Gevensleben, Holger

[["dc.bibliographiccitation.firstpage","149"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","International Journal of Psychophysiology"],["dc.bibliographiccitation.lastpage","157"],["dc.bibliographiccitation.volume","74"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Holl, Birgit"],["dc.contributor.author","Albrecht, Bjoern"],["dc.contributor.author","Schlamp, Dieter"],["dc.contributor.author","Kratz, Oliver"],["dc.contributor.author","Studer, Petra"],["dc.contributor.author","Wangler, Susanne"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Heinrich, Hartmut"],["dc.date.accessioned","2018-11-07T11:22:46Z"],["dc.date.available","2018-11-07T11:22:46Z"],["dc.date.issued","2009"],["dc.description.abstract","In a randomized controlled trial, neurofeedback (NF) training was found to be superior to a computerised attention skills training concerning the reduction of ADHD symptomatology (Gevensleben et al., 2009). The aims of this investigation were to assess the impact of different NF protocols (theta/beta training and training of slow cortical potentials, SCPs) on the resting EEG and the association between distinct EEG measures and behavioral improvements. In 72 (of initially 102) children with ADHD, aged 8-12, EEG changes after either a NF training (n = 46) or the control training (n = 26) could be studied. The combined NF training consisted of one block of theta/beta training and one block of SCP training, each block comprising 18 units of 50 minutes (balanced order). Spontaneous EEG was recorded in a two-minute resting condition before the start of the training, between the two training blocks and after the end of the training. Activity in the different EEG frequency bands was analyzed. In contrast to the control condition, the combined NF training was accompanied by a reduction of theta activity. Protocol-specific EEG changes (theta/beta training: decrease of posterior-midline theta activity; SCP training: increase of central-midline alpha activity) were associated with improvements in the German ADHD rating scale. Related EEG-based predictors were obtained. Thus, differential EEG patterns for theta/beta and SCP training provide further evidence that distinct neuronal mechanisms may contribute to similar behavioral improvements in children with ADHD. (C) 2009 Elsevier B.V. All rights reserved."],["dc.description.sponsorship","German Research Foundation [HE 4536/2, MO 726/2, RO 698/4]"],["dc.identifier.doi","10.1016/j.ijpsycho.2009.08.005"],["dc.identifier.isi","000271783100010"],["dc.identifier.pmid","19712709"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56049"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0167-8760"],["dc.title","Distinct EEG effects related to neurofeedback training in children with ADHD: A randomized controlled trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","447"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Expert Review of Neurotherapeutics"],["dc.bibliographiccitation.lastpage","460"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Heinrich, Hartmut"],["dc.date.accessioned","2018-11-07T09:11:34Z"],["dc.date.available","2018-11-07T09:11:34Z"],["dc.date.issued","2012"],["dc.description.abstract","Neurofeedback (NF), a type of neurobehavioral training, has gained increasing attention in recent years, especially concerning the treatment of children with ADHD. Promising results have emerged from recent randomized controlled studies, and thus, NF is on its way to becoming a valuable addition to the multimodal treatment of ADHD. In this review, we summarize the randomized controlled trials in children with ADHD that have been published within the last 5 years and discuss issues such as the efficacy and specificity of effects, treatment fidelity and problems inherent in placebo-controlled trials of NF. Directions for future NF research are outlined, which should further address specificity and help to determine moderators and mediators to optimize and individualize NF training. Furthermore, we describe methodological (tomographic NF) and technical ('tele-NF') developments that may also contribute to further improvements in treatment outcome."],["dc.description.sponsorship","German Research Foundation [HE 4536/2, MO 726/2, RO 698/4]"],["dc.identifier.doi","10.1586/ERN.12.22"],["dc.identifier.isi","000302982600013"],["dc.identifier.pmid","22449216"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26752"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Expert Reviews"],["dc.relation.issn","1473-7175"],["dc.title","Neurofeedback in children with ADHD: validation and challenges"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","20"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Brain Topography"],["dc.bibliographiccitation.lastpage","32"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Kleemeyer, Maike"],["dc.contributor.author","Rothenberger, Lillian Geza"],["dc.contributor.author","Studer, Petra"],["dc.contributor.author","Flaig-Roehr, Andrea"],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Heinrich, Hartmut"],["dc.date.accessioned","2018-11-07T09:47:03Z"],["dc.date.available","2018-11-07T09:47:03Z"],["dc.date.issued","2014"],["dc.description.abstract","Among