Malinova, Vesna

[["dc.bibliographiccitation.firstpage","1531"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Neurosurgical Review"],["dc.bibliographiccitation.lastpage","1537"],["dc.bibliographiccitation.volume","43"],["dc.contributor.author","Iliev, Bogdan"],["dc.contributor.author","Schlegel, Anna"],["dc.contributor.author","Mielke, Dorothee"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Malinova, Vesna"],["dc.date.accessioned","2020-12-10T14:11:13Z"],["dc.date.available","2020-12-10T14:11:13Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1007/s10143-019-01170-9"],["dc.identifier.eissn","1437-2320"],["dc.identifier.issn","0344-5607"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71004"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Intrahematomal catheter placement with connection to the ventricular system allows more effective thrombolysis of combined intracerebral and intraventricular hematomas"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","808"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Neurosurgery"],["dc.bibliographiccitation.lastpage","813"],["dc.bibliographiccitation.volume","133"],["dc.contributor.author","Malinova, Vesna"],["dc.contributor.author","Iliev, Bogdan"],["dc.contributor.author","Tsogkas, Ioannis"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.contributor.author","Mielke, Dorothee"],["dc.date.accessioned","2021-04-14T08:32:40Z"],["dc.date.available","2021-04-14T08:32:40Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.3171/2019.5.JNS19765"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83979"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1933-0693"],["dc.relation.issn","0022-3085"],["dc.title","Assessment of tissue permeability by early CT perfusion as a surrogate parameter for early brain injury after subarachnoid hemorrhage"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","165"],["dc.bibliographiccitation.issue","3-6"],["dc.bibliographiccitation.journal","Cerebrovascular Diseases"],["dc.bibliographiccitation.lastpage","170"],["dc.bibliographiccitation.volume","48"],["dc.contributor.author","Malinova, Vesna"],["dc.contributor.author","Iliev, Bogdan"],["dc.contributor.author","Mielke, Dorothee"],["dc.contributor.author","Rohde, Veit"],["dc.date.accessioned","2020-12-10T18:37:52Z"],["dc.date.available","2020-12-10T18:37:52Z"],["dc.date.issued","2019-11-13"],["dc.description.abstract","Objective: Intracerebral hemorrhage (ICH) is associated with high morbidity and mortality. Prognosis estimation would be helpful for the treatment decision making in ICH patients. The ICH-score was published in 2001 to estimate the 30-day mortality in conservatively treated patients with ICH. We evaluated the reproducibility of the ICH-score in ICH patients undergoing fibrinolytic therapy. Methods: We performed a retrospective analysis of patients with supratentorial ICH managed by fibrinolytic therapy and evaluated the 30-day mortality. The ICH-score was then applied to match the mortality in our patients with the mortality predicted by the ICH-score. The ICH-score is based on parameters available at admission: age, hematoma volume, intraventricular expansion, and clinical status according to the Glasgow Coma Scale. Results: A total of 233 patients were analyzed. The 30-day mortality rate was 30% (70/233). An age of ≥80 years was associated with a significantly higher mortality rate (OR 2.26, chi-square test p = 0.01). A hematoma volume of ≥30 mL led significantly more often to 30-day mortality (OR 3.72, chi-square test p = 0.01). The mortality was significantly higher in the patients with intraventricular hemorrhage (2.97, chi-square test p = 0.003). The ICH-score showed a significant correlation with mortality (chi-square test, p \\u0026lt; 0.0001). The following mortality rates were estimated using the ICH-score in our cohort: 1 = 0% (0/13), 2 = 0% (0/51), 3 = 1.3% (1/82), 4 = 43% (13/31), 5 = 100% (56/56). Conclusion: The ICH-score not only allows a reliable estimation of the 30-day mortality in patients with ICH treated conservatively but also treated by clot lysis. Compared to conservative treatment, the fibrinolytic therapy reduced the 30-day mortality in the patients with ICH-scores 1–4. Patients with ICH-score 5 do not have a benefit of fibrinolytic therapy and should no longer be considered to be candidates for fibrinolytic therapy."],["dc.identifier.doi","10.1159/000504246"],["dc.identifier.eissn","1421-9786"],["dc.identifier.issn","1015-9770"],["dc.identifier.pmid","31722333"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77125"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.publisher","S. Karger AG"],["dc.relation.eissn","1421-9786"],["dc.relation.issn","1015-9770"],["dc.rights","https://www.karger.com/Services/SiteLicenses"],["dc.title","Intracerebral Hemorrhage-Score Allows a Reliable Prediction of Mortality in Patients with Spontaneous Intracerebral Hemorrhage Managed by Fibrinolytic Therapy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Malinova, Vesna"],["dc.contributor.author","Psychogios, Marios-Nikos"],["dc.contributor.author","Tsogkas, Ioannis"],["dc.contributor.author","Koennecke, Birte"],["dc.contributor.author","Bleuel, Kim"],["dc.contributor.author","Iliev, Bogdan"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Mielke, Dorothee"],["dc.contributor.editor","Etminan, Nima"],["dc.date.accessioned","2018-10-08T09:08:05Z"],["dc.date.available","2018-10-08T09:08:05Z"],["dc.date.issued","2017"],["dc.description.abstract","Magnetic resonance (MR) imaging has been used for the detection of cerebral vasospasm (VSP) related infarction in experimental subarachnoid hemorrhage (eSAH) in rats. Conventional angiography is generally used to visualize VSP, which is an invasive technique with a possible increase in morbidity and mortality. In this study we evaluated the validity of MR-angiography (MRA) in detecting VSP and its feasibility to define VSP severity grades after eSAH in rats."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2017"],["dc.fs.pkfprnr","66455"],["dc.identifier.doi","10.1371/journal.pone.0171121"],["dc.identifier.fs","625670"],["dc.identifier.pmid","28182715"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14242"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15875"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.eissn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","MR-angiography allows defining severity grades of cerebral vasospasm in an experimental double blood injection subarachnoid hemorrhage model in rats"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]