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Poustka, Luise
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Poustka, Luise
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Poustka, Luise
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Poustka, L.
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2016Journal Article [["dc.bibliographiccitation.firstpage","489"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Public Health"],["dc.bibliographiccitation.lastpage","495"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Parchetka, Caroline"],["dc.contributor.author","Strache, Nicole"],["dc.contributor.author","Raffaelli, Bianca"],["dc.contributor.author","Gemmeke, Isabel"],["dc.contributor.author","Weiß, Katharina"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Buechel, Christian"],["dc.contributor.author","Conrod, Patricia"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Lemaitre, Herve"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Mennigen, Eva"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Paillère Martinot, Marie-Laure"],["dc.contributor.author","Papadopoulos, Dimitri"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Jurk, Sarah"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Vetter, Nora C."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Gallinat, Juergen"],["dc.date.accessioned","2018-06-04T09:18:35Z"],["dc.date.available","2018-06-04T09:18:35Z"],["dc.date.issued","2016"],["dc.description.abstract","Purpose The onset of substance use mostly occurs during adolescence. The aim of the present study is to investigate the relevance of personality on the basis of the NEO-Five-Factor Inventory (NEO-FFI) to future experiences with tobacco, alcohol and cannabis. Methods The test data were derived from the baseline assessment and first follow-up of the IMAGEN study, a European multicenter and multidisciplinary research project on adolescent mental health. In the present study 1004 participants were tested. The characterization of personality was conducted with the NEO-FFI at the age of 14 (T1). The data on substance use were collected with the European School Survey Project on Alcohol and Other Drugs (ESPAD) questionnaire at the age of 16 (T2). For the statistical analysis, t-tests and univariate analyses of variance were performed. Results The scores of Conscientiousness at T1 were significantly lower for adolescents with tobacco, alcohol and cannabis experiences at T2. We found lower scores of Agreeableness at T1 in participants with tobacco and cannabis use at T2. Extraversion at T1 was significantly higher for adolescents with smoking experiences at T2. No significant associations between Neuroticism or Openness and future substance use were observed. Conclusion Low scores of Conscientiousness and Agreeableness seem to have the greatest value for a prediction of later experiences with substance use. As the present study is the first one to examine the predictive value of the NEO-FFI for future substance use in an adolescent sample, further studies are necessary to enable a better applicability in a clinical context."],["dc.identifier.doi","10.1007/s10389-016-0747-2"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/14854"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.title","Predictive utility of the NEO-FFI for later substance experiences among 16-year-old adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]Details DOI2019Journal Article [["dc.bibliographiccitation.firstpage","1680"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Autism Research"],["dc.bibliographiccitation.lastpage","1692"],["dc.bibliographiccitation.volume","12"],["dc.contributor.affiliation","Banaschewski, Tobias; 2\r\nDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim\r\nHeidelberg University\r\nMannheim Germany"],["dc.contributor.affiliation","Dziobek, Isabel; 3\r\nBerlin School of Mind and Brain and Institute of Psychology\r\nHumboldt‐Universität zu Berlin\r\nBerlin Germany"],["dc.contributor.affiliation","Brandeis, Daniel; 2\r\nDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim\r\nHeidelberg University\r\nMannheim Germany"],["dc.contributor.affiliation","Poustka, Luise; 2\r\nDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim\r\nHeidelberg University\r\nMannheim Germany"],["dc.contributor.affiliation","Freitag, Christine M.; 1\r\nDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy\r\nUniversity Hospital, Goethe University Frankfurt am Main\r\nFrankfurt