Wachter, Rolf

[["dc.bibliographiccitation.journal","European Journal of Cardiovascular Nursing"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Duengen, Hans-Dirk"],["dc.contributor.author","Putnikovic, Biljana"],["dc.contributor.author","Milicevic, P."],["dc.contributor.author","Tahirovic, E. Elvis"],["dc.contributor.author","Trippel, Tobias D."],["dc.contributor.author","Radenovic, Sara"],["dc.contributor.author","Veskovic, Jovan"],["dc.contributor.author","von Haehling, S."],["dc.contributor.author","Edelmann, F."],["dc.contributor.author","Wachter, R. Rolf"],["dc.contributor.author","Pieske, Burkert M."],["dc.contributor.author","Isenovic, E."],["dc.date.accessioned","2018-11-07T10:16:00Z"],["dc.date.available","2018-11-07T10:16:00Z"],["dc.date.issued","2016"],["dc.format.extent","S21"],["dc.identifier.isi","000374486500038"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40945"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.publisher.place","London"],["dc.relation.issn","1873-1953"],["dc.relation.issn","1474-5151"],["dc.title","Effects of beta-blocker therapy on hs-CRP levels in elderly patients with ischemic and non-ischemic heart failure: Results from the CIBIS-ELD trail"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","292"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","293"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Duengen, Hans-Dirk"],["dc.contributor.author","Gelbrich, Goetz"],["dc.contributor.author","Radenovic, Sara"],["dc.contributor.author","Tahirovic, E. Elvis"],["dc.contributor.author","Wachter, R. Rolf"],["dc.contributor.author","Veskovic, Jovan"],["dc.contributor.author","Loncar, G. Goran"],["dc.contributor.author","Apostolovic, Svetlana"],["dc.contributor.author","Pieske, Burkert M."],["dc.contributor.author","Edelmann, F."],["dc.date.accessioned","2018-11-07T10:14:44Z"],["dc.date.available","2018-11-07T10:14:44Z"],["dc.date.issued","2016"],["dc.identifier.isi","000377107502293"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40676"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1879-0844"],["dc.relation.issn","1388-9842"],["dc.title","Survival in HFpEF vs HFrEF patients after beta-blocker titration: New insights from the CIBIS-ELD trial"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Luers, Claus"],["dc.contributor.author","Edelmann, F."],["dc.contributor.author","Wachter, R. Rolf"],["dc.contributor.author","Pieske, Burkert M."],["dc.contributor.author","Mende, Meinhard"],["dc.contributor.author","Angermann, Christiane E."],["dc.contributor.author","Ertl, G."],["dc.contributor.author","Duengen, Hans-Dirk"],["dc.contributor.author","Stoerk, Stefan"],["dc.date.accessioned","2018-11-07T09:35:37Z"],["dc.date.available","2018-11-07T09:35:37Z"],["dc.date.issued","2014"],["dc.format.extent","1036"],["dc.identifier.isi","000343001306247"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.publisher.place","Oxford"],["dc.relation.conference","Congress of the European-Society-of-Cardiology (ESC)"],["dc.relation.eventlocation","Barcelona, SPAIN"],["dc.relation.issn","1522-9645"],["dc.relation.issn","0195-668X"],["dc.title","Prognostic impact of diastolic dysfunction in patients with heart failure with reduced ejection fraction: a cross-sectional analysis from the German Competence Network Heart Failure"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3027"],["dc.bibliographiccitation.issue","24"],["dc.bibliographiccitation.journal","European heart journal"],["dc.bibliographiccitation.lastpage","3036"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Schmidt-Schweda, Stephan"],["dc.contributor.author","Westermann, Dirk"],["dc.contributor.author","Post, Heiner"],["dc.contributor.author","Edelmann, Frank"],["dc.contributor.author","Kasner, Mario"],["dc.contributor.author","Lueers, Claus"],["dc.contributor.author","Steendijk, Paul"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Tschoepe, Carsten"],["dc.contributor.author","Pieske, Burkert"],["dc.date.accessioned","2017-09-07T11:46:45Z"],["dc.date.available","2017-09-07T11:46:45Z"],["dc.date.issued","2009"],["dc.description.abstract","We tested the hypothesis that, in heart failure with normal ejection fraction (HFNEF), diastolic dysfunction is accentuated at increasing heart rates, and this contributes to impaired frequency-dependent augmentation of cardiac output. In 17 patients with HFNEF (median age 69 years, 13 female) and seven age-matched control patients, systolic and diastolic function was analysed by pressure-volume loops at baseline heart rate and during atrial pacing to 100 and 120 min(-1). At baseline, relaxation was prolonged and end-diastolic left