Andrés, Marta

[["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Pathogens and Global Health"],["dc.bibliographiccitation.volume","107"],["dc.contributor.author","Andres, Marta"],["dc.contributor.author","Karak, Somdatta"],["dc.contributor.author","Joo, Seol-hee"],["dc.contributor.author","Piepenbrock, David"],["dc.contributor.author","Göpfert, Martin C."],["dc.date.accessioned","2018-11-07T09:16:41Z"],["dc.date.available","2018-11-07T09:16:41Z"],["dc.date.issued","2013"],["dc.format.extent","406"],["dc.identifier.isi","000335056200021"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27988"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Maney Publishing"],["dc.publisher.place","Leeds"],["dc.relation.issn","2047-7732"],["dc.relation.issn","2047-7724"],["dc.title","DROSOPHILA MELANOGASTER AS A MODEL TO UNDERSTAND HEARING IN DISEASE VECTORS"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","363"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Developmental Cell"],["dc.bibliographiccitation.lastpage","364"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Andres, Marta"],["dc.contributor.author","Göpfert, Martin C."],["dc.date.accessioned","2018-11-07T09:36:26Z"],["dc.date.available","2018-11-07T09:36:26Z"],["dc.date.issued","2014"],["dc.description.abstract","Regulating the osmotic pressure of our body fluids relies on osmosensory neurons that depolarize when their volume decreases. Recently in Neuron, Prager-Khoutorsky et al. (2014) report that this depolarization arises from direct interactions between the transient receptor potential channel TRPV1 and microtubules, which seem to directly push open the channel."],["dc.identifier.doi","10.1016/j.devcel.2014.08.012"],["dc.identifier.isi","000341073500002"],["dc.identifier.pmid","25158850"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32620"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.relation.issn","1878-1551"],["dc.relation.issn","1534-5807"],["dc.title","Neuronal Osmotransduction: Push-Activating TRPV1 with Microtubules"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","67"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Neuron"],["dc.bibliographiccitation.lastpage","74"],["dc.bibliographiccitation.volume","98"],["dc.contributor.author","Zanini, Damiano"],["dc.contributor.author","Giraldo, Diego"],["dc.contributor.author","Warren, Ben"],["dc.contributor.author","Katana, Radoslaw"],["dc.contributor.author","Andrés, Marta"],["dc.contributor.author","Reddy, Suneel"],["dc.contributor.author","Pauls, Stephanie"],["dc.contributor.author","Schwedhelm-Domeyer, Nicola"],["dc.contributor.author","Geurten, Bart R. H."],["dc.contributor.author","Göpfert, Martin C."],["dc.date.accessioned","2019-07-12T09:33:09Z"],["dc.date.available","2019-07-12T09:33:09Z"],["dc.date.issued","2018"],["dc.description.abstract","Animals rely on mechanosensory feedback from proprioceptors to control locomotory body movements. Unexpectedly, we found that this movement control requires visual opsins. Disrupting the Drosophila opsins NINAE or Rh6 impaired larval locomotion and body contractions, independently of light and vision. Opsins were detected in chordotonal proprioceptors along the larval body, localizing to their ciliated dendrites. Loss of opsins impaired mechanically evoked proprioceptor spiking and cilium ultrastructure. Without NINAE or Rh6, NOMPC mechanotransduction channels leaked from proprioceptor cilia and ciliary Inactive (Iav) channels partly disappeared. Locomotion is shown to require opsins in proprioceptors, and the receptors are found to express the opsin gene Rh7, in addition to ninaE and Rh6. Besides implicating opsins in movement control, this documents roles of non-ciliary, rhabdomeric opsins in cilium organization, providing a model for a key transition in opsin evolution and suggesting that structural roles of rhabdomeric opsins preceded their use for light detection."],["dc.identifier.doi","10.1016/j.neuron.2018.02.028"],["dc.identifier.pmid","29551493"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/61475"],["dc.language.iso","en"],["dc.relation.eissn","1097-4199"],["dc.relation.issn","0896-6273"],["dc.title","Proprioceptive Opsin Functions in Drosophila Larval Locomotion"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","665"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Neuron"],["dc.bibliographiccitation.lastpage","671"],["dc.bibliographiccitation.volume","86"],["dc.contributor.author","Nesterov, Alexandre"],["dc.contributor.author","Spalthoff, Christian"],["dc.contributor.author","Kandasamy, Ramani A."],["dc.contributor.author","Katana, Radoslav"],["dc.contributor.author","Rankl, Nancy B."],["dc.contributor.author","Andres, Marta"],["dc.contributor.author","Jaehde, Philipp"],["dc.contributor.author","Dorsch, John A."],["dc.contributor.author","Stam, Lynn F."],["dc.contributor.author","Braun, Franz-Josef"],["dc.contributor.author","Warren, Ben"],["dc.contributor.author","Salgado, Vincent