Wiegand, Annette E.

[["dc.bibliographiccitation.firstpage","1695"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","1700"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Maes, Mona Shaghayegh"],["dc.contributor.author","Kanzow, Philipp Clemens"],["dc.contributor.author","Biermann, Jana"],["dc.contributor.author","Leha, Andeas"],["dc.contributor.author","Hrasky, Valentina"],["dc.contributor.author","Wiegand, Annette"],["dc.creator.author","Maes MS"],["dc.creator.author","Kanzow P"],["dc.creator.author","Biermann J"],["dc.creator.author","Leha A"],["dc.creator.author","Hrasky V"],["dc.creator.author","Wiegand A"],["dc.date.accessioned","2021-08-30T07:48:17Z"],["dc.date.available","2021-08-30T07:48:17Z"],["dc.date.issued","2021-08-25"],["dc.description.abstract","Aim: Repeated dental treatment of patients with intellectual and/or physical disabilities under general anesthesia (GA) often becomes necessary. This study aimed to identify potential risk factors predictive of repeated dental treatment under general anesthesia.\r\nMaterials and methods: Data of adult patients with intellectual and/or physical disabilities receiving dental treatment under GA within a time period of 7 years were analyzed (n = 203, mean age: 41.0 ± 14.9 years). All patients received comprehensive dental treatment (professional tooth cleaning, periodontal therapy, composite restorations, and/or extractions); patients receiving extractions only for emergency dental care were not included as a second intervention for restorative treatment often followed. Demographic, anamnestic, oral health, and treatment factors were obtained from dental records. Duration of intervals without dental treatment under GA was assessed using Kaplan-Meier statistics. Potential predictive factors were tested using univariate and multivariate cox regression analyses.\r\nResults: Thirty-five patients (17.2%) received a second and five patients (2.5%) a third dental treatment under GA during that period. In the univariate analysis, patients' age, living situation, and nutrition were associated with repeated GA. In the multivariate Cox regression analysis, only nutrition remained significant. Risk for repeated treatment increased if patients were tube-fed (HR: 7.54, p = 0.001) or received pureed/liquid food (HR: 4.32, p = 0.007) compared to nutrition without limitation.\r\nConclusion: In adult patients with intellectual and/or physical disabilities, nutrition affects the risk for repeated dental treatment under GA.\r\nClinical relevance: Identification of risk factors making repeated dental treatment under GA of patients with intellectual and/or physical disabilities more likely is essential to adjust preventive measures."],["dc.identifier.doi","10.1007/s00784-021-04142-w"],["dc.identifier.pmcid","PMC8816736"],["dc.identifier.pmid","34432139"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88885"],["dc.identifier.url","https://link.springer.com/article/10.1007/s00784-021-04142-w"],["dc.language.iso","en"],["dc.relation.eissn","1436-3771"],["dc.relation.orgunit","Poliklinik für Präventive Zahnmedizin, Parodontologie und Kariologie"],["dc.relation.orgunit","Institut für Medizinische Statistik"],["dc.rights","CC BY 4.0"],["dc.subject.gro","Disability"],["dc.subject.gro","General anesthesia"],["dc.subject.gro","Restoration"],["dc.subject.gro","Extraction"],["dc.subject.gro","Kaplan–Meier statistics"],["dc.title","Risk factors for repeated general anesthesia for dental treatment of adult patients with intellectual and/or physical disabilities"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","4563"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","4569"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Maes, Mona Shaghayegh"],["dc.contributor.author","Kanzow, Philipp"],["dc.contributor.author","Hrasky, Valentina"],["dc.contributor.author","Wiegand, Annette"],["dc.date.accessioned","2021-04-14T08:30:39Z"],["dc.date.available","2021-04-14T08:30:39Z"],["dc.date.issued","2021-01-15"],["dc.description.abstract","Objectives: This study aimed to assess the survival of direct composite restorations placed under general anesthesia in adult patients with intellectual and/or physical disabilities.\r\nMaterials and methods: Survival of composite restorations placed under general anesthesia in adult patients with intellectual and/or physical disabilities was retrospectively analyzed. Failure was defined as the need for replacement of at least one surface of the original restoration or extraction of the tooth. Individual-, tooth-, and restoration-related factors were obtained from dental records. Five-year mean annual failure rate (mAFR) and median survival time were calculated (Kaplan-Meier statistics). The effect of potential risk factors on failure was tested using univariate log-rank tests and multivariate Cox-regression analysis (α = 5%).