the different neuromodulation techniques, neurofeedback (NF) is gaining increasing interest in the treatment of children with attention-deficit/hyperactivity disorder (ADHD). In this article, a methodological framework is summarised considering the training as a neuro-behavioural treatment. Randomised controlled trials are selectively reviewed. Results from two smaller-scale studies are presented with the first study comprising a tomographic analysis over the course of a slow cortical potential (SCP) training and a correlational analysis of regulation skills and clinical outcome in children with ADHD. In the second study, ADHD-related behaviour was studied in children with tic disorder who either conducted a SCP training or a theta/low-beta (12-15 Hz) training (single-blind, randomised design). Both studies provide further evidence for the specificity of NF effects in ADHD. Based on these findings, a refined model of the mechanisms contributing to the efficacy of SCP training is developed. Despite a number of open questions concerning core mechanisms, moderators and mediators, NF (theta/beta and SCP) training seems to be on its way to become a valuable and ethically acceptable module in the treatment of children with ADHD."],["dc.identifier.doi","10.1007/s10548-013-0285-y"],["dc.identifier.isi","000329226500004"],["dc.identifier.pmid","23563906"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35021"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1573-6792"],["dc.relation.issn","0896-0267"],["dc.title","Neurofeedback in ADHD: Further Pieces of the Puzzle"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","666"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PRAXIS DER KINDERPSYCHOLOGIE UND KINDERPSYCHIATRIE"],["dc.bibliographiccitation.lastpage","676"],["dc.bibliographiccitation.volume","60"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Heinrich, Hartmut"],["dc.date.accessioned","2018-11-07T09:01:58Z"],["dc.date.available","2018-11-07T09:01:58Z"],["dc.date.issued","2011"],["dc.description.abstract","The Usage of Neurofeedback in Children with ADHD: The Method and its Evaluation Neurofeedback is a computer-based behavior training, which is gaining increasing interest in the treatment of children with attention-deficit/hyperactivity disorder (ADHD). This article gives an introduction to neurofeedback and summarizes the state of research, discussing inter alia methodical aspects (e. g., requirements to a control training). Evaluation studies conducted so far indicate clinical efficacy. For example, neurofeedback training was superior to a computerized attention training in a randomized controlled trial (medium effect size). Follow-up investigations suggest that treatment effects remain stable (at least six months). At the clinical level, comparable improvements could be obtained for the neurofeedback protocols theta/beta training and training of slow cortical potentials. Neurophysiological findings document different mechanisms of theta/beta training and slow cortical potential training. Future studies should further elucidate the specificity of training effects related to the kind of training and certain disorders and address how to optimize and individualize neurofeedback training."],["dc.identifier.isi","000297770700006"],["dc.identifier.pmid","22145423"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24564"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Vandenhoeck & Ruprecht"],["dc.relation.issn","0032-7034"],["dc.title","The Usage of Neurofeedback in Children with ADHD: The Method and its Evaluation"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","942"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Clinical Neurophysiology"],["dc.bibliographiccitation.lastpage","950"],["dc.bibliographiccitation.volume","122"],["dc.contributor.author","Wangler, Susanne"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Albrecht, Bjoern"],["dc.contributor.author","Studer, Petra"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Heinrich, Hartmut"],["dc.date.accessioned","2018-11-07T08:56:36Z"],["dc.date.available","2018-11-07T08:56:36Z"],["dc.date.issued","2011"],["dc.description.abstract","Objective: In a randomized controlled trial, we could demonstrate clinical efficacy of neurofeedback (NF) training for children with ADHD (Gevensleben et al., 2009a). The present investigation aimed at learning more about the neuronal mechanisms of NF training. Methods: Children with ADHD either completed a NF training or a computerized attention skills training (ratio 3: 2). NF training consisted of one block of theta/beta training and one block of slow cortical potential (SCP) training, each comprising 18 training units. At three times (pre-training, between the two training blocks and at post-training), event-related potentials (ERP) were recorded during the Attention Network Test. ERP analysis focused on the P3, reflecting inter alia attentional resources for stimulus evaluation, and the contingent negative variation (CNV), primarily related to cognitive preparation. Results: After NF training, an increase of the CNV in cue trials could be observed, which was specific for the SCP training. A larger pre-training CNV was associated with a larger reduction of ADHD symptomatology for SCP training. Conclusions: CNV effects reflect neuronal circuits underlying resource allocation during cognitive preparation. These distinct ERP effects are closely related to a successful NF training in children with ADHD. In future studies, neurophysiological recordings could help to optimize and individualize NF training. Significance: The findings contribute to a better understanding of the mechanisms underlying NF training in children with ADHD. (C) 2010 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.clinph.2010.06.036"],["dc.identifier.isi","000290098700014"],["dc.identifier.pmid","20843737"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23188"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","1388-2457"],["dc.title","Neurofeedback in children with ADHD: Specific event-related potential findings of a randomized controlled trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","409"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie"],["dc.bibliographiccitation.lastpage","420"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Heinrich, Hartmut"],["dc.date.accessioned","2018-11-07T08:37:52Z"],["dc.date.available","2018-11-07T08:37:52Z"],["dc.date.issued","2010"],["dc.description.abstract","Neurofeedback training in children with ADHD: behavioral and neurophysiological effects In a multicentre randomised controlled trial, we evaluated the clinical efficacy of neurofeedback (NF) training in children with ADHD and investigated the mechanism underlying a successful training. We used an attention skills training, coupled with the training setting and demands made upon participants, as the control condition. At the behavioural level. NF was superior to the control group concerning core ADHD symptomatology as well as associated domains. For the primary outcome measure (improvement in the FBB-HKS total score), the effect size was .60. The same pattern of results was obtained at the 6-month follow-up. Thus. NE may be seen as a clinically effective module in the treatment of children with ADHD. At the neurophysiological level (EEG, ERPs), specific effects for the two NF protocols, theta/beta training; and training of slow cortical potentials were demonstrated. For example, for theta/beta training, a decrease of theta activity in the EEG was associated with a reduction of ADHD symptomatology. SCP training was accompanied inter cilia by an increase in the contingent negative variation in the attention network test; thus, children were able to allocate more resources for preparation. EEG- and ERP-based predictors were also found. The present article reviewed the findings of the original papers related to the trial and outlines future research topics."],["dc.identifier.doi","10.1024/1422-4917/a000070"],["dc.identifier.isi","000284856100004"],["dc.identifier.pmid","21128217"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18644"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Verlag Hans Huber"],["dc.relation.issn","1664-2880"],["dc.relation.issn","1422-4917"],["dc.title","Neurofeedback training in children with ADHD: behavioral and neurophysiological effects"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","96"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Neuroscience Letters"],["dc.bibliographiccitation.lastpage","99"],["dc.bibliographiccitation.volume","403"],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Heinrich, Hartmut"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2018-11-07T09:31:34Z"],["dc.date.available","2018-11-07T09:31:34Z"],["dc.date.issued","2006"],["dc.description.abstract","Deficient inhibitory processes within the sensorimotor circuit, reflected by a shortened cortical silent period (CSP), have previously been described in both children and adults with tic disorders (TD) using transcranial magnetic stimulation (TMS). In contrast to adults, tic distribution (presence or absence of distal tics) did not affect CSP duration in children. The aim of this developmental TMS study was to clarify this striking difference. 127 children with TD were stratified into three age-groups (8-11.5, 11.5-15, 15-19 years) with and without distal tics. CSP was recorded from the abductor digiti minimi. Statistics revealed a significant tic distribution x age interaction effect. Only in the 15-19 years subgroup, CSP was shorter in patients with distal tics in comparison to patients without distal tics (94.1 +/- 54.1 ms versus 135.2 +/- 36.8 ms at a stimulus intensity of active motor threshold plus 30%). Inhibitory processes in the sensorimotor circuit could reflect developmental aspects of tic phenomenology, particularly tic distribution during adolescence. (c) 2006 Elsevier Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.neulet.2006.04.021"],["dc.identifier.isi","000239611500019"],["dc.identifier.pmid","16690208"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31557"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","0304-3940"],["dc.title","Distribution