Diering, Nina

[["dc.bibliographiccitation.journal","Onkologie"],["dc.bibliographiccitation.volume","33"],["dc.contributor.author","Diering, Nina"],["dc.contributor.author","Aung, T."],["dc.contributor.author","Chapuy, Björn"],["dc.contributor.author","Koch, R."],["dc.contributor.author","Becker, S."],["dc.contributor.author","Krause, D."],["dc.contributor.author","Truemper, Lorenz H."],["dc.contributor.author","Wulf, Gerald G."],["dc.date.accessioned","2018-11-07T08:38:49Z"],["dc.date.available","2018-11-07T08:38:49Z"],["dc.date.issued","2010"],["dc.format.extent","188"],["dc.identifier.isi","000282988401085"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18846"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","0378-584X"],["dc.title","Putative tumor stem cells of SP phenotype in aggressive B-cell lymphoma"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2189"],["dc.bibliographiccitation.issue","14"],["dc.bibliographiccitation.journal","Blood"],["dc.bibliographiccitation.lastpage","2198"],["dc.bibliographiccitation.volume","123"],["dc.contributor.author","Koch, Raphael"],["dc.contributor.author","Demant, Martin"],["dc.contributor.author","Aung, Thiha"],["dc.contributor.author","Diering, Nina"],["dc.contributor.author","Cicholas, Anna"],["dc.contributor.author","Chapuy, Björn"],["dc.contributor.author","Wenzel, Dirk"],["dc.contributor.author","Lahmann, Marlen"],["dc.contributor.author","Guentsch, Annemarie"],["dc.contributor.author","Kiecke, Christina"],["dc.contributor.author","Becker, Sabrina"],["dc.contributor.author","Hupfeld, Timo"],["dc.contributor.author","Venkataramani, Vivek"],["dc.contributor.author","Ziepert, Marita"],["dc.contributor.author","Opitz, Lennart"],["dc.contributor.author","Klapper, Wolfram"],["dc.contributor.author","Truemper, Lorenz H."],["dc.contributor.author","Wulf, Gerald G."],["dc.date.accessioned","2018-11-07T09:41:23Z"],["dc.date.available","2018-11-07T09:41:23Z"],["dc.date.issued","2014"],["dc.description.abstract","Tumors are composed of phenotypically heterogeneous cell populations. The non-genomic mechanisms underlying transitions and interactions between cell populations are largely unknown. Here, we show that diffuse large B-cell lymphomas possess a self-organized infrastructure comprising side population (SP) and non-SP cells, where transitions between clonogenic states are modulated by exosome-mediated Wnt signaling. DNA methylation modulated SP-non-SP transitions and was correlated with the reciprocal expressions of Wnt signaling pathway agonist Wnt3a in SP cells and the antagonist secreted frizzled-related protein 4 in non-SP cells. Lymphoma SP cells exhibited autonomous clonogenicity and exported Wnt3a via exosomes to neighboring cells, thus modulating population equilibrium in the tumor."],["dc.identifier.doi","10.1182/blood-2013-08-523886"],["dc.identifier.isi","000335889600015"],["dc.identifier.pmid","24563408"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33715"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1528-0020"],["dc.relation.issn","0006-4971"],["dc.title","Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Onkologie"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Koch, R."],["dc.contributor.author","Diering, Nina"],["dc.contributor.author","Lahmann, Marlen"],["dc.contributor.author","Demant, Martin"],["dc.contributor.author","Aung, T."],["dc.contributor.author","Chapuy, Björn"],["dc.contributor.author","Becker, S."],["dc.contributor.author","Sinzig, Ursula"],["dc.contributor.author","Truemper, Lorenz H."],["dc.contributor.author","Wulf, Gerald"],["dc.date.accessioned","2018-11-07T08:52:17Z"],["dc.date.available","2018-11-07T08:52:17Z"],["dc.date.issued","2011"],["dc.format.extent","190"],["dc.identifier.isi","000295160600502"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22131"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","0378-584X"],["dc.title","Homeostasis of lymphoma side population cells in aggressive B-cell lymphoma"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]