Zapf, Antonia

[["dc.bibliographiccitation.firstpage","317"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Cells Tissues Organs"],["dc.bibliographiccitation.lastpage","326"],["dc.bibliographiccitation.volume","189"],["dc.contributor.author","Drengk, Anja"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Stuermer, Ewa Klara"],["dc.contributor.author","Stuermer, Klaus Michael"],["dc.contributor.author","Frosch, Karl-Heinz"],["dc.date.accessioned","2018-11-07T08:34:01Z"],["dc.date.available","2018-11-07T08:34:01Z"],["dc.date.issued","2009"],["dc.description.abstract","Background/Aims: Autologous chondrocyte (CC) transplantation has the disadvantages of requiring two surgical interventions and in vitro expansion of cells, implying the risk of cellular dedifferentiation. Our clinical aim is to develop a one-step procedure for autologous CC transplantation, i.e. harvesting, isolation and reimplantation of CC performed in one single surgical procedure. Platelet-rich plasma (PRP) is a source of autologous growth factors reported to have mitogenic effects. The objective of this study was to test the influence of PRP as an autologous scaffold on freshly isolated CC and mesenchymal stem cells (MSC). Methods: CC and MSC were subjected to two- or three-dimensional (3D) growth systems, either with or without PRP. Chondrogenic differentiation was determined via quantification of collagen type II mRNA and immunohistochemical staining. Results: We observed a proliferative effect for MSCs exposed to PRP in monolayer culture and an increase in the expression of chondrogenic markers when cells are exposed to a 3D environment. CCs exposed to PRP show a decrease in the chondrogenic phenotype with increasing proliferative activity. Conclusion: PRP has a proliferative effect on CCs and MSCs. In a one-step procedure for autologous CC transplantation, this might be an advantage over other scaffold materials, but confirmation in in vivo studies is required. Copyright (C) 2008 S. Karger AG, Basel"],["dc.identifier.doi","10.1159/000151290"],["dc.identifier.isi","000265178600002"],["dc.identifier.pmid","18689989"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9312"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17722"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.relation.issn","1422-6405"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Influence of Platelet-Rich Plasma on Chondrogenic Differentiation and Proliferation of Chondrocytes and Mesenchymal Stem Cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1980"],["dc.bibliographiccitation.issue","14"],["dc.bibliographiccitation.journal","Statistics in Medicine"],["dc.bibliographiccitation.lastpage","1998"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Asendorf, Thomas"],["dc.contributor.author","Anten, Christoph"],["dc.contributor.author","Mütze, Tobias"],["dc.contributor.author","Friede, Tim"],["dc.date.accessioned","2021-04-14T08:26:15Z"],["dc.date.available","2021-04-14T08:26:15Z"],["dc.date.issued","2020"],["dc.description.abstract","In randomized clinical trials, it is standard to include baseline variables in the primary analysis as covariates, as it is recommended by international guidelines. For the study design to be consistent with the analysis, these variables should also be taken into account when calculating the sample size to appropriately power the trial. Because assumptions made in the sample size calculation are always subject to some degree of uncertainty, a blinded sample size reestimation (BSSR) is recommended to adjust the sample size when necessary. In this article, we introduce a BSSR approach for count data outcomes with baseline covariates. Count outcomes are common in clinical trials and examples include the number of exacerbations in asthma and chronic obstructive pulmonary disease, relapses, and scan lesions in multiple sclerosis and seizures in epilepsy. The introduced methods are based on Wald and likelihood ratio test statistics. The approaches are illustrated by a clinical trial in epilepsy. The BSSR procedures proposed are compared in a Monte Carlo simulation study and shown to yield power values close to the target while not inflating the type I error rate."],["dc.identifier.doi","10.1002/sim.8525"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81880"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1097-0258"],["dc.relation.issn","0277-6715"],["dc.rights","This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited."],["dc.title","Blinded sample size reestimation for negative binomial regression with baseline adjustment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0135439"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Brunkhorst, Lena