Olthoff, Arno

[["dc.bibliographiccitation.firstpage","918"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","The Laryngoscope"],["dc.bibliographiccitation.lastpage","922"],["dc.bibliographiccitation.volume","114"],["dc.contributor.author","Rodel, RMW"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Tergau, Frithjof"],["dc.contributor.author","Simonyan, K."],["dc.contributor.author","Kraemer, Doris"],["dc.contributor.author","Markus, H."],["dc.contributor.author","Kruse, Eberhard"],["dc.date.accessioned","2018-11-07T10:49:22Z"],["dc.date.available","2018-11-07T10:49:22Z"],["dc.date.issued","2004"],["dc.description.abstract","Objectives: To analyze characteristic features and details on motor-evoked potentials (MEPs) of the cricothyroid and vocalis muscles from single-pulse cortical transcranial magnetic stimulation (TMS) in normal subjects to characterize cortical motor representation of laryngeal muscles. Study Design: Prospective, experimental investigation on healthy volunteers. Method: MEPs of the cricothyroid and vocalis muscles elicited by cortical TMS with a figure-8-shaped coil were investigated in two groups of six healthy subjects each, with special regard to MEP amplitude as a function of the coil position on the head surface along the interaural line. Results: Bilateral reproducible responses of the cricothyroid and the vocalis muscles could be observed in all subjects. For the cricothyroid muscle, maximal responses were obtained at mean stimulus positions of 7.5 +/- 1.4 cm (contralateral) and of 7.3 +/- 1.3 cm (ipsilateral), respectively. For the vocalis muscle, we found maximal responses at mean stimulus positions of 10.3 +/- 1.9 cm (contralateral) and of 9.6 +/- 1.6 cm (ipsilateral), respectively. Despite a considerable overlap of these coil positions, from which reproducible MEPs could be elicited in both groups of the laryngeal muscles, statistically significant separation of the cricothyroid- and vocalis-associated cortical representation areas was possible. Conclusions: Our observations point to two different cortical motor representation areas, with the cricothyroid muscle-related area being located more medially."],["dc.identifier.isi","000221537900026"],["dc.identifier.pmid","15126757"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/48414"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","20th Scientific Meeting of the German-Society-of-Phoniatrics-and-Pedaudiology"],["dc.relation.eventlocation","Rostock, GERMANY"],["dc.relation.issn","0023-852X"],["dc.title","Human cortical motor representation of the larynx as assessed by transcranial magnetic stimulation (TMS)"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2091"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","The Laryngoscope"],["dc.bibliographiccitation.lastpage","2096"],["dc.bibliographiccitation.volume","118"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Baudewig, Juergen"],["dc.contributor.author","Kruse, Eberhard"],["dc.contributor.author","Dechent, Peter"],["dc.date.accessioned","2018-11-07T11:09:38Z"],["dc.date.available","2018-11-07T11:09:38Z"],["dc.date.issued","2008"],["dc.description.abstract","Background: Verbal communication is a human feature and volitional vocalization is its basis. However, little is known regarding the cortical areas involved in human vocalization. Methods: Therefore, functional magnetic resonance imaging at 3 Tesla was performed in 16 healthy adults to evaluate brain activations related to voice production. The main experiments included tasks involving motor control of laryngeal muscles with and without intonation. In addition, reference mappings of the sensorimotor hand area and the auditory cortices were performed. Results: Related to vocalization, in addition to activation of the most lateral aspect of the primary sensorimotor cortex close to the Sylvian fissure (M1c), we found activations medially (M1a) and laterally (M1b) of the well-known sensorimotor hand area. Moreover, the supplementary motor area and the anterior cingulate cortex were activated. Conclusions: Although M1a could be ascribed to motor control of breathing, M1b has been associated with laryngeal motor control. Consequently, even though M1c represents a laryngeal sensorimotor area, its exclusiveness as suggested previously could not be confirmed. Activations in the supplementary motor area and anterior cingulate cortex were ascribed to \"vocal-motor planning.\" The present data provide the basis for further functional magnetic resonance imaging studies in patients with neurological laryngeal disorders."],["dc.identifier.doi","10.1097/MLG.0b013e31817fd40f"],["dc.identifier.isi","000260874700035"],["dc.identifier.pmid","18758379"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53051"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","22nd Scientific Meeting of the German-Society-of-Phoniatrics-and-Pedaudiology"],["dc.relation.eventlocation","Berlin, GERMANY"],["dc.relation.issn","0023-852X"],["dc.title","Cortical Sensorimotor Control in Vocalization: A Functional Magnetic Resonance Imaging Study"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1123"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","The