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  • 2004Journal Article
    [["dc.bibliographiccitation.firstpage","619"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Psychiatric Research"],["dc.bibliographiccitation.lastpage","635"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Wagner, Thilo"],["dc.contributor.author","Krampe, Henning"],["dc.contributor.author","Stawicki, Sabina"],["dc.contributor.author","Reinhold, Jennifer"],["dc.contributor.author","Jahn, Henriette"],["dc.contributor.author","Mahlke, Kristin"],["dc.contributor.author","Barth, Ulrike"],["dc.contributor.author","Sieg, Sonja"],["dc.contributor.author","Maul, Oliver"],["dc.contributor.author","Galwas, Claudia"],["dc.contributor.author","Aust, Carlotta"],["dc.contributor.author","Kröner-Herwig, Birgit"],["dc.contributor.author","Brunner, Edgar"],["dc.contributor.author","Poser, Wolfgang"],["dc.contributor.author","Henn, Fritz"],["dc.contributor.author","Rüther, Eckart"],["dc.contributor.author","Ehrenreich, Hannelore"],["dc.date.accessioned","2017-09-07T11:46:24Z"],["dc.date.available","2017-09-07T11:46:24Z"],["dc.date.issued","2004"],["dc.description.abstract","It is far from clear how comorbidity changes during alcoholism treatment. This study investigates: (1) the course of comorbid Axis I disorders in chronic alcoholics over 2 years of controlled abstinence in the outpatient long-term intensive therapy for alcoholics (OLITA) and (2) the effect of comorbid Axis I and II disorders in this group of patients on subsequent drinking outcome over a four-year follow-up. This prospective treatment study evaluates psychiatric variables of 89 severely affected chronic alcohol dependent patients on admission (t1), month 6 (t2), 12 (t3) and 24 (t4). Drinking outcomes have been analyzed from 1998 to 2002. On admission, 61.8% of the patients met criteria for a comorbid Axis I disorder, 63.2% for a comorbid personality disorder. Axis I disorders remit from t1 (59.0% ill), t2 (38.5%), t3 (28.2%) to t4 (12.8%) (p<0.0001). Anxiety disorders remit more slowly from t1 (43.6%) to t3 (20.5%, p=0.0086), whereas mood disorders remit early between t1 (23.1%) and t2 (5.1%, p=0.0387) with a slight transient increase at t3 (10.3%). During the four-year follow-up, the cumulative probability of not having relapsed amounts to 0.59. Two predictors have a strong negative impact on abstinence probability: number of inpatient detoxifications (p=0.0013) and personality disorders (p=0.0106). The present study demonstrates a striking remission of comorbid Axis I disorders upon abstinence during comprehensive long-term outpatient alcoholism treatment. The presence of an Axis II rather than an Axis I disorder on admission strongly predicts drinking outcome over a four-year follow-up"],["dc.identifier.doi","10.1016/j.jpsychires.2004.04.007"],["dc.identifier.gro","3150506"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7278"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.issn","0022-3956"],["dc.subject","Outpatient alcoholism treatment; Chronic alcohol dependence; Prognosis; Comorbid personality disorders; Chronicity; Chronic psychiatric illness"],["dc.title","Substantial decrease of psychiatric comorbidity in chronic alcoholics upon integrated outpatient treatment - results of a prospective study"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","unknown"],["dspace.entity.type","Publication"]]
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