ventricular stiffness was higher in HFNEF, whereas all parameters of systolic function were not different from control patients. This resulted in smaller end-diastolic volumes, higher end-diastolic pressure, and a lower stroke volume and cardiac index in HFNEF vs. control patients. During pacing, frequency-dependent upregulation of contractility indices (+dP/dt(max) and Ees) occurred similarly in HFNEF and control patients, but frequency-dependent acceleration of relaxation (dP/dt(min)) was blunted in HFNEF. In HFNEF, end-diastolic volume and stroke volume decreased with higher heart rates while both remained unchanged in control patients. In HFNEF, frequency-dependent upregulation of cardiac output is blunted. This results from progressive volume unloading of the left ventricle due to limited relaxation reserve in combination with increased LV passive stiffness, despite preserved force-frequency relation."],["dc.identifier.doi","10.1093/eurheartj/ehp341"],["dc.identifier.gro","3143014"],["dc.identifier.isi","000272927300018"],["dc.identifier.pmid","19720638"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/482"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","0195-668X"],["dc.title","Blunted frequency-dependent upregulation of cardiac output is related to impaired relaxation in diastolic heart failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Psychosomatic Medicine"],["dc.bibliographiccitation.volume","75"],["dc.contributor.author","von Oehsen, Karima"],["dc.contributor.author","Wachter, R. Rolf"],["dc.contributor.author","Stahrenberg, Raoul"],["dc.contributor.author","Pieske, Burkert M."],["dc.contributor.author","Edelmann, Frank T."],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.date.accessioned","2018-11-07T09:26:09Z"],["dc.date.available","2018-11-07T09:26:09Z"],["dc.date.issued","2013"],["dc.format.extent","A54"],["dc.identifier.isi","000330467400174"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30234"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","71st Annual Scientific Meeting of the American-Psychosomatic-Society"],["dc.relation.eventlocation","Miami, FL"],["dc.relation.issn","1534-7796"],["dc.relation.issn","0033-3174"],["dc.title","PREDICTORS OF QUALITY OF LIFE-RESPONSE TO EXERCISE TRAINING IN DIASTOLIC HEART FAILURE"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","340"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Current Opinion in Cardiology"],["dc.bibliographiccitation.lastpage","349"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Pieske, Burkert M."],["dc.contributor.author","Wachter, R. Rolf"],["dc.date.accessioned","2018-11-07T11:13:19Z"],["dc.date.available","2018-11-07T11:13:19Z"],["dc.date.issued","2008"],["dc.description.abstract","Purpose of review Hypertension and diabetes both contribute to cardiovascular disease. The purpose of this review is to summarize novel epidemiological and clinical insights into the risk continuum of blood pressure and abnormalities in glucose metabolism for cardiovascular adverse remodelling, summarize the current mechanistic knowledge on hypertensive heart disease and diabetic cardiomyopathy, outline the effects of hypertension and diabetes on diastolic dysfunction and heart failure with normal ejection fraction, and discuss novel therapeutic aspects in these disease entities. Recent findings The prevalence of diabetes mellitus and hypertension increases in western populations and largely contributes to adverse cardiovascular remodelling and the growing number of patients with heart failure. Recently, diastolic heart failure (i.e., heart failure with normal ejection fraction) has been recognized as a major adverse manifestation of hypertension and diabetes, but convincing therapeutic strategies other than strict risk factor control are still lacking. However, due to clearer definitions and novel noninvasive diagnostic techniques for heart failure with normal ejection fraction, future studies may better define new specific therapeutic approaches. Summary New insights into the epidemiology and pathophysiology of diabetes-associated and hypertension-associated cardiac alterations may open the field for novel preventive therapeutic strategies tailored to reduce the risk of heart failure in this large population at risk."],["dc.identifier.doi","10.1097/HCO.0b013e3283031ab3"],["dc.identifier.isi","000256868200009"],["dc.identifier.pmid","18520718"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53864"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","0268-4705"],["dc.title","Impact of diabetes and hypertension on the