Caroline"],["dc.contributor.author","Fichtner, Alexander"],["dc.contributor.author","Hoecker, Britta"],["dc.contributor.author","Burmeister, Greta"],["dc.contributor.author","Ahlenstiel-Grunow, Thurid"],["dc.contributor.author","Krupka, Kai"],["dc.contributor.author","Bald, Martin"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Toenshoff, Burkhard"],["dc.contributor.author","Pape, Lars"],["dc.date.accessioned","2018-11-07T09:51:29Z"],["dc.date.available","2018-11-07T09:51:29Z"],["dc.date.issued","2015"],["dc.description.abstract","Introduction Data on the efficacy and safety of everolimus in pediatric renal transplantation compared to other immunosuppressive regimens are scarce. Patients/Methods We therefore performed a multicenter, observational, matched cohort study over 4 years post-transplant in 35 patients on everolimus plus low-dose cyclosporine, who were matched (1: 2) with a control group of 70 children receiving a standard-dose calcineurin-inhibitor-and mycophenolate mofetil-based regimen. Results Corticosteroids were withdrawn in 83% in the everolimus vs. 39% in the control group (p<0.001). Patient and graft survival were comparable. The rate of biopsy-proven acute rejection episodes Banff score >= IA during the first year post-transplant was 6% in the everolimus vs. 13% in the control group (p = 0.23). The rate of de novo donor-specific HLA antibodies (11% in everolimus, 18% in controls) was comparable (p = 0.55). At 4 years post-transplant, mean eGFR in the everolimus group was 56 +/- 33 ml/min per 1.73 m(2) vs. 63 +/- 22 ml/min per 1.73 m(2) in the control group (p = 0.14). Everolimus therapy was associated with less BK polyomavirus replication (3% vs. 17% in controls; p = 0.04), but with a higher percentage of arterial hypertension and more hyperlipidemia (p<0.001). Conclusion In pediatric renal transplantation, an everolimus-based regimen with low-dose cyclosporine yields comparable four year results as a standard regimen, but with a different side effect profile."],["dc.description.sponsorship","Novartis Germany, Nuremberg, Germany"],["dc.identifier.doi","10.1371/journal.pone.0135439"],["dc.identifier.isi","000361800700005"],["dc.identifier.pmid","26407177"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12219"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35925"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Efficacy and Safety of an Everolimus- vs. a Mycophenolate Mofetil-Based Regimen in Pediatric Renal Transplant Recipients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","60"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Nursing"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Pickenbrock, Heidrun"],["dc.contributor.author","Ludwig, Vera U."],["dc.contributor.author","Zapf, Antonia"],["dc.date.accessioned","2020-12-10T18:38:57Z"],["dc.date.available","2020-12-10T18:38:57Z"],["dc.date.issued","2017"],["dc.description.abstract","Abstract Background Decubitus ulcers are associated with a burden for the patients and cause enormous costs. One of the reasons for the development of decubitus is prolonged exposure to pressure. The aim of this pilot study was to examine the pressure distribution of healthy individuals either positioned in Positioning in Neutral (LiN) or conventional positioning (CON). Methods Four healthy participants were positioned in a supine, 30° degree side lying and 90° side lying position both in LiN and CON. A thousand pressure sensors in a mattress enabled a visual presentation of low, medium and high pressure on a screen. This presentation was processed by Photoshop in order to count the pixels representing the total support pressure surface and the pressure intensity. Results LiN showed, on average, a smaller surface with measurable pressure compared to CON (46,293 versus 64,090 pixels). The areas of medium pressure were comparable. Mean areas of low and high pressure were both smaller in LiN as compared to CON (low: 8315 versus 22,790 pixels; high: 3744 versus 7277 pixels). Conclusion The results of this pilot study indicate that LiN is suitable for pressure sore prophylaxis because LiN showed less support surface and less maximum pressure as compared to CON."],["dc.identifier.doi","10.1186/s12912-017-0253-z"],["dc.identifier.eissn","1472-6955"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15126"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77492"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","BioMed Central"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Support pressure distribution for positioning in neutral versus conventional positioning in the prevention of decubitus ulcers: a pilot study in healthy