Laryngoscope"],["dc.bibliographiccitation.lastpage","1126"],["dc.bibliographiccitation.volume","117"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Woywod, Christina"],["dc.contributor.author","Kruse, Eberhard"],["dc.date.accessioned","2018-11-07T11:02:00Z"],["dc.date.available","2018-11-07T11:02:00Z"],["dc.date.issued","2007"],["dc.description.abstract","Objectives: To evaluate and to compare the diagnostic value of videostroboscopy (VS) and high-speed glottography (HGG) in dysphonic patients. Study Design: Randomized, prospective study. Methods: A total of 162 patients underwent indirect laryngoscopy using both methods (VS and HGG). The resulting 324 films were evaluated by two professionals (laryngologists, MDs) using a standardized protocol containing established criteria to classify vocal fold vibratory movement qualities. Results: The rating \"not assessable\" was mentioned significantly more often in VS than in HGG (P <.001). In HGG, methodologic failures were less frequent, and the length of investigation was shorter. Even if the agreement between the two raters was higher in HGG (54%) compared with VS (42%, both percentage values show a low accordance in diagnostic findings. Conclusions: Regardless of the method used (VS or HGG), perceptive evaluations of vibratory movements of vocal folds revealed a higher variability than assumed. This result supports the need for objective methods to analyze vocal fold vibratory movements. Therefore, realtime imaging of vocal fold vibratory movements using HGG will be necessary."],["dc.identifier.doi","10.1097/MLG.0b013e318041f70c"],["dc.identifier.isi","000246925000033"],["dc.identifier.pmid","17545874"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51281"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","0023-852X"],["dc.title","Stroboscopy versus high-speed glottography: A comparative study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","599"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Annals of Otology Rhinology & Laryngology"],["dc.bibliographiccitation.lastpage","604"],["dc.bibliographiccitation.volume","114"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Zeiss, D."],["dc.contributor.author","Laskawi, Rainer"],["dc.contributor.author","Kruse, Eberhard"],["dc.contributor.author","Steiner, W."],["dc.date.accessioned","2018-11-07T10:56:55Z"],["dc.date.available","2018-11-07T10:56:55Z"],["dc.date.issued","2005"],["dc.description.abstract","Objectives: We performed a prospective study to assess respiratory function and voice quality before and after laser microsurgical bilateral posterior cordectonly performed for chronic airway obstruction in patients with bilateral vocal fold paralysis. Methods: In 17 patients a laser microsurgical posterior cordectomy was performed as an immediate bilateral approach. Roughness, breathiness, hoarseness, and dyspnea were evaluated both subjectively (on a scale from 0 to 3) and objectively (body plethysmography, computerized voice analysis: Gottingen Hoarseness Diagram). Results: After laser surgery, the patients ' respiratory function was significantly increased and was sufficient for all activities of daily living. The body plethysmographic measure of airway resistance had superior descriptive power and correlated significantly with the clinical degree of dyspnea (scale 0 to 3). Pretreatment and posttreatment impairment of voice quality was objectively documented with the Gottingen Hoarseness Diagram; the phonatory results measured with it correlated significantly with the subjective clinical evaluation of hoarseness. Aphonia did not occur. Conclusions: A bilateral approach for laser microsurgical posterior cordectomy combines excellent airway improvement and satisfactory voice preservation. In bilateral vocal fold paralysis, pretreatment and posttreatment clinical data should be evaluated by objective measures."],["dc.identifier.isi","000231228800004"],["dc.identifier.pmid","16190092"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50129"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Annals Publ Co"],["dc.publisher.place","St louis"],["dc.relation.conference","Annual Scientific Meeting of the German-Society-of-Phoniatrics and Pedaudiology"],["dc.relation.eventlocation","Tubingen, GERMANY"],["dc.relation.issn","0003-4894"],["dc.title","Laser microsurgical bilateral posterior cordectomy for the treatment of bilateral vocal fold paralysis"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","994"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY"],["dc.bibliographiccitation.lastpage","999"],["dc.bibliographiccitation.volume","129"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Mrugalla, S."],["dc.contributor.author","Laskawi, Rainer"],["dc.contributor.author","Frohlich, M."],["dc.contributor.author","Stuermer, Ingo W."],["dc.contributor.author","Kruse, Eberhard"],["dc.contributor.author","Ambrosch, Petra"],["dc.contributor.author","Steiner, W."],["dc.date.accessioned","2018-11-07T10:36:16Z"],["dc.date.available","2018-11-07T10:36:16Z"],["dc.date.issued","2003"],["dc.description.abstract","Objectives: To assess the merits of computer-aided voice analysis procedures for very irregular voices of patients after total and laser surgical partial laryngectomy, and to characterize, qualitative differences in speech and voice function between these 2 groups of patients. Design: