Ritter, Christian Oliver

[["dc.bibliographiccitation.firstpage","1149"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","European Radiology"],["dc.bibliographiccitation.lastpage","1156"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Krüwel, Thomas"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Stahnke, Vera C."],["dc.contributor.author","Rave-Fränk, Margret"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Sohns, Jan M."],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Ritter, Christian"],["dc.contributor.author","Lotz, Joachim"],["dc.date.accessioned","2020-12-10T14:10:11Z"],["dc.date.available","2020-12-10T14:10:11Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00330-017-5056-9"],["dc.identifier.eissn","1432-1084"],["dc.identifier.issn","0938-7994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70672"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Absence of DNA double-strand breaks in human peripheral blood mononuclear cells after 3 Tesla magnetic resonance imaging assessed by γH2AX flow cytometry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","102862"],["dc.bibliographiccitation.journal","EBioMedicine"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Wolfien, Markus"],["dc.contributor.author","Klatt, Denise"],["dc.contributor.author","Salybekov, Amankeldi A."],["dc.contributor.author","Ii, Masaaki"],["dc.contributor.author","Komatsu-Horii, Miki"],["dc.contributor.author","Gaebel, Ralf"],["dc.contributor.author","Philippou-Massier, Julia"],["dc.contributor.author","Schrinner, Eric"],["dc.contributor.author","Akimaru, Hiroshi"],["dc.contributor.author","Akimaru, Erika"],["dc.contributor.author","David, Robert"],["dc.contributor.author","Garbade, Jens"],["dc.contributor.author","Gummert, Jan"],["dc.contributor.author","Haverich, Axel"],["dc.contributor.author","Hennig, Holger"],["dc.contributor.author","Iwasaki, Hiroto"],["dc.contributor.author","Kaminski, Alexander"],["dc.contributor.author","Kawamoto, Atsuhiko"],["dc.contributor.author","Klopsch, Christian"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Krebs, Stefan"],["dc.contributor.author","Nesteruk, Julia"],["dc.contributor.author","Reichenspurner, Hermann"],["dc.contributor.author","Ritter, Christian"],["dc.contributor.author","Stamm, Christof"],["dc.contributor.author","Tani-Yokoyama, Ayumi"],["dc.contributor.author","Blum, Helmut"],["dc.contributor.author","Wolkenhauer, Olaf"],["dc.contributor.author","Schambach, Axel"],["dc.contributor.author","Asahara, Takayuki"],["dc.contributor.author","Steinhoff, Gustav"],["dc.date.accessioned","2021-04-14T08:26:01Z"],["dc.date.available","2021-04-14T08:26:01Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.ebiom.2020.102862"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81807"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.issn","2352-3964"],["dc.title","Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","8"],["dc.bibliographiccitation.journal","Experimental Neurology"],["dc.bibliographiccitation.lastpage","21"],["dc.bibliographiccitation.volume","265"],["dc.contributor.author","Geis, Christian"],["dc.contributor.author","Ritter, Christian"],["dc.contributor.author","Ruschil, Christoph"],["dc.contributor.author","Weishaupt, Andreas"],["dc.contributor.author","Gruenewald, Benedikt"],["dc.contributor.author","Stoll, Guido"],["dc.contributor.author","Holmoy, Trygve"],["dc.contributor.author","Misu, Tatsuro"],["dc.contributor.author","Fujihara, Kazuo"],["dc.contributor.author","Hemmer, Bernhard"],["dc.contributor.author","Stadelmann, Christine"],["dc.contributor.author","Bennett, Jeffrey L."],["dc.contributor.author","Sommer, Claudia"],["dc.contributor.author","Toyka, Klaus V."],["dc.date.accessioned","2018-11-07T10:00:24Z"],["dc.date.available","2018-11-07T10:00:24Z"],["dc.date.issued","2015"],["dc.description.abstract","Neuromyelitis optica (NMO) is causally linked to autoantibodies (ABs) against aquaporin 4 (AQP4). Here, we focused on the pathogenic effects exclusively mediated by human ABs to AQP4 in vivo. We performed cell-free intrathecal (i.th.) passive transfer experiments in Lewis rats using purified patient NMO immunoglobulin G (IgG) and various recombinant human anti-AQP4 IgG-ABs via implanted i.th. catheters. Repetitive application of patient NMO IgG fractions