Kramm, Christof M.

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Cancer Immunology Research"],["dc.bibliographiccitation.volume","4"],["dc.contributor.author","Eyrich, Matthias"],["dc.contributor.author","Krauss, Juergen"],["dc.contributor.author","Loehr, Mario"],["dc.contributor.author","Technau, Antje"],["dc.contributor.author","Rachor, Johannes"],["dc.contributor.author","Monoranu, Camelia"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Woelfl, Matthias"],["dc.contributor.author","Kramm, Christof"],["dc.contributor.author","Schlegel, Paul Gerhardt"],["dc.date.accessioned","2018-11-07T10:20:25Z"],["dc.date.available","2018-11-07T10:20:25Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1158/2326-6074.CRICIMTEATIAACR15-A045"],["dc.identifier.isi","000375484400036"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41886"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Cancer Research"],["dc.publisher.place","Philadelphia"],["dc.relation.issn","2326-6074"],["dc.relation.issn","2326-6066"],["dc.title","Dendritic cell vaccination with partial Treg depletion in relapsed glioblastoma - results from the pilot phase of the HIT-HGG Rez Immunvac study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","844"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","British Journal of Cancer"],["dc.bibliographiccitation.lastpage","851"],["dc.bibliographiccitation.volume","109"],["dc.contributor.author","Karremann, Michael"],["dc.contributor.author","Rausche, U."],["dc.contributor.author","Roth, D."],["dc.contributor.author","Kuehn, A."],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Gielen, Gerrit H."],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Kortmann, R-D"],["dc.contributor.author","Straeter, R."],["dc.contributor.author","Gnekow, Astrid"],["dc.contributor.author","Wolff, J. E. A."],["dc.contributor.author","Kramm, Christof M."],["dc.date.accessioned","2018-11-07T09:21:12Z"],["dc.date.available","2018-11-07T09:21:12Z"],["dc.date.issued","2013"],["dc.description.abstract","Background: High-grade glioma (HGG) of the cerebellum accounts for only 5% of paediatric HGG. Since little is known about these tumours, the present study aimed at their further characterisation. Methods: Twenty-nine paediatric patients with centrally reviewed cerebellar HGG were identified from the HIT-GBM/HIT-HGG database. Clinical and epidemiological data were compared with those of 180 paediatric patients with cortical HGG. Results: Patients with cerebellar tumours were younger (median age of 7.6 vs 11.7 years, P = 0.028), but both groups did not differ significantly with regard to gender, tumour predisposing syndromes, secondary HGG, primary metastasis, tumour grading, extent of tumour resection, chemotherapy regimen, or radiotherapy. Except for an increased incidence of anaplastic pilocytic astrocytoma (APA) in the cerebellar subset (20.7% vs 3.3%; P<0.001), histological entities were similarly distributed in both groups. As expected, tumour grading had a prognostic relevance on survival. Compared with cortical HGG, overall survival in the cerebellar location was significantly worse (median overall survival: 0.92+/-0.02 vs 2.03+/-0.32 years; P = 0.0064), and tumour location in the cerebellum had an independent poor prognostic significance as shown by Cox-regression analysis (P = 0.019). Conclusion: High-grade glioma represents a group of tumours with an obviously site-specific heterogeneity associated with a worse survival in cerebellar location."],["dc.description.sponsorship","Deutsche Kinderkrebsstiftung, Bonn, Germany"],["dc.identifier.doi","10.1038/bjc.2013.404"],["dc.identifier.isi","000323417100003"],["dc.identifier.pmid","23868007"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29059"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0007-0920"],["dc.title","Cerebellar location may predict an unfavourable prognosis in paediatric high-grade glioma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","693"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Strahlentherapie und Onkologie"],["dc.bibliographiccitation.lastpage","696"],["dc.bibliographiccitation.volume","189"],["dc.contributor.author","Mueller, K."],["dc.contributor.author","Schlamann, Annika"],["dc.contributor.author","Seidel, C."],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Christiansen, H."],["dc.contributor.author","Vordermark, Dirk"],["dc.contributor.author","Kortmann, R.