Cross-sectional study. Setting: University hospital in Gottingen, Germany. Patients: Twenty-nine patients with advanced laryngeal carcinomas (T3-T4; according to the Union Internationale Contre le Cancer, TNM staging system, stages III-IVa) were examined: 18 patients with tracheoesophageal speech (voice prosthesis) after total laryngectomy and 11 patients who underwent partial transoral resection of the larynx (by means of laser microsurgery without surgical voice rehabilitation). Main Outcome Measures: Speech intelligibility was measured by a standardized and validated telephone test, and voice quality was determined by 2 computerized voice analysis systems (multidimensional voice program and Gottingen hoarseness diagram). Results: The telephone test demonstrated A significantly better speech performance of the patients who had undergone organ-preserving surgery. The voices of both patient groups were too irregular for a qualitative differentiation with the multidimensional voice program. The multidimensional voice program results also failed to show significant correlations to speech intelligibility. The Gottingen hoarseness diagram showed significantly more regular voices in patients with partial laryngectomy than total laryngectomy. These results were correlated with speech intelligibility. Conclusions: The Gottingen hoarseness diagram is suitable for a qualitative assessment even of irregular voices. Voice prosthesis offers a voice quality that at best approaches that of patients with partial laryngectomy."],["dc.identifier.doi","10.1001/archotol.129.9.994"],["dc.identifier.isi","000185220400015"],["dc.identifier.pmid","12975275"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45285"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Medical Assoc"],["dc.relation.issn","0886-4470"],["dc.title","Assessment of irregular voices after total and laser surgical partial laryngectomy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1092"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","HNO"],["dc.bibliographiccitation.lastpage","1096"],["dc.bibliographiccitation.volume","50"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Kruse, Eberhard"],["dc.date.accessioned","2018-11-07T09:45:00Z"],["dc.date.available","2018-11-07T09:45:00Z"],["dc.date.issued","2002"],["dc.identifier.doi","10.1007/s00106-002-0693-x"],["dc.identifier.isi","000179867600012"],["dc.identifier.pmid","12474134"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34517"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0017-6192"],["dc.title","Modern sociomedical views of dysphonia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","4"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Langenbeck s Archives of Surgery"],["dc.bibliographiccitation.lastpage","8"],["dc.bibliographiccitation.volume","391"],["dc.contributor.author","Kruse, Eberhard"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Schiel, R."],["dc.date.accessioned","2018-11-07T10:23:55Z"],["dc.date.available","2018-11-07T10:23:55Z"],["dc.date.issued","2006"],["dc.description.abstract","Background and aims: The purpose of this study was to present the current topographic and anatomical knowledge in neurolaryngology, with special regard to laryngeal paralyses as a major complication in thyroid surgery. Patients and methods: Microscopic anatomical preparation of 22 human hemilarynges was accomplished. Results: Due to their neuroanatomical courses, the following extralaryngeal nerves may be at risk in thyroid surgery: the external branch of the superior laryngeal nerve, the paralaryngeal part of the vagal nerve, the Ansa Galeni, the trunk of the recurrent laryngeal nerve (RLN) and the delicate branches of the RLN to the posterior cricoarytaenoid muscle. The anterior and posterior branches of the RLN (antRLN and postRLN) are less endangered by thyroid surgery because they are covered by the thyroid cartilage and posterior cricoarytaenoid muscle (PCA), respectively. In contrast, the antRLN is vulnerable if a ventilation tube is dislocated, with cuff-induced pressure to the glottic level. Conclusion: The increased knowledge in neurolaryngology provides the basis for a selective neuromonitoring to lower the risk of laryngeal paralyses after thyroid surgery."],["dc.identifier.doi","10.1007/s00423-005-0011-7"],["dc.identifier.isi","000235058500002"],["dc.identifier.pmid","16374605"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42557"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.conference","International Symposium on Modern Technologies in Thyroid Surgery"],["dc.relation.eventlocation","Halle, GERMANY"],["dc.relation.issn","1435-2443"],["dc.title","Functional anatomy of the recurrent and superior laryngeal nerve"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","594"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Annals of Otology Rhinology & Laryngology"],["dc.bibliographiccitation.lastpage","598"],["dc.bibliographiccitation.volume","116"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Laskawi, Rainer"],["dc.contributor.author","Kruse, Eberhard"],["dc.date.accessioned","2018-11-07T10:59:45Z"],["dc.date.available","2018-11-07T10:59:45Z"],["dc.date.issued","2007"],["dc.description.abstract","Objectives: We sought to treat autophonia due to a patulous