Now showing 1 - 4 of 4
  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","137"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","142"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Brandes, Ivo Florian"],["dc.contributor.author","Mueller, C."],["dc.contributor.author","Perl, Tal Naggan"],["dc.contributor.author","Russo, Sebastian Giuseppe"],["dc.contributor.author","Bauer, M."],["dc.contributor.author","Braeuer, Anselm"],["dc.date.accessioned","2018-11-07T09:28:28Z"],["dc.date.available","2018-11-07T09:28:28Z"],["dc.date.issued","2013"],["dc.description.abstract","Perioperative hypothermia is a common complication of general anesthesia and occurs in up to 50 % of patients during ear, nose and throat (ENT) surgery. In this prospective, randomized controlled study the hypothesis that a new conductive warming blanket (BarrierA (R) EasyWarmA (R), Molnlycke Health Care Erkrath, Germany) is better in reducing the incidence of perioperative hypothermia in ENT surgery than insulation with a conventional hospital duvet alone was tested. After approval of the local ethics committee and written informed consent 80 patients with a planned procedure time between 1 and 3 h were recruited. Anesthesia was induced and maintained using propofol, remifentanil and rocuronium and the core temperature was measured using an esophageal temperature probe. Patients in the study group were warmed at least 30 min prior to induction of anesthesia using the novel warming blanket (BarrierA (R) EasyWarmA (R)) and patients in the control group were insulated with a standard hospital duvet. Data were tested using Fisher's exact test, Student's t-test or the Mann-Whitney U-test as appropriate. Time-dependent changes in core temperature were evaluated using repeated measures analysis of variance (ANOVA) and post hoc Scheff,'s test. Results are expressed as mean +/- SD or as median and interquartile range (IQR) as appropriate. A p < 0.05 was considered to be statistically significant. The ANOVA did not identify a significantly higher core temperature in the study group at any time point. Furthermore, Fisher's exact test showed no differences in the incidence of intraoperative (12 out of 29 versus 10 out of 32 patients, p = 0.44) or postoperative hypothermia (12 out of 29 versus 9 out of 32 patients, p = 0.30) between the groups. No adverse effects were observed. In the studied patient group the new conductive warming blanket (BarrierA (R) EasyWarmA (R)) showed no superiority compared to conventional thermal insulation alone."],["dc.identifier.doi","10.1007/s00101-013-2140-7"],["dc.identifier.isi","000315334300009"],["dc.identifier.pmid","23404220"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30783"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0003-2417"],["dc.title","Efficacy of a novel warming blanket. Prospective randomized trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.firstpage","406"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","414"],["dc.bibliographiccitation.volume","63"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Brandes, Ivo Florian"],["dc.contributor.author","Perl, Tal Naggan"],["dc.contributor.author","Wetz, Anna J."],["dc.contributor.author","Bauer, M."],["dc.date.accessioned","2018-11-07T09:40:39Z"],["dc.date.available","2018-11-07T09:40:39Z"],["dc.date.issued","2014"],["dc.description.abstract","Prewarming is a useful and effective measure to reduce perioperative hypothermia. Due to A 23(3) of the German Infektionsschutzgesetz (Gesetz zur Verhutung und Bekampfung von Infektionskrankheiten beim Menschen, Infection Act, act on protection and prevention of infectious diseases in man) and the recommendations of the Hospital Hygiene and Infection Prevention Committee of the Robert Koch Institute, implementation of prewarming is clearly recommended. There are several technically satisfactory and practicable devices available allowing prewarming on the normal hospital ward, in the preoperative holding area or in the induction room of the operating theater (OR) The implementation of prewarming requires additional equipment and training of staff. Using a locally adapted concept for the implementation of prewarming does not lead to inefficiency in the perioperative process. In contrast, the implementation can help to achieve stable arrival times for patients in the OR."],["dc.identifier.doi","10.1007/s00101-014-2316-9"],["dc.identifier.isi","000336326100006"],["dc.identifier.pmid","24691948"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33550"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-055X"],["dc.relation.issn","0003-2417"],["dc.title","Prewarming. Yesterday's luxury, today's minimum requirements"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.firstpage","874"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","883"],["dc.bibliographiccitation.volume","64"],["dc.contributor.author","Bauer, M."],["dc.contributor.author","Riech, Sebastian"],["dc.contributor.author","Brandes, Ivo Florian"],["dc.contributor.author","Waeschle, Reiner M."],["dc.date.accessioned","2018-11-07T09:49:29Z"],["dc.date.available","2018-11-07T09:49:29Z"],["dc.date.issued","2015"],["dc.description.abstract","The quality assurance of care and patient safety, with increasing cost pressure and performance levels is of major importance in the high-risk and high cost area of the operating room (OR). Standard operating procedures (SOP) are an established tool for structuring and standardization of the clinical treatment pathways and show multiple benefits for quality assurance and process optimization. An internal project was initiated in the department of anesthesiology and a continuous improvement process was carried out to build up a comprehensive SOP library. In the first step the spectrum of procedures in anesthesiology was