-D."],["dc.contributor.author","Kramm, Christof M."],["dc.contributor.author","von Bueren, A. O."],["dc.date.accessioned","2018-11-07T09:22:03Z"],["dc.date.available","2018-11-07T09:22:03Z"],["dc.date.issued","2013"],["dc.description.abstract","Primary metastatic diffuse intrinsic pontine glioma (DIPG) is relatively rare and associated with a dismal prognosis. Combining craniospinal irradiation (CSI) with concurrent temozolomide and nimotuzumab therapy may slightly improve tumor control and overall survival. However, little is known about the feasibility and toxicity of this treatment approach. Here, we describe the case of an 8-year-old girl with primary metastatic DIPG who received craniospinal radiotherapy, a local boost, and concurrent temozolomide and nimotuzumab treatment based on an individual therapy recommendation. Radiotherapy could be completed without any interruption. However, concurrent temozolomide had to be disrupted several times due to considerable acute myelotoxicity (grade III-IV).Maintenance immunochemotherapy could be started with a delay of 5 days and was performed according to treatment schedule. The disease could be stabilized for a few months. A routine MRI scan finally depicted disease progression 5.7 months after the start of irradiation. The patient died 1.9 months later."],["dc.identifier.doi","10.1007/s00066-013-0370-x"],["dc.identifier.isi","000322388100012"],["dc.identifier.pmid","23754473"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29251"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Urban & Vogel"],["dc.relation.issn","0179-7158"],["dc.title","Craniospinal irradiation with concurrent temozolomide and nimotuzumab in a child with primary metastatic diffuse intrinsic pontine glioma A compassionate use treatment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Friedrich, Carsten"],["dc.contributor.author","Kuehn, Alexander"],["dc.contributor.author","Zimmermann, Martin"],["dc.contributor.author","Hoffmann, Marion"],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","Nowak, Johannes"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Schrappe, Martin"],["dc.contributor.author","Escherich, Gabriele"],["dc.contributor.author","Burkhardt, Birgit"],["dc.contributor.author","Kortmann, Rolf-Dieter"],["dc.contributor.author","von Bueren, Andre Oscar"],["dc.contributor.author","Kramm, Christof M."],["dc.date.accessioned","2018-11-07T10:13:06Z"],["dc.date.available","2018-11-07T10:13:06Z"],["dc.date.issued","2016"],["dc.format.extent","55"],["dc.identifier.isi","000379749000210"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40369"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.publisher.place","Cary"],["dc.relation.conference","17th International Symposium on Pediatric Neuro-Oncology (ISPNO)"],["dc.relation.eventlocation","Liverpool, ENGLAND"],["dc.relation.issn","1523-5866"],["dc.relation.issn","1522-8517"],["dc.title","HIGH-GRADE GLIOMA ARISING IN SURVIVORS OF PEDIATRIC ACUTE LYMPHOBLASTIC MALIGNANCIES: A COOPERATIVE ANALYSIS OF THE GERMAN HIT-HGG/-GBM AND ALL-BFM/COALL STUDIES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","215"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Strahlentherapie und Onkologie"],["dc.bibliographiccitation.lastpage","224"],["dc.bibliographiccitation.volume","194"],["dc.contributor.author","Seidel, Clemens"],["dc.contributor.author","von Bueren, André O."],["dc.contributor.author","Bojko, Sabrina"],["dc.contributor.author","Hoffmann, Marion"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Gielen, Gerrit H."],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Bison, Brigitte"],["dc.contributor.author","Kortmann, Rolf‑D."],["dc.contributor.author","Kramm, Christof M."],["dc.date.accessioned","2020-12-10T14:08:04Z"],["dc.date.available","2020-12-10T14:08:04Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00066-017-1218-6"],["dc.identifier.eissn","1439-099X"],["dc.identifier.issn","0179-7158"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70366"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Konkomitante Radiochemotherapie mit Temozolomid vs. konkomitante Cisplatin-basierte Radiochemotherapie"],["dc.title.alternative","Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen. Acute toxicity in pediatric high-grade glioma patients"],["dc.title.subtitle","Akuttoxizität bei Kindern mit hochmalignen Gliomen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","65"],["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.lastpage","66"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Hoffman, Lindsey