eustachian tube using botulinum toxin. Methods: Because we assumed that the patulous eustachian tube was caused by abnormal activity of paratubal muscles (tensor and levator veli palatini muscles and salpingopharyngeus muscle), paralysis was performed via injection of botulinum toxin type A in a 45-year-old female professional musician who had had chronic unilateral autophonia for 20 years. In addition to a patient interview, an endoscopic examination of the nasopharynx (posterior rhinoscopy), ear microscopy, and impedance audiometry were performed to verify the diagnosis and the outcome after treatment. Results: The autophonia disappeared 1 week after treatment. Normalized tympanic ventilation was verified by impedance audiometry after 8 weeks. The period of symptom relief was 9 months. Conclusions: The administration of botulinum toxin type A provides a new option in the treatment of patulous eustachian tube. The reliability of this method and the effect of repeated injections remains to be proved in future studies."],["dc.identifier.isi","000248962300007"],["dc.identifier.pmid","17847727"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50773"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Annals Publ Co"],["dc.relation.issn","0003-4894"],["dc.title","Successful treatment of autophonia with botulinum toxin: Case report"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","923"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","European Archives of Oto-Rhino-Laryngology"],["dc.bibliographiccitation.lastpage","928"],["dc.bibliographiccitation.volume","272"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Steinle, Julia"],["dc.contributor.author","Asendorf, Thomas"],["dc.contributor.author","Kruse, Eberhard"],["dc.date.accessioned","2018-11-07T09:59:16Z"],["dc.date.available","2018-11-07T09:59:16Z"],["dc.date.issued","2015"],["dc.description.abstract","The objective of this study was to improve the evaluation of unilateral vocal fold paralyses (uVFP) by means of an area measurement of the glottic plane, which describes the position of the paralysed vocal fold. The area measurements were related to electromyographic findings and clinical outcome (recovery, voice quality). In 56 patients (33 women and 23 men), uVFP were confirmed by endolaryngeal electromyography (EMG) of the paralysed vocal fold and cricothyroid muscles (CT). The EMG response was classified on a 4-point scale (from 0 to 3). Vocal fold position was divided into 'paramedian' and 'intermediate' and additionally quantified by measurement of the glottic area. An 'area quotient' (AQ) was calculated and related to the EMG findings and clinical outcome. Voice qualities were objectified regarding their additive noise (breathiness) and irregularity (roughness) using the 'Gottingen Hoarseness Diagram'. The majority of uVFP was due to iatrogenic lesions. The AQ of classically graduated 'paramedian' and 'intermediate' vocal fold positions was significantly different but did not correlate with objective voice quality values. There were no significant correlations regarding EMG findings, duration or recovery from paralyses. Laryngeal EMG remains the gold standard for verifying uVFP. But EMG did not correlate significantly with AQ or functional outcome of uVFP. The measurement of an AQ is suitable for obtaining continuous data describing the position of paralysed vocal folds beyond the terms 'paramedian' or 'intermediate' and provides the basis for clinical evaluations of diagnostic tools and therapeutic interventions."],["dc.identifier.doi","10.1007/s00405-014-3442-3"],["dc.identifier.isi","000351517900021"],["dc.identifier.pmid","25519473"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37552"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1434-4726"],["dc.relation.issn","0937-4477"],["dc.title","Consideration of vocal fold position in unilateral vocal fold paralyses"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Strahlentherapie und Onkologie"],["dc.bibliographiccitation.volume","184"],["dc.contributor.author","Christiansen, H."],["dc.contributor.author","Ewen, Andreas"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Martin, A."],["dc.contributor.author","Vorwerk, Hilke"],["dc.contributor.author","Hermann, Robert Michael"],["dc.contributor.author","Hess, C. F."],["dc.contributor.author","Kruse, Eberhard"],["dc.contributor.author","Pradier, Olivier"],["dc.date.accessioned","2018-11-07T11:15:52Z"],["dc.date.available","2018-11-07T11:15:52Z"],["dc.date.issued","2008"],["dc.format.extent","70"],["dc.identifier.isi","000255034700181"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54460"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Urban & Vogel"],["dc.publisher.place","Munich"],["dc.relation.conference","14th Annual Congress of the Deutschen-Gesellschaft-fur-Radioonkologie/25th Annual Conference of the Osterreichischen-Gesellschaft-fur-Radioonkologie-Radiobiologie-und-Mediz inische-Radiophysik"],["dc.relation.eventlocation","Vienna, AUSTRIA"],["dc.relation.issn","0179-7158"],["dc.title","Objective and subjective functional limitation and oncological results according to organ based laser micro-surgical resection and adjuvant radiotherapy foe local advanced Larynx carcinoma"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]