Germany"],["dc.contributor.author","Bast, Nico"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Dziobek, Isabel"],["dc.contributor.author","Brandeis, Daniel"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Freitag, Christine M."],["dc.date.accessioned","2019-11-25T15:27:33Z"],["dc.date.accessioned","2021-10-27T13:21:35Z"],["dc.date.available","2019-11-25T15:27:33Z"],["dc.date.available","2021-10-27T13:21:35Z"],["dc.date.issued","2019"],["dc.date.updated","2022-02-09T13:22:08Z"],["dc.description.abstract","Progression of pupil dilation (PD) in response to visual stimuli may indicate distinct internal processes. No study has been performed on PD progression during a social cognition task. Here, we describe PD progression during the Movie for the Assessment of Social Cognition (MASC) test in n = 23 adolescents with Autism Spectrum Disorder (ASD) and n = 24 age, IQ and sex-matched neurotypical controls (NTC). The MASC consists of 43 video sequences depicting human social interactions, each followed by a multiple-choice question concerning characters' mental states. PD progression data were extracted by eye tracking and controlled for fixation behavior. Segmenting PD progression during video sequences by principal component analysis, three sequential PD components were unveiled. In ASD compared with NTC, a distinct PD progression was observed with increased constriction amplitude, increased dilation latency, and increased dilation amplitude that correlated with PD progression components. These components predicted social cognition performance. The first and second PD components correlated positively with MASC behavioral performance in ASD but negatively in NTC. These PD components may be interpreted as indicators of sensory-perceptual processing and attention function. In ASD, aberrant sensory-perceptual processing and attention function could contribute to attenuated social cognition performance. This needs to be tested by additional studies combining the respective cognitive tests and the outlined PD progression analysis. Phasic activity of the locus coeruleus-norepinephrine system is discussed as putatively shared underlying mechanism. Autism Res2019. © 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: In adolescents with autism, we found an altered pupil dilation during watching scenes of human interactions. Early pupil dilation correlated positively with the number of correct answers to questions about the shown human interactions. Our findings suggest that aberrant sensory processing and attention function may contribute to altered social cognition in autism."],["dc.description.sponsorship","Innovative Medicines Initiative Joint Undertaking"],["dc.identifier.doi","10.1002/aur.2178"],["dc.identifier.eissn","1939-3806"],["dc.identifier.issn","1939-3792"],["dc.identifier.pmid","31347301"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16726"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92033"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.publisher","John Wiley & Sons, Inc."],["dc.relation.eissn","1939-3806"],["dc.relation.issn","1939-3806"],["dc.relation.issn","1939-3792"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.title","Pupil Dilation Progression Modulates Aberrant Social Cognition in Autism Spectrum Disorder"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC2015Journal Article Research Paper [["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","O'Leary-Barrett, M."],["dc.contributor.author","Pihl, Robert O."],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Buchel, Christian"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Mann, Karl"],["dc.contributor.author","Paillere-Martinot, Marie-Laure"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Paus, Tomas"],["dc.contributor.author","Pausova, Zdenka"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Rietschel, Marcella"],["dc.contributor.author","Robbins, Trevor W."],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Strohle, Andreas"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Conrod, Patricia J."],["dc.date.accessioned","2017-09-07T11:52:11Z"],["dc.date.available","2017-09-07T11:52:11Z"],["dc.date.issued","2015"],["dc.description.abstract","OBJECTIVE: To investigate the role of personality factors and attentional biases towards emotional faces, in establishing concurrent and prospective risk for mental disorder diagnosis in adolescence.; METHOD: Data were obtained as part of the IMAGEN study, conducted across 8 European sites, with a community sample of 2257 adolescents. At 14 years, participants completed an emotional variant of the dot-probe task, as well two personality