Schnieder, Marlena

[["dc.bibliographiccitation.artnumber","e0216258"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","PLOS ONE"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.contributor.author","Tsogkas, Ioannis"],["dc.contributor.author","Brehm, Alex"],["dc.contributor.author","Hesse, Amelie"],["dc.contributor.author","McTaggart, Ryan"],["dc.contributor.author","Goyal, Mayank"],["dc.contributor.author","Maier, Ilko"],["dc.contributor.author","Schnieder, Marlena"],["dc.contributor.author","Behme, Daniel"],["dc.contributor.author","Maus, Volker"],["dc.date.accessioned","2019-07-09T11:51:31Z"],["dc.date.available","2019-07-09T11:51:31Z"],["dc.date.issued","2019"],["dc.description.abstract","INTRODUCTION: The \"Stent retriever Assisted Vacuum-locked Extraction\" (SAVE) technique is a promising embolectomy method for intracranial large vessel occlusion (LVO). We report our experience using a modified SAVE (mSAVE) approach for clot reduction prior to embolectomy in acute ischemic stroke patients with large clots. MATERIALS AND METHODS: We retrospectively analyzed 20 consecutive patients undergoing mSAVE in our center due to intracranial LVO. Angiographic data (including first-pass and overall complete reperfusion, defined as an expanded Thrombolysis in Cerebral Infarction (eTICI) score of 3, rate of successful reperfusion (eTICI ≥2c), number of passes, time from groin puncture to reperfusion) and clinical data (favorable outcome at 90 days, defined as modified Rankin Scale (mRS) ≤2) were assessed. RESULTS: First-pass and overall eTICI 3 reperfusion was reached in 13/20 (65%) and 14/20 (70%), respectively. The rate of successful reperfusion (eTICI ≥2c) after one pass was 85% and on final angiogram 90% with an average number of 1.1 ± 0.3 attempts. Eight out of 11 (73%) ICA occlusions were reperfused successfully and 5 (46%) completely after a single pass. Median groin to reperfusion time was 33 minutes (IQR 25-46). A favorable clinical outcome was achieved in 9/20 (45%) patients at discharge and after 90 days, respectively. CONCLUSION: Clot reduction followed by embolectomy (mSAVE) is feasible and may be an important tool in the treatment of large clots."],["dc.identifier.doi","10.1371/journal.pone.0216258"],["dc.identifier.pmid","31071109"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16142"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59962"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.title","Clot reduction prior to embolectomy: mSAVE as a first-line technique for large clots"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]