and of recombinant human anti-AQP4 ABs induced signs of spinal cord disease. Magnetic resonance imaging (MRI) revealed longitudinal spinal cord lesions at the site of application of anti-AQP4 IgG. Somatosensory evoked potential amplitudes were reduced in symptomatic animals corroborating the observed functional impairment. Spinal cord histology showed specific IgG deposition in the grey and white matter in the affected areas. We did not find inflammatory cell infiltration nor activation of complement in spinal cord areas of immunoglobulin deposition. Moreover, destructive lesions showing axon or myelin damage and loss of astrocytes and oligodendrocytes were all absent. Immunoreactivity to AQP4 and to the excitatory amino acid transporter 2 (EAAT2) was markedly reduced whereas immunoreactivity to the astrocytic marker glial fibrillary acid protein (GFAP) was preserved. The expression of the NMDA-receptor NR1 subunit was down-regulated in areas of IgG deposition possibly induced by sustained glutamatergic overexcitation. Disease signs and histopathology were reversible within weeks after stopping injections. We conclude that in vivo application of ABs directed at AQP 4 can induce a reversible spinal cord disease in recipient rats by inducing distinct histopathological abnormalities. These findings may be the experimental correlate of \"penumbra-like\" lesions recently reported in NMO patients adjacent to effector-mediated tissue damage. (C) 2014 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.expneurol.2014.12.015"],["dc.identifier.isi","000351021900002"],["dc.identifier.pmid","25542977"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37800"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.relation.issn","1090-2430"],["dc.relation.issn","0014-4886"],["dc.title","The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1595"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Magnetic Resonance Imaging"],["dc.bibliographiccitation.lastpage","1601"],["dc.bibliographiccitation.volume","48"],["dc.contributor.author","Weng, Andreas M."],["dc.contributor.author","Wilimsky, Stefan"],["dc.contributor.author","Bender, Gwendolyn"],["dc.contributor.author","Hahner, Stefanie"],["dc.contributor.author","Köstler, Herbert"],["dc.contributor.author","Ritter, Christian O."],["dc.date.accessioned","2020-12-10T14:06:48Z"],["dc.date.available","2020-12-10T14:06:48Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1002/jmri.v48.6"],["dc.identifier.issn","1053-1807"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70026"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Magnetic resonance cold pressor test to investigate potential endothelial dysfunction in patients suffering from type 1 diabetes"],["dc.title.alternative","MR CPT in Type 1 Diabetics"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1761"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","The International Journal of Cardiovascular Imaging"],["dc.bibliographiccitation.lastpage","1769"],["dc.bibliographiccitation.volume","33"],["dc.contributor.author","Wandelt, Laura"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Stümpfig, Thomas"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Ritter, Christian Oliver"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Staab, Wieland"],["dc.date.accessioned","2018-10-10T11:47:58Z"],["dc.date.available","2018-10-10T11:47:58Z"],["dc.date.issued","2017-11"],["dc.description.abstract","Left atrial (LA) enlargement and dysfunction are markers of chronic diastolic dysfunction and an important predictor of adverse cardiovascular and cerebrovascular outcomes. Accordingly, accurate quantification of left atrial volume (LAV) and function is needed. In routine clinical cardiovascular magnetic resonance (CMR) imaging the biplane area-length method (Bi-ALM) is frequently applied due to time-saving image acquisition and analysis. However, given the varying anatomy of the LA we hypothesized that the diagnostic accuracy of the Bi-ALM is not sufficient and that results would be different from a precise volumetric assessment of transversal multi-slice cine images using Simpson's method. Thirty one patients of the FIND-AFRANDOMISED-study with status post acute cerebral ischemia (mean age 70.5 ± 6.2 years) received CMR imaging at 3T. The