Staiger, Jochen

[["dc.bibliographiccitation.firstpage","E1797"],["dc.bibliographiccitation.issue","19"],["dc.bibliographiccitation.journal","PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"],["dc.bibliographiccitation.lastpage","E1806"],["dc.bibliographiccitation.volume","110"],["dc.contributor.author","Harsan, Laura-Adela"],["dc.contributor.author","David, Csaba"],["dc.contributor.author","Reisert, Marco"],["dc.contributor.author","Schnell, Susanne"],["dc.contributor.author","Hennig, Juergen"],["dc.contributor.author","von Elverfeldt, Dominik"],["dc.contributor.author","Staiger, Jochen F."],["dc.date.accessioned","2018-11-07T09:24:45Z"],["dc.date.available","2018-11-07T09:24:45Z"],["dc.date.issued","2013"],["dc.description.abstract","A major challenge in neuroscience is to accurately decipher in vivo the entire brain circuitry (connectome) at a microscopic level. Currently, the only methodology providing a global noninvasive window into structural brain connectivity is diffusion tractography. The extent to which the reconstructed pathways reflect realistic neuronal networks depends, however, on data acquisition and postprocessing factors. Through a unique combination of approaches, we designed and evaluated herein a framework for reliable fiber tracking and mapping of the living mouse brain connectome. One important wiring scheme, connecting gray matter regions and passing fiber-crossing areas, was closely examined: the lemniscal thalamocortical (TC) pathway. We quantitatively validated the TC projections inferred from in vivo tractography with correlative histological axonal tracing in the same wild-type and reeler mutant mice. We demonstrated noninvasively that changes in patterning of the cortical sheet, such as highly disorganized cortical lamination in reeler, led to spectacular compensatory remodeling of the TC pathway."],["dc.identifier.doi","10.1073/pnas.1218330110"],["dc.identifier.isi","000319327700013"],["dc.identifier.pmid","23610438"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29900"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Natl Acad Sciences"],["dc.relation.issn","0027-8424"],["dc.title","Mapping remodeling of thalamocortical projections in the living reeler mouse brain by diffusion tractography"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of Investigative Dermatology"],["dc.bibliographiccitation.volume","132"],["dc.contributor.author","Ruzicka, Thomas"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Bodemer, Christine"],["dc.contributor.author","Traupe, Heiko"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Hoegger, Patrick J."],["dc.contributor.author","Lacour, J."],["dc.contributor.author","Blume-Peytavi, Ulrike"],["dc.contributor.author","Mazereeuw-Hautier, J."],["dc.contributor.author","Dupuy, P."],["dc.date.accessioned","2018-11-07T09:06:56Z"],["dc.date.available","2018-11-07T09:06:56Z"],["dc.date.issued","2012"],["dc.format.extent","S55"],["dc.identifier.isi","000307814000310"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25672"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Nature Publishing Group"],["dc.publisher.place","New york"],["dc.relation.conference","42nd Annual Meeting of the European-Society-for-Dermatological-Research (ESDR)"],["dc.relation.eventlocation","Venice, ITALY"],["dc.relation.issn","0022-202X"],["dc.title","Tazarotene cream in lamellar ichthyoses: a randomized, double-blind, vehicle-controlled and dose-finding clinical study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","607"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Nature Neuroscience"],["dc.bibliographiccitation.lastpage","612"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Gentet, Luc J."],["dc.contributor.author","Kremer, Yves"],["dc.contributor.author","Taniguchi, Hiroki"],["dc.contributor.author","Huang, Z. Josh"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Petersen, Carl C. H."],["dc.date.accessioned","2018-11-07T09:11:55Z"],["dc.date.available","2018-11-07T09:11:55Z"],["dc.date.issued","2012"],["dc.description.abstract","Neocortical GABAergic neurons have diverse molecular, structural and electrophysiological features, but the functional correlates of this diversity are largely unknown. We found unique membrane potential dynamics of somatostatin-expressing (SOM) neurons in layer 2/3 of the primary somatosensory barrel cortex of awake behaving mice. SOM neurons were spontaneously active during periods of quiet wakefulness. However, SOM neurons hyperpolarized and reduced action potential firing in response to both passive and active whisker sensing, in contrast with all other recorded types of nearby neurons, which were excited by sensory input. Optogenetic inhibition of SOM neurons increased burst firing in nearby excitatory neurons. We hypothesize that the spontaneous activity of SOM neurons during quiet wakefulness provides a tonic inhibition to the distal