Krinner, Stefanie

[["dc.bibliographiccitation.firstpage","882"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Neuron"],["dc.bibliographiccitation.volume","84"],["dc.contributor.author","Imig, Cordelia"],["dc.contributor.author","Min, Sang-Won"],["dc.contributor.author","Krinner, Stefanie"],["dc.contributor.author","Arancillo, Marife"],["dc.contributor.author","Rosenmund, Christian"],["dc.contributor.author","Südhof, Thomas C."],["dc.contributor.author","Rhee, JeongSeop"],["dc.contributor.author","Brose, Nils"],["dc.contributor.author","Cooper, Benjamin H."],["dc.date.accessioned","2022-03-01T11:45:21Z"],["dc.date.available","2022-03-01T11:45:21Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1016/j.neuron.2014.11.003"],["dc.identifier.pii","S0896627314010034"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/103296"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-531"],["dc.relation.issn","0896-6273"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.subtype","erratum_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","416"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Neuron"],["dc.bibliographiccitation.lastpage","431"],["dc.bibliographiccitation.volume","84"],["dc.contributor.author","Imig, Cordelia"],["dc.contributor.author","Min, Sang-Won"],["dc.contributor.author","Krinner, Stefanie"],["dc.contributor.author","Arancillo, Marife"],["dc.contributor.author","Rosenmund, Christian"],["dc.contributor.author","Südhof, Thomas C."],["dc.contributor.author","Rhee, JeongSeop"],["dc.contributor.author","Brose, Nils"],["dc.contributor.author","Cooper, Benjamin H."],["dc.date.accessioned","2017-09-07T11:45:27Z"],["dc.date.available","2017-09-07T11:45:27Z"],["dc.date.issued","2014"],["dc.description.abstract","Synaptic vesicle docking, priming, and fusion at active zones are orchestrated by a complex molecular machinery. We employed hippocampal organotypic slice cultures from mice lacking key presynaptic proteins, cryofixation, and three-dimensional electron tomography to study the mechanism of synaptic vesicle docking in the same experimental setting, with high precision, and in a near-native state. We dissected previously indistinguishable, sequential steps in synaptic vesicle active zone recruitment (tethering) and membrane attachment (docking) and found that vesicle docking requires Munc13/CAPS family priming proteins and all three neuronal SNAREs, but not Synaptotagmin-1 or Complexins. Our data indicate that membrane-attached vesicles comprise the readily releasable pool of fusion-competent vesicles and that synaptic vesicle docking, priming, and trans-SNARE complex assembly are the respective morphological, functional, and molecular manifestations of the same process, which operates downstream of vesicle tethering by active zone components."],["dc.identifier.doi","10.1016/j.neuron.2014.10.009"],["dc.identifier.gro","3142032"],["dc.identifier.isi","000344167900020"],["dc.identifier.pmid","25374362"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/3790"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.eissn","1097-4199"],["dc.relation.issn","0896-6273"],["dc.title","The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]