Mandad, Sunit

[["dc.bibliographiccitation.firstpage","3333"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Nature Protocols"],["dc.bibliographiccitation.lastpage","3365"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Alevra, Mihai"],["dc.contributor.author","Mandad, Sunit"],["dc.contributor.author","Ischebeck, Till"],["dc.contributor.author","Urlaub, Henning"],["dc.contributor.author","Rizzoli, Silvio O."],["dc.contributor.author","Fornasiero, Eugenio F."],["dc.date.accessioned","2020-12-10T18:10:05Z"],["dc.date.available","2020-12-10T18:10:05Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1038/s41596-019-0222-y"],["dc.identifier.pmid","31685960"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73844"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/110"],["dc.identifier.url","https://sfb1286.uni-goettingen.de/literature/publications/80"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","SFB 1286: Quantitative Synaptologie"],["dc.relation","SFB 1286 | A03: Dynamische Analyse der Remodellierung der extrazellulären Matrix (ECM) als Mechanismus der Synapsenorganisation und Plastizität"],["dc.relation.workinggroup","RG Rizzoli (Quantitative Synaptology in Space and Time)"],["dc.relation.workinggroup","RG Urlaub (Bioanalytische Massenspektrometrie)"],["dc.title","A mass spectrometry workflow for measuring protein turnover rates in vivo"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","16913"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Mandad, Sunit"],["dc.contributor.author","Rahman, Raza-Ur"],["dc.contributor.author","Centeno, Tonatiuh Pena"],["dc.contributor.author","Vidal, Ramon O."],["dc.contributor.author","Wildhagen, Hanna"],["dc.contributor.author","Rammner, Burkhard"],["dc.contributor.author","Keihani, Sarva"],["dc.contributor.author","Opazo, Felipe"],["dc.contributor.author","Urban, Inga"],["dc.contributor.author","Ischebeck, Till"],["dc.contributor.author","Kirli, Koray"],["dc.contributor.author","Benito, Eva"],["dc.contributor.author","Fischer, André"],["dc.contributor.author","Yousefi, Roya Y."],["dc.contributor.author","Dennerlein, Sven"],["dc.contributor.author","Rehling, Peter"],["dc.contributor.author","Feußner, Ivo"],["dc.contributor.author","Urlaub, Henning"],["dc.contributor.author","Bonn, Stefan"],["dc.contributor.author","Rizzoli, Silvio O."],["dc.contributor.author","Fornasiero, Eugenio F."],["dc.date.accessioned","2019-07-09T11:50:21Z"],["dc.date.available","2019-07-09T11:50:21Z"],["dc.date.issued","2018"],["dc.description.abstract","The homeostasis of the proteome depends on the tight regulation of the mRNA and protein abundances, of the translation rates, and of the protein lifetimes. Results from several studies on prokaryotes or eukaryotic cell cultures have suggested that protein homeostasis is connected to, and perhaps regulated by, the protein and the codon sequences. However, this has been little investigated for mammals in vivo. Moreover, the link between the coding sequences and one critical parameter, the protein lifetime, has remained largely unexplored, both in vivo and in vitro. We tested this in the mouse brain, and found that the percentages of amino acids and codons in the sequences could predict all of the homeostasis parameters with a precision approaching experimental measurements. A key predictive element was the wobble nucleotide. G-/C-ending codons correlated with higher protein lifetimes, protein abundances, mRNA abundances and translation rates than A-/U-ending codons. Modifying the proportions of G-/C-ending codons could tune these parameters in cell cultures, in a proof-of-principle experiment. We suggest that the coding sequences are strongly linked to protein homeostasis in vivo, albeit it still remains to be determined whether this relation is causal in nature."],["dc.identifier.doi","10.1038/s41598-018-35277-8"],["dc.identifier.pmid","30443017"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15918"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59754"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/209"],["dc.identifier.url","https://sfb1190.med.uni-goettingen.de/production/literature/publications/44"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/339580/EU//MITRAC"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/614765/EU//NEUROMOLANATOMY"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","SFB 