heart"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","871"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","880"],["dc.bibliographiccitation.volume","107"],["dc.contributor.author","Haeusler, Karl Georg"],["dc.contributor.author","Gröschel, Klaus"],["dc.contributor.author","Köhrmann, Martin"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Brachmann, Johannes"],["dc.contributor.author","Böhm, Michael"],["dc.contributor.author","Diener, Hans-Christoph"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","Endres, Matthias"],["dc.contributor.author","Gerloff, Christian"],["dc.contributor.author","Huttner, Hagen B."],["dc.contributor.author","Kaps, Manfred"],["dc.contributor.author","Kirchhof, Paulus"],["dc.contributor.author","Nabavi, Darius Günther"],["dc.contributor.author","Nolte, Christian H."],["dc.contributor.author","Pfeilschifter, Waltraud"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Poli, Sven"],["dc.contributor.author","Schäbitz, Wolf Rüdiger"],["dc.contributor.author","Thomalla, Götz"],["dc.contributor.author","Veltkamp, Roland"],["dc.contributor.author","Steiner, Thorsten"],["dc.contributor.author","Laufs, Ulrich"],["dc.contributor.author","Röther, Joachim"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Schnabel, Renate"],["dc.date.accessioned","2020-12-10T14:10:21Z"],["dc.date.available","2020-12-10T14:10:21Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1007/s00392-018-1256-9"],["dc.identifier.eissn","1861-0692"],["dc.identifier.issn","1861-0684"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70736"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Expert opinion paper on atrial fibrillation detection after ischemic stroke"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e000182"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Open Heart"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Seegers, Joachim"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Grüter, Timo"],["dc.contributor.author","Ammermann, Antje"],["dc.contributor.author","Weber-Krüger, Mark"],["dc.contributor.author","Edelmann, Frank"],["dc.contributor.author","Gelbrich, Götz"],["dc.contributor.author","Binder, Lutz"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.contributor.author","Gröschel, Klaus"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Feltgen, Nicolas"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Wachter, Rolf"],["dc.date.accessioned","2017-09-07T11:52:34Z"],["dc.date.available","2017-09-07T11:52:34Z"],["dc.date.issued","2015"],["dc.identifier.doi","10.1136/openhrt-2014-000182"],["dc.identifier.gro","3144967"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13598"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/2650"],["dc.notes.intern","Crossref Import"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","public"],["dc.relation.issn","2053-3624"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.title","Natriuretic peptides for the detection of paroxysmal atrial fibrillation"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","227"],["dc.bibliographiccitation.journal","Psychoneuroendocrinology"],["dc.bibliographiccitation.lastpage","232"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.contributor.author","Chavanon, Mira-Lynn"],["dc.contributor.author","Pieske, Burkert M."],["dc.contributor.author","Wachter, R. Rolf"],["dc.contributor.author","Edelmann, Frank T."],["dc.date.accessioned","2018-11-07T09:48:37Z"],["dc.date.available","2018-11-07T09:48:37Z"],["dc.date.issued","2015"],["dc.description.abstract","Objectives: It has been postulated that patients with heart failure have a high risk of ventricular arrhythmias and sudden cardiac death resulting from anxiety-induced autonomic arousal. In the prospective and multicenter DIAST-CHF (Diagnostic Trial on Prevalence and Clinical Course of Diastolic Dysfunction and Heart Failure) study, we therefore, tested the hypothesis that adrenomedullin (ADM), a well-established predictor for cardiovascular outcome, is associated with self-rated anxiety symptoms in patients at risk of suffering from or actually with overt heart failure. Participants and measures: Study participants with risk factors for diastolic dysfunction were requested to complete the Hospital Anxiety and Depression Scale (HADS), and plasma mid-regional proadrenomedullin (MR-proADM) concentrations were measured. Results: In bivariate analysis, we found significantly lower plasma MR-proADM levels in patients with elevated HADS-anxiety scores above the clinically relevant cut-off level of >= 11 (n=118, 536 pmol/l, interquartile range [IQR] 449-626) as compared to non-anxious study participants (n =1,292, 573 pmol/l, IQR 486-702, p = 0.001). A set