Kramm, Christof M.

[["dc.bibliographiccitation.journal","Brain Pathology"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Gielen, Gerrit H."],["dc.contributor.author","zur Muehlen, Anja"],["dc.contributor.author","Wolff, J."],["dc.contributor.author","Kwiecien, Robert"],["dc.contributor.author","Kramm, C."],["dc.date.accessioned","2018-11-07T09:35:54Z"],["dc.date.available","2018-11-07T09:35:54Z"],["dc.date.issued","2014"],["dc.format.extent","74"],["dc.identifier.isi","000342165800267"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32494"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","18th International Congress of Neuropathology"],["dc.relation.eventlocation","Rio de Janeiro, BRAZIL"],["dc.relation.issn","1750-3639"],["dc.relation.issn","1015-6305"],["dc.title","Histopathological grading according to the WHO classification of CNS tumors and H3.3K27 mutational status represent independent prognostic markers in pediatric high grade gliomas"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","27"],["dc.bibliographiccitation.journal","European Journal of Cancer"],["dc.bibliographiccitation.lastpage","35"],["dc.bibliographiccitation.volume","114"],["dc.contributor.author","Pfaff, Elke"],["dc.contributor.author","El Damaty, Ahmed"],["dc.contributor.author","Balasubramanian, Gnana Prakash"],["dc.contributor.author","Blattner-Johnson, Mirjam"],["dc.contributor.author","Worst, Barbara C."],["dc.contributor.author","Stark, Sebastian"],["dc.contributor.author","Witt, Hendrik"],["dc.contributor.author","Pajtler, Kristian W."],["dc.contributor.author","van Tilburg, Cornelis M."],["dc.contributor.author","Witt, Ruth"],["dc.contributor.author","Milde, Till"],["dc.contributor.author","Jakobs, Martin"],["dc.contributor.author","Fiesel, Petra"],["dc.contributor.author","Frühwald, Michael C."],["dc.contributor.author","Hernáiz Driever, Pablo"],["dc.contributor.author","Thomale, Ulrich W."],["dc.contributor.author","Schuhmann, Martin U."],["dc.contributor.author","Metzler, Markus"],["dc.contributor.author","Bochennek, Konrad"],["dc.contributor.author","Simon, Thorsten"],["dc.contributor.author","Dürken, Matthias"],["dc.contributor.author","Karremann, Michael"],["dc.contributor.author","Knirsch, Stephanie"],["dc.contributor.author","Ebinger, Martin"],["dc.contributor.author","von Bueren, André O."],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Herold-Mende, Christel"],["dc.contributor.author","Reuss, David E."],["dc.contributor.author","Kiening, Karl"],["dc.contributor.author","Lichter, Peter"],["dc.contributor.author","Eggert, Angelika"],["dc.contributor.author","Kramm, Christof M."],["dc.contributor.author","Pfister, Stefan M."],["dc.contributor.author","Jones, David T.W."],["dc.contributor.author","Bächli, Heidi"],["dc.contributor.author","Witt, Olaf"],["dc.date.accessioned","2020-12-10T14:23:39Z"],["dc.date.available","2020-12-10T14:23:39Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.ejca.2019.03.019"],["dc.identifier.issn","0959-8049"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72003"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","844"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","British Journal of Cancer"],["dc.bibliographiccitation.lastpage","851"],["dc.bibliographiccitation.volume","109"],["dc.contributor.author","Karremann, Michael"],["dc.contributor.author","Rausche, U."],["dc.contributor.author","Roth, D."],["dc.contributor.author","Kuehn, A."],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Gielen, Gerrit H."],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Kortmann, R-D"],["dc.contributor.author","Straeter, R."],["dc.contributor.author","Gnekow, Astrid"],["dc.contributor.author","Wolff, J. E. A."],["dc.contributor.author","Kramm, Christof M."],["dc.date.accessioned","2018-11-07T09:21:12Z"],["dc.date.available","2018-11-07T09:21:12Z"],["dc.date.issued","2013"],["dc.description.abstract","Background: High-grade glioma (HGG) of the cerebellum accounts for only 5% of paediatric HGG. Since little is known about these tumours, the present study aimed at their further characterisation. Methods: Twenty-nine paediatric patients with centrally reviewed cerebellar HGG were identified from the HIT-GBM/HIT-HGG database. Clinical and epidemiological data were compared with those of 180 