Töpperwien, Mareike

[["dc.bibliographiccitation.firstpage","383"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","European Biophysics Journal"],["dc.bibliographiccitation.lastpage","392"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Töpperwien, M."],["dc.contributor.author","Priebe, M."],["dc.contributor.author","Salditt, T."],["dc.date.accessioned","2017-09-07T11:44:50Z"],["dc.date.available","2017-09-07T11:44:50Z"],["dc.date.issued","2016"],["dc.description.abstract","We have performed scanning nano-beam small-angle X-ray scattering (nano-SAXS) experiments on in vitro-formed actin filaments cross-linked with -actinin. The experimental method combines a high resolution in reciprocal space with a real space resolution as given by the spot-size of the nano-focused X-ray beam, and opens up new opportunities to study local super-molecular structures of actin filaments. In this first proof-of-concept, we show that the local orientation of actin bundles formed by the cross-linking can be visualized by the X-ray darkfield maps. The filament bundles give rise to highly anisotropic diffraction patterns showing distinct streaks perpendicular to the bundle axes. Interestingly, some diffraction patterns exhibit a fine structure in the form of intensity modulations allowing for a more detailed analysis of the order within the bundles. A first empirical quantification of these modulations is included in the present work."],["dc.identifier.doi","10.1007/s00249-015-1107-9"],["dc.identifier.gro","3141659"],["dc.identifier.isi","000378049100001"],["dc.identifier.pmid","26715112"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/6342"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: Deutsche Forschungsgemeinschaft [SFB 937/A11]"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.eissn","1432-1017"],["dc.relation.issn","0175-7571"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","x-ray scattering"],["dc.title","Actin bundles cross-linked with α -actinin studied by nanobeam X-ray diffraction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]