Konietschke, Frank

[["dc.bibliographiccitation.firstpage","490"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","The Breast Journal"],["dc.bibliographiccitation.lastpage","497"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Angic, Besim"],["dc.contributor.author","Sossalla, Samuel T."],["dc.contributor.author","Konietschke, Frank"],["dc.contributor.author","Obenauer, Silvia"],["dc.date.accessioned","2018-11-07T08:39:34Z"],["dc.date.available","2018-11-07T08:39:34Z"],["dc.date.issued","2010"],["dc.description.abstract","The object of this study was to assess the clinical usefulness of computer-assisted diagnosis (CAD) in the interpretation of early-research, benign and malignant mammograms in dependence on readers' experience with CAD. CAD was applied on digital mammograms of 303 patients who were divided into three groups: early-research (n = 103), benign (n = 102) and malignant group (n = 98). Mammograms were analyzed by three readers with different experience in evaluating mammograms (medical student, an assistant and an attending physician specifically trained in mammography). All images were presented accidentally with and without the influence of CAD and from different patient groups. The mammograms were classified according to BI-RADS classification. To evaluate readers' sensitivity and specificity with and without the application of the CAD system, ROC analysis and the corresponding area under the curve (AUC) were evaluated for each reader. Afterwards significant differences of the accuracy according to readers experience and according to the assistance of the CAD system were calculated. All readers have an account of accuracy by using CAD in both patient groups. The highest benefit has the student (10% increase of the AUC) followed by the resident (4%) and at least followed by the mammography fellow (3%). There are significant varieties of the accuracy in addiction to the readers' experience and to the examination method with and without CAD system. Patient group has not a significant influence to the elevation of accuracy by using the CAD. All three readers have nearly the same increase of AUC in the examinations of malignant and early-research group summarized and of the malignant group only. Finally, the increase of accuracy depends on the readers' experience. For all patient groups CAD-application causes a steeply increase of the ROC curve and consequently a gain of sensitivity."],["dc.identifier.doi","10.1111/j.1524-4741.2010.00963.x"],["dc.identifier.isi","000281667100006"],["dc.identifier.pmid","20642459"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19028"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1524-4741"],["dc.relation.issn","1075-122X"],["dc.title","Computer-assisted Diagnosis in Full-field Digital Mammography-Results in Dependence of Readers Experiences"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","92"],["dc.bibliographiccitation.journal","Clinical Imaging"],["dc.bibliographiccitation.lastpage","95"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Wienbeck, Susanne"],["dc.contributor.author","Bauer, Lukas"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Konietschke, Frank"],["dc.contributor.author","Derlin, Thorsten"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Sohns, Jan Martin"],["dc.date.accessioned","2020-12-10T14:23:07Z"],["dc.date.available","2020-12-10T14:23:07Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.clinimag.2017.06.005"],["dc.identifier.issn","0899-7071"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71842"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Prevalence and clinical significance of incidental extra-mammary findings in breast magnetic resonance imaging: A retrospective study of 1070 patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","418"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Clinical Imaging"],["dc.bibliographiccitation.lastpage","424"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Angic, Besim Cetin"],["dc.contributor.author","Sossalla, Samuel T."],["dc.contributor.author","Konietschke, Frank"],["dc.contributor.author","Obenauer, Silvia"],["dc.date.accessioned","2018-11-07T08:37:23Z"],["dc.date.available","2018-11-07T08:37:23Z"],["dc.date.issued","2010"],["dc.description.abstract","Aim To assess time expenditure using the influence of computer assisted detection (CAD) system in the interpretation of the dependence of early research and benign and malignant mammograms on readers experience Materials and Methods CAD (Image Checker V2 3 R2 Technology Los Altos CA USA) was prospectively applied on digital mammograms of 303 patients [early research (n=103) benign (n=102), and malignant group (n=98)] Mammograms were analyzed by three readers with varying experience in evaluating mammograms (medical student, resident and attending) according to the