1190: Transportmaschinen und Kontaktstellen zellulärer Kompartimente"],["dc.relation","SFB 1190 | P09: Proteinsortierung in der Synapse: Prinzipien und molekulare Organisation"],["dc.relation.issn","2045-2322"],["dc.relation.workinggroup","RG A. Fischer (Epigenetics and Systems Medicine in Neurodegenerative Diseases)"],["dc.relation.workinggroup","RG Rehling (Mitochondrial Protein Biogenesis)"],["dc.relation.workinggroup","RG Rizzoli (Quantitative Synaptology in Space and Time)"],["dc.relation.workinggroup","RG Urlaub (Bioanalytische Massenspektrometrie)"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.title","The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","eabn4437"],["dc.bibliographiccitation.issue","20"],["dc.bibliographiccitation.journal","Science Advances"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Kluever, Verena"],["dc.contributor.author","Russo, Belisa"],["dc.contributor.author","Mandad, Sunit"],["dc.contributor.author","Kumar, Nisha Hemandhar"],["dc.contributor.author","Alevra, Mihai"],["dc.contributor.author","Ori, Alessandro"],["dc.contributor.author","Rizzoli, Silvio O."],["dc.contributor.author","Urlaub, Henning"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Fornasiero, Eugenio F."],["dc.date.accessioned","2022-06-01T09:39:33Z"],["dc.date.available","2022-06-01T09:39:33Z"],["dc.date.issued","2022"],["dc.description.abstract","Aging is a prominent risk factor for neurodegenerative disorders (NDDs); however, the molecular mechanisms rendering the aged brain particularly susceptible to neurodegeneration remain unclear. Here, we aim to determine the link between physiological aging and NDDs by exploring protein turnover using metabolic labeling and quantitative pulse-SILAC proteomics. By comparing protein lifetimes between physiologically aged and young adult mice, we found that in aged brains protein lifetimes are increased by ~20% and that aging affects distinct pathways linked to NDDs. Specifically, a set of neuroprotective proteins are longer-lived in aged brains, while some mitochondrial proteins linked to neurodegeneration are shorter-lived. Strikingly, we observed a previously unknown alteration in proteostasis that correlates to parsimonious turnover of proteins with high biosynthetic costs, revealing an overall metabolic adaptation that preludes neurodegeneration. Our findings suggest that future therapeutic paradigms, aimed at addressing these metabolic adaptations, might be able to delay NDD onset."],["dc.description.abstract","Physiological brain aging affects protein turnover, altering the stability of proteins linked to neurodegenerative diseases."],["dc.identifier.doi","10.1126/sciadv.abn4437"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108506"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.eissn","2375-2548"],["dc.title","Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","4230"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Nature Communications"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Fornasiero, Eugenio F."],["dc.contributor.author","Mandad, Sunit"],["dc.contributor.author","Wildhagen, Hanna"],["dc.contributor.author","Alevra, Mihai"],["dc.contributor.author","Rammner, Burkhard"],["dc.contributor.author","Keihani, Sarva"],["dc.contributor.author","Opazo, Felipe"],["dc.contributor.author","Urban, Inga"],["dc.contributor.author","Ischebeck, Till"],["dc.contributor.author","Sakib, M. Sadman"],["dc.contributor.author","Fard, Maryam K."],["dc.contributor.author","Kirli, Koray"],["dc.contributor.author","Centeno, Tonatiuh Pena"],["dc.contributor.author","Vidal, Ramon O."],["dc.contributor.author","Rahman, Raza-Ur"],["dc.contributor.author","Benito, Eva"],["dc.contributor.author","Fischer, André"],["dc.contributor.author","Dennerlein, Sven"],["dc.contributor.author","Rehling, Peter"],["dc.contributor.author","Feussner, Ivo"],["dc.contributor.author","Bonn, Stefan"],["dc.contributor.author","Simons, Mikael"],["dc.contributor.author","Urlaub, Henning"],["dc.contributor.author","Rizzoli, Silvio