Poustka, Luise

[["dc.bibliographiccitation.firstpage","489"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Public Health"],["dc.bibliographiccitation.lastpage","495"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Parchetka, Caroline"],["dc.contributor.author","Strache, Nicole"],["dc.contributor.author","Raffaelli, Bianca"],["dc.contributor.author","Gemmeke, Isabel"],["dc.contributor.author","Weiß, Katharina"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Buechel, Christian"],["dc.contributor.author","Conrod, Patricia"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Lemaitre, Herve"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Mennigen, Eva"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Paillère Martinot, Marie-Laure"],["dc.contributor.author","Papadopoulos, Dimitri"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Jurk, Sarah"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Vetter, Nora C."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Gallinat, Juergen"],["dc.date.accessioned","2018-06-04T09:18:35Z"],["dc.date.available","2018-06-04T09:18:35Z"],["dc.date.issued","2016"],["dc.description.abstract","Purpose The onset of substance use mostly occurs during adolescence. The aim of the present study is to investigate the relevance of personality on the basis of the NEO-Five-Factor Inventory (NEO-FFI) to future experiences with tobacco, alcohol and cannabis. Methods The test data were derived from the baseline assessment and first follow-up of the IMAGEN study, a European multicenter and multidisciplinary research project on adolescent mental health. In the present study 1004 participants were tested. The characterization of personality was conducted with the NEO-FFI at the age of 14 (T1). The data on substance use were collected with the European School Survey Project on Alcohol and Other Drugs (ESPAD) questionnaire at the age of 16 (T2). For the statistical analysis, t-tests and univariate analyses of variance were performed. Results The scores of Conscientiousness at T1 were significantly lower for adolescents with tobacco, alcohol and cannabis experiences at T2. We found lower scores of Agreeableness at T1 in participants with tobacco and cannabis use at T2. Extraversion at T1 was significantly higher for adolescents with smoking experiences at T2. No significant associations between Neuroticism or Openness and future substance use were observed. Conclusion Low scores of Conscientiousness and Agreeableness seem to have the greatest value for a prediction of later experiences with substance use. As the present study is the first one to examine the predictive value of the NEO-FFI for future substance use in an adolescent sample, further studies are necessary to enable a better applicability in a clinical context."],["dc.identifier.doi","10.1007/s10389-016-0747-2"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/14854"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.title","Predictive utility of the NEO-FFI for later substance experiences among 16-year-old adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","435"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","JAMA Psychiatry"],["dc.bibliographiccitation.volume","76"],["dc.contributor.author","Luo, Qiang"],["dc.contributor.author","Chen, Qiang"],["dc.contributor.author","Wang, Wenjia"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Macare, Christine"],["dc.contributor.author","Robert, Gabriel H."],["dc.contributor.author","Cui, Jing"],["dc.contributor.author","Guedj, Mickaël"],["dc.contributor.author","Palaniyappan, Lena"],["dc.contributor.author","Kherif, Ferath"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Paillère-Martinot, Marie-Laure"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Callicott, Joseph H."],["dc.contributor.author","Mattay, Venkata S."],["dc.contributor.author","Pausova, Zdenka"],["dc.contributor.author","Dartigues, Jean-François"],["dc.contributor.author","Tzourio, Christophe"],["dc.contributor.author","Crivello, Fabrice"],["dc.contributor.author","Berman, Karen F."],["dc.contributor.author","Li, Fei"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Weinberger, Daniel R."],["dc.contributor.author","Murray, Robin M."],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Feng, Jianfeng"],["dc.date.accessioned","2019-07-09T11:51:24Z"],["dc.date.available","2019-07-09T11:51:24Z"],["dc.date.issued","2019"],["dc.description.abstract","Importance: Deviation from normal adolescent brain development precedes manifestations of many major psychiatric symptoms. Such altered developmental trajectories in adolescents may be linked to genetic risk for psychopathology. Objective: To identify genetic variants associated with adolescent brain structure and explore psychopathologic relevance of such associations. Design, Setting, and Participants: Voxelwise genome-wide association study in a cohort of healthy adolescents aged 14 years and validation of the findings using 4 independent samples across the life span with allele-specific expression analysis of top hits. Group comparison of the identified gene-brain association among patients with schizophrenia, unaffected siblings, and healthy control individuals. This was a population-based, multicenter study combined with a clinical sample that included participants from the IMAGEN cohort, Saguenay Youth Study, Three-City Study, and Lieber Institute for Brain Development sample cohorts and UK biobank who were assessed for both brain imaging and genetic sequencing. Clinical samples included patients with schizophrenia and unaffected siblings of patients from the Lieber Institute for Brain Development study. Data were analyzed between October 2015 and April 2018. Main Outcomes and Measures: Gray matter volume was assessed by neuroimaging and genetic variants were genotyped by Illumina BeadChip. Results: The discovery sample included 1721 adolescents (873 girls [50.7%]), with a mean (SD) age of 14.44 (0.41) years. The replication samples consisted of 8690 healthy adults (4497 women [51.8%]) from 4 independent studies across the life span. A nonsynonymous genetic variant (minor T allele of rs13107325 in SLC39A8, a gene implicated in schizophrenia) was associated with greater gray matter volume of the putamen (variance explained of 4.21% in the left hemisphere; 8.66; 95% CI, 6.59-10.81; P = 5.35 × 10-18; and 4.44% in the right hemisphere; t = 8.90; 95% CI, 6.75-11.19; P = 6.80 × 10-19) and also with a lower gene expression of SLC39A8 specifically in the putamen (t127 = -3.87; P = 1.70 × 10-4). The identified association was validated in samples across the life span but was significantly weakened in both patients with schizophrenia (z = -3.05; P = .002; n = 157) and