measures, namely the Substance Use Risk Profile Scale and the revised NEO Personality Inventory. At 14 and 16 years, participants and their parents were interviewed to determine symptoms of mental disorders.; RESULTS: Personality traits were general and specific risk indicators for mental disorders at 14 years. Increased specificity was obtained when investigating the likelihood of mental disorders over a 2-year period, with the Substance Use Risk Profile Scale showing incremental validity over the NEO Personality Inventory. Attentional biases to emotional faces did not characterise or predict mental disorders examined in the current sample.; DISCUSSION: Personality traits can indicate concurrent and prospective risk for mental disorders in a community youth sample, and identify at-risk youth beyond the impact of baseline symptoms. This study does not support the hypothesis that attentional biases mediate the relationship between personality and psychopathology in a community sample. Task and sample characteristics that contribute to differing results among studies are discussed."],["dc.identifier.doi","10.1371/journal.pone.0128271"],["dc.identifier.gro","3151225"],["dc.identifier.pmid","26046352"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8005"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1932-6203"],["dc.title","Personality, Attentional Biases towards Emotional Faces and Symptoms of Mental Disorders in an Adolescent Sample"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]Details DOI PMID PMC2019Journal Article [["dc.bibliographiccitation.firstpage","435"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","JAMA Psychiatry"],["dc.bibliographiccitation.volume","76"],["dc.contributor.author","Luo, Qiang"],["dc.contributor.author","Chen, Qiang"],["dc.contributor.author","Wang, Wenjia"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Macare, Christine"],["dc.contributor.author","Robert, Gabriel H."],["dc.contributor.author","Cui, Jing"],["dc.contributor.author","Guedj, Mickaël"],["dc.contributor.author","Palaniyappan, Lena"],["dc.contributor.author","Kherif, Ferath"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Paillère-Martinot, Marie-Laure"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Callicott, Joseph H."],["dc.contributor.author","Mattay, Venkata S."],["dc.contributor.author","Pausova, Zdenka"],["dc.contributor.author","Dartigues, Jean-François"],["dc.contributor.author","Tzourio, Christophe"],["dc.contributor.author","Crivello, Fabrice"],["dc.contributor.author","Berman, Karen F."],["dc.contributor.author","Li, Fei"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Weinberger, Daniel R."],["dc.contributor.author","Murray, Robin M."],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Feng, Jianfeng"],["dc.date.accessioned","2019-07-09T11:51:24Z"],["dc.date.available","2019-07-09T11:51:24Z"],["dc.date.issued","2019"],["dc.description.abstract","Importance: Deviation from normal adolescent brain development precedes manifestations of many major psychiatric symptoms. Such altered developmental trajectories in adolescents may be linked to genetic risk for psychopathology. Objective: To identify genetic variants associated with adolescent brain structure and explore psychopathologic relevance of such associations. Design, Setting, and Participants: Voxelwise genome-wide association study in a cohort of healthy adolescents aged 14 years and validation of the findings using 4 independent samples across the life span with allele-specific expression analysis of top hits. Group comparison of the identified gene-brain association among patients with schizophrenia, unaffected siblings, and healthy control individuals. This was a population-based, multicenter study combined with a clinical sample that included participants from the IMAGEN cohort, Saguenay Youth Study, Three-City Study, and Lieber Institute for Brain Development sample cohorts and UK biobank who were assessed for both brain imaging and genetic sequencing. Clinical samples included patients with schizophrenia and unaffected siblings of patients from the Lieber Institute for Brain Development study. Data were analyzed between October 2015 and April 2018. Main Outcomes and Measures: Gray matter volume was assessed by neuroimaging and genetic variants were genotyped by Illumina BeadChip. Results: The discovery sample included 1721 adolescents (873 girls [50.7%]), with a mean (SD) age of 14.44 (0.41) years. The replication samples consisted of 8690 healthy adults (4497 women [51.8%]) from 4 independent studies