Chizhik, Anna M.

[["dc.bibliographiccitation.artnumber","204201"],["dc.bibliographiccitation.issue","20"],["dc.bibliographiccitation.journal","The Journal of Chemical Physics"],["dc.bibliographiccitation.volume","148"],["dc.contributor.author","Karedla, Narain"],["dc.contributor.author","Chizhik, Anna M."],["dc.contributor.author","Stein, Simon C"],["dc.contributor.author","Ruhlandt, Daja"],["dc.contributor.author","Gregor, Ingo"],["dc.contributor.author","Chizhik, Alexey I."],["dc.contributor.author","Enderlein, Jörg"],["dc.date.accessioned","2020-05-29T09:29:43Z"],["dc.date.available","2020-05-29T09:29:43Z"],["dc.date.issued","2018-05-28"],["dc.description.abstract","Our paper presents the first theoretical and experimental study using single-molecule Metal-Induced Energy Transfer (smMIET) for localizing single fluorescent molecules in three dimensions. Metal-Induced Energy Transfer describes the resonant energy transfer from the excited state of a fluorescent emitter to surface plasmons in a metal nanostructure. This energy transfer is strongly distance-dependent and can be used to localize an emitter along one dimension. We have used Metal-Induced Energy Transfer in the past for localizing fluorescent emitters with nanometer accuracy along the optical axis of a microscope. The combination of smMIET with single-molecule localization based super-resolution microscopy that provides nanometer lateral localization accuracy offers the prospect of achieving isotropic nanometer localization accuracy in all three spatial dimensions. We give a thorough theoretical explanation and analysis of smMIET, describe its experimental requirements, also in its combination with lateral single-molecule localization techniques, and present first proof-of-principle experiments using dye molecules immobilized on top of a silica spacer, and of dye molecules embedded in thin polymer films."],["dc.identifier.doi","10.1063/1.5027074"],["dc.identifier.pmid","29865842"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66012"],["dc.language.iso","en"],["dc.relation.eissn","1089-7690"],["dc.relation.issn","0021-9606"],["dc.title","Three-dimensional single-molecule localization with nanometer accuracy using Metal-Induced Energy Transfer (MIET) imaging"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","11839"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","ACS Nano"],["dc.bibliographiccitation.lastpage","11846"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Chizhik, Anna M."],["dc.contributor.author","Ruhlandt, Daja"],["dc.contributor.author","Pfaff, Janine"],["dc.contributor.author","Karedla, Narain"],["dc.contributor.author","Chizhik, Alexey I."],["dc.contributor.author","Gregor, Ingo"],["dc.contributor.author","Kehlenbach, Ralph H."],["dc.contributor.author","Enderlein, Jörg"],["dc.date.accessioned","2018-04-23T11:48:40Z"],["dc.date.available","2018-04-23T11:48:40Z"],["dc.date.issued","2017"],["dc.description.abstract","The nuclear envelope, comprising the inner and the outer nuclear membrane, separates the nucleus from the cytoplasm and plays a key role in cellular functions. Nuclear pore complexes (NPCs), which are embedded in the nuclear envelope, control transport of macromolecules between the two compartments. Here, using dual-color metal-induced energy transfer (MIET), we determine the axial distance between Lap2β and Nup358 as markers for the inner nuclear membrane and the cytoplasmic side of the NPC, respectively. Using MIET imaging, we reconstruct the 3D profile of the nuclear envelope over the whole basal area, with an axial resolution of a few nanometers. This result demonstrates that optical microscopy can achieve nanometer axial resolution in biological samples and without recourse to complex interferometric approaches."],["dc.identifier.doi","10.1021/acsnano.7b04671"],["dc.identifier.gro","3142097"],["dc.identifier.pmid","28921961"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/13555"],["dc.identifier.url","https://sfb1190.med.uni-goettingen.de/production/literature/publications/13"],["dc.language.iso","en"],["dc.notes.intern","lifescience updates Crossref Import"],["dc.notes.status","final"],["dc.relation","SFB 1190: Transportmaschinen und Kontaktstellen zellulärer Kompartimente"],["dc.relation","SFB 1190 | P07: Dynamik von Proteinen der inneren Kernmembran"],["dc.relation.issn","1936-0851"],["dc.relation.workinggroup","RG Kehlenbach (Nuclear Transport)"],["dc.title","Three-Dimensional Reconstruction of Nuclear Envelope Architecture Using Dual-Color Metal-Induced Energy Transfer Imaging"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","265"],["dc.bibliographiccitation.lastpage","281"],["dc.contributor.author","Karedla, Narain"],["dc.contributor.author","Ruhlandt, Daja"],["dc.contributor.author","Chizhik, Anna M."],["dc.contributor.author","Enderlein, Jörg"],["dc.contributor.author","Chizhik, Alexey I."],["dc.date.accessioned","2020-05-29T09:29:20Z"],["dc.date.available","2020-05-29T09:29:20Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1007/4243_2014_77"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66008"],["dc.relation.isbn","978-3-319-15635-4"],["dc.relation.isbn","978-3-319-15636-1"],["dc.relation.ispartof","Advanced