study protocol included cine SSFP sequences in standard 2- and 4 CV and a stack of contiguous slices in transversal orientation. Total, passive and active LA emptying fractions were calculated from LA maximal volume, minimal volume and volume prior to atrial contraction. Intra- and inter-observer variability was assessed in ten patients. Significant differences were found for LA volume and phasic function. The Bi-ALM significantly underestimated LA volume and overestimated LA function in comparison to Simpson's method (Bi-ALM vs. Simpson's method: LAVmax: 80.18 vs. 98.80 ml; LAVpre-ac: 61.09 vs. 80.41 ml; LAVmin: 36.85 vs. 52.66 ml; LAEFTotal: 55.17 vs. 47.85%; LAEFPassive: 23.96 vs. 19.15%; LAEFBooster: 40.87 vs. 35.64%). LA volumetric and functional parameters were reproducible on an intra- and inter-observer levels for both methods. Intra-observer agreement for LA function was better for Simpson's method (Bi-ALM vs. Simpson's method; ICC LAEFTotal: 0.84 vs. 0.96; ICC LAEFPassive: 0.74 vs. 0.92; ICC LAEFBooster: 0.86 vs. 0.89). The Bi-ALM is based on geometric assumptions that do not reflect the complex individual LA geometry. The assessment of transversal slices covering the left atrium with Simpson's method is feasible and might be more suitable for an accurate quantification of LA volume and phasic function."],["dc.identifier.doi","10.1007/s10554-017-1160-9"],["dc.identifier.gro","630663"],["dc.identifier.pmid","28523471"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15959"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1875-8312"],["dc.title","Quantification of left atrial volume and phasic function using cardiovascular magnetic resonance imaging-comparison of biplane area-length method and Simpson's method"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1356"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","European Radiology"],["dc.bibliographiccitation.lastpage","1365"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Weng, Andreas Max"],["dc.contributor.author","Ritter, Christian Oliver"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Beer, Meinrad Joachim"],["dc.contributor.author","Hahn, Dietbert"],["dc.contributor.author","Köstler, Herbert"],["dc.date.accessioned","2022-06-08T07:59:34Z"],["dc.date.available","2022-06-08T07:59:34Z"],["dc.date.issued","2009"],["dc.identifier.doi","10.1007/s00330-009-1684-z"],["dc.identifier.pii","1684"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/110790"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-575"],["dc.relation.eissn","1432-1084"],["dc.relation.issn","0938-7994"],["dc.title","Automatic postprocessing for the assessment of quantitative human myocardial perfusion using MRI"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","880"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Magnetic Resonance in Medicine"],["dc.bibliographiccitation.lastpage","887"],["dc.bibliographiccitation.volume","76"],["dc.contributor.author","Tran-Gia, Johannes"],["dc.contributor.author","Lohr, David"],["dc.contributor.author","Weng, Andreas Max"],["dc.contributor.author","Ritter, Christian Oliver"],["dc.contributor.author","Staeb, Daniel"],["dc.contributor.author","Bley, Thorsten Alexander"],["dc.contributor.author","Koestler, Herbert"],["dc.date.accessioned","2018-11-07T10:08:56Z"],["dc.date.available","2018-11-07T10:08:56Z"],["dc.date.issued","2016"],["dc.description.abstract","Purpose: To reduce saturation effects in the arterial input function (AIF) estimation of quantitative myocardial first-pass saturation recovery perfusion imaging by employing a model-based reconstruction. Theory and Methods: Imaging was performed with a saturation recovery prepared radial FLASH sequence. A model-based reconstruction was applied for reconstruction. By exploiting prior knowledge about the relaxation process, an image series with different saturation recovery times was reconstructed. By evaluating images with an effective saturation time of approximately 3 ms, saturation effects in the AIF determination were reduced. In a volunteer study, this approach was compared with a standard prebolus technique. Results: In comparison to the low-dose injection of a prebolus acquisition, saturation effects were further reduced in the AIFs determined using the model-based approach. These