Feltgen, Nicolas

[["dc.bibliographiccitation.firstpage","1207"],["dc.bibliographiccitation.journal","Clinical Ophthalmology"],["dc.bibliographiccitation.lastpage","1213"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Storch, Marcus Werner"],["dc.contributor.author","Zinser, Greta"],["dc.contributor.author","Lauermann, Peer"],["dc.contributor.author","Khattab, Mohammed Haitham"],["dc.contributor.author","Nguyen-Höhl, Anna"],["dc.contributor.author","Raddatz, Dirk"],["dc.contributor.author","Gollisch, Katja"],["dc.contributor.author","Callizo, Josep"],["dc.contributor.author","Hoerauf, Hans"],["dc.contributor.author","Feltgen, Nicolas"],["dc.date.accessioned","2022-05-02T08:09:30Z"],["dc.date.available","2022-05-02T08:09:30Z"],["dc.date.issued","2022"],["dc.description.abstract","Purpose: To correlate functional and morphological parameters with foveal avascular zone’s (FAZ) size in diabetic patients with mild to moderate stage nonproliferative diabetic retinopathy. Methods: Monocentric and prospective study of a consecutive case series of diabetic patients. Medical history, best corrected visual acuity (BCVA), best corrected high/low contrast visual acuity (BChcVA/BClcVA), mean sensitivity (MS) and mean defect (MD) in central visual field testing, and FAZ size in fluorescein-angiography (FAG) were recorded. Macular thickness (central point thickness CPT, central subfield thickness CST) and volume measurements (central subfield volume CSV, total macular volume) were taken from SD-OCT (6x6mm ETDRS-grid). Groups were categorised as presenting FAZ sizes smaller (G1) or larger (G2) than 0.35mm2 . Smallest (Q1) and largest quartiles (Q3) were also compared. Results: Thirty-six of 40 patients were included. MS differed significantly between G1 (n = 6) and G2 (n = 30), and BChcVA/BClcVA as well as TMV correlated significantly with FAZ size in correlation analysis. Mean HbA1c tended to be lower in G1 than G2. Patients in G1 were slightly older than in G2. Treatment period with insulin was shorter in G1/Q1 than in G2/Q3. CPT and TMV were lower in G1/Q1 than in G2/Q3. Our analysis of the FAZ in terms of patient age, HbA1c, disease duration and insulin therapy duration revealed no significance. That lack of significance also applies to BCVA, MS, MD, CPT, CST and CSV. Conclusion: As significantly associated, contrast sensitivity, central visual field parameters and potentially retinal thickness or volume seem to be suitable to detect early macular ischaemia. However, we failed to establish any correlation between FAZ and BCVA"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.2147/OPTH.S358467"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107396"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-561"],["dc.relation.eissn","1177-5483"],["dc.rights","CC BY-NC 3.0"],["dc.title","Influence of the Size of the Foveal Avascular Zone on Functional and Morphological Parameters in Patients with Early-Stage Diabetic Retinopathy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Investigative Ophthalmology & Visual Science"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Striebe, Nina-Antonia"],["dc.contributor.author","Khattab, Mohammed"],["dc.contributor.author","van Oterendorp, Christian"],["dc.contributor.author","Callizo, Josep"],["dc.contributor.author","Hoerauf, Hans"],["dc.contributor.author","Feltgen, Nicolas"],["dc.date.accessioned","2018-11-07T10:08:44Z"],["dc.date.available","2018-11-07T10:08:44Z"],["dc.date.issued","2016"],["dc.identifier.isi","000394210601025"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39524"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Assoc Research Vision Ophthalmology Inc"],["dc.publisher.place","Rockville"],["dc.relation.conference","Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO)"],["dc.relation.eventlocation","Seattle, WA"],["dc.relation.issn","1552-5783"],["dc.relation.issn","0146-0404"],["dc.title","Is micropulse diode laser photocoagulation effective in treating recalcitrant chronic central serous chorioretinopathy?"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Der Ophthalmologe"],["dc.contributor.author","Feltgen, Nicolas"],["dc.contributor.author","Callizo, Josep"],["dc.contributor.author","Hattenbach, Lars-Olof"],["dc.contributor.author","Hoerauf, Hans"],["dc.date.accessioned","2021-06-01T10:49:09Z"],["dc.date.available","2021-06-01T10:49:09Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1007/s00347-021-01364-x"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86186"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1433-0423"],["dc.relation.issn","0941-293X"],["dc.title","The urgency of surgical treatment for rhegmatogenous retinal detachment"],["dc.title.translated","Dringlichkeit der operativen