unaffected siblings (z = -2.08; P = .04; n = 149). Conclusions and Relevance: Our results show that a missense mutation in gene SLC39A8 is associated with larger gray matter volume in the putamen and that this association is significantly weakened in schizophrenia. These results may suggest a role for aberrant ion transport in the etiology of psychosis and provide a target for preemptive developmental interventions aimed at restoring the functional effect of this mutation."],["dc.identifier.doi","10.1001/jamapsychiatry.2018.4126"],["dc.identifier.pmid","30649180"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16122"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59943"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation","info:eu-repo/grantAgreement/EC/H2020/720270/EU//HBP SGA1"],["dc.relation","info:eu-repo/grantAgreement/EC/H2020/695313/EU//STRATIFY"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/602450/EU//IMAGEMEND"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/603016/EU//MATRICS"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Genetics"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Millenet, Sabina K."],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Heintz, Stefan"],["dc.contributor.author","Bach, Christiane"],["dc.contributor.author","Frank, Josef"],["dc.contributor.author","Vollstädt-Klein, Sabine"],["dc.contributor.author","Bokde, Arun"],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Quinlan, Erin B."],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Fröhner, Juliane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Lemaire, Herve"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure P."],["dc.contributor.author","Papadoulos, Dimitri O."],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Rietschel, Marcella"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Rob"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Hohmann, Sarah"],["dc.date.accessioned","2020-12-10T18:44:23Z"],["dc.date.available","2020-12-10T18:44:23Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3389/fgene.2018.00284"],["dc.identifier.eissn","1664-8021"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15711"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78431"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","COMT Val158Met Polymorphism and Social Impairment Interactively Affect Attention-Deficit Hyperactivity Symptoms in Healthy Adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.firstpage","1019"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Molecular Psychiatry"],["dc.bibliographiccitation.lastpage","1028"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Barker, Edward D"],["dc.contributor.author","Ing, Alex"],["dc.contributor.author","Biondo, Francesca"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Pingault, Jean-Baptiste"],["dc.contributor.author","Du Rietz, Ebba"],["dc.contributor.author","Zhang, Yuning"],["dc.contributor.author","Ruggeri, Barbara"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Hohmann, Sarah"],["dc.contributor.author","Bokde, Arun L. W"],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Sounga-Barke, Edmund"],["dc.contributor.author","Bowling, April B."],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Asherson, Philip"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure Paillère"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Papadopoulos-Orfanos, Dimitri"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Smolka, Michael N"],["dc.contributor.author","Vetter, Nora C."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.date.accessioned","2021-04-14T08:28:41Z"],["dc.date.available","2021-04-14T08:28:41Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1038/s41380-019-0444-y"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82679"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1476-5578"],["dc.relation.issn","1359-4184"],["dc.title","Do ADHD-impulsivity and BMI have shared polygenic and neural correlates?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","European child & adolescent psychiatry"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Bartholdy, Savani"],["dc.contributor.author","Allen, Karina"],["dc.contributor.author","Hodsoll, John"],["dc.contributor.author","O'Daly, O. G."],["dc.contributor.author","Campbell, Iain C."],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Conrod, Patricia J."],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Gallinat, Jürgen"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Mennigen, Eva"],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Schmidt, Ulrike"],["dc.date.accessioned","2017-09-07T11:52:08Z"],["dc.date.available","2017-09-07T11:52:08Z"],["dc.date.issued","2017"],["dc.description.abstract","This study investigated the prevalence of disordered eating cognitions and behaviours across mid-adolescence in a large European sample, and explored the extent to which prevalence ratings were affected by informant (parent/adolescent), or the sex or age of the adolescent. The Development and Well-Being Assessment was completed by parent-adolescent dyads at age 14 (n=2225) and again at age 16 (n=1607) to explore the prevalence of 7 eating disorder symptoms (binge eating, purging, fear of weight gain, distress over shape/weight, avoidance of fattening foods, food restriction, and exercise for weight loss). Informant agreement was assessed using kappa coefficients. Generalised estimating equations were performed to explore the impact of age, sex and informant on symptom prevalence. Slight to fair agreement was observed between parent and adolescent reports (kappa estimates between 0.045 and 0.318); however, this was largely driven by agreement on the absence of behaviours. Disordered eating behaviours were more consistently endorsed amongst girls compared to boys (odds ratios: 2.96-5.90) and by adolescents compared to their parents (odds ratios: 2.71-9.05). Our data are consistent with previous findings in epidemiological studies. The findings suggest that sex-related differences in the prevalence of disordered eating behaviour are established by mid-adolescence. The greater prevalence rates obtained from adolescent compared to parent reports may be due to the secretive nature of the behaviours and/or lack of awareness by parents. If adolescent reports are overlooked, the disordered behaviour may have a greater opportunity to become more entrenched."],["dc.identifier.doi","10.1007/s00787-016-0935-1"],["dc.identifier.gro","3151180"],["dc.identifier.pmid","28050706"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7956"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1435-165X"],["dc.subject","Parent; Adolescent; Epidemiology; Eating disorders"],["dc.title","Identifying disordered eating behaviours in adolescents: how do parent and adolescent reports differ by sex and age?