Photon Counting"],["dc.title","Metal-Induced Energy Transfer"],["dc.type","book_chapter"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","237"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Nano Letters"],["dc.bibliographiccitation.lastpage","242"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Chizhik, Anna M."],["dc.contributor.author","Stein, Simon"],["dc.contributor.author","Dekaliuk, Mariia O."],["dc.contributor.author","Battle, Christopher"],["dc.contributor.author","Li, Weixing"],["dc.contributor.author","Huss, Anja"],["dc.contributor.author","Platen, Mitja"],["dc.contributor.author","Schaap, Iwan A. T."],["dc.contributor.author","Gregor, Ingo"],["dc.contributor.author","Demchenko, Alexander P."],["dc.contributor.author","Schmidt, Christoph F."],["dc.contributor.author","Enderlein, Jörg"],["dc.contributor.author","Chizhik, Alexey"],["dc.date.accessioned","2017-09-07T11:54:46Z"],["dc.date.available","2017-09-07T11:54:46Z"],["dc.date.issued","2016"],["dc.description.abstract","Success in super-resolution imaging relies on a proper choice of fluorescent probes. Here, we suggest novel easily produced and biocompatible nanoparticles-carbon nanodots-for super-resolution optical fluctuation bioimaging (SOFT). The particles revealed an intrinsic dual-color fluorescence, which corresponds to two subpopulations of particles of different electric charges. The neutral nanoparticles localize to cellular nuclei suggesting their potential use as an inexpensive, easily produced nucleus-specific label. The single particle study revealed that the carbon nanodots possess a unique hybrid combination of fluorescence properties exhibiting characteristics of both dye molecules and semiconductor nanocrystals. The results suggest that charge trapping and redistribution on the surface of the particles triggers their transitions between emissive and dark states. These findings open up new possibilities for the utilization of carbon nanodots in the various super-resolution microscopy methods based on stochastic optical switching."],["dc.identifier.doi","10.1021/acs.nanolett.5b03609"],["dc.identifier.gro","3141754"],["dc.identifier.isi","000368322700038"],["dc.identifier.pmid","26605640"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/702"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.eissn","1530-6992"],["dc.relation.issn","1530-6984"],["dc.title","Super-Resolution Optical Fluctuation Bio-Imaging with Dual-Color Carbon Nanodots"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1695"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Nano Letters"],["dc.bibliographiccitation.lastpage","1700"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Ghosh, Subhabrata"],["dc.contributor.author","Chizhik, Anna M."],["dc.contributor.author","Yang, Gaoling"],["dc.contributor.author","Karedla, Narain"],["dc.contributor.author","Gregor, Ingo"],["dc.contributor.author","Oron, Dan"],["dc.contributor.author","Weiss, Shimon"],["dc.contributor.author","Enderlein, Jörg"],["dc.contributor.author","Chizhik, Alexey I."],["dc.date.accessioned","2020-12-10T18:09:12Z"],["dc.date.available","2020-12-10T18:09:12Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1021/acs.nanolett.8b04695"],["dc.identifier.eissn","1530-6992"],["dc.identifier.issn","1530-6984"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73565"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Excitation and Emission Transition Dipoles of Type-II Semiconductor Nanorods"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","21306"],["dc.bibliographiccitation.issue","41"],["dc.bibliographiccitation.journal","Nanoscale"],["dc.bibliographiccitation.lastpage","21315"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Zelená, Anna"],["dc.contributor.author","Isbaner, Sebastian"],["dc.contributor.author","Ruhlandt, Daja"],["dc.contributor.author","Chizhik, Anna"],["dc.contributor.author","Cassini, Chiara"],["dc.contributor.author","Klymchenko, Andrey S."],["dc.contributor.author","Enderlein, Jörg"],["dc.contributor.author","Chizhik, Alexey"],["dc.contributor.author","Köster, Sarah"],["dc.date.accessioned","2021-04-14T08:31:45Z"],["dc.date.available","2021-04-14T08:31:45Z"],["dc.date.issued","2020"],["dc.description.abstract","Human blood platelets are non-nucleated fragments of megakaryocytes and of high importance for early hemostasis. To form a blood clot, platelets adhere to the blood vessel wall, spread and attract other platelets. Despite the importance for biomedicine, the exact mechanism of platelet spreading and adhesion to surfaces remains elusive. Here, we employ metal-induced energy transfer (MIET) imaging with a leaflet-specific fluorescent membrane probe to quantitatively determine, with nanometer resolution and in a time-resolved manner, the height profile of the basal and the apical platelet membrane above a rigid substrate during platelet spreading. We observe areas, where the platelet membrane approaches the substrate particularly closely and these areas are stable on a time scale of minutes. Time-resolved MIET measurements reveal distinct