effects, which were clearly visible for all six volunteers, were reflected in a statistically significant difference of up to 20% in the absolute perfusion values. Conclusion: The application of model-based reconstruction algorithms in quantitative myocardial perfusion imaging promises a significant improvement of the AIF determination. In addition to greatly reducing saturation effects that occur even for the prebolus methods, only a single bolus has to be applied. (C) 2015 Wiley Periodicals, Inc."],["dc.description.sponsorship","Graduate School of Life Sciences, University of Wurzburg"],["dc.identifier.doi","10.1002/mrm.25921"],["dc.identifier.isi","000388617200016"],["dc.identifier.pmid","26414857"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39571"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1522-2594"],["dc.relation.issn","0740-3194"],["dc.title","A Model-Based Reconstruction Technique for Quantitative Myocardial Perfusion Imaging"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","936"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Cellular & Molecular Immunology"],["dc.bibliographiccitation.lastpage","944"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Bošnjak, Berislav"],["dc.contributor.author","Stein, Saskia Catherina"],["dc.contributor.author","Willenzon, Stefanie"],["dc.contributor.author","Cordes, Anne Katrin"],["dc.contributor.author","Puppe, Wolfram"],["dc.contributor.author","Bernhardt, Günter"],["dc.contributor.author","Ravens, Inga"],["dc.contributor.author","Ritter, Christiane"],["dc.contributor.author","Schultze-Florey, Christian R."],["dc.contributor.author","Gödecke, Nina"],["dc.contributor.author","Martens, Jörg"],["dc.contributor.author","Kleine-Weber, Hannah"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Cossmann, Anne"],["dc.contributor.author","Yilmaz, Mustafa"],["dc.contributor.author","Pink, Isabelle"],["dc.contributor.author","Hoeper, Marius M."],["dc.contributor.author","Behrens, Georg M. N."],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Blasczyk, Rainer"],["dc.contributor.author","Schulz, Thomas F."],["dc.contributor.author","Förster, Reinhold"],["dc.date.accessioned","2021-04-14T08:31:50Z"],["dc.date.available","2021-04-14T08:31:50Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1038/s41423-020-00573-9"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83727"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","2042-0226"],["dc.relation.issn","1672-7681"],["dc.title","Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","suppl_1"],["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Ritter, Christian Oliver"],["dc.contributor.author","Reupke, V."],["dc.contributor.author","Wilke, Robin Niklas"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Uecker, Martin"],["dc.date.accessioned","2020-05-13T13:45:40Z"],["dc.date.available","2020-05-13T13:45:40Z"],["dc.date.issued","2017"],["dc.description.abstract","Background: Endomyocardial biopsies (EMB) are an important diagnostic tool for myocarditis. Despite procedural success, the large sampling error results in the necessity of multiple (>6) biopsies. In cardiac magnetic resonance (CMR) imaging late gadolinium enhancement (LGE) depicts areas of affected myocardium. Thus, targeted biopsy under real-time magnetic resonance image guidance might reduce sampling error. Methods: Seven minipigs (MP) of the Goettingen strain underwent radiofrequency (RF) (2x30s, max. 30 W, temperature 60–64 °C) ablation in the left ventricle. Two focal lesions were induced (lateral wall in five apex in two animals). Biopsies were taken immediately after lesion induction using a 7 F conventional bioptome under fluoroscopic guidance (FLG) at the ablation site. Afterwards the CMR and lesion visualization by LGE was performed on a 3T MRI scanner. The lesions were biopsied under CMR-guidance using a MR-compatible bioptome (fig.1) guided by a steerable catheter. Interactive real-time visualization of the intervention was based on radial FLASH with nonlinear inverse reconstruction (NLINV) (temporal resolution 42 ms). All samples underwent a standard histological evaluation. Results: RF-ablation was successful in all MP. FL- guided biopsies were performed succesfully in 6/6 MP. Detection of RF lesions by CMR detection was successful in 7/7 MP, i.e. at least one lesion was clearly visible. Localization and tracking of the catheters and the bioptome using interactive control of the imaging plane was achieved in 6/6 MP; however in the MP with a large PE after EMB under fluoroscopy no further EMB was attempted for safety reasons. Biopsies under CMR guidance were successfully performed in 5/6 animals, in one MP the bioptome reached the lesion, however the forceps did not cut out a sample. Specimens obtained under CMR guidance contained part of the lesion in 6/15 (40%) myocardial specimens and in 4/5 (80%) animals in which samples were achieved. Conventional biopsies revealed ablation lesions in 4/17 (23.5%) specimens in 3/6 MP (50%). Conclusion: RF-induced focal lesions are a useful tool for CMR-guided biopsy studies in minipigs. In contrast to fluoroscopy, CMR provides excellent visualization of lesions. Interactive real-time MRI allows excellent passive tracking of the instruments and EMB provides significantly superior sampling accuracy compared to FL-guided biopsies. Improvements of MR-compatible bioptomes and guiding catheters are essential before applying this method in a clinical setting."],["dc.identifier.doi","10.1093/eurheartj/ehx502.P1428"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/65373"],["dc.language.iso","en"],["dc.relation.eissn","1522-9645"],["dc.relation.issn","0195-668X"],["dc.title","P1428Real time guidance for targeted endomyocardial biopsy in a minipig model"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","54"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","61"],["dc.bibliographiccitation.volume","257"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Broder, Marike"],["dc.contributor.author","Hösch, Olga"],["dc.contributor.author","Lamata, Pablo"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Ritter, Christian Oliver"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2018-04-23T11:48:00Z"],["dc.date.available","2018-04-23T11:48:00Z"],["dc.date.issued","2018"],["dc.description.abstract","Purpose We aimed to quantify atrial and ventricular myocardial deformation in Ebstein's Anomaly (EA) in a case-control study with cardiovascular magnetic resonance (CMR) feature tracking and to correlate changes in cardiac performance with the severity of disease and clinical heart failure parameters. Materials and methods Atrial and ventricular deformation was measured using CMR feature tracking in 30 EA and 20 healthy control subjects. Atrial performance was characterized using longitudinal strain and strain rate parameters for reservoir function, conduit function and booster pump function. Ventricular performance was characterized using RV and LV global longitudinal strain (εl) and LV circumferential and radial strain (εc and εr). Volumetric measurements for the ventricles including the Total Right/Left-Volume-Index (R/L-Volume-Index) and heart failure markers (BNP, NYHA class) were also quantified. Results EA patients showed significantly impaired right atrial performance, which correlated with heart failure markers (NYHA, BNP, R/L-Volume-Index). LA function in EA patients was also impaired with atrial contractile function correlating with NYHA class. EA patients exhibited impaired RV myocardial deformation, also with a significant correlation with heart failure markers. Conclusion CMR feature tracking can be used to quantify ventricular and atrial function in a complex cardiac malformation such as EA. EA is characterized by impaired quantitative right heart atrio-ventricular deformation, which is associated with heart failure severity. While LV function remains preserved, there is also significant impairment of LA function. These quantitative performance parameters may represent early markers of cardiac deterioration of potential value in the clinical management of EA."],["dc.identifier.doi","10.1016/j.ijcard.2017.11.097"],["dc.identifier.gro","3142316"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/13449"],["dc.language.iso","en"],["dc.notes.intern","lifescience updates Crossref Import"],["dc.notes.status","final"],["dc.relation.issn","0167-5273"],["dc.title","Atrio-ventricular deformation and heart failure in Ebstein's Anomaly - A cardiovascular magnetic resonance study"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]