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2648"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Molecular Psychiatry"],["dc.bibliographiccitation.lastpage","2671"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Mascarell Maričić, Lea"],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Rosenthal, Annika"],["dc.contributor.author","Ripke, Stephan"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Barker, Gareth J."],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Itterman, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure Paillère"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Hohmann, Sarah"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Kaminski, Jakob"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Heinz, Andreas"],["dc.date.accessioned","2021-04-14T08:25:50Z"],["dc.date.available","2021-04-14T08:25:50Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1038/s41380-020-0822-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81743"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1476-5578"],["dc.relation.issn","1359-4184"],["dc.title","The IMAGEN study: a decade of imaging genetics in adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","544"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Nature Human Behaviour"],["dc.bibliographiccitation.lastpage","558"],["dc.bibliographiccitation.volume","4"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Ing, Alex"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Tay, Nicole"],["dc.contributor.author","Luo, Qiang"],["dc.contributor.author","Francesca, Biondo"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Barker, Gareth J."],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Feng, Jianfeng"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Grigis, Antoine"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure Paillère"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.date.accessioned","2021-04-14T08:26:46Z"],["dc.date.available","2021-04-14T08:26:46Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1038/s41562-020-0846-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82071"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","2397-3374"],["dc.title","Neurobehavioural characterisation and stratification of reinforcement-related behaviour"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","844"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","American Journal of Psychiatry"],["dc.bibliographiccitation.lastpage","854"],["dc.bibliographiccitation.volume","177"],["dc.contributor.author","Shen, Chun"],["dc.contributor.author","Luo, Qiang"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Zhao, Qi"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Millenet, Sabina"],["dc.contributor.author","Bokde, Arun L.W."],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Paillère-Martinot, Marie-Laure"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Papadopoulos Orfanos, Dimitri"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Li, Fei"],["dc.contributor.author","Feng, Jianfeng"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Sahakian, Barbara J."],["dc.date.accessioned","2021-04-14T08:32:48Z"],["dc.date.available","2021-04-14T08:32:48Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1176/appi.ajp.2020.19020183"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/84024"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1535-7228"],["dc.relation.issn","0002-953X"],["dc.title","Neural Correlates of the Dual-Pathway Model for ADHD in Adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","436"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of the American Academy of Child and Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","444"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Xu, Bing"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Macare, Christine"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Cattrell, Anna"],["dc.contributor.author","Conrod, Patricia J."],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Gallinat, Jürgen"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure Paillère"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Desrivières, Sylvane"],["dc.date.accessioned","2017-09-07T11:52:07Z"],["dc.date.available","2017-09-07T11:52:07Z"],["dc.date.issued","2017"],["dc.description.abstract","Objective:In a recent genomewide association study of subcortical brain volumes, a common genetic variation at rs945270 was identified as having the strongest effect on putamen volume, a brain measurement linked to familial risk for attention-deficit/hyperactivity disorder (ADHD). To determine whether rs945270 might be a genetic determinant of ADHD, its effects on ADHD-related symptoms and neural mechanisms of ADHD, such as response inhibition and reward sensitivity, were explored.Method:A large population sample of 1,834 14-year-old adolescents was used to test the effects of rs945270 on ADHD symptoms assessed through the Strengths and Difficulties Questionnaire and region-of-interest analyses of putamen activation by functional magnetic resonance imaging using the stop signal and monetary incentive delay tasks, assessing response inhibition and reward sensitivity, respectively.Results:There was a significant link between rs945270 and ADHD symptom scores, with the C allele associated with lower symptom scores, most notably hyperactivity. In addition, there were sex-specific effects of this variant on the brain. In boys, the C allele was associated with lower putamen activity during successful response inhibition, a brain response that was not associated with ADHD symptoms. In girls, putamen activation during reward anticipation increased with the number of C alleles, most significantly in the right putamen. Remarkably, right putamen activation during reward anticipation tended to negatively correlate with ADHD symptoms.Conclusion:These results indicate that rs945270 might contribute to the genetic risk of ADHD partly through its effects on hyperactivity and reward processing in girls."],["dc.identifier.doi","10.1016/j.jaac.2017.02.009"],["dc.identifier.gro","3151184"],["dc.identifier.pmid","28433093"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7960"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1527-5418"],["dc.subject","rs945270; putamen; attention-deficit/hyperactivity disorder; reward anticipation; response control"],["dc.title","Impact of a Common Genetic Variation Associated With Putamen Volume on Neural Mechanisms of Attention-Deficit/Hyperactivity Disorder"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]