participants"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","UNSP 847"],["dc.bibliographiccitation.journal","Frontiers in Human Neuroscience"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Neufeld, Janina"],["dc.contributor.author","Roy, Mandy"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Sinke, Christopher"],["dc.contributor.author","Emrich, Hinderk M."],["dc.contributor.author","Prox-Vagedes, Vanessa"],["dc.contributor.author","Dillo, Wolfgang"],["dc.contributor.author","Zedler, Markus"],["dc.date.accessioned","2018-11-07T09:16:36Z"],["dc.date.available","2018-11-07T09:16:36Z"],["dc.date.issued","2013"],["dc.description.abstract","There is increasing evidence from case reports that synesthesia is more common in individuals with autism spectrum conditions (ASC). Further, genes related to synesthesia have also been found to be linked to ASC and, similar to synaesthetes, individuals with ASC show altered brain connectivity and unusual brain activation during sensory processing. However, up to now a systematic investigation of whether synesthesia is more common in ASC patients is missing. The aim of the current pilot study was to test this hypothesis by investigating a group of patients diagnosed with Asperger Syndrome (AS) using questionnaires and standard consistency tests in order to classify them as grapheme-color synaesthetes. The results indicate that there are indeed many more grapheme-color synaesthetes among AS patients. This finding is discussed in relation to different theories regarding the development of synesthesia as well as altered sensory processing in autism."],["dc.description.sponsorship","DFG [SFB 936/A4]"],["dc.identifier.doi","10.3389/fnhum.2013.00847"],["dc.identifier.isi","000328161600001"],["dc.identifier.pmid","24367321"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10701"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27970"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Frontiers Research Foundation"],["dc.relation.issn","1662-5161"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","Is synesthesia more common in patients with Asperger syndrome?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1576"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Leukemia"],["dc.bibliographiccitation.lastpage","1586"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Chapuy, Björn"],["dc.contributor.author","Koch, R."],["dc.contributor.author","Radunski, Ulf"],["dc.contributor.author","Corsham, Sabrina"],["dc.contributor.author","Cheong, Naeun"],["dc.contributor.author","Inagaki, Nobuya"],["dc.contributor.author","Ban, N."],["dc.contributor.author","Wenzel, D."],["dc.contributor.author","Reinhardt, D."],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Schweyer, Stefan"],["dc.contributor.author","Kosari, F."],["dc.contributor.author","Klapper, Wolfram"],["dc.contributor.author","Truemper, Lorenz H."],["dc.contributor.author","Wulf, Gerald G."],["dc.date.accessioned","2018-11-07T11:12:37Z"],["dc.date.available","2018-11-07T11:12:37Z"],["dc.date.issued","2008"],["dc.description.abstract","Multidrug resistance (MDR) seriously limits the efficacy of chemotherapy in patients with cancer and leukemia. Active transport across membranes is essential for such cellular drug resistance, largely provided by ATP-binding cassette (ABC) transport proteins. Intracellular drug sequestration contributes to MDR; however, a genuine intracellular ABC transport protein with MDR function has not yet been identified. Analyzing the intrinsic drug efflux capacity of leukemic stem cells, we found the ABC transporter A3 (ABCA3) to be expressed consistently in acute myeloid leukemia (AML) samples. Greater expression of ABCA3 is associated with unfavorable treatment outcome, and in vitro, elevated expression induces resistance toward a broad spectrum of cytostatic agents. ABCA3 remains localized within the limiting membranes of lysosomes and multivesicular bodies, in which cytostatics are efficiently sequestered. In addition to AML, we also detected ABCA3 in a panel of lymphohematopoietic tissues and transformed cell lines. In conclusion, we identified subcellular drug sequestration mediated by the genuinely intracellular ABCA3 as being a clinically relevant mechanism of intrinsic MDR."],["dc.identifier.doi","10.1038/leu.2008.103"],["dc.identifier.isi","000258413400013"],["dc.identifier.pmid","18463677"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6063"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53706"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0887-6924"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","288"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Clinical