behaviors of the outermost rim and the central part of the platelets, respectively. Our findings quantify platelet adhesion and spreading and improve our understanding of early steps in blood clotting. Furthermore, the results of this study demonstrate the potential of MIET for simultaneous imaging of two close-by membranes and thus three-dimensional reconstruction of the cell shape."],["dc.identifier.doi","10.1039/d0nr05611a"],["dc.identifier.pmid","33073832"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83702"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/150"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation.eissn","2040-3372"],["dc.relation.issn","2040-3364"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Köster (Cellular Biophysics)"],["dc.relation.workinggroup","RG Enderlein"],["dc.rights","CC BY-NC 3.0"],["dc.subject.gro","cellular biophysics"],["dc.title","Time-resolved MIET measurements of blood platelet spreading and adhesion"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Thiele, Jan Christoph"],["dc.contributor.author","Jungblut, Marvin"],["dc.contributor.author","Helmerich, Dominic A."],["dc.contributor.author","Tsukanov, Roman"],["dc.contributor.author","Chizhik, Anna M."],["dc.contributor.author","Chizhik, Alexey I."],["dc.contributor.author","Schnermann, Martin"],["dc.contributor.author","Sauer, Markus"],["dc.contributor.author","Nevskyi, Oleksii"],["dc.contributor.author","Enderlein, Jörg"],["dc.date.accessioned","2022-01-12T16:50:43Z"],["dc.date.available","2022-01-12T16:50:43Z"],["dc.date.issued","2021-12-22"],["dc.description.abstract","Over the last two decades, super-resolution microscopy has seen a tremendous development in speed and resolution, but for most of its methods, there exists a remarkable gap between lateral and axial resolution. Similar to conventional optical microscopy, the axial resolution is by a factor three to five worse than the lateral resolution. One recently developed method to close this gap is metal-induced energy transfer (MIET) imaging which achieves an axial resolution down to nanometers. It exploits the distance dependent quenching of fluorescence when a fluorescent molecule is brought close to a metal surface. In the present manuscript, we combine the extreme axial resolution of MIET imaging with the extraordinary lateral resolution of single-molecule localization microscopy, in particular with direct stochastic optical reconstruction microscopy (dSTORM). This combination allows us to achieve isotropic three-dimensional super-resolution imaging of sub-cellular structures. Moreover, we employed spectral demixing for implementing dualcolor MIET-dSTORM that allows us to image and co-localize, in three dimensions, two different cellular structures simultaneously."],["dc.format.extent","16"],["dc.identifier.doi","10.1101/2021.12.20.473473"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/98094"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/378"],["dc.language.iso","en"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation.orgunit","III. Physikalisches Institut - Biophysik"],["dc.relation.workinggroup","RG Enderlein"],["dc.title","Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer"],["dc.type","preprint"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","14994"],["dc.bibliographiccitation.issue","22"],["dc.bibliographiccitation.journal","Physical Chemistry Chemical Physics"],["dc.bibliographiccitation.lastpage","15000"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Chizhik, Anna M."],["dc.contributor.author","Tarpani, Luigi"],["dc.contributor.author","Latterini, Loredana"],["dc.contributor.author","Gregor, Ingo"],["dc.contributor.author","Enderlein, Jörg"],["dc.contributor.author","Chizhik, Alexey I."],["dc.date.accessioned","2015-12-09T10:45:34Z"],["dc.date.accessioned","2021-10-11T11:34:51Z"],["dc.date.available","2015-12-09T10:45:34Z"],["dc.date.available","2021-10-11T11:34:51Z"],["dc.date.issued","2015"],["dc.description.abstract","We present the results of a comprehensive photoluminescence study of defect centres in single SiO2 nanoparticles. We show that the photo-physical properties of the luminescent centres strongly resemble those of single dye molecules. However, these properties exhibit a large variability from particle to particle due to the different local chemical environment around each centre of each particle. This variability provides new insight into the complex photo-physics of single quantum emitters embedded into a random chemical environment. Moreover, a better understanding of the fundamental mechanism of the photoluminescence of defect centres in SiO2 structure is paramount for their application as white-light sources, non-toxic labels for bio-imaging, or for combining them with metallic and semiconductor nanostructures."],["dc.identifier.citation","Chizhik, Anna M; Tarpani, Luigi; Latterini, Loredana; Gregor, Ingo; Enderlein, Jörg; Chizhik, Alexey I (2015): Photoluminescence of a single quantum emitter in a strongly inhomogeneous chemical environment. - Physical chemistry chemical physics : PCCP, Vol. 17, Nr. 22, p. 