Marschollek, Michael

[["dc.bibliographiccitation.firstpage","749"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Life"],["dc.bibliographiccitation.volume","12"],["dc.contributor.affiliation","Sommer, Kim K.; 1Peter L. Reichertz Institute for Medical Informatics, TU Braunschweig and Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany; sommer.kimkatrin@mh-hannover.de (K.K.S.); gietzelt.matthias@mh-hannover.de (M.G.); marschollek.michael@mh-hannover.de (M.M.)"],["dc.contributor.affiliation","Amr, Ali; 2Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany; ali.amr@med.uni-heidelberg.de (A.A.); a-kindermann@gmx.net (A.K.); benjamin.meder@med.uni-heidelberg.de (B.M.); philipp.schneider@uni-heidelberg.de (P.S.)"],["dc.contributor.affiliation","Bavendiek, Udo; 4Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Straße, 130625 Hannover, Germany; bavendiek.udo@mh-hannover.de"],["dc.contributor.affiliation","Beierle, Felix; 5Institute of Clinical Epidemiology and Biometry, University of Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany; felix.beierle@uni-wuerzburg.de (F.B.); peter.heuschmann@uni-wuerzburg.de (P.H.); pryss_r@ukw.de (R.P.)"],["dc.contributor.affiliation","Brunecker, Peter; 6Core Facility IT, Berlin Institute of Health at Charité—Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany; peter.brunecker@charite.de (P.B.); jennifer.hoos@charite.de (J.D.E.H.)"],["dc.contributor.affiliation","Dathe, Henning; 8Department of Medical Informatics, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany; henning.dathe@med.uni-goettingen.de (H.D.); tibor.kesztyues@med.uni-goettingen.de (T.K.); dagmar.krefting@med.uni-goettingen.de (D.K.); jendrik.richter@med.uni-goettingen.de (J.R.)"],["dc.contributor.affiliation","Eils, Jürgen; 9Center Digital Health, Berlin Institute of Health at Charité—Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany; juergen.eils@charite.de"],["dc.contributor.affiliation","Ertl, Maximilian; 10Datenintegrationszentrum (DIZ), Servicezentrum Informatik (SMI), Universitätsklinikum Würzburg (UKW), Schweinfurter Strasse 4, 97078 Würzburg, Germany; ertl_m@ukw.de (M.E.); georg.fette@uni-wuerzburg.de (G.F.)"],["dc.contributor.affiliation","Fette, Georg; 10Datenintegrationszentrum (DIZ), Servicezentrum Informatik (SMI), Universitätsklinikum Würzburg (UKW), Schweinfurter Strasse 4, 97078 Würzburg, Germany; ertl_m@ukw.de (M.E.); georg.fette@uni-wuerzburg.de (G.F.)"],["dc.contributor.affiliation","Gietzelt, Matthias; 1Peter L. Reichertz Institute for Medical Informatics, TU Braunschweig and Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany; sommer.kimkatrin@mh-hannover.de (K.K.S.); gietzelt.matthias@mh-hannover.de (M.G.); marschollek.michael@mh-hannover.de (M.M.)"],["dc.contributor.affiliation","Heidecker, Bettina; 11Medizinische Klinik für Kardiologie, Charité—Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany; bettina.heidecker@charite.de (B.H.); ulf.landmesser@charite.de (U.L.)"],["dc.contributor.affiliation","Hellenkamp, Kristian; 12Department of Cardiology and Pneumology/Heart Center, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany; kristian.hellenkamp@med.uni-goettingen.de"],["dc.contributor.affiliation","Heuschmann, Peter; 5Institute of Clinical Epidemiology and Biometry, University of Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany; felix.beierle@uni-wuerzburg.de (F.B.); peter.heuschmann@uni-wuerzburg.de (P.H.); pryss_r@ukw.de (R.P.)"],["dc.contributor.affiliation","Hoos, Jennifer D. E.; 6Core Facility IT, Berlin Institute of Health at Charité—Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany; peter.brunecker@charite.de (P.B.); jennifer.hoos@charite.de (J.D.E.H.)"],["dc.contributor.affiliation","Kesztyüs, Tibor; 8Department of Medical Informatics, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany; henning.dathe@med.uni-goettingen.de (H.D.); tibor.kesztyues@med.uni-goettingen.de (T.K.); dagmar.krefting@med.uni-goettingen.de (D.K.); jendrik.richter@med.uni-goettingen.de (J.R.)"],["dc.contributor.affiliation","Kerwagen, Fabian; 13Department Klinische Forschung und Epidemiologie, Deutsches Zentrum für Herzinsuffizienz, Am Schwarzenberg 15, 97078 Würzburg, Germany; kerwagen_f@ukw.de (F.K.); stoerk_s@ukw.de (S.S.)"],["dc.contributor.affiliation","Kindermann, Aljoscha; 2Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany; ali.amr@med.uni-heidelberg.de (A.A.); a-kindermann@gmx.net (A.K.); benjamin.meder@med.uni-heidelberg.de (B.M.); philipp.schneider@uni-heidelberg.de (P.S.)"],["dc.contributor.affiliation","Krefting, Dagmar; 8Department of Medical Informatics, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany; henning.dathe@med.uni-goettingen.de (H.D.); tibor.kesztyues@med.uni-goettingen.de (T.K.); dagmar.krefting@med.uni-goettingen.de (D.K.); jendrik.richter@med.uni-goettingen.de (J.R.)"],["dc.contributor.affiliation","Landmesser, Ulf; 11Medizinische Klinik für Kardiologie, Charité—Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany; bettina.heidecker@charite.de (B.H.); ulf.landmesser@charite.de (U.L.)"],["dc.contributor.affiliation","Marschollek, Michael; 1Peter L. Reichertz Institute for Medical Informatics, TU Braunschweig and Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany; sommer.kimkatrin@mh-hannover.de (K.K.S.); gietzelt.matthias@mh-hannover.de (M.G.); marschollek.michael@mh-hannover.de (M.M.)"],["dc.contributor.affiliation","Meder, Benjamin; 2Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany; ali.amr@med.uni-heidelberg.de (A.A.); a-kindermann@gmx.net (A.K.); benjamin.meder@med.uni-heidelberg.de (B.M.); philipp.schneider@uni-heidelberg.de (P.S.)"],["dc.contributor.affiliation","Merzweiler, Angela; 17Institute of Medical Informatics, Heidelberg University Hospital, Im Neuenheimer Feld 130.3, 69120 Heidelberg, Germany; angela.merzweiler@med.uni-heidelberg.de"],["dc.contributor.affiliation","Prasser, Fabian; 18Medical Informatics Group, Berlin Institute of Health at Charité—Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany; fabian.prasser@bih-charite.de"],["dc.contributor.affiliation","Pryss, Rüdiger; 5Institute of Clinical Epidemiology and Biometry, University of Würzburg, Am Schwarzenberg 15, 97078 Würzburg, Germany; felix.beierle@uni-wuerzburg.de (F.B.); peter.heuschmann@uni-wuerzburg.de (P.H.); pryss_r@ukw.de (R.P.)"],["dc.contributor.affiliation","Richter, Jendrik; 8Department of Medical Informatics, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany; henning.dathe@med.uni-goettingen.de (H.D.); tibor.kesztyues@med.uni-goettingen.de (T.K.); dagmar.krefting@med.uni-goettingen.de (D.K.); jendrik.richter@med.uni-goettingen.de (J.R.)"],["dc.contributor.affiliation","Schneider, Philipp; 2Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany; ali.amr@med.uni-heidelberg.de (A.A.); a-kindermann@gmx.net (A.K.); benjamin.meder@med.uni-heidelberg.de (B.M.); philipp.schneider@uni-heidelberg.de (P.S.)"],["dc.contributor.affiliation","Störk, Stefan; 13Department Klinische Forschung und Epidemiologie, Deutsches Zentrum für Herzinsuffizienz, Am Schwarzenberg 15, 97078 Würzburg, Germany; kerwagen_f@ukw.de (F.K.); stoerk_s@ukw.de (S.S.)"],["dc.contributor.affiliation","Dieterich, Christoph; 2Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany; ali.amr@med.uni-heidelberg.de (A.A.); a-kindermann@gmx.net (A.K.); benjamin.meder@med.uni-heidelberg.de (B.M.); philipp.schneider@uni-heidelberg.de (P.S.)"],["dc.contributor.author","Sommer, Kim K."],["dc.contributor.author","Amr, Ali"],["dc.contributor.author","Bavendiek, Udo"],["dc.contributor.author","Beierle, Felix"],["dc.contributor.author","Brunecker, Peter"],["dc.contributor.author","Dathe, Henning"],["dc.contributor.author","Eils, Jürgen"],["dc.contributor.author","Ertl, Maximilian"],["dc.contributor.author","Fette, Georg"],["dc.contributor.author","Gietzelt, Matthias"],["dc.contributor.author","Dieterich, Christoph"],["dc.contributor.author","Heidecker, Bettina"],["dc.contributor.author","Hellenkamp, Kristian"],["dc.contributor.author","Heuschmann, Peter"],["dc.contributor.author","Hoos, Jennifer D. E."],["dc.contributor.author","Kesztyüs, Tibor"],["dc.contributor.author","Kerwagen, Fabian"],["dc.contributor.author","Kindermann, Aljoscha"],["dc.contributor.author","Krefting, Dagmar"],["dc.contributor.author","Landmesser, Ulf"],["dc.contributor.author","Marschollek, Michael"],["dc.contributor.author","Meder, Benjamin"],["dc.contributor.author","Merzweiler, Angela"],["dc.contributor.author","Prasser, Fabian"],["dc.contributor.author","Pryss, Rüdiger"],["dc.contributor.author","Richter, Jendrik"],["dc.contributor.author","Schneider, Philipp"],["dc.contributor.author","Störk, Stefan"],["dc.date.accessioned","2022-06-01T09:39:59Z"],["dc.date.available","2022-06-01T09:39:59Z"],["dc.date.issued","2022"],["dc.date.updated","2022-06-05T22:44:40Z"],["dc.description.abstract","Risk prediction in patients with heart failure (HF) is essential to improve the tailoring of preventive, diagnostic, and therapeutic strategies for the individual patient, and effectively use health care resources. Risk scores derived from controlled clinical studies can be used to calculate the risk of mortality and HF hospitalizations. However, these scores are poorly implemented into routine care, predominantly because their calculation requires considerable efforts in practice and necessary data often are not available in an interoperable format. In this work, we demonstrate the feasibility of a multi-site solution to derive and calculate two exemplary HF scores from clinical routine data (MAGGIC score with six continuous and eight categorical variables; Barcelona Bio-HF score with five continuous and six categorical variables). Within HiGHmed, a German Medical Informatics Initiative consortium, we implemented an interoperable solution, collecting a harmonized HF-phenotypic core data set (CDS) within the openEHR framework. Our approach minimizes the need for manual data entry by automatically retrieving data from primary systems. We show, across five participating medical centers, that the implemented structures to execute dedicated data queries, followed by harmonized data processing and score calculation, work well in practice. In summary, we demonstrated the feasibility of clinical routine data usage across multiple partner sites to compute HF risk scores. This solution can be extended to a large spectrum of applications in clinical care."],["dc.description.sponsorship","the Federal Ministry of Education and Research (BMBF)"],["dc.identifier.doi","10.3390/life12050749"],["dc.identifier.pii","life12050749"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108610"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.eissn","2075-1729"],["dc.title","Structured, Harmonized, and Interoperable Integration of Clinical Routine Data to Compute Heart Failure Risk Scores"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]