paediatric patients with cortical HGG. Results: Patients with cerebellar tumours were younger (median age of 7.6 vs 11.7 years, P = 0.028), but both groups did not differ significantly with regard to gender, tumour predisposing syndromes, secondary HGG, primary metastasis, tumour grading, extent of tumour resection, chemotherapy regimen, or radiotherapy. Except for an increased incidence of anaplastic pilocytic astrocytoma (APA) in the cerebellar subset (20.7% vs 3.3%; P<0.001), histological entities were similarly distributed in both groups. As expected, tumour grading had a prognostic relevance on survival. Compared with cortical HGG, overall survival in the cerebellar location was significantly worse (median overall survival: 0.92+/-0.02 vs 2.03+/-0.32 years; P = 0.0064), and tumour location in the cerebellum had an independent poor prognostic significance as shown by Cox-regression analysis (P = 0.019). Conclusion: High-grade glioma represents a group of tumours with an obviously site-specific heterogeneity associated with a worse survival in cerebellar location."],["dc.description.sponsorship","Deutsche Kinderkrebsstiftung, Bonn, Germany"],["dc.identifier.doi","10.1038/bjc.2013.404"],["dc.identifier.isi","000323417100003"],["dc.identifier.pmid","23868007"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29059"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0007-0920"],["dc.title","Cerebellar location may predict an unfavourable prognosis in paediatric high-grade glioma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Friedrich, Carsten"],["dc.contributor.author","Kuehn, Alexander"],["dc.contributor.author","Zimmermann, Martin"],["dc.contributor.author","Hoffmann, Marion"],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","Nowak, Johannes"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Schrappe, Martin"],["dc.contributor.author","Escherich, Gabriele"],["dc.contributor.author","Burkhardt, Birgit"],["dc.contributor.author","Kortmann, Rolf-Dieter"],["dc.contributor.author","von Bueren, Andre Oscar"],["dc.contributor.author","Kramm, Christof M."],["dc.date.accessioned","2018-11-07T10:13:06Z"],["dc.date.available","2018-11-07T10:13:06Z"],["dc.date.issued","2016"],["dc.format.extent","55"],["dc.identifier.isi","000379749000210"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40369"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.publisher.place","Cary"],["dc.relation.conference","17th International Symposium on Pediatric Neuro-Oncology (ISPNO)"],["dc.relation.eventlocation","Liverpool, ENGLAND"],["dc.relation.issn","1523-5866"],["dc.relation.issn","1522-8517"],["dc.title","HIGH-GRADE GLIOMA ARISING IN SURVIVORS OF PEDIATRIC ACUTE LYMPHOBLASTIC MALIGNANCIES: A COOPERATIVE ANALYSIS OF THE GERMAN HIT-HGG/-GBM AND ALL-BFM/COALL STUDIES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","669"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Pediatric Research"],["dc.bibliographiccitation.lastpage","676"],["dc.bibliographiccitation.volume","87"],["dc.contributor.author","Pötschke, Rebecca"],["dc.contributor.author","Gielen, Gerrit"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Kramm, Christof"],["dc.contributor.author","Klusmann, Jan-Henning"],["dc.contributor.author","Hüttelmaier, Stefan"],["dc.contributor.author","Kühnöl, Caspar D."],["dc.date.accessioned","2021-04-14T08:27:12Z"],["dc.date.available","2021-04-14T08:27:12Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1038/s41390-019-0628-9"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82202"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1530-0447"],["dc.relation.issn","0031-3998"],["dc.title","Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Pediatric Blood & Cancer"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Classen, Carl Friedrich"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Kramm, C."],["dc.date.accessioned","2018-11-07T09:49:56Z"],["dc.date.available","2018-11-07T09:49:56Z"],["dc.date.issued","2015"],["dc.format.extent","S214"],["dc.identifier.isi","000361247200270"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35604"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1545-5017"],["dc.relation.issn","1545-5009"],["dc.title","CLINICAL AND MOLECULAR RESULTS OF THE GERMAN PHASE II STUDY HIT-HGG-CILMETRO: CILENGITIDE AND METRONOMIC TEMOZOLOMIDE FOR RELAPSED/REFRACTORY HIGH GRADE GLIOMAS/DIPG IN CHILDREN AND ADOLESCENTS"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","78"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Acta Neuropathologica Communications"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Andreiuolo, Felipe"],["dc.contributor.author","Lisner, Tomo"],["dc.contributor.author","Zlocha, Jozef"],["dc.contributor.author","Kramm, Christof"],["dc.contributor.author","Koch, Arend"],["dc.contributor.author","Bison, Brigitte"],["dc.contributor.author","Gareton, Albane"],["dc.contributor.author","Zanello, Marc"],["dc.contributor.author","Waha, Andreas"],["dc.contributor.author","Varlet, Pascale"],["dc.contributor.author","Pietsch, Torsten"],["dc.date.accessioned","2019-07-09T11:51:43Z"],["dc.date.available","2019-07-09T11:51:43Z"],["dc.date.issued","2019"],["dc.description.abstract","The recently described malignant neuro-epithelial tumors with histone H3F3A point mutations at G34 (NET-H3-G34) occur most often in cerebral hemispheres of teenagers and young adults, and have a generally adverse prognosis. These tumors have been histologically classified as glioblastoma or primitive neuroectodermal tumor (PNET) in the past, and have not been defined as a separate entity in the revised WHO classification of tumors of the CNS 2016. Here, we report two cases of NET-H3-G34 with glial and dysplastic ganglion cell components affecting teenagers. Patients were treated with surgery and radiochemotherapy with temozolomide. One patient underwent partial resection and deceased 21 months after diagnosis, while the other patient is alive without evidence of disease 15 months after total resection. So far, a dysplastic ganglion cell component has not been described in NET-H-G34, and its presence raises a possible relation to (anaplastic) gangliogliomas. Genome-wide copy number analysis did not provide unequivocal evidence that these tumors represent anaplastic variants of gangliogliomas, as opposed to NET-H3-G34. Our observations expand the morphologic spectrum of NET-H3-G34. Further cases of NET-H3-G34 with dysplastic ganglion cells should be clinically followed to find differences or similarities in their biological behavior, as compared to NET-H3-G34 and anaplastic gangliogliomas."],["dc.identifier.doi","10.1186/s40478-019-0731-5"],["dc.identifier.pmid","31109382"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16172"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59991"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.title","H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","215"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Strahlentherapie und Onkologie"],["dc.bibliographiccitation.lastpage","224"],["dc.bibliographiccitation.volume","194"],["dc.contributor.author","Seidel, Clemens"],["dc.contributor.author","von Bueren, André O."],["dc.contributor.author","Bojko, Sabrina"],["dc.contributor.author","Hoffmann, Marion"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Gielen, Gerrit H."],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Bison, Brigitte"],["dc.contributor.author","Kortmann, Rolf‑D."],["dc.contributor.author","Kramm, Christof M."],["dc.date.accessioned","2020-12-10T14:08:04Z"],["dc.date.available","2020-12-10T14:08:04Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00066-017-1218-6"],["dc.identifier.eissn","1439-099X"],["dc.identifier.issn","0179-7158"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70366"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Konkomitante Radiochemotherapie mit Temozolomid vs. konkomitante Cisplatin-basierte Radiochemotherapie"],["dc.title.alternative","Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen. Acute toxicity in pediatric high-grade glioma patients"],["dc.title.subtitle","Akuttoxizität bei Kindern mit hochmalignen Gliomen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","55"],["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.lastpage","56"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Gielen, Gerrit H."],["dc.contributor.author","Muehlen, Anja