O."],["dc.date.accessioned","2019-07-09T11:46:03Z"],["dc.date.available","2019-07-09T11:46:03Z"],["dc.date.issued","2018"],["dc.description.abstract","The turnover of brain proteins is critical for organism survival, and its perturbations are linked to pathology. Nevertheless, protein lifetimes have been difficult to obtain in vivo. They are readily measured in vitro by feeding cells with isotopically labeled amino acids, followed by mass spectrometry analyses. In vivo proteins are generated from at least two sources: labeled amino acids from the diet, and non-labeled amino acids from the degradation of pre-existing proteins. This renders measurements difficult. Here we solved this problem rigorously with a workflow that combines mouse in vivo isotopic labeling, mass spectrometry, and mathematical modeling. We also established several independent approaches to test and validate the results. This enabled us to measure the accurate lifetimes of ~3500 brain proteins. The high precision of our data provided a large set of biologically significant observations, including pathway-, organelle-, organ-, or cell-specific effects, along with a comprehensive catalog of extremely long-lived proteins (ELLPs)."],["dc.identifier.doi","10.1038/s41467-018-06519-0"],["dc.identifier.pmid","30315172"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15388"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59372"],["dc.identifier.url","https://sfb1190.med.uni-goettingen.de/production/literature/publications/42"],["dc.identifier.url","https://sfb1286.uni-goettingen.de/literature/publications/41"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.intern","In goescholar not merged with http://resolver.sub.uni-goettingen.de/purl?gs-1/15611 but duplicate"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/339580/EU//MITRAC"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/614765/EU//NEUROMOLANATOMY"],["dc.relation","SFB 1190: Transportmaschinen und Kontaktstellen zellulärer Kompartimente"],["dc.relation","SFB 1190 | P09: Proteinsortierung in der Synapse: Prinzipien und molekulare Organisation"],["dc.relation","SFB 1286: Quantitative Synaptologie"],["dc.relation","SFB 1286 | A03: Dynamische Analyse der Remodellierung der extrazellulären Matrix (ECM) als Mechanismus der Synapsenorganisation und Plastizität"],["dc.relation.issn","2041-1723"],["dc.relation.workinggroup","RG Rehling (Mitochondrial Protein Biogenesis)"],["dc.relation.workinggroup","RG Rizzoli (Quantitative Synaptology in Space and Time)"],["dc.relation.workinggroup","RG Urlaub (Bioanalytische Massenspektrometrie)"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","573"],["dc.subject.ddc","612"],["dc.title","Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The EMBO Journal"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Mariappan, Aruljothi"],["dc.contributor.author","Soni, Komal"],["dc.contributor.author","Schorpp, Kenji"],["dc.contributor.author","Zhao, Fan"],["dc.contributor.author","Minakar, Amin"],["dc.contributor.author","Zheng, Xiangdong"],["dc.contributor.author","Mandad, Sunit"],["dc.contributor.author","Macheleidt, Iris"],["dc.contributor.author","Ramani, Anand"],["dc.contributor.author","Kubelka, Tomáš"],["dc.contributor.author","Dawidowski, Maciej"],["dc.contributor.author","Golfmann, Kristina"],["dc.contributor.author","Wason, Arpit"],["dc.contributor.author","Yang, Chunhua"],["dc.contributor.author","Simons, Judith"],["dc.contributor.author","Schmalz, Hans‐Günther"],["dc.contributor.author","Hyman, Anthony A"],["dc.contributor.author","Aneja, Ritu"],["dc.contributor.author","Ullrich, Roland"],["dc.contributor.author","Urlaub, Henning"],["dc.contributor.author","Odenthal, Margarete"],["dc.contributor.author","Büttner, Reinhardt"],["dc.contributor.author","Li, Haitao"],["dc.contributor.author","Sattler, Michael"],["dc.contributor.author","Hadian, Kamyar"],["dc.contributor.author","Gopalakrishnan, Jay"],["dc.date.accessioned","2020-12-10T18:42:37Z"],["dc.date.available","2020-12-10T18:42:37Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.15252/embj.201899876"],["dc.identifier.eissn","1460-2075"],["dc.identifier.issn","0261-4189"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78027"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Inhibition