At baseline, 19 patients (15%) presented with muscle wasting. Patients with muscle wasting had significantly lower values of peak VO2, 6aEurominute walk distance, SPPB, and MNA-SF score than patients without (all p < 0.05). In multivariate analysis, MNA-SF remained an independent predictor of muscle wasting after adjustment for age and New York Heart Association class (odds ratio [OR] 0.66; confidence interval [CI] 0.50-0.88; p < 0.01). A total of 16 (12%) patients died during a mean follow-up of 21 months. In Cox regression analysis, MNA-SF (OR 0.80, CI 0.64-0.99, p = 0.04), left ventricular ejection fraction (OR 0.93, CI 0.86-0.99, p = 0.05), and peak VO2 (OR 0.78, CI 0.65-0.94, p = 0.008) were predictors of death. MNA-SF is an independent predictor of muscle wasting and mortality in ambulatory patients with HF. Nutritional screening should be included as a fundamental part of the overall assessment of these patients."],["dc.identifier.doi","10.1007/s00508-016-1112-8"],["dc.identifier.isi","000390034100011"],["dc.identifier.pmid","27853883"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38838"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","1613-7671"],["dc.relation.issn","0043-5325"],["dc.title","Nutritional status and its effects on muscle wasting in patients with chronic heart failure: insights from Studies Investigating Co-morbidities Aggravating Heart Failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]