across the life span. A nonsynonymous genetic variant (minor T allele of rs13107325 in SLC39A8, a gene implicated in schizophrenia) was associated with greater gray matter volume of the putamen (variance explained of 4.21% in the left hemisphere; 8.66; 95% CI, 6.59-10.81; P = 5.35 × 10-18; and 4.44% in the right hemisphere; t = 8.90; 95% CI, 6.75-11.19; P = 6.80 × 10-19) and also with a lower gene expression of SLC39A8 specifically in the putamen (t127 = -3.87; P = 1.70 × 10-4). The identified association was validated in samples across the life span but was significantly weakened in both patients with schizophrenia (z = -3.05; P = .002; n = 157) and unaffected siblings (z = -2.08; P = .04; n = 149). Conclusions and Relevance: Our results show that a missense mutation in gene SLC39A8 is associated with larger gray matter volume in the putamen and that this association is significantly weakened in schizophrenia. These results may suggest a role for aberrant ion transport in the etiology of psychosis and provide a target for preemptive developmental interventions aimed at restoring the functional effect of this mutation."],["dc.identifier.doi","10.1001/jamapsychiatry.2018.4126"],["dc.identifier.pmid","30649180"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16122"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59943"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation","info:eu-repo/grantAgreement/EC/H2020/720270/EU//HBP SGA1"],["dc.relation","info:eu-repo/grantAgreement/EC/H2020/695313/EU//STRATIFY"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/602450/EU//IMAGEMEND"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/603016/EU//MATRICS"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC2014Review [["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Restorative neurology and neuroscience"],["dc.bibliographiccitation.volume","32"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Brandeis, Daniel"],["dc.contributor.author","Hohmann, Sarah"],["dc.contributor.author","Holtmann, Martin"],["dc.contributor.author","Bolte, Sven"],["dc.contributor.author","Banaschewski, Tobias"],["dc.date.accessioned","2017-09-07T11:46:56Z"],["dc.date.available","2017-09-07T11:46:56Z"],["dc.date.issued","2014"],["dc.description.abstract","Autism spectrum disorders (ASD) are heterogeneous, neurodevelopmental disorders with early onset, characterized by a triad of impairments in reciprocal interaction and communication as well as repetitive and restricted interests and activities. Though underlying causes still remain largely unknown, there is now evidence for abnormal growth trajectories in the early brain development in ASD during vulnerable periods and subsequent impairment of neuronal organization and differentiation of neuronal networks. A growing number of studies over the last 10 years support the efficacy of behaviorally based interventions in ASD for the improvement of social communication and behavioral functioning. In contrast, research on neurobiologically based therapies for ASD is still at its beginnings. In this article, we will provide a selective overview of novel interventions and trainings based on neurobiological principles. Directions and options for future research on treatment aiming at restoration of normal plasticity in disrupted brain circuits in ASD are discussed."],["dc.identifier.doi","10.3233/RNN-139010"],["dc.identifier.gro","3151962"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8802"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1878-3627"],["dc.title","Neurobiologically based interventions for autism spectrum disorders-rationale and new directions"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]Details DOI2021Journal Article [["dc.bibliographiccitation.firstpage","214"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Brain Sciences"],["dc.bibliographiccitation.volume","11"],["dc.contributor.affiliation","Kaiser, Anna; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, 68159 Mannheim, Germany, anna.kaiser@zi-mannheim.de"],["dc.contributor.affiliation","Aggensteiner, Pascal-M.; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, 68159 Mannheim, Germany, Pascal.Aggensteiner@zi-mannheim.de"],["dc.contributor.affiliation","Holtmann, Martin; \t\t \r\n\t\t LWL-University Hospital for Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, Ruhr University Bochum, 59071 Hamm, Germany, martin.holtmann@lwl.org"],["dc.contributor.affiliation","Fallgatter, Andreas; \t\t \r\n\t\t Tübingen University Hospital for Psychiatry and Psychotherapy, 72076 