of CPAP –tubulin interaction prevents proliferation of centrosome‐amplified cancer cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3618"],["dc.bibliographiccitation.issue","13"],["dc.bibliographiccitation.journal","Cell Reports"],["dc.bibliographiccitation.lastpage","3630.e6"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Ramani, Anand"],["dc.contributor.author","Mariappan, Aruljothi"],["dc.contributor.author","Gottardo, Marco"],["dc.contributor.author","Mandad, Sunit"],["dc.contributor.author","Urlaub, Henning"],["dc.contributor.author","Avidor-Reiss, Tomer"],["dc.contributor.author","Riparbelli, Maria"],["dc.contributor.author","Callaini, Giuliano"],["dc.contributor.author","Debec, Alain"],["dc.contributor.author","Feederle, Regina"],["dc.contributor.author","Gopalakrishnan, Jay"],["dc.date.accessioned","2020-12-10T14:23:01Z"],["dc.date.available","2020-12-10T14:23:01Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.celrep.2018.11.102"],["dc.identifier.issn","2211-1247"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71805"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","eaam7816"],["dc.bibliographiccitation.issue","419"],["dc.bibliographiccitation.journal","Science Translational Medicine"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Fard, Maryam K."],["dc.contributor.author","van der Meer, Franziska"],["dc.contributor.author","Sánchez, Paula"],["dc.contributor.author","Cantuti-Castelvetri, Ludovico"],["dc.contributor.author","Mandad, Sunit"],["dc.contributor.author","Jäkel, Sarah"],["dc.contributor.author","Fornasiero, Eugenio F."],["dc.contributor.author","Schmitt, Sebastian"],["dc.contributor.author","Ehrlich, Marc"],["dc.contributor.author","Starost, Laura"],["dc.contributor.author","Kuhlmann, Tanja"],["dc.contributor.author","Sergiou, Christina"],["dc.contributor.author","Schultz, Verena"],["dc.contributor.author","Wrzos, Claudia"],["dc.contributor.author","Brück, Wolfgang"],["dc.contributor.author","Urlaub, Henning"],["dc.contributor.author","Dimou, Leda"],["dc.contributor.author","Stadelmann, Christine"],["dc.contributor.author","Simons, Mikael"],["dc.date.accessioned","2020-12-10T18:36:46Z"],["dc.date.available","2020-12-10T18:36:46Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1126/scitranslmed.aam7816"],["dc.identifier.eissn","1946-6242"],["dc.identifier.issn","1946-6234"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76735"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1023"],["dc.bibliographiccitation.issue","6187"],["dc.bibliographiccitation.journal","Science"],["dc.bibliographiccitation.lastpage","1028"],["dc.bibliographiccitation.volume","344"],["dc.contributor.author","Wilhelm, Benjamin G."],["dc.contributor.author","Mandad, Sunit"],["dc.contributor.author","Truckenbrodt, Sven"],["dc.contributor.author","Kroehnert, Katharina"],["dc.contributor.author","Schaefer, Christina"],["dc.contributor.author","Rammner, Burkhard"],["dc.contributor.author","Koo, Seong Joo"],["dc.contributor.author","Classen, Gala A."],["dc.contributor.author","Krauss, Michael"],["dc.contributor.author","Haucke, Volker"],["dc.contributor.author","Urlaub, Henning"],["dc.contributor.author","Rizzoli, S. O."],["dc.date.accessioned","2017-09-07T11:46:14Z"],["dc.date.available","2017-09-07T11:46:14Z"],["dc.date.issued","2014"],["dc.description.abstract","Synaptic vesicle recycling has long served as a model for the general mechanisms of cellular trafficking. We used an integrative approach, combining quantitative immunoblotting and mass spectrometry to determine protein numbers; electron microscopy to measure organelle numbers, sizes, and positions; and super-resolution fluorescence microscopy to localize the proteins. Using these data, we generated a three-dimensional model of an \"average\" synapse, displaying 300,000 proteins in atomic detail. The copy numbers of proteins involved in the same step of synaptic vesicle recycling correlated closely. In contrast, copy numbers varied over more than three orders of magnitude between steps, from about 150 copies for the endosomal fusion proteins to more than 20,000 for the exocytotic