L."],["dc.contributor.author","Göpfert, Martin C."],["dc.date.accessioned","2018-11-07T09:57:21Z"],["dc.date.available","2018-11-07T09:57:21Z"],["dc.date.issued","2015"],["dc.description.abstract","Defining the molecular targets of insecticides is crucial for assessing their selectivity and potential impact on environment and health. Two commercial insecticides are now shown to target a transient receptor potential (TRP) ion channel complex that is unique to insect stretch receptor cells. Pymetrozine and pyrifluquinazon disturbed Drosophila coordination and hearing by acting on chordotonal stretch receptor neurons. This action required the two TRPs Nanchung (Nan) and Inactive (Iav), which co-occur exclusively within these cells. Nan and Iav together sufficed to confer cellular insecticide responses in vivo and in vitro, and the two insecticides were identified as specific agonists of Nan-Iav complexes that, by promoting cellular calcium influx, silence the stretch receptor cells. This establishes TRPs as insecticide targets and defines specific agonists of insect TRPs. It also shows that TRPs can render insecticides cell-type selective and puts forward TRP targets to reduce side effects on non-target species."],["dc.identifier.doi","10.1016/j.neuron.2015.04.001"],["dc.identifier.isi","000354069800009"],["dc.identifier.pmid","25950634"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37137"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.relation.issn","1097-4199"],["dc.relation.issn","0896-6273"],["dc.title","TRP Channels in Insect Stretch Receptors as Insecticide Targets"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2028"],["dc.bibliographiccitation.issue","15"],["dc.bibliographiccitation.journal","Current Biology"],["dc.bibliographiccitation.lastpage","2036"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Andres, Marta"],["dc.contributor.author","Seifert, Marvin"],["dc.contributor.author","Spalthoff, Christian"],["dc.contributor.author","Warren, Ben"],["dc.contributor.author","Weiss, Lukas"],["dc.contributor.author","Giraldo, Diego"],["dc.contributor.author","Winkler, Margret"],["dc.contributor.author","Pauls, Stephanie"],["dc.contributor.author","Göpfert, Martin C."],["dc.date.accessioned","2018-11-07T10:10:16Z"],["dc.date.available","2018-11-07T10:10:16Z"],["dc.date.issued","2016"],["dc.description.abstract","The performance of vertebrate ears is controlled by auditory efferents that originate in the brain and innervate the ear, synapsing onto hair cell somata and auditory afferent fibers [1-3]. Efferent activity can provide protection from noise and facilitate the detection and discrimination of sound by modulating mechanical amplification by hair cells and transmitter release as well as auditory afferent action potential firing [1-3]. Insect auditory organs are thought to lack efferent control [4-7], but when we inspected mosquito ears, we obtained evidence for its existence. Antibodies against synaptic proteins recognized rows of bouton-like puncta running along the dendrites and axons of mosquito auditory sensory neurons. Electron microscopy identified synaptic and non-synaptic sites of vesicle release, and some of the innervating fibers co-labeled with somata in the CNS. Octopamine, GABA, and serotonin were identified as efferent neurotransmitters or neuromodulators that affect auditory frequency tuning, mechanical amplification, and sound-evoked potentials. Mosquito brains thus modulate mosquito ears, extending the use of auditory efferent systems from vertebrates to invertebrates and adding new levels of complexity to mosquito sound detection and communication."],["dc.identifier.doi","10.1016/j.cub.2016.05.077"],["dc.identifier.isi","000381241100026"],["dc.identifier.pmid","27476597"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39818"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.relation.issn","1879-0445"],["dc.relation.issn","0960-9822"],["dc.title","Auditory Efferent System Modulates Mosquito Hearing"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","255"],["dc.bibliographiccitation.journal","Malaria Journal"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Andres, Marta"],["dc.contributor.author","Lorenz, Lena M."],["dc.contributor.author","Mbeleya, Edgar"],["dc.contributor.author","Moore, Sarah J."],["dc.date.accessioned","2018-11-07T09:55:42Z"],["dc.date.available","2018-11-07T09:55:42Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Efforts to control malaria vectors have primarily focused on scaling-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying. Although highly efficient against indoor-biting and indoor-resting vectors, these interventions have lower impact on outdoor-biting mosquitoes. Innovative vector control tools are required to prevent outdoor human-mosquito contacts. In this work, the potential of spatial repellents, delivered in an active system that requires minimal