Meyer, Thomas J.

[["dc.bibliographiccitation.firstpage","395"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Applied Psychophysiology and Biofeedback"],["dc.bibliographiccitation.lastpage","404"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Albrecht, Juliane"],["dc.contributor.author","Bornschein, Gesine"],["dc.contributor.author","Sachsse, Ulrich"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.date.accessioned","2018-11-07T10:05:15Z"],["dc.date.available","2018-11-07T10:05:15Z"],["dc.date.issued","2016"],["dc.description.abstract","Diminished parasympathetic reactivity is a physiological feature of posttraumatic stress disorder (PTSD). The objective of this study was to compare female PTSD patients with non-traumatized healthy women with respect to autonomic cardiovascular regulation during exposure to two stressors. Hospitalized PTSD patients (n = 52) and controls (n = 37) completed standardized laboratory-based stress testing including a mental arithmetic test and a standardized audiotape recording of a crying infant. Controls and PTSD patients both showed a significantly increased heart rate and reduced pre-ejection period from baseline rest to the arithmetic stressor. However, as judged from nonsignificant changes in baroreflex sensitivity, parasympathetic activation caused by the crying infant stressor was blunted in PTSD patients as compared to healthy individuals. Under the crying infant condition, a vagal dominance was observed only in controls, and not in PTSD patients. Our data demonstrate that, in PTSD patients, diminished parasympathetic reactivity is not restricted to trauma-related events but can also be observed in response to a social stimulus such as listening to a crying infant. This finding suggests that the altered vagal reactivity in PTSD patients reflects the physiological consequences of a generally disturbed autonomous response to emotionally relevant stressors."],["dc.identifier.doi","10.1007/s10484-016-9341-1"],["dc.identifier.isi","000388970200004"],["dc.identifier.pmid","27492189"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38861"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1573-3270"],["dc.relation.issn","1090-0586"],["dc.title","Posttraumatic Stress Disorder (PTSD) Patients Exhibit a Blunted Parasympathetic Response to an Emotional Stressor"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Human Gene Therapy"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Schwanke, Kristin"],["dc.contributor.author","Haase, Alexandra"],["dc.contributor.author","Olmer, Ruth"],["dc.contributor.author","Wunderlich, Stephanie"],["dc.contributor.author","Merkert, Sylvia"],["dc.contributor.author","Gruh, Ina"],["dc.contributor.author","Zweigerdt, Robert"],["dc.contributor.author","Wagner, Stefan"],["dc.contributor.author","Maier, Lars"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Martin, Ulrich"],["dc.date.accessioned","2018-11-07T11:22:43Z"],["dc.date.available","2018-11-07T11:22:43Z"],["dc.date.issued","2009"],["dc.format.extent","1459"],["dc.identifier.isi","000271441000317"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56036"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Mary Ann Liebert Inc"],["dc.publisher.place","New rochelle"],["dc.relation.conference","Combined Meeting of the 17th European-Society-of-Gene-and-Cell-Therapy/16th German-Society-for-Gene-Therapy/4th German-Society-for-Stem-Cell-Research"],["dc.relation.eventlocation","Hannover, GERMANY"],["dc.relation.issn","1043-0342"],["dc.title","Differentiation of human cord blood-derived induced pluripotent stem (iPS) cells into functional cardiomyocytes"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Nast, Roswitha"],["dc.contributor.author","Staab, Julia"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.editor","Behzadi, Payam"],["dc.date.accessioned","2019-08-07T07:32:36Z"],["dc.date.available","2019-08-07T07:32:36Z"],["dc.date.issued","2019"],["dc.description.abstract","Signal transducers and activators of transcription (STATs) are a family of cytokine-regulated transcription factors, which serve the dual role of external signal transduction and transcriptional activation. The founding member of this family, STAT1, is involved in a plethora of cellular processes, including interferon-dependent upregulation of various effector mechanisms in immune and non-immune cells to control bacterial, fungal and parasitic infections. In this chapter, we discuss the principles of STAT1-driven gene expression and focus on the clinical phenotypes of various human STAT1 mutations. In particular, we highlight the significance