Canis, Martin

[["dc.bibliographiccitation.firstpage","859"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK"],["dc.bibliographiccitation.lastpage","866"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Martin, Alexios"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Wolff, Hendrik Andreas"],["dc.contributor.author","Kron, Martina"],["dc.contributor.author","Matthias, Christoph"],["dc.contributor.author","Steiner, Wolfgang"],["dc.date.accessioned","2018-11-07T09:39:38Z"],["dc.date.available","2018-11-07T09:39:38Z"],["dc.date.issued","2014"],["dc.description.abstract","BackgroundThe purpose of this study was to evaluate oncological and functional results of transoral laser microsurgery (TLM) in patients with T2 and T3 glottic laryngeal squamous cell carcinoma (SCC). MethodsA retrospective chart analysis was carried out. Cases were classified into categories pT2a, pT2b, and pT3. Treatment was exclusively TLMselective neck dissection and adjuvant (chemo)radiotherapy. ResultsThree hundred ninety-one patients were treated by TLM; 142 cases were category pT2a, 127 were pT2b, and 122 were pT3. Median follow-up was 71 months. Five-year overall, recurrence-free, and disease specific survival rates were 72.2%, 76.4%, and 93.2% for pT2a tumors, 64.9%, 57.3%, and 83.9% for pT2b tumors, and 58.6%, 57.8%, and 84.1% for pT3 tumors, respectively. Larynx preservation was achieved in 93% (pT2a) and 83% (pT2b and pT3). ConclusionResults are comparable to open partial or total laryngectomy and superior to primary (chemo)radiotherapy. TLM results in a lower morbidity and superior function compared to standard treatment. (c) 2013 Wiley Periodicals, Inc. Head Neck 36: 859-866, 2014"],["dc.identifier.doi","10.1002/hed.23389"],["dc.identifier.isi","000336493200019"],["dc.identifier.pmid","23720321"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33329"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1097-0347"],["dc.relation.issn","1043-3074"],["dc.title","Transoral laser microsurgery in treatment of pT2 and pT3 glottic laryngeal squamous cell carcinoma - results of 391 patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","531"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The Laryngoscope"],["dc.bibliographiccitation.lastpage","537"],["dc.bibliographiccitation.volume","124"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Koehler, Sabrina"],["dc.contributor.author","Meyer, Alexander C."],["dc.contributor.author","Blum, Jenny"],["dc.contributor.author","Strenzke, Nicola"],["dc.contributor.author","Matthias, Christoph"],["dc.contributor.author","Canis, Martin"],["dc.date.accessioned","2018-11-07T09:44:44Z"],["dc.date.available","2018-11-07T09:44:44Z"],["dc.date.issued","2014"],["dc.description.abstract","Objectives/HypothesisTo review the results of obliteration of a preexisting mastoid cavity with abdominal fat and Vibrant Soundbridge implantation in patients with mixed hearing loss (MHL) and to compare the data with results of Vibrant Soundbridge implantation in patients with MHL without mastoid cavity and with pure sensorineural hearing loss (SNHL). Study DesignRetrospective chart analysis of 10 patients (10 ears) with MHL and preexisting mastoid cavity, 18 patients (19 ears) with MHL alone and nine patients (10 ears) with SNHL treated in one tertiary referral center. MethodsVibrant Soundbridge implantation and obliteration in case a mastoid cavity existed previously. Pure tone audiometry (average air-bone gap, average functional gain), speech audiometry (Freiburg Monosyllabic Test) and complication rate were main outcome measures. ResultsPostoperative average air-bone gap was -15.121.2 dB in patients with MHL with mastoid cavity obliteration, -7.211.4 dB in patients with MHL without mastoid cavity, and -5.7 +/- 11.2 dB in patients with SNHL. Average functional gain was 40.0 +/- 23.5 dB, 39.7 +/- 12.1 dB, and 9.5 +/- 10.6 dB. Postoperative speech discrimination rate was 77.9 +/- 20.8%, 83.3 +/- 13.6%, and 83.6 +/- 6.3%. No severe intraoperative or postoperative complications were noted. ConclusionsMastoid cavity obliteration during Vibrant Soundbridge implantation in patients with MHL and preexisting mastoid cavity is a safe procedure. The audiometric results are satisfying and comparable to those of other patient groups implanted with the same device. Level of Evidence4. Laryngoscope, 124:531-537, 2014"],["dc.description.sponsorship","MED-EL, Innsbruck, Austria"],["dc.identifier.doi","10.1002/lary.24180"],["dc.identifier.isi","000329929900041"],["dc.identifier.pmid","23918587"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34461"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1531-4995"],["dc.relation.issn","0023-852X"],["dc.title","Mastoid Cavity Obliteration and Vibrant Soundbridge Implantation for Patients With Mixed Hearing Loss"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","246"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","American Journal of