user compliance, to provide personal protection against exophagic mosquitoes active in the early evening was explored. Methods: A device previously used as an odour-baited lure and kill apparatus, the mosquito landing box (MLB), was modified to dispense the volatile synthetic pyrethroid, transfluthrin, as a spatial repellent. The MLB has an active odour-dispensing mechanism that uses a solar-powered fan and switches on at dusk to provide long duration dispensing of volatile compounds without the need for the user to remember to employ it. Two MLBs were located 5 m from a human volunteer to investigate the repellent effects of a transfluthrin 'bubble' created between the MLBs. Transfluthrin was emanated from polyester strips, hanging inside the MLB odour-dispensing unit. A fully randomized cross-over design was performed in a large, semi-field, screened cage to assess the effect of the repellent against laboratory-reared Anopheles arabiensis mosquitoes under ambient outdoor conditions. The knock-down capacity of the transfluthrin-treated strips was also evaluated at different time points up to 3 weeks after being impregnated to measure duration of efficacy. Results: The protective transfluthrin bubble provided 68.9% protection against An. arabiensis bites under these simulated outdoor conditions. Volatile transfluthrin caused low mortality among mosquitoes in the semi-field system. Transfluthrin-treated strips continued to knock down mosquitoes in laboratory tests, 3 weeks after impregnation, although this effect diminished with time. Conclusion: Modified MLBs can be used as efficient and long-lasting dispensers of volatile spatial repellents such as transfluthrin, thereby providing high levels of protection against outdoor-biting mosquitoes in the peri-domestic space. They have a potential role in combatting outdoor malaria transmission without interfering with effective indoor interventions such as LLINs."],["dc.identifier.doi","10.1186/s12936-015-0762-8"],["dc.identifier.isi","000356657300002"],["dc.identifier.pmid","26104719"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12514"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36809"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1475-2875"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Modified mosquito landing boxes dispensing transfluthrin provide effective protection against Anopheles arabiensis mosquitoes under simulated outdoor conditions in a semi-field system"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1091"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Genetics"],["dc.bibliographiccitation.lastpage","1102"],["dc.bibliographiccitation.volume","196"],["dc.contributor.author","Andres, Marta"],["dc.contributor.author","Turiegano, Enrique"],["dc.contributor.author","Göpfert, Martin C."],["dc.contributor.author","Canal, Inmaculada"],["dc.contributor.author","Torroja, Laura"],["dc.date.accessioned","2018-11-07T09:41:38Z"],["dc.date.available","2018-11-07T09:41:38Z"],["dc.date.issued","2014"],["dc.description.abstract","Sensory cilia are often encapsulated by an extracellular matrix (ECM). In Caenorhabditis elegans, Drosophila melanogaster, and vertebrates, this ECM is thought to be directly involved in ciliary mechanosensing by coupling external forces to the ciliary membrane. Drosophila mechano- and chemosensory cilia are both associated with an ECM, indicating that the ECM may have additional roles that go beyond mechanosensory cilium function. Here, we identify Artichoke (ATK), an evolutionarily conserved leucine-rich repeat ECM protein that is required for normal morphogenesis and function of ciliated sensilla in Drosophila. atk is transiently expressed in accessory cells in all ciliated sensory organs during their late embryonic development. Antibody stainings show ATK protein in the ECM that surrounds sensory cilia. Loss of ATK protein in atk null mutants leads to cilium deformation and disorientation in chordotonal organs, apparently without uncoupling the cilia from the ECM, and consequently to locomotion defects. Moreover, impaired chemotaxis in atk mutant larvae suggests that, based on ATK protein localization, the ECM is also crucial for the correct assembly of chemosensory receptors. In addition to defining a novel ECM component, our findings show the importance of ECM integrity for the proper morphogenesis of ciliated organs in different sensory modalities."],["dc.identifier.doi","10.1534/genetics.113.156323"],["dc.identifier.isi","000334179300016"],["dc.identifier.pmid","24496014"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33778"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Genetics Soc Am"],["dc.relation.issn","1943-2631"],["dc.relation.issn","0016-6731"],["dc.title","The Extracellular Matrix Protein Artichoke Is Required for Integrity of Ciliated Mechanosensory and Chemosensory Organs in Drosophila Embryos"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]