Versorgung bei der rissbedingten Netzhautablösung"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e933"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Acta Ophthalmologica"],["dc.bibliographiccitation.lastpage","e941"],["dc.bibliographiccitation.volume","96"],["dc.contributor.author","Feltgen, Nicolas"],["dc.contributor.author","Hattenbach, Lars-Olof"],["dc.contributor.author","Bertelmann, Thomas"],["dc.contributor.author","Callizo, Josep"],["dc.contributor.author","Rehak, Matus"],["dc.contributor.author","Wolf, Armin"],["dc.contributor.author","Berk, Hüsnü"],["dc.contributor.author","Eter, Nicole"],["dc.contributor.author","Lang, Gabriele E."],["dc.contributor.author","Pielen, Amelie"],["dc.contributor.author","Schmitz-Valckenberg, Steffen"],["dc.contributor.author","Quiering, Claudia"],["dc.contributor.author","Rose, Uwe"],["dc.contributor.author","Hoerauf, Hans"],["dc.date.accessioned","2020-12-10T18:26:52Z"],["dc.date.available","2020-12-10T18:26:52Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1111/aos.13770"],["dc.identifier.issn","1755-375X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76197"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Comparison of ranibizumab versus dexamethasone for macular oedema following retinal vein occlusion: 1-year results of the COMRADE extension study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","aos.14940"],["dc.bibliographiccitation.firstpage","295"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Acta Ophthalmologica"],["dc.bibliographiccitation.lastpage","301"],["dc.bibliographiccitation.volume","100"],["dc.contributor.affiliation","Gebler, Marie; 1\r\nDepartment of Ophthalmology University Medical Center Goettingen Goettingen Germany"],["dc.contributor.affiliation","Pfeiffer, Sebastian; 2\r\nDepartment of Research, Teaching and Clinical Science University Medical Center Goettingen Goettingen Germany"],["dc.contributor.affiliation","Callizo, Josep; 1\r\nDepartment of Ophthalmology University Medical Center Goettingen Goettingen Germany"],["dc.contributor.affiliation","Hoerauf, Hans; 1\r\nDepartment of Ophthalmology University Medical Center Goettingen Goettingen Germany"],["dc.contributor.affiliation","Feltgen, Nicolas; 1\r\nDepartment of Ophthalmology University Medical Center Goettingen Goettingen Germany"],["dc.contributor.author","Gebler, Marie"],["dc.contributor.author","Pfeiffer, Sebastian"],["dc.contributor.author","Callizo, Josep"],["dc.contributor.author","Hoerauf, Hans"],["dc.contributor.author","Feltgen, Nicolas"],["dc.contributor.author","Bemme, Sebastian"],["dc.date.accessioned","2021-07-05T14:57:41Z"],["dc.date.available","2021-07-05T14:57:41Z"],["dc.date.issued","2021"],["dc.date.updated","2022-06-14T21:23:28Z"],["dc.description.abstract","Abstract Purpose To assess the incidence of cystoid macular oedema (CME) diagnosed by spectral domain optical coherence tomography (SD‐OCT) after primary rhegmatogenous retinal detachment (RRD) surgery. Methods From April 2016 to October 2017, 150 eyes of 150 patients presenting with primary RRD were included consecutively in this prospective single‐centre study. Patients with the following characteristics were excluded: previous vitreoretinal surgery, combined cataract surgery, preoperatively presentation with any intraocular or systemic inflammatory condition, visible macular oedema or epiretinal membrane (ERM) on funduscopy. SD‐OCT (Spectralis, Heidelberg Engineering) was conducted 3 and 6 weeks after surgery. Results One hundred and twenty‐eight of the 150 patients completed the study, of whom 107 (age: 61.7 ± 11.5 years, mean ± SD) showed successful retinal attachment during follow‐up visits. The most frequent operation method was scleral buckling (54.2%), followed by vitrectomy (25.2%) and the combination of both techniques (20.6%). Postoperative SD‐OCT revealed CME, neurosensory detachment and ERM in 18.7, 31.8 and 32.7% of all cases, respectively. The risk of postoperative CME was significantly elevated in patients with ERM (42.9 versus 6.9%, p < 0.001). In addition, patients with initial detachment of the macula had more postoperative CME (26.5 versus 11.1%, p = 0.044). BCVA improvement was significantly lower in patients with CME compared to patients without 6 weeks after surgery for macula‐on RRD. Conclusions This prospective study confirmed that postoperative CME is a frequent complication after RRD surgery; we identified ERM and macula‐off RRD as potential risk factors. As CME potentially delays visual recovery, postoperative follow‐ups should include SD‐OCT."],["dc.identifier.doi","10.1111/aos.14940"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/87706"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-441"],["dc.relation.eissn","1755-3768"],["dc.relation.issn","1755-375X"],["dc.rights","This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made."],["dc.title","Incidence