of sequence-specific DNA binding and intact nucleocytoplasmic shuttling for full transcriptional activation of interferon-driven target genes."],["dc.identifier.doi","10.5772/intechopen.82699"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62332"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.relation.isbn","978-1-78985-683-5"],["dc.relation.isbn","978-1-78985-684-2"],["dc.relation.ispartof","Gene Regulation"],["dc.title","Gene Activation by the Cytokine-Driven Transcription Factor STAT1"],["dc.type","book_chapter"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","164"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Psychosomatic Medicine"],["dc.bibliographiccitation.lastpage","166"],["dc.bibliographiccitation.volume","76"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Berendes, Angela"],["dc.contributor.author","Hulpke-Wette, Martin"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.date.accessioned","2018-11-07T09:43:54Z"],["dc.date.available","2018-11-07T09:43:54Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1097/PSY.0000000000000034"],["dc.identifier.isi","000336263200010"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34279"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","1534-7796"],["dc.relation.issn","0033-3174"],["dc.title","BLOOD PRESSURE AND SCHOOL PERFORMANCE REPLY"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","A53"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Psychosomatic Medicine"],["dc.bibliographiccitation.lastpage","A54"],["dc.bibliographiccitation.volume","79"],["dc.contributor.author","Fangauf, Stella V."],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Albus, Christian"],["dc.contributor.author","Ladwig, Karl-Heinz"],["dc.contributor.author","Michal, Matthias"],["dc.contributor.author","Ronel, Joram"],["dc.contributor.author","Soellner, Wolfgang"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.date.accessioned","2018-11-07T10:24:25Z"],["dc.date.available","2018-11-07T10:24:25Z"],["dc.date.issued","2017"],["dc.identifier.isi","000401250500141"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42658"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","75th Annual Scientific Meeting on Mobilizing Technology to Advance Biobehavioral Science and Health"],["dc.relation.eventlocation","Sevilla, SPAIN"],["dc.relation.issn","1534-7796"],["dc.relation.issn","0033-3174"],["dc.title","EFFECTS OF NT-PRO BNP ON ANXIETY IN DEPRESSED PATIENTS WITH CORONARY ARTERY DISEASE (CAD)"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1818"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Journal of Medical Virology"],["dc.bibliographiccitation.lastpage","1825"],["dc.bibliographiccitation.volume","83"],["dc.contributor.author","Ruppert, Volker"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Balbach, Anna"],["dc.contributor.author","Richter, Anette"],["dc.contributor.author","Mueller, Hans-Helge"],["dc.contributor.author","Maisch, Bernhard"],["dc.contributor.author","Pankuweit, Sabine"],["dc.date.accessioned","2018-11-07T08:51:36Z"],["dc.date.available","2018-11-07T08:51:36Z"],["dc.date.issued","2011"],["dc.description.abstract","Genotype-specific effects of parvovirus B19 (B19V) infections on left ventricular function in patients with dilated cardiomyopathy (DCM) have not been investigated so far. In this prospective clinical study, the prevalences of B19V genotypes in endomyocardial biopsies from patients presenting with inflammatory heart disease and DCM were determined. A total of 139 consecutive patients were included in the study; among them 53 patients were diagnosed as DCM. Among the total study cohort, B19V DNA was detected in 65 study participants (46.8%). Genotyping of the B19V genomes in the total cohort identified genotype 1 in 38 samples (27.3%), genotype 2 in 25 samples (18.0%), and genotype 3 in only two patients (1.4%). During an average follow-up period of 8 months left ventricular ejection fraction (LVEF) improved significantly both in 819V-positive (7.1 +/- 13.8%, n = 17, P=0.038) as well as B19V-negative patients with DCM (9.5 +/- 13.9%, n = 20, P=0.017). However, mean LVEF improved only in patients with genotype 1 (11.0 +/- 14.4%, n = 7), whereas it even decreased in patients with genotype 2 (-6.2 +/- 6.3%, n = 5, P=0.033). These data from a small sample of patients diagnosed as DCM suggested that myocardial function during short-time follow-up differed between genetic variants of B19V. Patients with genotype 1 were on average younger than genotype 2 and appeared to be more prone to a beneficial course of left ventricular function than patients with genotype 2. Future studies with larger sample sizes and longer follow-up periods will be required to confirm this observation. J. Med. Virol. 