Zur"],["dc.contributor.author","Kwiecien, Robert"],["dc.contributor.author","Wolff, Johannes"],["dc.contributor.author","Kramm, Christof"],["dc.date.accessioned","2018-11-07T09:39:21Z"],["dc.date.available","2018-11-07T09:39:21Z"],["dc.date.issued","2014"],["dc.identifier.isi","000337924200210"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33258"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.publisher.place","Cary"],["dc.relation.conference","16th International Symposium on Pediatric Neuro-Oncology (ISPNO)"],["dc.relation.eventlocation","Singapore, SINGAPORE"],["dc.relation.issn","1523-5866"],["dc.relation.issn","1522-8517"],["dc.title","HISTOPATHOLOGICAL GRADING ACCORDING TO THE WHO CLASSIFICATION OF CNS TUMORS AND H3.3K27 MUTATIONAL STATUS REPRESENT INDEPENDENT PROGNOSTIC MARKERS IN PEDIATRIC HIGH GRADE GLIOMAS"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","65"],["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.lastpage","66"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Hoffman, Lindsey M."],["dc.contributor.author","van Zanten, Sophie Veldhuijzen"],["dc.contributor.author","Colditz, Niclas"],["dc.contributor.author","Baugh, Joshua"],["dc.contributor.author","Chaney, Brooklyn"],["dc.contributor.author","Lane, Adam"],["dc.contributor.author","Fuller, Christine"],["dc.contributor.author","Miles, Lili"],["dc.contributor.author","Hawkins, Cynthia"],["dc.contributor.author","Bartels, Ute"],["dc.contributor.author","Bouffet, Eric"],["dc.contributor.author","Goldman, Stewart"],["dc.contributor.author","Leary, Sarah"],["dc.contributor.author","Foreman, Nicholas K."],["dc.contributor.author","Packer, Roger"],["dc.contributor.author","Warren, Katherine E."],["dc.contributor.author","Broniscer, Alberto"],["dc.contributor.author","Kieran, Mark W."],["dc.contributor.author","Minturn, Jane"],["dc.contributor.author","Comito, Melanie"],["dc.contributor.author","Broxon, Emmett"],["dc.contributor.author","Shih, Chie-Schin"],["dc.contributor.author","Khatua, Soumen"],["dc.contributor.author","Chintagumpala, Murali"],["dc.contributor.author","Carret, Anne-Sophie"],["dc.contributor.author","Hassall, Timothy"],["dc.contributor.author","Ziegler, David S."],["dc.contributor.author","Gottardo, Nick"],["dc.contributor.author","Dholaria, Hetal"],["dc.contributor.author","Lerme, Brianna"],["dc.contributor.author","Kirkendall, Jenavieve"],["dc.contributor.author","Doughman, Renee"],["dc.contributor.author","Hoffmann, Marion"],["dc.contributor.author","Wollman, Matthew"],["dc.contributor.author","O'Keefe, Rachel"],["dc.contributor.author","Benesch, Martin"],["dc.contributor.author","Gerber, Nicolas U."],["dc.contributor.author","Bailey, Simon"],["dc.contributor.author","Solanki, Guirish"],["dc.contributor.author","Massimino, Maura"],["dc.contributor.author","Biassoni, Veronica"],["dc.contributor.author","Cvrlje, Filip Jadrijevic"],["dc.contributor.author","Hulleman, Esther"],["dc.contributor.author","Drissi, Rachid"],["dc.contributor.author","Nazarian, Javad"],["dc.contributor.author","Jabado, Nada"],["dc.contributor.author","von Bueren, Andre Oscar"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Gielen, Gerrit H."],["dc.contributor.author","Sturm, Dominik"],["dc.contributor.author","Jones, David T. W."],["dc.contributor.author","Pfister, Stefan M."],["dc.contributor.author","Jones, Chris"],["dc.contributor.author","Hargrave, Darren"],["dc.contributor.author","Sanchez, Esther"],["dc.contributor.author","Bison, Brigitte"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Leach, James"],["dc.contributor.author","Jones, Blaise"],["dc.contributor.author","van Vuurden, Dannis G."],["dc.contributor.author","Kramm, Christof M."],["dc.contributor.author","Fouladi, Maryam"],["dc.date.accessioned","2018-11-07T10:13:07Z"],["dc.date.available","2018-11-07T10:13:07Z"],["dc.date.issued","2016"],["dc.identifier.isi","000379749000250"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40370"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.publisher.place","Cary"],["dc.relation.conference","17th International Symposium on Pediatric Neuro-Oncology (ISPNO)"],["dc.relation.eventlocation","Liverpool, ENGLAND"],["dc.relation.issn","1523-5866"],["dc.relation.issn","1522-8517"],["dc.title","CLINICAL, RADIOLOGICAL, AND HISTO-GENETIC CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA: A COLLABORATIVE REPORT FROM THE INTERNATIONAL AND SIOP-E DIPG REGISTRIES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]