Schill, Tillmann

[["dc.bibliographiccitation.firstpage","528"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Molecular Cancer Research"],["dc.bibliographiccitation.lastpage","542"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Amschler, Katharina"],["dc.contributor.author","Kossmann, Eugen"],["dc.contributor.author","Erpenbeck, Luise"],["dc.contributor.author","Kruss, Sebastian"],["dc.contributor.author","Schill, Tillmann"],["dc.contributor.author","Schön, Margarete"],["dc.contributor.author","Möckel, Sigrid M.C."],["dc.contributor.author","Spatz, Joachim P."],["dc.contributor.author","Schön, Michael P."],["dc.date.accessioned","2020-12-10T18:37:47Z"],["dc.date.available","2020-12-10T18:37:47Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1158/1541-7786.MCR-17-0272"],["dc.identifier.eissn","1557-3125"],["dc.identifier.issn","1541-7786"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77091"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Nanoscale Tuning of VCAM-1 Determines VLA-4–Dependent Melanoma Cell Plasticity on RGD Motifs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","231"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","240"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Forkel, Susann"],["dc.contributor.author","Cevik, Naciye"],["dc.contributor.author","Schill, Tillmann"],["dc.contributor.author","Worm, Margitta"],["dc.contributor.author","Mahler, Vera"],["dc.contributor.author","Weisshaar, Elke"],["dc.contributor.author","Vieluf, Dieter"],["dc.contributor.author","Pfützner, Wolfgang"],["dc.contributor.author","Löffler, Harald"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Geier, Johannes"],["dc.contributor.author","Buhl, Timo"],["dc.date.accessioned","2021-04-14T08:30:05Z"],["dc.date.available","2021-04-14T08:30:05Z"],["dc.date.issued","2021"],["dc.description.abstract","Summary Background The association of atopic dermatitis (AD) and allergic contact dermatitis has been a matter of considerable uncertainty. Study results range from lack of any association to increased sensitization for multiple allergens, but fail to identify consistent allergen associations. Objective We studied a large patch test cohort of patients stratified by their atopic skin diathesis using the Erlangen Atopy Score (EAS), independent of active skin disease. Methods Retrospective multi‐center data analysis from five departments of dermatology in Germany with 4,509 patients. Patients were grouped as “no atopic skin diathesis” (n = 2,165) and “atopic skin diathesis” (n = 1,743), according to EAS. Results Significantly more individuals with atopic skin diathesis showed at least one positive patch test reaction to the baseline series compared to individuals without atopic skin diathesis (49.1 % vs. 38.3 %). In logistic regression analyses, atopic skin diathesis was associated with a significantly higher risk of sensitization to methylchloroisothiazolinone/methylisothiazolinone (OR 2.383) and methylisothiazolinone (OR 1.891), thiuram mix (OR 1.614), as well as nickel (OR 1.530), cobalt (OR 1.683), and chromium (OR 2.089). Conclusions Atopic skin diathesis proved to be the most important intrinsic risk factor for contact sensitization to few, specific allergens. Past or present AD was a less relevant variable."],["dc.identifier.doi","10.1111/ddg.14341"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83096"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.rights","This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes."],["dc.title","Atopic skin diathesis rather than atopic dermatitis is associated with specific contact allergies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Schill, Tillmann"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Thoms, Kai Martin"],["dc.date.accessioned","2018-11-07T09:05:25Z"],["dc.date.available","2018-11-07T09:05:25Z"],["dc.date.issued","2012"],["dc.format.extent","E12"],["dc.identifier.isi","000309186700046"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25309"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0379"],["dc.title","P11-Combined Dye- and Neodym-YAG-Laser Therapy for long-standing size-progressive tumorous Lip-Hemangioma"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","91"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.lastpage","98"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Schill, Tillmann"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Pletz, Nadin"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, Margarete"],["dc.date.accessioned","2018-11-07T09:14:03Z"],["dc.date.available","2018-11-07T09:14:03Z"],["dc.date.issued","2012"],["dc.description.abstract","Given that metastasized melanoma is a fatal disease in most cases, it is tempting to develop strategies to a priori prevent metastasis. We have stimulated the pulmonary innate immune system by macrophage-activating lipopeptide-2 (MALP-2), a specific agonist at Toll-like receptor (TLR) 2/6, and investigated its impact on experimental melanoma metastasis. In C57BL/6 mice, intratracheal application of MALP-2 induced a profound influx of neutrophils and macrophages into the lung, which peaked after 24 h (sixfold increase) and returned to baseline within 72 h. Further analysis revealed that MALP-2 also markedly induced VCAM-1 expression on pulmonary blood vessels. In vitro experiments demonstrated that this adhesion molecule mediates binding of B16F10 melanoma cells. Furthermore, in vivo or in vitro treatment with MALP-2 did not significantly affect the ability of immune cells to lyse melanoma cells. As a consequence, notwithstanding the profound pulmonary immune response induction and in contrast to conclusions drawn from some previous publications, the net extent of experimental metastasis did not change significantly, regardless of the application regimen of MALP-2 prior to, concomitant with or after tumor cell inoculation. Melanoma cells stably transfected with green fluorescent protein allowed tracking of early events after tumor cell dissemination and showed that MALP-2-mediated TLR2/6 activation did not interfere with pulmonary melanoma cell arrest. Likewise, boosting the immune induction after establishment of metastases did not change the clinical outcome. These unexpected results vividly counsel caution regarding predictions of immunomodulating therapies, as multiple intertwined effects may influence the net outcome."],["dc.identifier.doi","10.1111/j.1600-0625.2011.01386.x"],["dc.identifier.isi","000298917000003"],["dc.identifier.pmid","22044500"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27311"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0906-6705"],["dc.title","Stimulation of pulmonary immune responses by the TLR2/6 agonist MALP-2 and effect on melanoma metastasis to the lung"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","82"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Advances in skin & wound care"],["dc.bibliographiccitation.lastpage","88"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Schill, Tillmann"],["dc.contributor.author","Hartmann, Franziska"],["dc.contributor.author","Grönemeyer, Lisa-Lena"],["dc.contributor.author","Holzkamp, Ricarda"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Thoms, Kai-Martin"],["dc.date.accessioned","2020-12-10T18:19:46Z"],["dc.date.available","2020-12-10T18:19:46Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1097/01.ASW.0000527965.64870.03"],["dc.identifier.issn","1527-7941"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75372"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Testing Elevated Protease Activity"],["dc.title.alternative","Prospective Analysis of 160 Wounds"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]