Tübingen, Germany, Andreas.Fallgatter@med.uni-tuebingen.de"],["dc.contributor.affiliation","Romanos, Marcel; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, 97080 Würzburg, Germany, Romanos_M@ukw.de"],["dc.contributor.affiliation","Abenova, Karina; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, 68159 Mannheim, Germany, Karina.Abenova@zi-mannheim.de"],["dc.contributor.affiliation","Alm, Barbara; \t\t \r\n\t\t Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, 68159 Mannheim, Germany, Barbara.Alm@zi-mannheim.de"],["dc.contributor.affiliation","Becker, Katja; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Medical Faculty Philipps-University Marburg and University Hospital Marburg, 35039 Marburg, Germany, katja.becker@med.uni-marburg.de\t\t \r\n\t\t Center for Mind, Brain and Behavior (CMBB), University of Marburg and Justus Liebig University Giessen, 35032 Marburg, Germany, katja.becker@med.uni-marburg.de"],["dc.contributor.affiliation","Döpfner, Manfred; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany, manfred.doepfner@uk-koeln.de"],["dc.contributor.affiliation","Ethofer, Thomas; \t\t \r\n\t\t Tübingen University Hospital for Psychiatry and Psychotherapy, 72076 Tübingen, Germany, Thomas.Ethofer@med.uni-tuebingen.de"],["dc.contributor.affiliation","Freitag, Christine; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Frankfurt, Goethe University, 60323 Frankfurt am Main, Germany, C.Freitag@em.uni-frankfurt.de"],["dc.contributor.affiliation","Geissler, Julia; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, 97080 Würzburg, Germany, Geissler_J@ukw.de"],["dc.contributor.affiliation","Hebebrand, Johannes; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany, johannes.hebebrand@lvr.de"],["dc.contributor.affiliation","Huss, Michael; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany, m.huss@rfk.landeskrankenhaus.de"],["dc.contributor.affiliation","Jans, Thomas; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, 97080 Würzburg, Germany, Jans_T@ukw.de"],["dc.contributor.affiliation","Jendreizik, Lea; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany, lea.jendreizik@uk-koeln.de"],["dc.contributor.affiliation","Ketter, Johanna; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Medical Faculty Philipps-University Marburg and University Hospital Marburg, 35039 Marburg, Germany, ketterj@med.uni-marburg.de"],["dc.contributor.affiliation","Legenbauer, Tanja; \t\t \r\n\t\t LWL-University Hospital for Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, Ruhr University Bochum, 59071 Hamm, Germany, tanja.legenbauer@lwl.org"],["dc.contributor.affiliation","Philipsen, Alexandra; \t\t \r\n\t\t Department of Psychiatry and Psychotherapy, University of Bonn, 53127 Bonn, Germany, Alexandra.Philipsen@ukbonn.de"],["dc.contributor.affiliation","Poustka, Luise; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Centre Göttingen, 37075 Göttingen, Germany, luise.poustka@med.uni-goettingen.de"],["dc.contributor.affiliation","Renner, Tobias; \t\t \r\n\t\t Department of Child and Adolescence Psychiatry and Psychotherapy, University of Tübingen, 72076 Tübingen, Germany, tobias.renner@med.uni-tuebingen.de"],["dc.contributor.affiliation","Retz, Wolfgang; \t\t \r\n\t\t Department of Psychiatry and Psychotherapy, University Medical Center Mainz, 55131 Mainz, Germany, wolfgang.retz@unimedizin-mainz.de\t\t \r\n\t\t Institute for Forensic Psychology and Psychiatry, Saarland University, 66424 Homburg, Germany, wolfgang.retz@unimedizin-mainz.de"],["dc.contributor.affiliation","Rösler, Michael; \t\t \r\n\t\t Institute for Forensic Psychology and Psychiatry, Saarland University, 66424 Homburg, Germany, Michael.Roesler@uks.eu"],["dc.contributor.affiliation","Thome, Johannes; \t\t \r\n\t\t Department of Psychiatry and Psychotherapy, University Medical Center Rostock, 18055 Rostock, Germany, johannes.thome@med.uni-rostock.de"],["dc.contributor.affiliation","Uebel-von Sandersleben, Henrik; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Centre Göttingen, 37075 Göttingen, Germany, huebel@gwdg.de"],["dc.contributor.affiliation","von Wirth, Elena; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany, elena.von-wirth@uk-koeln.de"],["dc.contributor.affiliation","Zinnow, Toivo; \t\t \r\n\t\t Institute for Forensic Psychology and Psychiatry, Saarland University, 66424 Homburg, Germany, Toivo.Zinnow@uks.eu"],["dc.contributor.affiliation","Hohmann, Sarah; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, 68159 Mannheim, Germany, Sarah.Hohmann@zi-mannheim.de"],["dc.contributor.affiliation","Millenet, Sabina; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, 