\r\nResults: A total of 728 restorations in 101 patients were included in the analysis. The survival after 5 years amounted to 67.7% (5-year mAFR: 7.5%) and median survival time to 7.9 years. Results of the multivariate Cox-regression analysis revealed physical disability (HR: 50.932, p = 0.001) and combined intellectual/physical disability (HR: 3.145, p = 0.016) compared with intellectual disability only, presence of a removable partial denture (HR: 3.013, p < 0.001), and restorations in incisors (HR: 2.281, p = 0.013) or molars (HR: 1.693, p = 0.017) compared with premolars to increase the risk for failure.\r\nConclusion: Composite restorations placed under general anesthesia in adult patients with intellectual and/or physical disabilities showed a reasonable longevity as 67.7% survived at least 5 years.\r\nClinical relevance: Survival of composite restorations depends on risk factors that need to be considered when planning restorative treatment in patients with intellectual and/or physical disabilities. NCT04407520."],["dc.identifier.doi","10.1007/s00784-020-03770-y"],["dc.identifier.pmcid","PMC8310491"],["dc.identifier.pmid","33449193"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17859"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83321"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1436-3771"],["dc.relation.issn","1432-6981"],["dc.relation.orgunit","Poliklinik für Präventive Zahnmedizin, Parodontologie und Kariologie"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.gro","Composite"],["dc.subject.gro","Disability"],["dc.subject.gro","Kaplan-Meier statistics"],["dc.subject.gro","Longevity"],["dc.subject.gro","Restoration"],["dc.title","Survival of direct composite restorations placed under general anesthesia in adult patients with intellectual and/or physical disabilities"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1623"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","1636"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Splieth, C. H."],["dc.contributor.author","Kanzow, Philipp"],["dc.contributor.author","Wiegand, Annette"],["dc.contributor.author","Schmoeckel, Julian"],["dc.contributor.author","Jablonski-Momeni, Anahita"],["dc.date.accessioned","2020-05-20T13:09:17Z"],["dc.date.accessioned","2020-05-22T07:55:56Z"],["dc.date.available","2020-05-20T13:09:17Z"],["dc.date.available","2020-05-22T07:55:56Z"],["dc.date.issued","2020-04-18"],["dc.description.abstract","Objectives: For an ORCA/EFCD consensus, this systematic review assessed the question \"How to intervene in the caries process in proximal caries in adolescents and adults\".\r\nMaterial and methods: Separating between the management of initial and cavitated proximal caries lesions, Medline via PubMed was searched regarding non-operative/non-invasive, minimally/micro-invasive and restorative treatment. First priority was systematic reviews or randomized controlled trials (RCTs), otherwise cohort studies. After extraction of data, the potential risk of bias was estimated depending on the study type, and the emerging evidence for conclusions was graded.\r\nResults: Regarding non-invasive/non-operative care (NOC), no systematic reviews or RCTs were found. In cohort studies (n = 12) with a low level of evidence, NOC like biofilm management and fluoride was associated with a low proportion and slow speed of progression of initial proximal lesions. Minimally/micro-invasive (MI) treatments such as proximal sealants or resin infiltration (four systematic reviews/meta-analyses) were effective compared with a non-invasive/placebo control at a moderate level of evidence. Data on restorative treatment came with low evidence (5 systematic reviews, 13 RCTs); with the limitation of no direct comparative studies, sample size-weighted mean annual failure rates of class II restorations varied between 1.2 (bulk-fill composite) and 3.8% (ceramic). Based on one RCT, class II composite restorations may show a higher risk of failure compared with amalgam.\r\nConclusions: Proximal caries lesions can be managed successfully with non-operative, micro-invasive and restorative treatment according to lesion stage and caries activity.\r\nClinical relevance: Proximal caries treatment options like non-operative, micro-invasive and restorative care should be considered individually."],["dc.identifier.doi","10.1007/s00784-020-03201-y"],["dc.identifier.pmid","32306093"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17319"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/65636"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/65701"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1436-3771"],["dc.relation.issn","1432-6981"],["dc.relation.orgunit","Poliklinik für Präventive Zahnmedizin, Parodontologie und Kariologie"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.gro","Caries"],["dc.subject.gro","Micro-invasive"],["dc.subject.gro","Minimally invasive"],["dc.subject.gro","Non-operative"],["dc.subject.gro","Proximal"],["dc.subject.gro","Restoration"],["dc.title","How to intervene in the caries process: proximal caries in adolescents and adults-a systematic review and meta-analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]