M."],["dc.contributor.author","van Zanten, Sophie Veldhuijzen"],["dc.contributor.author","Colditz, Niclas"],["dc.contributor.author","Baugh, Joshua"],["dc.contributor.author","Chaney, Brooklyn"],["dc.contributor.author","Lane, Adam"],["dc.contributor.author","Fuller, Christine"],["dc.contributor.author","Miles, Lili"],["dc.contributor.author","Hawkins, Cynthia"],["dc.contributor.author","Bartels, Ute"],["dc.contributor.author","Bouffet, Eric"],["dc.contributor.author","Goldman, Stewart"],["dc.contributor.author","Leary, Sarah"],["dc.contributor.author","Foreman, Nicholas K."],["dc.contributor.author","Packer, Roger"],["dc.contributor.author","Warren, Katherine E."],["dc.contributor.author","Broniscer, Alberto"],["dc.contributor.author","Kieran, Mark W."],["dc.contributor.author","Minturn, Jane"],["dc.contributor.author","Comito, Melanie"],["dc.contributor.author","Broxon, Emmett"],["dc.contributor.author","Shih, Chie-Schin"],["dc.contributor.author","Khatua, Soumen"],["dc.contributor.author","Chintagumpala, Murali"],["dc.contributor.author","Carret, Anne-Sophie"],["dc.contributor.author","Hassall, Timothy"],["dc.contributor.author","Ziegler, David S."],["dc.contributor.author","Gottardo, Nick"],["dc.contributor.author","Dholaria, Hetal"],["dc.contributor.author","Lerme, Brianna"],["dc.contributor.author","Kirkendall, Jenavieve"],["dc.contributor.author","Doughman, Renee"],["dc.contributor.author","Hoffmann, Marion"],["dc.contributor.author","Wollman, Matthew"],["dc.contributor.author","O'Keefe, Rachel"],["dc.contributor.author","Benesch, Martin"],["dc.contributor.author","Gerber, Nicolas U."],["dc.contributor.author","Bailey, Simon"],["dc.contributor.author","Solanki, Guirish"],["dc.contributor.author","Massimino, Maura"],["dc.contributor.author","Biassoni, Veronica"],["dc.contributor.author","Cvrlje, Filip Jadrijevic"],["dc.contributor.author","Hulleman, Esther"],["dc.contributor.author","Drissi, Rachid"],["dc.contributor.author","Nazarian, Javad"],["dc.contributor.author","Jabado, Nada"],["dc.contributor.author","von Bueren, Andre Oscar"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Gielen, Gerrit H."],["dc.contributor.author","Sturm, Dominik"],["dc.contributor.author","Jones, David T. W."],["dc.contributor.author","Pfister, Stefan M."],["dc.contributor.author","Jones, Chris"],["dc.contributor.author","Hargrave, Darren"],["dc.contributor.author","Sanchez, Esther"],["dc.contributor.author","Bison, Brigitte"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Leach, James"],["dc.contributor.author","Jones, Blaise"],["dc.contributor.author","van Vuurden, Dannis G."],["dc.contributor.author","Kramm, Christof M."],["dc.contributor.author","Fouladi, Maryam"],["dc.date.accessioned","2018-11-07T10:13:07Z"],["dc.date.available","2018-11-07T10:13:07Z"],["dc.date.issued","2016"],["dc.identifier.isi","000379749000250"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40370"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.publisher.place","Cary"],["dc.relation.conference","17th International Symposium on Pediatric Neuro-Oncology (ISPNO)"],["dc.relation.eventlocation","Liverpool, ENGLAND"],["dc.relation.issn","1523-5866"],["dc.relation.issn","1522-8517"],["dc.title","CLINICAL, RADIOLOGICAL, AND HISTO-GENETIC CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA: A COLLABORATIVE REPORT FROM THE INTERNATIONAL AND SIOP-E DIPG REGISTRIES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Mueller, Klaus"],["dc.contributor.author","Schlamann, Annika"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Pietschmann, Sophie"],["dc.contributor.author","Kortmann, Rolf-Dieter"],["dc.contributor.author","Kramm, Christof M."],["dc.contributor.author","von Bueren, Andre Oscar"],["dc.date.accessioned","2018-11-07T09:17:48Z"],["dc.date.available","2018-11-07T09:17:48Z"],["dc.date.issued","2013"],["dc.format.extent","171"],["dc.identifier.isi","000327456200677"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28255"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.publisher.place","Cary"],["dc.relation.conference","4th Quadrennial Meeting of the World-Federation-of-Neuro-Oncology (WFNO) held in conjunction with the 18th Annual Meeting of the Society-for-Neuro-Oncology (SNO)"],["dc.relation.eventlocation","San Francisco, CA"],["dc.relation.issn","1523-5866"],["dc.relation.issn","1522-8517"],["dc.title","CRANIOSPINAL