and inhibitory processes in the sensorimotor circuit during adolescence: A cross-sectional TMS study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","772"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Biological Psychiatry"],["dc.bibliographiccitation.lastpage","775"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Heinrich, Hartmut"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Freisleder, Franz Joseph"],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2018-11-07T10:49:46Z"],["dc.date.available","2018-11-07T10:49:46Z"],["dc.date.issued","2004"],["dc.description.abstract","Background: Learned self-control of slow cortical potentials (SCPs) may lead to behavioral improvement in attention-deficit/hyperactivity disorder (ADHD). Hence, training effects should also be reflected at the neurophysiological level. Methods. Thirteen children with ADHD, aged 7-13 years, performed 25 SCP training sessions within 3 weeks. Before and after training, the German ADHD rating scale was completed by parents, and event-related potentials were recorded in a cued continuous performance test (CPT). For a waiting-list group of nine children with ADHD, the same testing was applied. Results: ADHD symptomatology was reduced by approximately 25% after SCP training. Moreover, a decrease of impulsivity errors and an increase of the contingent negative variation were observed in the CPT task. Conclusions. This study provides first evidence for both positive behavioral and specific neurophysiological effects of SCP training in children with ADHD."],["dc.identifier.doi","10.1016/j.biopsych.2003.11.013"],["dc.identifier.isi","000220443300016"],["dc.identifier.pmid","15039008"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/48506"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.notes.submitter","Najko"],["dc.relation.issn","0006-3223"],["dc.title","Training of slow cortical potentials in attention-deficit/hyperactivity disorder: Evidence for positive behavioral and neurophysiological effects"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","80"],["dc.bibliographiccitation.journal","International Journal of Psychophysiology"],["dc.bibliographiccitation.lastpage","88"],["dc.bibliographiccitation.volume","112"],["dc.contributor.author","van Doren, Jessica"],["dc.contributor.author","Heinrich, Hartmut"],["dc.contributor.author","Bezold, Mareile"],["dc.contributor.author","Reuter, Nina"],["dc.contributor.author","Kratz, Oliver"],["dc.contributor.author","Horndasch, Stefanie"],["dc.contributor.author","Berking, Matthias"],["dc.contributor.author","Ros, Tomas"],["dc.contributor.author","Gevensleben, Holger"],["dc.contributor.author","Moll, Gunther H."],["dc.contributor.author","Studer, Petra"],["dc.date.accessioned","2018-11-07T10:28:08Z"],["dc.date.available","2018-11-07T10:28:08Z"],["dc.date.issued","2017"],["dc.description.abstract","Neurofeedback (NF) is increasingly used as a therapy for attention-deficit/hyperactivity disorder (ADHD), however behavioral improvements require 20 plus training sessions. More economic evaluation strategies are needed to test methodological optimizations and mechanisms of action. In healthy adults, neuroplastic effects have been demonstrated directly after a single session of NF training. The aim of our study was to test the feasibility of short-term theta/beta NF in children with ADHD and to learn more about the mechanisms underlying this protocol. Children with ADHD conducted two theta/beta NF sessions. In the first half of the sessions, three NF trials (puzzles as feedback animations) were run with pre- and post-reading and picture search tasks. A significant decrease of the theta/beta ratio (TBR), driven by a decrease of theta activity, was found in the NF trials of the second session demonstrating rapid and successful neuroregulation by children with ADHD. For pre-post comparisons, children were split into good vs. poor regulator groups based on the slope of their TBR over the NF trials. For the reading task, significant EEG changes were seen for the theta band from pre- to post-NF depending on individual neuroregulation ability. This neuroplastic effect was not restricted to the feedback electrode Cz, but appeared as a generalized pattern, maximal over midline and right-hemisphere electrodes. Our findings indicate that short-term NF may be a valuable and economical tool to study the neuroplastic mechanisms of targeted NF protocols in clinical disorders, such as theta/beta training in children with ADHD. (C) 2016 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.ijpsycho.2016.11.004"],["dc.identifier.isi","000393245600010"],["dc.identifier.pmid","27829128"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43355"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1872-7697"],["dc.relation.issn","0167-8760"],["dc.title","Theta/beta neurofeedback in children with ADHD: Feasibility of a short-term setting and plasticity effects"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]