68159 Mannheim, Germany, Sabina.Millenet@zi-mannheim.de"],["dc.contributor.affiliation","Holz, Nathalie; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, 68159 Mannheim, Germany, Nathalie.Holz@zi-mannheim.de"],["dc.contributor.affiliation","Banaschewski, Tobias; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, 68159 Mannheim, Germany, tobias.banaschewski@zi-mannheim.de"],["dc.contributor.affiliation","Brandeis, Daniel; \t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, 68159 Mannheim, Germany, Daniel.Brandeis@zi-mannheim.de\t\t \r\n\t\t Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry, University of Zürich, 8032 Zürich, Switzerland, Daniel.Brandeis@zi-mannheim.de\t\t \r\n\t\t Center for Integrative Human Physiology, University of Zürich, 8057 Zürich, Switzerland, Daniel.Brandeis@zi-mannheim.de\t\t \r\n\t\t Neuroscience Center Zürich, Swiss Federal Institute of Technology and University of Zürich, 8057 Zürich, Switzerland, Daniel.Brandeis@zi-mannheim.de"],["dc.contributor.author","Kaiser, Anna"],["dc.contributor.author","Aggensteiner, Pascal-M."],["dc.contributor.author","Holtmann, Martin"],["dc.contributor.author","Fallgatter, Andreas"],["dc.contributor.author","Romanos, Marcel"],["dc.contributor.author","Abenova, Karina"],["dc.contributor.author","Alm, Barbara"],["dc.contributor.author","Becker, Katja"],["dc.contributor.author","Döpfner, Manfred"],["dc.contributor.author","Ethofer, Thomas"],["dc.contributor.author","Freitag, Christine"],["dc.contributor.author","Geissler, Julia"],["dc.contributor.author","Hebebrand, Johannes"],["dc.contributor.author","Huss, Michael"],["dc.contributor.author","Jans, Thomas"],["dc.contributor.author","Jendreizik, Lea"],["dc.contributor.author","Ketter, Johanna"],["dc.contributor.author","Legenbauer, Tanja"],["dc.contributor.author","Philipsen, Alexandra"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Renner, Tobias"],["dc.contributor.author","Retz, Wolfgang"],["dc.contributor.author","Rösler, Michael"],["dc.contributor.author","Thome, Johannes"],["dc.contributor.author","Uebel-von Sandersleben, Henrik"],["dc.contributor.author","von Wirth, Elena"],["dc.contributor.author","Zinnow, Toivo"],["dc.contributor.author","Hohmann, Sarah"],["dc.contributor.author","Millenet, Sabina"],["dc.contributor.author","Holz, Nathalie"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Brandeis, Daniel"],["dc.contributor.editorcorporation","ESCAlife-Consortium"],["dc.date.accessioned","2021-04-14T08:29:47Z"],["dc.date.available","2021-04-14T08:29:47Z"],["dc.date.issued","2021"],["dc.date.updated","2022-02-09T13:21:21Z"],["dc.description.sponsorship","German Federal Ministry of Education and Research"],["dc.identifier.doi","10.3390/brainsci11020214"],["dc.identifier.eissn","2076-3425"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82987"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.publisher","MDPI"],["dc.relation.eissn","2076-3425"],["dc.rights","https://creativecommons.org/licenses/by/4.0/"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","EEG Data Quality: Determinants and Impact in a Multicenter Study of Children, Adolescents, and Adults with Attention-Deficit/Hyperactivity Disorder (ADHD)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2017Journal Article Research Paper [["dc.bibliographiccitation.firstpage","660"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Biological psychiatry"],["dc.bibliographiccitation.lastpage","668"],["dc.bibliographiccitation.volume","82"],["dc.contributor.author","Albaugh, Matthew D."],["dc.contributor.author","Orr, Catherine"],["dc.contributor.author","Chaarani, Bader"],["dc.contributor.author","Althoff, Robert R."],["dc.contributor.author","Allgaier, Nicholas"],["dc.contributor.author","D'Alberto, N."],["dc.contributor.author","Hudson, Kelsey E."],["dc.contributor.author","Mackey, Scott"],["dc.contributor.author","Spechler, Philip A."],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Brühl, Rüdiger"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Buchel, Christian"],["dc.contributor.author","Cattrell, Anna"],["dc.contributor.author","Conrod, Patricia J."],["dc.contributor.author","Desrivieres, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Gallinat, Jürgen"],["dc.contributor.author","Goodman, Robert"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Grimmer, Yvonne"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Kappel, Viola"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Paillere