Rehabilitation"],["dc.bibliographiccitation.lastpage","293"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Pickenbrock, Heidrun Maria"],["dc.contributor.author","Diel, Andrea"],["dc.contributor.author","Zapf, Antonia"],["dc.date.accessioned","2018-11-07T10:17:48Z"],["dc.date.available","2018-11-07T10:17:48Z"],["dc.date.issued","2016"],["dc.description.abstract","Objective: Within a sample of acute post-stroke patients, to compare the score on the Berg Balance Scale and the Static Balance Test for validity, inter-rater reliability, and the expenditure of time. Design: Prospective, intra-individual, cross-sectional evaluation study. Setting: Acute stroke unit of a university hospital in Germany. Participants: A total of 53 patients with acute stroke who did not have other pathology affecting their balance. Main outcome measure: For intra-individual comparisons of the Berg Balance Scale and the Static Balance Test, Pearson correlation coefficients were calculated. For inter-rater reliability, Bland Altman plots were drawn and the corresponding mean difference and limits of agreement were calculated. Results: The Static Balance Test took three to five minutes; the Berg Balance Scale 20-30 minutes. There was a high correlation between the scores on the Berg Balance Scale and the Static Balance Test (r=0.91). For the Berg Balance Scale, the mean difference between the two raters was 0.13 and the limits of agreement were small (-0.25; 0.51). For the Static Balance Test, the mean difference between the two raters was -0.02 and also the limits of agreement (-0.06; 0.02) were even smaller than for the Berg Balance Scale. Both scales showed excellent inter-rater reliability. Conclusion: The Static Balance Test was compared with the Berg Balance Scale and turned out to be equally valid, more reliable, and takes much less time. For the moment, the scale can be recommended for the use in acute stroke care, especially for the daily routine therapy."],["dc.identifier.doi","10.1177/0269215515578297"],["dc.identifier.isi","000371316400010"],["dc.identifier.pmid","25802425"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14327"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41296"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.relation.issn","1477-0873"],["dc.relation.issn","0269-2155"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","A comparison between the Static Balance Test and the Berg Balance Scale: validity, reliability, and comparative resource use"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","93"],["dc.bibliographiccitation.journal","BMC Medical Research Methodology"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Castell, Stefanie"],["dc.contributor.author","Morawietz, Lars"],["dc.contributor.author","Karch, Andre"],["dc.date.accessioned","2018-11-07T10:10:18Z"],["dc.date.available","2018-11-07T10:10:18Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: Reliability of measurements is a prerequisite of medical research. For nominal data, Fleiss' kappa (in the following labelled as Fleiss' K) and Krippendorff's alpha provide the highest flexibility of the available reliability measures with respect to number of raters and categories. Our aim was to investigate which measures and which confidence intervals provide the best statistical properties for the assessment of inter-rater reliability in different situations. Methods: We performed a large simulation study to investigate the precision of the estimates for Fleiss' K and Krippendorff's alpha and to determine the empirical coverage probability of the corresponding confidence intervals (asymptotic for Fleiss' K and bootstrap for both measures). Furthermore, we compared measures and confidence intervals in a real world case study. Results: Point estimates of Fleiss' K and Krippendorff's alpha did not differ from each other in all scenarios. In the case of missing data (completely at random), Krippendorff's alpha provided stable estimates, while the complete case analysis approach for Fleiss' K led to biased estimates. For shifted null hypotheses, the coverage probability of the asymptotic confidence interval for Fleiss' K was low, while the bootstrap confidence intervals for both measures provided a coverage probability close to the theoretical one. Conclusions: Fleiss' K and Krippendorff's alpha with bootstrap confidence intervals are equally suitable for the analysis of reliability of complete nominal data. The asymptotic confidence interval for Fleiss' K should not be used. In the case of missing data or data or higher than nominal order, Krippendorff's alpha is recommended. Together with this article, we provide an R-script for calculating Fleiss' K and Krippendorff's alpha and their corresponding bootstrap confidence intervals."],["dc.identifier.doi","10.1186/s12874-016-0200-9"],["dc.identifier.isi","000381100600001"],["dc.identifier.pmid","27495131"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13860"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39826"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1471-2288"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Measuring inter-rater reliability for nominal data - which coefficients and confidence intervals are appropriate?