transferred to PDF-based SOPs. The further development to an app-based SOP library (Aesculapp) was due to the high resource expenditure for the administration and maintenance of the large PDF-based SOP collection and to deficits in the mobile availability. The next developmental stage, the SOP healthcare information assistant (SOPHIA) included a simplified and advanced update feature, an archive feature previously missing and notably the possibility to share the SOP library with other departments including the option to adapt each SOP to the individual situation. A survey of the personnel showed that the app-based allocation of SOPs (Aesculapp, SOPHIA) had a higher acceptance than the PDF-based developmental stage SOP form. The SOP management system SOPHIA combines the benefits of the forerunner version Aesculapp with improved options for intradepartmental maintenance and administration of the SOPs and the possibility of an export and editing function for interinstitutional exchange of SOPs."],["dc.identifier.doi","10.1007/s00101-015-0074-y"],["dc.identifier.isi","000364972600009"],["dc.identifier.pmid","26481389"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35518"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-055X"],["dc.relation.issn","0003-2417"],["dc.title","Advantages and disadvantages of different methods for the implementation and the support of standard operating procedures. From PDF files to an app- and webbased SOP management system"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.firstpage","1397"],["dc.bibliographiccitation.issue","15"],["dc.bibliographiccitation.journal","New England Journal of Medicine"],["dc.bibliographiccitation.lastpage","1407"],["dc.bibliographiccitation.volume","373"],["dc.contributor.author","Meybohm, Patrick"],["dc.contributor.author","Bein, B."],["dc.contributor.author","Brosteanu, Oana"],["dc.contributor.author","Cremer, Jochen"],["dc.contributor.author","Gruenewald, M."],["dc.contributor.author","Stoppe, C."],["dc.contributor.author","Coburn, Marc"],["dc.contributor.author","Schaelte, Gereon"],["dc.contributor.author","Boening, Andreas"],["dc.contributor.author","Niemann, B."],["dc.contributor.author","Roesner, Jan"],["dc.contributor.author","Kletzin, Frank"],["dc.contributor.author","Strouhal, Ulrich"],["dc.contributor.author","Reyher, Christian"],["dc.contributor.author","Laufenberg-Feldmann, R."],["dc.contributor.author","Ferner, M."],["dc.contributor.author","Brandes, Ivo Florian"],["dc.contributor.author","Bauer, M."],["dc.contributor.author","Stehr, Sebastian N."],["dc.contributor.author","Kortgen, A."],["dc.contributor.author","Wittmann, M."],["dc.contributor.author","Baumgarten, G."],["dc.contributor.author","Meyer-Treschan, T."],["dc.contributor.author","Kienbaum, P."],["dc.contributor.author","Heringlake, Matthias"],["dc.contributor.author","Schoen, Julika"],["dc.contributor.author","Sander, M."],["dc.contributor.author","Treskatsch, S."],["dc.contributor.author","Smul, Thorsten"],["dc.contributor.author","Wolwender, E."],["dc.contributor.author","Schilling, Thomas"],["dc.contributor.author","Fuernau, G."],["dc.contributor.author","Hasenclever, Dirk"],["dc.contributor.author","Zacharowski, Kai"],["dc.date.accessioned","2018-11-07T09:50:18Z"],["dc.date.available","2018-11-07T09:50:18Z"],["dc.date.issued","2015"],["dc.description.abstract","BACKGROUND Remote ischemic preconditioning (RIPC) is reported to reduce biomarkers of ischemic and reperfusion injury in patients undergoing cardiac surgery, but uncertainty about clinical outcomes remains. METHODS We conducted a prospective, double-blind, multicenter, randomized, controlled trial involving adults who were scheduled for elective cardiac surgery requiring cardiopulmonary bypass under total anesthesia with intravenous propofol. The trial compared upper-limb RIPC with a sham intervention. The primary end point was a composite of death, myocardial infarction, stroke, or acute renal failure up to the time of hospital discharge. Secondary end points included the occurrence of any individual component of the primary end point by day 90. RESULTS A total of 1403 patients underwent randomization. The full analysis set comprised 1385 patients (692 in the RIPC group and 693 in the sham-RIPC group). There was no significant between-group difference in the rate of the composite primary end point (99 patients [14.3%] in the RIPC group and 101 [14.6%] in the sham-RIPC group, P = 0.89) or of any of the individual components: death (9 patients [1.3%] and 4 [0.6%], respectively; P = 0.21), myocardial infarction (47 [6.8%] and 63 [9.1%], P = 0.12), stroke (14 [2.0%] and 15 [2.2%], P = 0.79), and acute renal failure (42 [6.1%] and 35 [5.1%], P = 0.45). The results were similar in the per-protocol analysis. No treatment effect was found in any subgroup analysis. No significant differences between the RIPC group and the sham-RIPC group were seen in the level of troponin release, the duration of mechanical ventilation, the length of stay in the intensive care unit or the hospital, new onset of atrial fibrillation, and the incidence of postoperative delirium. No RIPC-related adverse events were observed. CONCLUSIONS Upper-limb RIPC performed while patients were under propofol-induced anesthesia did not show a relevant benefit among patients undergoing elective cardiac surgery."],["dc.identifier.doi","10.1056/NEJMoa1413579"],["dc.identifier.isi","000362372800006"],["dc.identifier.pmid","26436208"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13833"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35685"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Massachusetts Medical Soc"],["dc.relation.issn","1533-4406"],["dc.relation.issn","0028-4793"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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