Now showing 1 - 4 of 4
  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","113"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","118"],["dc.bibliographiccitation.volume","281"],["dc.contributor.author","Jewgenow, Philipp"],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Bökenkamp, Regina"],["dc.contributor.author","Hörer, Jürgen"],["dc.contributor.author","Cleuziou, Julie"],["dc.contributor.author","Foth, Rudi"],["dc.contributor.author","Horke, Alexander Paul"],["dc.contributor.author","Eicken, Andreas"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Sigler, Matthias"],["dc.date.accessioned","2020-12-10T14:24:33Z"],["dc.date.available","2020-12-10T14:24:33Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.ijcard.2019.01.095"],["dc.identifier.issn","0167-5273"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72290"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Subclinical thrombus formation in bioprosthetic pulmonary valve conduits"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2011Journal Article
    [["dc.bibliographiccitation.firstpage","398"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","404"],["dc.bibliographiccitation.volume","147"],["dc.contributor.author","Vogt, Manfred Otto"],["dc.contributor.author","Kuehn, Andreas"],["dc.contributor.author","Hoerer, Juergen"],["dc.contributor.author","Schreiber, Christian"],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Foth, Rudi"],["dc.contributor.author","Eicken, Andreas"],["dc.contributor.author","Hess, John"],["dc.contributor.author","Sigler, Matthias"],["dc.date.accessioned","2018-11-07T08:58:04Z"],["dc.date.available","2018-11-07T08:58:04Z"],["dc.date.issued","2011"],["dc.description.abstract","Background: Atrial septal defects (ASD) and persistent foramen ovale (PFO) are managed in increasing numbers by catheter interventions as an attractive alternative to surgery. Early complications have been described in clinical series whereas late complications are rare. No series are reported with clinical, echocardiographic and histological data. Methods and results: We collected clinical, echocardiographic, and histolological data of nine patients with surgically explanted devices. Occlusion devices were explanted after a mean interval of 3.4 +/- 2.4 years (range 0.9-8.3). Indications were recurrent thromboembolic events in five, residual shunt/dislocation in three, and growing mass on echocardiography despite oral anticoagulation in one patient. Two patients suffered potentially live threatening events due to coronary embolism. One of them had to be resuscitated due to ventricular fibrillation. Histologically, residues of superficial thrombus formation could be demonstrated in two of the devices. In another patient, hyperplastic tissue formation was related to a local inflammatory process but not to a thrombus as suspected by echocardiography. Conclusion: Late complications after device implantation may occur up to 8 years after device implantation and may be potentially live threatening. Echocardiographic controls should be prolonged beyond the first year after implantation and every explanted device should be histologically worked up in an experienced center. Up to now, the mechanisms of late thrombogenesis are not fully understood. Crown Copyright (C) 2009 Published by Elsevier Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.ijcard.2009.09.544"],["dc.identifier.isi","000288168000015"],["dc.identifier.pmid","19896735"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6220"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23556"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","0167-5273"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Clinical, echocardiographic and histopathologic findings in nine patients with surgically explanted ASD/PFO devices: Do we know enough about the healing process in humans?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.firstpage","124"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","131"],["dc.bibliographiccitation.volume","189"],["dc.contributor.author","Schneider, Heike"],["dc.contributor.author","Vogt, Manfred"],["dc.contributor.author","Boekenkamp, Regina"],["dc.contributor.author","Hoerer, Juergen"],["dc.contributor.author","Eicken, Andreas"],["dc.contributor.author","Foth, Rudi"],["dc.contributor.author","Kriebel, Thomas"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Sigler, Matthias"],["dc.date.accessioned","2018-11-07T09:55:52Z"],["dc.date.available","2018-11-07T09:55:52Z"],["dc.date.issued","2015"],["dc.description.abstract","Objectives: We examined interventionally implanted valved Melody conduits after surgical explantation by means of histology and immunohistochemistry and matched these findings with clinical data in order to assess in vivo biocompatibility and to identify risk factors for graft failure. Methods: 9 Melody valves had been implanted in 8 patients (pulmonary n = 7, tricuspid position n = 1). Indication for explantation included significant obstruction in 7 patients and valve insufficiency in 1 patient. 4 of 8 patients had suffered from endocarditis. Mean interval between implantation and explantation was 3.2 (1.8-5.2) years. All explants were worked up using a uniform protocol with fixation in formalin and embedding in methylmethacrylate. Results: All but one valve of the explanted Melody grafts were thin and histologically intact without any pathological findings. Complete neo-endothelialization could be demonstrated by means of immunohistochemistry. All 4 Melody valves from patients with endocarditis showed dense granulocytic infiltrations, 3 of these showed thrombotic material within the valves. Conclusion: This report covers the first series of explanted Melody valves from humans applying a uniform protocol for histopathological examination. Good biocompatibility of the Melody valves could be demonstrated after a mid-term follow-up. Factors for graft failure included endocarditis, outgrowth, and residual stenosis. These findings may have significant implications for the implant procedure as well as care of the patients during long-term follow-up. (C) 2015 Elsevier Ireland Ltd. All rights reserved."],["dc.description.sponsorship","Medtronic Inc."],["dc.identifier.doi","10.1016/j.ijcard.2015.04.067"],["dc.identifier.isi","000355108300027"],["dc.identifier.pmid","25889442"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36845"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","1874-1754"],["dc.relation.issn","0167-5273"],["dc.title","Melody transcatheter valve: Histopathology and clinical implications of nine explanted devices"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2009Conference Abstract
    [["dc.bibliographiccitation.firstpage","583"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","584"],["dc.bibliographiccitation.volume","98"],["dc.contributor.author","Vogt, M."],["dc.contributor.author","Kuehn, A."],["dc.contributor.author","Hoerer, Juergen"],["dc.contributor.author","Schreiber, Christian"],["dc.contributor.author","Schneider, H."],["dc.contributor.author","Foth, Rudi"],["dc.contributor.author","Eicken, Andreas"],["dc.contributor.author","Hess, J."],["dc.contributor.author","Sigler, Matthias"],["dc.date.accessioned","2018-11-07T11:24:37Z"],["dc.date.available","2018-11-07T11:24:37Z"],["dc.date.issued","2009"],["dc.identifier.isi","000269926600017"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56445"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Dr Dietrich Steinkopff Verlag"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0684"],["dc.title","Clinical, echocardiographic and histopathologic findings in nine patients with surgically explanted ASD/PFO devices: Do we know enough about the healing process in humans?"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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