BI-RADS classification Time was stopped and recorded All images were presented randomly with and without the influence of CAD and from the different patient groups To evaluate the statistical significance, the corresponding P value for time to read the mammograms in addition to different patient groups, application of CAD, readers experience and interaction of reader was calculated Results The attending needs, independent of CAD application, the least time, followed by the medical assistant and the student In all three patient groups, CAD adoption elongates reading time of the student and the resident The medical specialist needs with and without CAD median the same time In the early research group, no significant differences were registered (P= 1343) Concerning readers experience, there is an explicit significant difference (P< 0001) The application of CAD correlates with the corresponding readers experience and also provides a not significant result In comparison, the P value for the malignant and benign groups shows significant interactions between the readers experiences as well as CAD application Conclusion The future role of CAD application depends on whether sensitivity can be increased and time expenditure caused by false-positive marks can be decreased In the future, second reading could be substituted by a CAD system if the reader has a wide professional experience (C) 2010 Elsevier Inc All rights reserved"],["dc.identifier.doi","10.1016/j.clinimag.2009.10.039"],["dc.identifier.isi","000285034600004"],["dc.identifier.pmid","21092870"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18517"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1873-4499"],["dc.relation.issn","0899-7071"],["dc.title","CAD in full-field digital mammography-influence of reader experience and application of CAD on interpretation of time"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","512"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Acta Radiologica"],["dc.bibliographiccitation.lastpage","521"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Mangelsdorf, Johanna"],["dc.contributor.author","Sossalla, Samuel T."],["dc.contributor.author","Konietschke, Frank"],["dc.contributor.author","Obenauer, Silvia"],["dc.date.accessioned","2018-11-07T08:42:21Z"],["dc.date.available","2018-11-07T08:42:21Z"],["dc.date.issued","2010"],["dc.description.abstract","Background: Advances in CT technology from single to multi-detector row CT (MDCT) permit a high resolution and volumetric presentation of pulmonary lesions. This implicates emerging measurement techniques that need to be contrasted with established methods. Purpose: To compare bidimensional, unidimensional, and volumetric methods for evaluation of treatment response in patients with lung lesions. Material and Methods: This study comprised 68 patients with pulmonary lesions who underwent a total of 276 64-MDCTs of chest at baseline and follow-up. RECIST and WHO criteria were used for unidimensional and bidimensional methods and region growing (RG) for volumetry. Patients were classified into four response categories. Respectively, two measurement techniques were contrasted and the. index was calculated. For intra-observer reproducibility the relative measurement error (RME) and. index with regard to agreement of response categories were evaluated. Results: Comparison of WHO und RECIST criteria achieves high correlation with. indices of 0.76 and 0.82. In particular, lesions with moderate increase of size in the range of 25-44% for bidimensional and 12-29% for unidimensional measurement result in different response categories when applying WHO and RECIST criteria. WHO criteria delivered PD more often than RECIST. kappa indices of 0.79 and 0.87 were attained in comparison of RECIST and RG, and 0.83 and 0.84 for WHO and RG. RME was 2.82% for RECIST, 7.53% for WHO, and 8.97% for RG. Intra-observer reproducibility was 95% for RECIST, 95% for WHO, and 96% for RG. Conclusion: The comparison of all methods resulted in no statistically significant differences. WHO criteria seemed to diverge the most, they declared several lesions prematurely as progression, and showed no benefit in comparison to RECIST. RG showed the best reproducibility, considered irregular lesions, was slightly superior to RECIST, and could be applied uniformly. Unidimensional measurement represents an adequate alternative with the advantage of better clinical work flow."],["dc.identifier.doi","10.3109/02841851003674520"],["dc.identifier.isi","000278808900006"],["dc.identifier.pmid","20540683"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19677"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Taylor & Francis Ltd"],["dc.relation.issn","0284-1851"],["dc.title","Measurement of response of pulmonal tumors in 64-slice MDCT"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]