Martinot, Marie-Laure"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Penttila, Jani"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Paus, Tomas"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Struve, Maren"],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Potter, Alexandra S."],["dc.date.accessioned","2017-09-07T11:52:08Z"],["dc.date.available","2017-09-07T11:52:08Z"],["dc.date.issued","2017"],["dc.description.abstract","BACKGROUND: Neuroimaging studies of attention-deficit/hyperactivity disorder (ADHD) have most commonly reported volumetric abnormalities in the basal ganglia, cerebellum, and prefrontal cortices. Few studies have examined the relationship between ADHD symptomatology and brain structure in population-based samples. We investigated the relationship between dimensional measures of ADHD symptomatology, brain structure, and reaction time variability-an index of lapses in attention. We also tested for associations between brain structural correlates of ADHD symptomatology and maps of dopaminergic gene expression.; METHODS: Psychopathology and imaging data were available for 1538 youths. Parent ratings of ADHD symptoms were obtained using the Development and Well-Being Assessment and the Strengths and Difficulties Questionnaire (SDQ). Self-reports of ADHD symptoms were assessed using the youth version of the SDQ. Reaction time variability was available in a subset of participants. For each measure, whole-brain voxelwise regressions with gray matter volume were calculated.; RESULTS: Parent ratings of ADHD symptoms (Development and Well-Being Assessment and SDQ), adolescent self-reports of ADHD symptoms on the SDQ, and reaction time variability were each negatively associated with gray matter volume in an overlapping region of the ventromedial prefrontal cortex. Maps of DRD1 and DRD2 gene expression were associated with brain structural correlates of ADHD symptomatology.; CONCLUSIONS: This is the first study to reveal relationships between ventromedial prefrontal cortex structure and multi-informant measures of ADHD symptoms in a large population-based sample of adolescents. Our results indicate that ventromedial prefrontal cortex structure is a biomarker for ADHD symptomatology. These findings extend previous research implicating the default mode network and dopaminergic dysfunction in ADHD. Copyright 2017 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.biopsych.2017.01.003"],["dc.identifier.gro","3151189"],["dc.identifier.pmid","28237458"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7966"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1873-2402"],["dc.subject","Attention-deficit/hyperactivity disorder; Inattention; Multi-informant; Neuroimaging; Reaction time variability; Ventromedial prefrontal cortex"],["dc.title","Inattention and Reaction Time Variability Are Linked to Ventromedial Prefrontal Volume in Adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]Details DOI PMID PMC2011Journal Article Research Paper [["dc.bibliographiccitation.firstpage","133"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie"],["dc.bibliographiccitation.lastpage","141"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Bender, Frauke"],["dc.contributor.author","Bock, Marita"],["dc.contributor.author","Bolte, Sven"],["dc.contributor.author","Möhler, Eva"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Goth, Kirstin"],["dc.date.accessioned","2017-09-07T11:52:46Z"],["dc.date.available","2017-09-07T11:52:46Z"],["dc.date.issued","2011"],["dc.description.abstract","OBJECTIVES: This study addresses the question whether personality dimensions differ between children with autism spectrum disorders (ASD) and attention deficit/hyperactivity disorder (ADHD), and whether these personality characteristics influence social problems in these groups of children.; METHODS: 68 children with ADHD (n = 32) and ASD (n = 36) were assessed with the Junior Temperament and Character Inventory (JTCI 7-11 R) and the Social Responsiveness Scale (SRS), as rated by the parents. Diagnosis of ASD was confirmed with standardized diagnostic instruments (ADOS und ADI-R).; RESULTS: Both children with ASD and ADHD displayed significantly decreased scores in persistence, self-directedness and cooperativeness compared to normative values. Additionally, children with ASD showed extremely low reward dependence and differed significantly from children with ADHD in the temperament dimensions harm avoidance and reward dependence as well as in the character dimensions self-directedness and cooperativeness. In both groups, personality dimensions, especially reward