83:1818-1825, 2011. (C) 2011 Wiley-Liss, Inc."],["dc.identifier.doi","10.1002/jmv.22187"],["dc.identifier.isi","000293985900020"],["dc.identifier.pmid","21837800"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21972"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0146-6615"],["dc.title","Genotype-Specific Effects on Left Ventricular Function in Parvovirus B19-Positive Patients With Dilated Cardiomyopathy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3441"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Molecular Biology and Evolution"],["dc.bibliographiccitation.lastpage","3450"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Meyer, Thomas J."],["dc.contributor.author","McLain, Adam T."],["dc.contributor.author","Oldenburg, J. Michael"],["dc.contributor.author","Faulk, Christopher"],["dc.contributor.author","Bourgeois, Matthew G."],["dc.contributor.author","Conlin, Erin M."],["dc.contributor.author","Mootnick, Alan R."],["dc.contributor.author","de Jong, Pieter J."],["dc.contributor.author","Roos, Christian"],["dc.contributor.author","Carbone, Lucia"],["dc.contributor.author","Batzer, Mark A."],["dc.date.accessioned","2022-10-06T13:35:11Z"],["dc.date.available","2022-10-06T13:35:11Z"],["dc.date.issued","2012"],["dc.identifier.doi","10.1093/molbev/mss149"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116036"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1537-1719"],["dc.relation.issn","0737-4038"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","An Alu-Based Phylogeny of Gibbons (Hylobatidae)"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","515"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of Psychosomatic Research"],["dc.bibliographiccitation.lastpage","523"],["dc.bibliographiccitation.volume","63"],["dc.contributor.author","Lache, Bernhard"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Herrmann-Lingen, Christoph"],["dc.date.accessioned","2018-11-07T10:57:13Z"],["dc.date.available","2018-11-07T10:57:13Z"],["dc.date.issued","2007"],["dc.description.abstract","Objective: Emotionally stressful events appear to trigger malignant ventricular arrhythmias and myocardial infarction in cardiac patients. However, the physiological pathways linking psychological stress to arrhythmias and adverse disease outcomes remain incompletely understood. In patients with implanted cardioverter-defibrillators (ICD) we investigated the impact of emotions and social support on cardiovascular recovery from mental stress. The hypothesis tested was that psychosocial resources help to maintain adaptive hemodynamic responses to mental stress. Methods: In 55 ICD patients we noninvasively measured hemodynamic and autonomic parameters during two sequentially performed mental stress tests (arithmetic and anger recall tests). The cardiovascular data obtained were associated with results from well-validated psychometric self-rating tests for anxiety and depression (HADS), anger (STAXI), and perceived social support (FSozU). Results: In the rest period after mental stress application the majority of the study participants (82%) showed a rapid fall in cardiac index, arterial blood pressure, and heart rate, as well as an increase in high-frequency heart rate variability, while the remainder had no or unexpected changes in the hemodynamic parameters examined. Patients missing hemodynamic recovery in the post-stress phase reported significantly less social support than normally reacting patients (P <.05). Multivariate logistic regression models confirm that social support is an independent and significant predictor of preserved hemodynamic recovery from mental stress, even after controlling for somatic confounders (multivariate odds ratio 4.1; 95% confidence interval 1.3-12.7; P=.015). Conclusions: Our data indicate that in ICD patients better perceived social support is associated with a more pronounced hemodynamic recovery after mental stress. (c) 2007 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.jpsychores.2007.06.024"],["dc.identifier.isi","000251077600010"],["dc.identifier.pmid","17980225"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50191"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0022-3999"],["dc.title","Social support predicts hemodynamic recovery from mental stress in patients with implanted