Now showing 1 - 2 of 2
  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","2132"],["dc.bibliographiccitation.issue","20"],["dc.bibliographiccitation.journal","Neurology"],["dc.bibliographiccitation.lastpage","2138"],["dc.bibliographiccitation.volume","87"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Carstens, Per-Ole"],["dc.contributor.author","Zhang, Shuo"],["dc.contributor.author","von Fintel, Eva"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Schmidt, Jens"],["dc.date.accessioned","2020-12-10T18:41:43Z"],["dc.date.available","2020-12-10T18:41:43Z"],["dc.date.issued","2016"],["dc.description.abstract","Objective: To assess safety and feasibility of real-time (RT) MRI for evaluation of dysphagia and to compare this technique to standard assessment by flexible endoscopic evaluation of swallowing (FEES) and videofluoroscopy (VF) in a cohort of patients with inclusion body myositis (IBM). Methods: Using RT-MRI, FEES, and VF, an unselected cohort of 20 patients with IBM was studied as index disease with a uniform dysphagia. Symptoms of IBM and dysphagia were explored by standardized tools including Swallowing-Related Quality of Life Questionnaire (SWAL-QoL), IBM Functional Rating Scale, Patient-Reported Functional Assessment, and Medical Research Council Scale. Results: Dysphagia was noted in 80% of the patients and SWAL-QoL was impaired in patients with IBM compared to published reference values of healthy elderly. Swallowing in a supine position during RT-MRI was well-tolerated by all patients. RT-MRI equally revealed dysphagia compared to VF and FEES and correlated well with the SWAL-QoL. Only RT-MRI allowed precise time measurements and identification of the respective tissue morphology. The pharyngeal transit times were 2-fold longer compared to published reference values and significantly correlated with morphologic abnormalities. Conclusions: RT-MRI is safe and equally capable as VF to identify the cause of dysphagia in IBM. Advantages of RT-MRI include visualization of soft tissue, more reliable timing analysis, and lack of X-ray exposure. RT-MRI may become a routine diagnostic tool for detailed assessment of the esophagus and other moving parts of the body, facilitating longitudinal evaluations in daily practice and clinical trials."],["dc.identifier.doi","10.1212/WNL.0000000000003337"],["dc.identifier.eissn","1526-632X"],["dc.identifier.isi","000392236100014"],["dc.identifier.issn","0028-3878"],["dc.identifier.pmid","27770070"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77659"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1526-632X"],["dc.relation.issn","0028-3878"],["dc.title","Evaluation of dysphagia by novel real-time MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","5185"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","European Radiology"],["dc.bibliographiccitation.lastpage","5195"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Wienbeck, Susanne"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Luftner-Nagel, Susanne"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Surov, Alexey"],["dc.contributor.author","von Fintel, Eva"],["dc.contributor.author","Stahnke, Vera"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Fischer, Uwe"],["dc.date.accessioned","2020-12-10T14:10:11Z"],["dc.date.available","2020-12-10T14:10:11Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00330-017-4911-z"],["dc.identifier.eissn","1432-1084"],["dc.identifier.issn","0938-7994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70670"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","The role of cone-beam breast-CT for breast cancer detection relative to breast density"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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