ones."],["dc.identifier.doi","10.1126/science.1252884"],["dc.identifier.gro","3142118"],["dc.identifier.isi","000336495800044"],["dc.identifier.pmid","24876496"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/4744"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.eissn","1095-9203"],["dc.relation.issn","0036-8075"],["dc.title","Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1151"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Nature Neuroscience"],["dc.bibliographiccitation.lastpage","1162"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Helm, Martin S."],["dc.contributor.author","Dankovich, Tal M."],["dc.contributor.author","Mandad, Sunit"],["dc.contributor.author","Rammner, Burkhard"],["dc.contributor.author","Jähne, Sebastian"],["dc.contributor.author","Salimi, Vanessa"],["dc.contributor.author","Koerbs, Christina"],["dc.contributor.author","Leibrandt, Richard"],["dc.contributor.author","Urlaub, Henning"],["dc.contributor.author","Rizzoli, Silvio O."],["dc.date.accessioned","2021-08-12T07:44:59Z"],["dc.date.available","2021-08-12T07:44:59Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1038/s41593-021-00874-w"],["dc.identifier.pii","874"],["dc.identifier.pmid","34168338"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88345"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/312"],["dc.identifier.url","https://sfb1190.med.uni-goettingen.de/production/literature/publications/148"],["dc.identifier.url","https://sfb1286.uni-goettingen.de/literature/publications/125"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-448"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","SFB 1190: Transportmaschinen und Kontaktstellen zellulärer Kompartimente"],["dc.relation","SFB 1190 | P09: Proteinsortierung in der Synapse: Prinzipien und molekulare Organisation"],["dc.relation","SFB 1286: Quantitative Synaptologie"],["dc.relation","SFB 1286 | A03: Dynamische Analyse der Remodellierung der extrazellulären Matrix (ECM) als Mechanismus der Synapsenorganisation und Plastizität"],["dc.relation","SFB 1286 | A08: Die Rolle post-translational modifizierter Proteine in der synaptischen Übertragung"],["dc.relation.eissn","1546-1726"],["dc.relation.issn","1097-6256"],["dc.relation.workinggroup","RG Rizzoli (Quantitative Synaptology in Space and Time)"],["dc.relation.workinggroup","RG Urlaub (Bioanalytische Massenspektrometrie)"],["dc.title","A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","eaay2670"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Science Advances"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Keihani, S."],["dc.contributor.author","Kluever, V."],["dc.contributor.author","Mandad, S."],["dc.contributor.author","Bansal, V."],["dc.contributor.author","Rahman, R."],["dc.contributor.author","Fritsch, E."],["dc.contributor.author","Gomes, L. Caldi"],["dc.contributor.author","Gärtner, A."],["dc.contributor.author","Kügler, S."],["dc.contributor.author","Urlaub, H."],["dc.contributor.author","Wren, J. D."],["dc.contributor.author","Bonn, S."],["dc.contributor.author","Rizzoli, S. O."],["dc.contributor.author","Fornasiero, E. F."],["dc.date.accessioned","2020-12-10T18:36:40Z"],["dc.date.available","2020-12-10T18:36:40Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1126/sciadv.aay2670"],["dc.identifier.pmid","31897430"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17142"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76705"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/198"],["dc.identifier.url","https://sfb1286.uni-goettingen.de/literature/publications/46"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation","SFB 1286: Quantitative Synaptologie"],["dc.relation","SFB 1286 | A06: Mitochondrienfunktion und -umsatz in Synapsen"],["dc.relation","SFB 1286 | B02: Ein in vitro-Verfahren zum Verständnis der struktur-organisierenden Rolle des Vesikel-Clusters"],["dc.relation","SFB 1286 | Z02: Integrative Datenanalyse und -interpretation. Generierung einer synaptisch-integrativen Datenstrategie (SynIDs)"],["dc.relation.workinggroup","RG Rizzoli (Quantitative Synaptology in Space and Time)"],["dc.relation.workinggroup","RG Bonn"],["dc.relation.workinggroup","RG Urlaub (Bioanalytische Massenspektrometrie)"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.title","The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]