dendrites of excitatory pyramidal neurons. Conversely, the inhibition of SOM cells during active cortical processing likely enhances distal dendritic excitability, which may be important for top-down computations and sensorimotor integration."],["dc.identifier.doi","10.1038/nn.3051"],["dc.identifier.isi","000302114500021"],["dc.identifier.pmid","22366760"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26828"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Nature Publishing Group"],["dc.relation.issn","1097-6256"],["dc.title","Unique functional properties of somatostatin-expressing GABAergic neurons in mouse barrel cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S60"],["dc.bibliographiccitation.journal","Journal of Molecular Neuroscience"],["dc.bibliographiccitation.lastpage","S61"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Katz, Yonatan"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Lampl, I."],["dc.date.accessioned","2018-11-07T09:17:42Z"],["dc.date.available","2018-11-07T09:17:42Z"],["dc.date.issued","2013"],["dc.identifier.isi","000332833800151"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28231"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Humana Press Inc"],["dc.publisher.place","Totowa"],["dc.relation.conference","21st Annual Meeting of the Israel-Society-for-Neuroscience / 1st Binational Australian-Israeli Meeting on Neuroscience"],["dc.relation.eventlocation","Eilat, ISRAEL"],["dc.relation.issn","1559-1166"],["dc.relation.issn","0895-8696"],["dc.title","A special electrode holder for simultaneous intracellular patch recording and optical stimulation"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.firstpage","109"],["dc.bibliographiccitation.journal","iScience"],["dc.bibliographiccitation.lastpage","126"],["dc.bibliographiccitation.volume","4"],["dc.contributor.author","Narayanan, Ramanathan"],["dc.contributor.author","Pham, Linh"],["dc.contributor.author","Kerimoglu, Cemil"],["dc.contributor.author","Watanabe, Takashi"],["dc.contributor.author","Castro Hernandez, Ricardo"],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Ulmke, Pauline Antonie"],["dc.contributor.author","Kiszka, Kamila A."],["dc.contributor.author","Tonchev, Anton B."],["dc.contributor.author","Rosenbusch, Joachim"],["dc.contributor.author","Seong, Rho H."],["dc.contributor.author","Teichmann, Ulrike"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Fischer, Andre"],["dc.contributor.author","Bonn, Stefan"],["dc.contributor.author","Stoykova, Anastassia"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Tuoc, Tran"],["dc.date.accessioned","2020-12-10T14:24:42Z"],["dc.date.available","2020-12-10T14:24:42Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.isci.2018.05.014"],["dc.identifier.issn","2589-0042"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72326"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.firstpage","e2022701118"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Proceedings of the National Academy of Sciences of the United States of America"],["dc.bibliographiccitation.volume","118"],["dc.contributor.author","Yusifov, Rashad"],["dc.contributor.author","Tippmann, Anja"],["dc.contributor.author","Staiger, Jochen F."],["dc.contributor.author","Schlüter, Oliver M."],["dc.contributor.author","Löwel, Siegrid"],["dc.date.accessioned","2021-04-14T08:28:28Z"],["dc.date.available","2021-04-14T08:28:28Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1073/pnas.2022701118"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82616"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1091-6490"],["dc.relation.issn","0027-8424"],["dc.title","Spine dynamics of PSD-95-deficient neurons in the visual cortex link silent synapses to structural cortical plasticity"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","303"],["dc.bibliographiccitation.journal","Neuroscience"],["dc.bibliographiccitation.lastpage","316"],["dc.bibliographiccitation.volume","463"],["dc.contributor.author","Sokpor, Godwin"],["dc.contributor.author","Rosenbusch, Joachim"],["dc.contributor.author","Kunwar, Ajaya J."],["dc.contributor.author","Rickmann, Michael"],["dc.contributor.author","Tuoc, Tran"],["dc.contributor.author","Rizzoli, Silvio O."],["dc.contributor.author","Tarabykin, Victor"],["dc.contributor.author","von Mollard, Gabriele Fischer"],["dc.contributor.author","Krieglstein, Kerstin"],["dc.contributor.author","Staiger, Jochen F."],["dc.date.accessioned","2021-06-01T09:41:26Z"],["dc.date.available","2021-06-01T09:41:26Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1016/j.neuroscience.2021.03.021"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/84922"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","0306-4522"],["dc.title","Ablation of Vti1a/1b Triggers Neural Progenitor Pool Depletion and Cortical Layer 5 Malformation in Late-embryonic Mouse Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]