defibrillators"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1516"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Neurology"],["dc.bibliographiccitation.lastpage","1525"],["dc.bibliographiccitation.volume","266"],["dc.contributor.author","Dorst, Johannes"],["dc.contributor.author","Chen, Lu"],["dc.contributor.author","Rosenbohm, Angela"],["dc.contributor.author","Dreyhaupt, Jens"],["dc.contributor.author","Hübers, Annemarie"],["dc.contributor.author","Schuster, Joachim"],["dc.contributor.author","Weishaupt, Jochen H."],["dc.contributor.author","Kassubek, Jan"],["dc.contributor.author","Gess, Burkhard"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Weyen, Ute"],["dc.contributor.author","Hermann, Andreas"],["dc.contributor.author","Winkler, Jürgen"],["dc.contributor.author","Grehl, Torsten"],["dc.contributor.author","Hagenacker, Tim"],["dc.contributor.author","Lingor, Paul"],["dc.contributor.author","Koch, Jan C."],["dc.contributor.author","Sperfeld, Anne"],["dc.contributor.author","Petri, Susanne"],["dc.contributor.author","Großkreutz, Julian"],["dc.contributor.author","Metelmann, Moritz"],["dc.contributor.author","Wolf, Joachim"],["dc.contributor.author","Winkler, Andrea S."],["dc.contributor.author","Klopstock, Thomas"],["dc.contributor.author","Boentert, Matthias"],["dc.contributor.author","Johannesen, Siw"],["dc.contributor.author","Storch, Alexander"],["dc.contributor.author","Schrank, Bertold"],["dc.contributor.author","Zeller, Daniel"],["dc.contributor.author","Liu, Xiao-lu"],["dc.contributor.author","Tang, Lu"],["dc.contributor.author","Fan, Dong-Sheng"],["dc.contributor.author","Ludolph, Albert C."],["dc.date.accessioned","2020-12-10T14:10:33Z"],["dc.date.available","2020-12-10T14:10:33Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1007/s00415-019-09290-4"],["dc.identifier.eissn","1432-1459"],["dc.identifier.issn","0340-5354"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70799"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Prognostic factors in ALS: a comparison between Germany and China"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Archives of Psychiatry and Clinical Neuroscience"],["dc.contributor.author","Stazi, Martina"],["dc.contributor.author","Zampar, Silvia"],["dc.contributor.author","Nadolny, Madeleine"],["dc.contributor.author","Büschgens, Luca"],["dc.contributor.author","Meyer, Thomas"],["dc.contributor.author","Wirths, Oliver"],["dc.date.accessioned","2022-07-01T07:35:35Z"],["dc.date.available","2022-07-01T07:35:35Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract Regular physical activity has been associated with healthy brain aging, reflected by beneficial effects on cognition and learning and memory. Nutritional supplements such as caffeine have been shown to act as cognitive enhancers and may possess neuroprotective properties. Interestingly, caffeine also improves athletic capabilities and is widely used by athletes because of its performance-enhancing effect, while information on potential additive beneficial effects of physical activity and caffeine on cognitive performance is scarce. In the present study, the effects of caffeine supplementation in combination with prolonged physical and cognitive stimulation in the form of the enriched environment (EE) housing for a duration of 4 months were analyzed. We demonstrate that caffeine supplementation together with prolonged environmental enrichment led to enhanced memory function, resulting in improved recognition and spatial working memory in behavioral paradigms such as the novel object recognition task or the Morris water maze in C57Bl6 wild-type mice. Mice housed under EE conditions showed increased gene expression levels of brain-derived neurotrophic factor (BDNF) in the hippocampus. The present findings underscore the potential impact of continuous physical activity in the prevention of age-related cognitive decline and may offer new options for combinatorial approaches."],["dc.description.sponsorship"," Alzheimer Forschung Initiative http://dx.doi.org/10.13039/100010146"],["dc.description.sponsorship"," Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659"],["dc.description.sponsorship","Gerhard Hunsmann Stiftung"],["dc.description.sponsorship"," Georg-August-Universität Göttingen 501100003385"],["dc.identifier.doi","10.1007/s00406-022-01431-7"],["dc.identifier.pii","1431"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112210"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-581"],["dc.relation.eissn","1433-8491"],["dc.relation.issn","0940-1334"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Combined long-term enriched environment and caffeine supplementation improve memory function in C57Bl6 mice"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]