IRRADIATION WITH CONCURRENT METRONOMIC TEMOZOLOMIDE FOR THE TREATMENT OF PRIMARY METASTATIC HIGH-GRADE OR DIFFUSE INTRINSIC PONTINE GLIOMAS IN CHILDREN: EXPERIENCES FROM THE GERMAN MULTICENTER HIT-HGG 2007 TRIAL"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","34"],["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.lastpage","35"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Benesch, Martin"],["dc.contributor.author","Mynarek, Martin"],["dc.contributor.author","Mueller, Klaus"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Pfister, Stefan M."],["dc.contributor.author","Witt, Hendrik"],["dc.contributor.author","Fleischhack, Gudrun"],["dc.contributor.author","Schmid, Irene"],["dc.contributor.author","Kramm, Christof"],["dc.contributor.author","Vorwerk, Peter"],["dc.contributor.author","Beilken, Andreas"],["dc.contributor.author","Classen, Carl Friedrich"],["dc.contributor.author","Driever, Pablo Hernaiz"],["dc.contributor.author","Kropshofer, Gabriele"],["dc.contributor.author","Imschweiler, Thomas"],["dc.contributor.author","Juhnke, Bjoern-Ole"],["dc.contributor.author","Kortmann, Rolf-Dieter"],["dc.contributor.author","Rutkowski, Stefan"],["dc.contributor.author","von Hoff, Katja"],["dc.date.accessioned","2018-11-07T10:13:04Z"],["dc.date.available","2018-11-07T10:13:04Z"],["dc.date.issued","2016"],["dc.identifier.isi","000379749000131"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40365"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.publisher.place","Cary"],["dc.relation.conference","17th International Symposium on Pediatric Neuro-Oncology (ISPNO)"],["dc.relation.eventlocation","Liverpool, ENGLAND"],["dc.relation.issn","1523-5866"],["dc.relation.issn","1522-8517"],["dc.title","NEWLY DIAGNOSED METASTATIC INTRACRANIAL EPENDYMOMA IN CHILDREN: FREQUENCY, TREATMENT AND OUTCOME IN THE POPULATION BASED, PROSPECTIVE HIT-SERIES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Mueller, Klaus"],["dc.contributor.author","Hoffmann, Marion"],["dc.contributor.author","Seidel, Clemens"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Kordes, Uwe"],["dc.contributor.author","Sander, Annette"],["dc.contributor.author","Roessler, Jochen"],["dc.contributor.author","Graf, Norbert"],["dc.contributor.author","Scheithauer, Heike"],["dc.contributor.author","Kortmann, Rolf-Dieter"],["dc.contributor.author","Kramm, Christof M."],["dc.contributor.author","von Bueren, Andre Oscar"],["dc.date.accessioned","2018-11-07T09:39:22Z"],["dc.date.available","2018-11-07T09:39:22Z"],["dc.date.issued","2014"],["dc.format.extent","120"],["dc.identifier.isi","000337924200462"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33263"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.publisher.place","Cary"],["dc.relation.conference","16th International Symposium on Pediatric Neuro-Oncology (ISPNO)"],["dc.relation.eventlocation","Singapore, SINGAPORE"],["dc.relation.issn","1523-5866"],["dc.relation.issn","1522-8517"],["dc.title","SALVAGE TREATMENT OF PROGRESSIVE NON-PONTINE PEDIATRIC HIGH-GRADE GLIOMAS BY RE-IRRADIATION: PRELIMINARY EXPERIENCES FROM THE GERMAN HIT-HGG STUDY GROUP"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","123"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.lastpage","131"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Karremann, Michael"],["dc.contributor.author","Gielen, Gerrit H"],["dc.contributor.author","Hoffmann, Marion"],["dc.contributor.author","Wiese, Maria"],["dc.contributor.author","Colditz, Niclas"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Bison, Brigitte"],["dc.contributor.author","Claviez, Alexander"],["dc.contributor.author","van Vuurden, Dannis G"],["dc.contributor.author","von Bueren, André O"],["dc.contributor.author","Gessi, Marco"],["dc.contributor.author","Kühnle, Ingrid"],["dc.contributor.author","Hans, Volkmar H"],["dc.contributor.author","Benesch, Martin"],["dc.contributor.author","Sturm, Dominik"],["dc.contributor.author","Kortmann, Rolf-Dieter"],["dc.contributor.author","Waha, Andreas"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Kramm, Christof M"],["dc.date.accessioned","2020-12-10T18:19:37Z"],["dc.date.available","2020-12-10T18:19:37Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1093/neuonc/nox149"],["dc.identifier.eissn","1523-5866"],["dc.identifier.issn","1522-8517"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75312"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]