dependence, were predictive of social responsiveness, as assessed by the SRS.; CONCLUSION: The results suggest that specific personality characteristics are present already in young children with ASD and ADHD and may have an impact on their social competence."],["dc.identifier.doi","10.1024/1422-4917/a000099"],["dc.identifier.gro","3151262"],["dc.identifier.pmid","21442601"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8047"],["dc.language.iso","de"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1422-4917"],["dc.title","Temperament und soziale Reaktivität bei Autismus-Spektrum-Störungen und ADHS"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]Details DOI PMID PMC2009Journal Article [["dc.bibliographiccitation.firstpage","541"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie"],["dc.bibliographiccitation.lastpage","550"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Ristow, Gerhard"],["dc.contributor.author","Hermens, Angela"],["dc.contributor.author","Schmidt, Martin H."],["dc.contributor.author","Holtmann, Martin"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Poustka, Luise"],["dc.date.accessioned","2017-09-07T11:52:47Z"],["dc.date.available","2017-09-07T11:52:47Z"],["dc.date.issued","2009"],["dc.description.abstract","Fragestellung: Vorliegende Pilotstudie untersucht in Kooperation mit der Mannheimer Polizei die Wirksamkeit eines Präventionsprogramms für erstmalig delinquent gewordene Kinder mit dissozial- aggressivem und hyperkinetischem Problemverhalten. Methodik: In einer offenen Inanspruchnahme Studie wurden Kinder im Alter von 8–13 Jahren, die einmalig der Polizei durch delinquente Handlungen auffällig geworden waren; eingeschlossen. In einer ca. 4-monatigen Hometreatmentphase wurden insgesamt 24 Familien pädagogische und verhaltenstherapeutische Strategien vermittelt. Mittels DISYPS-KJ wurden vor und nach dem Training die hyperkinetisch Kernsymptomatik sowie oppositionell- aggressives und dissozial-aggressives Verhalten erfasst. Ergebnisse: Am Ende des Programms zeigte sich eine signifikante Symptomreduktion in den hyperkinetischen Subskalen sowie bei dissozial-aggressivem Verhalten. 88 % der Eltern schilderten eine deutliche Verbesserung beim Hauptproblem der Kinder. Schlussfolgerung: Vorliegendes Präventionsprogramm als indizierte Präventionsmaßnahme bei delinquenten Kindern zeigte sich nach einer ersten Beurteilung als effektiv in der Behandlung dissozial- aggressiver Auffälligkeiten."],["dc.identifier.doi","10.1024/1422-4917.37.6.541"],["dc.identifier.gro","3151270"],["dc.identifier.pmid","19890817"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8056"],["dc.language.iso","de"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1422-4917"],["dc.subject","Störung des Sozialverhalten; ADHS; Hometreatment; Behandlung im häuslichen Rahmen; Prävention"],["dc.title","Programm Zappelphilipp - Frühintervention bei delinquenten Kindern"],["dc.title.subtitle","Hometreatment als alternativer Behandlungsansatz bei polizeilich auffällig gewordenen Kindern"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]Details DOI PMID PMC2018Journal Article [["dc.bibliographiccitation.journal","Frontiers in Genetics"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Millenet, Sabina K."],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Heintz, Stefan"],["dc.contributor.author","Bach, Christiane"],["dc.contributor.author","Frank, Josef"],["dc.contributor.author","Vollstädt-Klein, Sabine"],["dc.contributor.author","Bokde, Arun"],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Quinlan, Erin B."],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Fröhner, Juliane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Lemaire, Herve"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure P."],["dc.contributor.author","Papadoulos, Dimitri O."],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Rietschel, Marcella"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Rob"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Hohmann, Sarah"],["dc.date.accessioned","2020-12-10T18:44:23Z"],["dc.date.available","2020-12-10T18:44:23Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3389/fgene.2018.00284"],["dc.identifier.eissn","1664-8021"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15711"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78431"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","COMT Val158Met Polymorphism and Social Impairment Interactively Affect Attention-Deficit Hyperactivity Symptoms in Healthy Adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI