Calapai, Antonino

[["dc.bibliographiccitation.artnumber","jn.00614.2017"],["dc.bibliographiccitation.journal","Journal of Neurophysiology"],["dc.contributor.author","Berger, Michael"],["dc.contributor.author","Calapai, Antonino"],["dc.contributor.author","Stephan, Valeska"],["dc.contributor.author","Niessing, Michael"],["dc.contributor.author","Burchardt, Leonore"],["dc.contributor.author","Gail, Alexander"],["dc.contributor.author","Treue, Stefan"],["dc.date.accessioned","2018-01-17T13:11:54Z"],["dc.date.available","2018-01-17T13:11:54Z"],["dc.date.issued","2017"],["dc.description.abstract","Teaching non-human primates the complex cognitive behavioral tasks that are central to cognitive neuroscience research is an essential and challenging endeavor. It is crucial for the scientific success that the animals learn to interpret the often complex task rules, and reliably and enduringly act accordingly. To achieve consistent behavior and comparable learning histories across animals, it is desirable to standardize training protocols. Automatizing the training can significantly reduce the time invested by the person training the animal. And self-paced training schedules with individualized learning speeds based on automatic updating of task conditions could enhance the animals' motivation and welfare. We developed a training paradigm for across-task unsupervised training (AUT) of successively more complex cognitive tasks to be administered through a stand-alone housing-based system optimized for rhesus monkeys in neuroscience research settings (Calapai et al. 2016). The AUT revealed inter-individual differences in long-term learning progress between animals, helping to characterize learning personalities, and commonalities, helping to identify easier and more difficult learning steps in the training protocol. Our results demonstrate that (1) rhesus monkeys stay engaged with the AUT over months despite access to water and food outside the experimental sessions, but with lower numbers of interaction compared to conventional fluid-controlled training; (2) with unsupervised training across sessions and task levels, rhesus monkeys can learn tasks of sufficient complexity for state-of-the art cognitive neuroscience in their housing environment; (3) AUT learning progress is primarily determined by the number of interactions with the system rather than the mere exposure time."],["dc.identifier.doi","10.1152/jn.00614.2017"],["dc.identifier.pmid","29142094"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/11705"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.relation.eissn","1522-1598"],["dc.title","Standardized automated training of rhesus monkeys for neuroscience research in their housing environment"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Xue, Cheng"],["dc.contributor.author","Calapai, Antonino"],["dc.contributor.author","Krumbiegel, Julius"],["dc.contributor.author","Treue, Stefan"],["dc.date.accessioned","2021-06-01T10:50:42Z"],["dc.date.available","2021-06-01T10:50:42Z"],["dc.date.issued","2020"],["dc.description.abstract","Abstract Small ballistic eye movements, so called microsaccades, occur even while foveating an object. Previous studies using covert attention tasks have shown that shortly after a symbolic spatial cue, specifying a behaviorally relevant location, microsaccades tend to be directed toward the cued location. This suggests that microsaccades can serve as an index for the covert orientation of spatial attention. However, this hypothesis faces two major challenges: First, effects associated with visual spatial attention are hard to distinguish from those that associated with the contemplation of foveating a peripheral stimulus. Second, it is less clear whether endogenously sustained attention alone can bias microsaccade directions without a spatial cue on each trial. To address the first issue, we investigated the direction of microsaccades in human subjects while they attended to a behaviorally relevant location and prepared a response eye movement either toward or away from this location. We find that directions of microsaccades are biased toward the attended location rather than towards the saccade target. To tackle the second issue, we verbally indicated the location to attend before the start of each block of trials, to exclude potential visual cue-specific effects on microsaccades. Our results indicate that sustained spatial attention alone reliably produces the microsaccade direction effect. Overall, our findings demonstrate that sustained spatial attention alone, even in the absence of saccade planning or a spatial cue, is sufficient to explain the direction bias observed in microsaccades."],["dc.identifier.doi","10.1038/s41598-020-77455-7"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86756"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","2045-2322"],["dc.title","Sustained spatial attention accounts for the direction bias of human microsaccades"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]