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","84"],["dc.bibliographiccitation.journal","BMC Neurology"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Koerner, Sonja"],["dc.contributor.author","Kollewe, Katja"],["dc.contributor.author","Abdulla, Susanne"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Dengler, Reinhard"],["dc.contributor.author","Petri, Susanne"],["dc.date.accessioned","2018-11-07T09:57:12Z"],["dc.date.available","2018-11-07T09:57:12Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Due to lack of any curative therapy for ALS, symptomatic treatment and maintenance of quality of life (QoL) is very important. We aimed to characterize the affected domains of QoL in ALS patients and to identify factors which are associated with reduced QoL and increased depression. Methods: 159 ALS patients answered standardized questionnaires (Beck Depression Inventory-II, SF-36 Health Survey questionnaire, revised ALS functional rating scale). Multiple regression analysis was used to identify correlations between clinical features of ALS patients and depression/QoL scores. In addition, QoL data from ALS patients were compared to age-matched reference values representing the German normal population. Results: QoL of ALS patients was reduced in nearly all SF-36-categories. Progression of physical impairment was positively correlated with depression but reduced QoL scores only in items directly related to physical function. However, QoL was considerably influenced by depression, independently from physical impairment. Regarding distinct patient characteristics one of the most interesting findings was that increasing age was correlated with significantly worse QoL results regarding social functioning. Conclusions: Depressive symptoms had a strong influence on QoL, hence their detection and treatment is of particular importance. Different domains of QoL are differently affected in subgroups of ALS patients. Being aware of these differences can be valuable for both ALS professional and family caregivers and physicians."],["dc.identifier.doi","10.1186/s12883-015-0340-2"],["dc.identifier.isi","000354920600001"],["dc.identifier.pmid","25982050"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12315"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37109"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1471-2377"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Interaction of physical function, quality of life and depression in Amyotrophic lateral sclerosis: characterization of a large patient cohort"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","11"],["dc.bibliographiccitation.artnumber","http://creativecommons.org/licenses/by/4.0/"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Diagnostic and Prognostic Research"],["dc.bibliographiccitation.volume","1"],["dc.contributor.author","Gopalakrishna, Gowri"],["dc.contributor.author","Langendam, Miranda"],["dc.contributor.author","Scholten, Rob"],["dc.contributor.author","Bossuyt, Patrick"],["dc.contributor.author","Leeflang, Mariska"],["dc.contributor.author","Noel-Storr, Anna"],["dc.contributor.author","Thomas, James"],["dc.contributor.author","Marshall, Iain"],["dc.contributor.author","Wallace, Byron"],["dc.contributor.author","Whiting, Penny"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Kramer, Katharina"],["dc.date.accessioned","2017-03-31T06:02:21Z"],["dc.date.accessioned","2021-10-27T13:20:57Z"],["dc.date.available","2017-03-31T06:02:21Z"],["dc.date.available","2021-10-27T13:20:57Z"],["dc.date.issued","2017"],["dc.date.updated","2017-03-31T06:02:21Z"],["dc.identifier.doi","10.1186/s41512-017-0011-4"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14398"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91985"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.iserratumof","/handle/2/58838"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","Goescholar"],["dc.rights.holder","The Author(s)"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Erratum to: Methods for evaluating medical tests and biomarkers"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","erratum_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]