of multivariate models adjusted for potential confounders confirmed the negative association between self-rated anxiety symptoms and plasma MR-proADM. In similar models, no significant association was detected between HADS-depression scores and MR-proADM. Conclusions: The inverse relationship between plasma MR-proADM and anxiety observed in patients with cardiovascular risk factors supports a previous experimental study using a mutant mouse line with a brain-specific loss of ADM expression which displayed hyperactive and over-anxious behavior. Further experimental and clinical studies are warranted to test the hypothesis that also in humans ADM acts as a neuromodulator with anxiolytic properties. (C) 2015 Published by Elsevier Ltd."],["dc.identifier.doi","10.1016/j.psyneuen.2015.08.007"],["dc.identifier.isi","000365062900027"],["dc.identifier.pmid","26342564"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35344"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0306-4530"],["dc.title","Plasma mid-regional pro-adrenomedullin levels are inversely associated with anxiety but unrelated to depression: Results from the observational DIAST-CHF study in patients with cardiovascular risk factors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","59"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","ESC Heart Failure"],["dc.bibliographiccitation.lastpage","74"],["dc.bibliographiccitation.volume","1"],["dc.contributor.author","Nolte, Kathleen"],["dc.contributor.author","Schwarz, Silja"],["dc.contributor.author","Gelbrich, Götz"],["dc.contributor.author","Mensching, Steffen"],["dc.contributor.author","Siegmund, Friederike"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Düngen, Hans-Dirk"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.contributor.author","Halle, Martin"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Edelmann, Frank"],["dc.date.accessioned","2019-07-09T11:41:03Z"],["dc.date.available","2019-07-09T11:41:03Z"],["dc.date.issued","2014"],["dc.description.abstract","Background The long-term effects of exercise training (ET) in diastolic dysfunction (DD) and heart failure with preserved ejection fraction (HFpEF) are unknown. The present study compared the long-term effects of ET on exercise capacity, diastolic function, and quality of life (QoL) in patients with DD vs. HFpEF. Methods A total of n=43 patients with asymptomatic DD (n=19) or HFpEF [DD and New York Heart Association (NYHA) ≥II, n=24] and left ventricular ejection fraction ≥50% performed a combined endurance/resistance training over 6months (2–3/week) on top of usual care. Cardiopulmonary exercise testing, echocardiography, and QoL were obtained at baseline and follow-up. Results Patients were 62±8 years old (37% female). In the HFpEF group, 67% of patients were in NYHA class II (33% in NYHA III). Exercise capacity (peak oxygen consumption, peak VO2) differed at baseline (DD 29.2±8.7mL/min/kg vs. HFpEF 17.8±4.6 mL/min/kg; P=0.004). After 6months, peak VO2 increased significantly (P<0.044) to 19.7±5.8 mL/min/kg in the HFpEF group and also in the DD group (to 32.8±8.5mL/min/kg; P<0.002) with no overall difference between the groups (P=0.217). E/e′ ratio (left ventricular filling index) decreased from 12.2±3.5 to 10.1±3.0 (P<0.002) in patients with HFpEFand also in patients with DD (10.7±3.1 vs. 9.5±2.3; P=0.03; difference between groups P=0.210). In contrast, left atrial volume index decreased in the HFpEF group (P<0.001) but remained stable within the DD group (difference between groups P=0.015). After 6 months, physical QoL (Minnesota living with heart failure Questionnaire, 36-item short form health survey), general health perception, and 9-item patient health questionnaire score only improved in HFpEF (P<0.05). In contrast, vitality improved in both groups (difference between groups P=0.708). Conclusion A structured 6 months ET programme effectively improves exercise capacity and diastolic function in patients with DD and overt HFpEF. Therefore, controlled lifestylemodification with physical activity is effective both in DD and HFpEF."],["dc.identifier.doi","10.1002/ehf2.12007"],["dc.identifier.fs","610857"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11651"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58349"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1879-0844"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Effects of long-term endurance and resistance training on diastolic function, exercise capacity, and quality of life in asymptomatic diastolic dysfunction vs. heart failure with preserved ejection fraction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]