Otolaryngology"],["dc.bibliographiccitation.lastpage","250"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Weiss, Bernhard G."],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Matthias, Christoph"],["dc.contributor.author","Canis, Martin"],["dc.date.accessioned","2018-11-07T09:43:07Z"],["dc.date.available","2018-11-07T09:43:07Z"],["dc.date.issued","2014"],["dc.description.abstract","After laryngectomy or lateral pharyngotomy for treatment of laryngeal or hypopharyngeal cancer the occurrence of a pharyngo-cutaneous fistula is a challenging complication. Especially after previous radiotherapy and expanded surgical resections of mucosa the management is demanding. Besides the prolonged hospital stay, increased treatment costs and reduced quality of life, a delayed adjuvant treatment follows the development of a fistula. Treatment strategies range from conservative procedures comprising parenteral nutrition, antibiotics and local wound care to primary surgical closure or reconstructive tissue transfer. We report three cases of using the fibrin/thrombin-coated collagen patch TachoSil (R) as a solitary or adjuvant strategy in surgical treatment. In one patient primary closure of the fistula was achieved by transoral application of the collagen patch. In the other cases a not tension free primary suture was strengthened by the adjuvant use of TachoSil (R). The healing process was rapid and straightforward in all patients. The use of TachoSil (R) may be indicated in between conservative treatment strategies and reconstructive surgery. After occurrence of a fistula the healing process is intended to be accelerated by primary closure with TachoSil (R) or by sealing of a primary suture. (C) 2014 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.amjoto.2013.11.005"],["dc.identifier.isi","000333541800031"],["dc.identifier.pmid","24315631"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34107"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","W B Saunders Co-elsevier Inc"],["dc.relation.issn","1532-818X"],["dc.relation.issn","0196-0709"],["dc.title","Coated collagen patches for closure of pharyngo-cutaneous fistulas"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2719"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","European Archives of Oto-Rhino-Laryngology"],["dc.bibliographiccitation.lastpage","2727"],["dc.bibliographiccitation.volume","270"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Martin, Alexios"],["dc.contributor.author","Wolff, Hendrik Andreas"],["dc.contributor.author","Matthias, Christoph"],["dc.contributor.author","Steiner, Wolfgang"],["dc.date.accessioned","2018-11-07T09:20:45Z"],["dc.date.available","2018-11-07T09:20:45Z"],["dc.date.issued","2013"],["dc.description.abstract","The main objective of this study is to assess the feasibility of transoral laser microsurgery (TLM) in the treatment of T4a laryngeal cancer and to report the oncological and functional outcomes. This is a retrospective case-series study, held in a single-institute, academic tertiary referral center. Seventy-nine patients with previously untreated T4a glottic (n = 31, 39 %) or supraglottic laryngeal carcinoma (n = 48, 61 %) were included in this study. Five patients (6 %) were treated exclusively by TLM, 16 (20 %) had TLM and unilateral neck dissection, 27 (35 %) had TLM and bilateral neck dissection. Adjuvant (chemo)radiotherapy was additionally administered in 26 (33 %) cases following TLM and neck dissection, and in 5 (6 %) cases after TLM without neck dissection. The main outcome measures included organ preservation, local control, functional outcome, overall, recurrence-free, and disease-specific survival. The median follow-up period was 49 months, 5 year organ preservation rate and local control rate were 80.0 and 67.2 %, 5 year overall, recurrence-free and disease-specific survival were 55.8, 61.9 and 71.8 %. The 5 year overall survival rates were 62.5 % in pN0 cases and 57.2 % in cases with pN-positive neck disease. With respect to survival, these results are comparable to total laryngectomy, while being superior to primary (chemo)radiotherapy. TLM results in a low morbidity, rapid recovery and good function and can be a valid option for organ preserving surgery of pT4a glottic and supraglottic cancer."],["dc.identifier.doi","10.1007/s00405-013-2382-7"],["dc.identifier.isi","000323739100020"],["dc.identifier.pmid","23408021"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10308"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28952"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0937-4477"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Organ preservation in T4a laryngeal cancer: is transoral laser microsurgery an option?