Busch, Albert

[["dc.bibliographiccitation.firstpage","151"],["dc.bibliographiccitation.issue","1-4"],["dc.bibliographiccitation.journal","Plant Systematics and Evolution"],["dc.bibliographiccitation.lastpage","158"],["dc.bibliographiccitation.volume","290"],["dc.contributor.author","Bombosch, Andrea"],["dc.contributor.author","Wieneke, A."],["dc.contributor.author","Busch, Albert"],["dc.contributor.author","Jonas, R."],["dc.contributor.author","Hentschel, Joern"],["dc.contributor.author","Kreier, H.-P."],["dc.contributor.author","Shaw, B."],["dc.contributor.author","Shaw, A. Jonathan"],["dc.contributor.author","Heinrichs, Jochen"],["dc.date.accessioned","2018-11-07T08:36:31Z"],["dc.date.available","2018-11-07T08:36:31Z"],["dc.date.issued","2010"],["dc.description.abstract","We investigated the phylogeny of a Holarctic-Asian group of Frullania species, the Frullania dilatata-F. appalachiana F. eboracensis complex, using multiple accessions of morphologically circumscribed taxa and three molecular markers (nrITS region, cp DNA trnL-F and atpB-rbcL regions). Maximum parsimony and likelihood analyses indicated monophyly of morphologically defined taxa. Our phylogenies support a species rather than a subspecies concept within the complex, with four species in North America (F. appalachiana, F. eboracensis, F. parvistipula and F. virginica), and two species in Europe (F. dilatata and F. parvistipula). Accessions of F. dilatata from Southeast Europe and Asia are separated from other European accessions, indicating a former disjunct range of the species."],["dc.identifier.doi","10.1007/s00606-010-0357-3"],["dc.identifier.isi","000284289800013"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/5983"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18329"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","1615-6110"],["dc.relation.issn","0378-2697"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Narrow species concepts in the Frullania dilatata-appalachiana-eboracensis complex (Porellales, Jungermanniopsida): evidence from nuclear and chloroplast DNA markers"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","633"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Circulation Research"],["dc.bibliographiccitation.lastpage","644"],["dc.bibliographiccitation.volume","120"],["dc.contributor.author","Eken, Suzanne M."],["dc.contributor.author","Jin, Hong"],["dc.contributor.author","Chernogubova, Ekaterina"],["dc.contributor.author","Li, Yuhuang"],["dc.contributor.author","Simon, Nancy"],["dc.contributor.author","Sun, Changyan"],["dc.contributor.author","Korzunowicz, Greg"],["dc.contributor.author","Busch, Albert"],["dc.contributor.author","Bäcklund, Alexandra"],["dc.contributor.author","Österholm, Cecilia"],["dc.contributor.author","Razuvaev, Anton"],["dc.contributor.author","Renné, Thomas"],["dc.contributor.author","Eckstein, Hans Henning"],["dc.contributor.author","Pelisek, Jaroslav"],["dc.contributor.author","Eriksson, Per"],["dc.contributor.author","González Díez, María"],["dc.contributor.author","Perisic Matic, Ljubica"],["dc.contributor.author","Schellinger, Isabel N."],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Leeper, Nicholas J."],["dc.contributor.author","Hansson, Göran K."],["dc.contributor.author","Paulsson-Berne, Gabrielle"],["dc.contributor.author","Hedin, Ulf"],["dc.contributor.author","Maegdefessel, Lars"],["dc.date.accessioned","2020-12-10T18:37:59Z"],["dc.date.available","2020-12-10T18:37:59Z"],["dc.date.issued","2017"],["dc.description.abstract","Rationale: In the search for markers and modulators of vascular disease, microRNAs (miRNAs) have emerged as potent therapeutic targets. Objective: To investigate miRNAs of clinical interest in patients with unstable carotid stenosis at risk of stroke. Methods and Results: Using patient material from the BiKE (Biobank of Karolinska Endarterectomies), we profiled miRNA expression in patients with stable versus unstable carotid plaque. A polymerase chain reactionbased miRNA array of plasma, sampled at the carotid lesion site, identified 8 deregulated miRNAs (miR-15b, miR29c, miR-30c/d, miR-150, miR-191, miR-210, and miR-500). miR-210 was the most significantly downregulated miRNA in local plasma material. Laser capture microdissection and in situ hybridization revealed a distinct localization of miR-210 in fibrous caps. We confirmed that miR-210 directly targets the tumor suppressor gene APC (adenomatous polyposis coli), thereby affecting Wnt (Wingless-related integration site) signaling and regulating smooth muscle cell survival, as well as differentiation in advanced atherosclerotic lesions. Substantial changes in arterial miR-210 were detectable in 2 rodent models of vascular remodeling and plaque rupture. Modulating miR210 in vitro and in vivo improved fibrous cap stability with implications for vascular disease. Conclusions: An unstable carotid plaque at risk of stroke is characterized by low expression of miR-210. miR-210 contributes to stabilizing carotid plaques through inhibition of APC, ensuring smooth muscle cell survival. We present local delivery of miR-210 as a therapeutic approach for prevention of atherothrombotic vascular events."],["dc.identifier.doi","10.1161/CIRCRESAHA.116.309318"],["dc.identifier.eissn","1524-4571"],["dc.identifier.isi","000394446200016"],["dc.identifier.issn","0009-7330"],["dc.identifier.pmid","27895035"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77157"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","1524-4571"],["dc.relation.issn","0009-7330"],["dc.title","MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Busch, Albert"],["dc.date.accessioned","2021-06-28T06:28:46Z"],["dc.date.available","2021-06-28T06:28:46Z"],["dc.date.issued","2021-04-20"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/87307"],["dc.relation.conference","Die extreme Rechte – Bedrohungen und Gegenstrategien"],["dc.relation.date","2021-04-20"],["dc.relation.eventlocation","virtuell"],["dc.relation.eventorganizer","Georg-August-Universität Göttingen in Zusammenarbeit mit der Akademie der Wissenschaften Göttingen"],["dc.relation.multimedia","https://goedoc.uni-goettingen.de/docs/audio/ring2021-04-20.mp3"],["dc.relation.multimedia","https://www.youtube.com/watch?v=z8PNPuFXxp4"],["dc.title","Sprache und extreme Rechte"],["dc.type","lecture"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]