14994-5000"],["dc.identifier.doi","10.1039/c5cp01371b"],["dc.identifier.pmid","25986857"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12607"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/90707"],["dc.language","eng"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.notes.status","final"],["dc.relation.doi","10.1039/C5CP01371B"],["dc.relation.eissn","1463-9084"],["dc.relation.issn","1463-9084"],["dc.relation.issn","1463-9076"],["dc.relation.orgunit","Fakultät für Physik"],["dc.rights","CC BY 3.0"],["dc.rights.access","openAccess"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0/"],["dc.subject","Photoluminescence; quantum emitter; inhomogeneous chemical environment"],["dc.title","Photoluminescence of a single quantum emitter in a strongly inhomogeneous chemical environment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","5751"],["dc.bibliographiccitation.issue","23"],["dc.bibliographiccitation.journal","The Journal of Physical Chemistry Letters"],["dc.bibliographiccitation.lastpage","5757"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Khan, Syamantak"],["dc.contributor.author","Li, Weixing"],["dc.contributor.author","Karedla, Narain"],["dc.contributor.author","Thiart, Jan"],["dc.contributor.author","Gregor, Ingo"],["dc.contributor.author","Chizhik, Anna M."],["dc.contributor.author","Enderlein, Jörg"],["dc.contributor.author","Nandi, Chayan K."],["dc.contributor.author","Chizhik, Alexey I."],["dc.date.accessioned","2018-04-23T11:48:34Z"],["dc.date.available","2018-04-23T11:48:34Z"],["dc.date.issued","2017"],["dc.description.abstract","This study focuses on the mechanism of fluorescence blinking of single carbon nanodots, which is one of their key but less understood properties. The results of our single-particle fluorescence study show that the mechanism of carbon nanodots blinking has remarkable similarities with that of semiconductor quantum dots. In particular, the temporal behavior of carbon nanodot blinking follows a power law both at room and at cryogenic temperatures. Our experimental data suggest that static quenching via Dexter-type electron transfer between surface groups of a nanoparticle plays a major role in the transition of carbon nanodots to off or gray states, whereas the transition back to on states is governed by an electron tunneling from the particle’s core. These findings advance our understanding of the complex mechanism of carbon nanodots emission, which is one of the key steps for their application in fluorescence imaging."],["dc.identifier.doi","10.1021/acs.jpclett.7b02521"],["dc.identifier.gro","3142095"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/13533"],["dc.language.iso","en"],["dc.notes.intern","lifescience updates Crossref Import"],["dc.notes.status","final"],["dc.relation.issn","1948-7185"],["dc.title","Charge-Driven Fluorescence Blinking in Carbon Nanodots"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","5656"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Nano Letters"],["dc.bibliographiccitation.lastpage","5661"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Ghosh, Siddharth"],["dc.contributor.author","Chizhik, Anna M."],["dc.contributor.author","Karedla, Narain"],["dc.contributor.author","Dekaliuk, Mariia O."],["dc.contributor.author","Gregor, Ingo"],["dc.contributor.author","Schuhmann, Henning"],["dc.contributor.author","Seibt, Michael"],["dc.contributor.author","Bodensiek, Kai"],["dc.contributor.author","Schaap, Iwan A. T."],["dc.contributor.author","Schulz, Olaf"],["dc.contributor.author","Demchenko, Alexander P."],["dc.contributor.author","Enderlein, Jörg"],["dc.contributor.author","Chizhik, Alexey I."],["dc.date.accessioned","2018-04-23T11:49:26Z"],["dc.date.available","2018-04-23T11:49:26Z"],["dc.date.issued","2014"],["dc.description.abstract","Inorganic carbon nanomaterials, also called carbon nanodots, exhibit a strong photoluminescence with unusual properties and, thus, have been the focus of intense research. Nonetheless, the origin of their photoluminescence is still unclear and the subject of scientific debates. Here, we present a single particle comprehensive study of carbon nanodot photoluminescence, which combines emission and lifetime spectroscopy, defocused emission dipole imaging, azimuthally polarized excitation dipole scanning, nanocavity-based quantum yield measurements, high resolution transmission electron microscopy, and atomic force microscopy. We find that photoluminescent carbon nanodots behave as electric dipoles, both in absorption and emission, and that their emission originates from the recombination of photogenerated charges on defect centers involving a strong coupling between the electronic transition and collective vibrations of the lattice structure."],["dc.identifier.doi","10.1021/nl502372x"],["dc.identifier.gro","3142116"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/13696"],["dc.language.iso","en"],["dc.notes.intern","lifescience updates Crossref Import"],["dc.notes.status","final"],["dc.relation.issn","1530-6984"],["dc.title","Photoluminescence of Carbon Nanodots: Dipole Emission Centers and Electron–Phonon Coupling"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]