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","889"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK"],["dc.bibliographiccitation.lastpage","895"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Martin, Alexios"],["dc.contributor.author","Matthias, Christoph"],["dc.contributor.author","Steiner, Wolfgang"],["dc.date.accessioned","2018-11-07T09:56:40Z"],["dc.date.available","2018-11-07T09:56:40Z"],["dc.date.issued","2015"],["dc.description.abstract","BackgroundVarious therapeutic options exist for treatment of T1a glottic squamous cell cancer (SCC). Radiotherapy (RT) has been favored over surgical excision. This has been challenged by transoral laser microsurgery (TLM) showing low morbidity and good functional results. MethodsA retrospective chart review was carried out. Patients with untreated T1a glottic SCC were included in the study. Endpoints were locoregional control, overall survival, disease-specific survival, and absolute rate of larynx preservation. ResultsFour hundred four patients were included in this study. Five-year Kaplan-Meier estimates were: local control 86.8%, overall survival 87.8%, disease-specific survival 98.0%, recurrence-free survival 76.1%, and larynx preservation 97.3%. The complication rate was 1%; the majority of patients had either normal or mildly dysphonic voices. ConclusionLow complication rates, excellent functional outcome, and high rates of organ preservation favor TLM. In agreement with the literature, TLM should be the treatment of choice for patients presenting with T1a glottic SCC. (c) 2014 Wiley Periodicals, Inc. Head Neck 37: 889-895, 2015"],["dc.identifier.doi","10.1002/hed.23688"],["dc.identifier.isi","000355012000021"],["dc.identifier.pmid","24623709"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37008"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1097-0347"],["dc.relation.issn","1043-3074"],["dc.title","Transoral laser microsurgery for T1a glottic cancer: Review of 404 cases"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","HNO"],["dc.bibliographiccitation.volume","60"],["dc.contributor.author","Ihler, F."],["dc.contributor.author","Laskawi, Rainer"],["dc.contributor.author","Matthias, Christoph"],["dc.contributor.author","Rustenbeck, Hans Heino"],["dc.contributor.author","Canis, Martin"],["dc.date.accessioned","2018-11-07T09:05:10Z"],["dc.date.available","2018-11-07T09:05:10Z"],["dc.date.issued","2012"],["dc.format.extent","905"],["dc.identifier.doi","10.1007/s00106-012-2603-1"],["dc.identifier.isi","000309480200010"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25259"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0017-6192"],["dc.title","Use of Botulinum Toxin A after microvascular ALT Flaps in a patient with Tongue and Floor of mouth carcinoma (vol 60, pg 524, 2012)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","156"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK"],["dc.bibliographiccitation.lastpage","161"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Wolff, Hendrik Andreas"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Matthias, Christoph"],["dc.contributor.author","Steiner, Wolfgang"],["dc.date.accessioned","2018-11-07T10:01:43Z"],["dc.date.available","2018-11-07T10:01:43Z"],["dc.date.issued","2015"],["dc.description.abstract","BackgroundThe purpose of this study was to evaluate oncologic outcomes of transoral laser microsurgery (TLM) in patients with cancer of the oropharyngeal and/or hypopharyngeal posterior wall. MethodsBetween August 1986 and December 2006, 25 patients (oropharyngeal n=12; hypopharyngeal n=13) were treated by primary CO2 laser microsurgery. Treatment was exclusively TLM with or without selective neck dissection in 12 cases (48%); TLM with adjuvant (chemo)radiotherapy was performed in 13 cases (52%). ResultsData were analyzed by using the Kaplan-Meier method. The median follow-up was 41.6 months. The 5-year overall, recurrence-free, and disease-specific survival rates for stages I/II were 36,5%, 60,0%, and 87,5% and for stages III/IVa 41,2%, 36,4%, and 56,3%, respectively. ConclusionWith respect to local control and survival, results are comparable to conventional surgery. (c) 2014 Wiley Periodicals, Inc. Head Neck37: 156-161, 2015"],["dc.identifier.doi","10.1002/hed.23571"],["dc.identifier.isi","000348548700007"],["dc.identifier.pmid","24519973"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38080"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1097-0347"],["dc.relation.issn","1043-3074"],["dc.title","Oncologic results of transoral laser microsurgery for squamous cell carcinoma of the posterior pharyngeal wall"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1038"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","HNO"],["dc.bibliographiccitation.lastpage","1044"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Canis, Martin"],["dc.contributor.author","Ihler, F."],["dc.contributor.author","Blum, Jenny"],["dc.contributor.author","Matthias, Christoph"],["dc.date.accessioned","2018-11-07T09:17:07Z"],["dc.date.available","2018-11-07T09:17:07Z"],["dc.date.issued","2013"],["dc.description.abstract","The Bonebridge is an active bone conduction implant (BCI) that is primarily indicated in patients with conductive and combined hearing loss. However, many of these patients present with a radical cavity as a result of previous surgery. In these cases, the implant should not be introduced into the mastoid region, but rather via a retrosigmoid approach to maintain separation from the pathological alteration. To ensure the best possible acoustic transduction, the Bone Conduction-Floating Mass Transducer (BC-FMT) should be positioned near to the cochlea. This requires precise identification of the sigmoid sinus, which cannot be achieved accurately enough using external anatomical landmarks. We thus report on two patients in whom the Bonebridge was implanted via a retrosigmoid approach using CT-guided navigation."],["dc.identifier.doi","10.1007/s00106-012-2652-5"],["dc.identifier.isi","000328261100008"],["dc.identifier.pmid","23463412"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28085"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1433-0458"],["dc.relation.issn","0017-6192"],["dc.title","CT-assisted navigation for retrosigmoidal implantation of the Bonebridge"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","524"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","HNO"],["dc.bibliographiccitation.lastpage","527"],["dc.bibliographiccitation.volume","60"],["dc.contributor.author","Ihler, F."],["dc.contributor.author","Laskawi, Rainer"],["dc.contributor.author","Matthias, Christoph"],["dc.contributor.author","Rustenbeck, Hans Heino"],["dc.contributor.author","Canis, Martin"],["dc.date.accessioned","2018-11-07T09:09:48Z"],["dc.date.available","2018-11-07T09:09:48Z"],["dc.date.issued","2012"],["dc.description.abstract","We report the case of a 23-year-old man presenting with a cT4 cN1 M0squamous cell carcinoma of the right tongue. After tumor resection and covering of the defect with a microvascular anterolateral thigh (ALT) flap, the patient showed distinct drooling without any substantial regression after anticholinergic therapy. For this reason 75 units of BotoxA (R) were injected into the submandibular and parotid glands. After the intraglandular injections, good reduction of saliva secretion was achieved. The treatment improved flap healing, aspiration and patient satisfaction. Injection of botulinum toxin A into the salivary glands is a sufficient therapy for postoperative hypersalivation."],["dc.identifier.doi","10.1007/s00106-011-2476-8"],["dc.identifier.isi","000304876600010"],["dc.identifier.pmid","22534678"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26347"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0017-6192"],["dc.title","Botulinum toxin A after microvascular ALT flap in a patient with squamous cell carcinoma of the tongue"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","810"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","International Journal of Audiology"],["dc.bibliographiccitation.lastpage","816"],["dc.bibliographiccitation.volume","53"],["dc.contributor.author","Ihler, Friedrich"],["dc.contributor.author","Pelz, Sabrina"],["dc.contributor.author","Coors, Melanie"],["dc.contributor.author","Matthias, Christoph"],["dc.contributor.author","Canis, Martin"],["dc.date.accessioned","2018-11-07T09:33:14Z"],["dc.date.available","2018-11-07T09:33:14Z"],["dc.date.issued","2014"],["dc.description.abstract","Objective: Cochlear implantation trauma causes both macroscopic and inflammatory trauma. The aim of the present study was to evaluate the effectiveness of the TNF-alpha inhibitor etanercept applied after cochlear implantation trauma on the preservation of acoustic hearing. Design: Guinea pigs were randomly assigned to three groups receiving cochlear implantation trauma by cochleostomy. In one group, the site was sealed by bone cement with no further treatment. A second group was additionally implanted with an osmotic minipump delivering artificial perilymph into the scala tympani for seven days. In the third group, etanercept 1 mg/ml was added to artificial perilymph. Hearing was assessed by auditory brainstem responses at 2, 4, 6, and 8 kHz prior to and after surgery and on days 3, 5, 7, 14, 28. Study sample: Fifteen healthy guinea pigs. Results: The trauma led to threshold shifts from 50.3 dB +/- 16.3 dB to 68.0 dB +/- 19.3 dB. Hearing thresholds were significantly lower in etanercept-treated animals compared to controls on day 28 at 8 kHz and from day 3 onwards at 4 and 2 kHz (p < 0.01; two-way RM ANOVA / Bonferroni t-test). Conclusion: The application of etanercept led to preservation of acoustic hearing after cochlear implantation trauma."],["dc.identifier.doi","10.3109/14992027.2014.938369"],["dc.identifier.isi","000343928200004"],["dc.identifier.pmid","25311100"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31923"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Informa Healthcare"],["dc.relation.issn","1708-8186"],["dc.relation.issn","1499-2027"],["dc.title","Application of a TNF-alpha-inhibitor into the scala tympany after cochlear electrode insertion trauma in guinea pigs: Preliminary audiologic results"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]