and risk factors for macular oedema after primary rhegmatogenous retinal detachment surgery: a prospective single‐centre study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Der Ophthalmologe"],["dc.contributor.author","Take, Patricia"],["dc.contributor.author","Dittmann, Carolin Alisa"],["dc.contributor.author","Mackerodt, Laura"],["dc.contributor.author","Callizo, Josep"],["dc.contributor.author","Striebe, Nina-Antonia"],["dc.contributor.author","Hoerauf, Hans"],["dc.contributor.author","Feltgen, Nicolas"],["dc.contributor.author","Bemme, Sebastian"],["dc.date.accessioned","2021-04-14T08:23:36Z"],["dc.date.available","2021-04-14T08:23:36Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00347-020-01218-y"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80983"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1433-0423"],["dc.relation.issn","0941-293X"],["dc.title","Das modifizierte Treat-and-Extend-Schema mit Injektionsblöcken in der IVOM-Therapie"],["dc.title.alternative","Retrospektive Analyse aus der täglichen klinischen Anwendung"],["dc.title.translated","The modified treat and extend scheme with injection blocks in intravitreal injection treatment: Retrospective analysis from the routine clinical application"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e78538"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Pielen, Amelie"],["dc.contributor.author","Feltgen, Nicolas"],["dc.contributor.author","Isserstedt, Christin"],["dc.contributor.author","Callizo, Josep"],["dc.contributor.author","Junker, Bernd"],["dc.contributor.author","Schmucker, Christine"],["dc.date.accessioned","2018-11-07T09:18:29Z"],["dc.date.available","2018-11-07T09:18:29Z"],["dc.date.issued","2013"],["dc.description.abstract","Background: Intravitreal agents have replaced observation in macular edema in central (CRVO) and grid laser photocoagulation in branch retinal vein occlusion (BRVO). We conducted a systematic review to evaluate efficacy and safety outcomes of intravitreal therapies for macular edema in CRVO and BRVO. Methods: And Findings: MEDLINE, Embase, and the Cochrane Library were systematically searched for RCTs with no limitations of language and year of publication. 11 RCTs investigating anti-VEGF agents (ranibizumab, bevacizumab, aflibercept) and steroids (triamcinolone, dexamethasone implant) with a minimum follow-up of 1 year were evaluated. Efficacy: CRVO: Greatest gain in visual acuity after 12 months was observed both under aflibercept 2 mg: +16.2 letters (8.5 injections), and under bevacizumab 1.25 mg: +16.1 letters (8 injections). Ranibizumab 0.5 mg improved vision by +13.9 letters (8.8 injections). Triamcinolone 1 mg and 4 mg stabilized visual acuity at a lower injection frequency (-1.2 letters, 2 injections). BRVO: Ranibizumab 0.5 mg resulted in a visual acuity gain of +18.3 letters (8.4 injections). The effect of dexamethasone implant was transient after 1.9 implants in both indications. Safety: Serious ocular adverse events were rare, e. g., endophthalmitis occurred in 0.0-0.9%. Major differences were found in an indirect comparison between steroids and anti-VEGF agents for cataract progression (19.8-35.0% vs. 0.9-7.0%) and in required treatment of increased intraocular pressure (7.0-41.0% vs. none). No major differences were identified in systemic adverse events. Conclusions: Anti-VEGF agents result in a promising gain of visual acuity, but require a high injection frequency. Dexamethasone implant might be an alternative, but comparison is impaired as the effect is temporary and it has not yet been tested in PRN regimen. The ocular risk profile seems to be favorable for anti-VEGF agents in comparison to steroids. Because comparative data from head-to-head trials are missing currently, clinicians and patients should carefully weigh the benefit-harm ratio."],["dc.identifier.doi","10.1371/journal.pone.0078538"],["dc.identifier.isi","000326155400083"],["dc.identifier.pmid","24205253"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10754"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28422"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","Efficacy and Safety of Intravitreal Therapy in Macular Edema Due to Branch and Central Retinal Vein Occlusion: a Systematic Review"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","850"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Der Ophthalmologe"],["dc.bibliographiccitation.lastpage","856"],["dc.bibliographiccitation.volume","116"],["dc.contributor.author","Striebe, N.-A."],["dc.contributor.author","Feltgen, N."],["dc.contributor.author","Khattab, M. H."],["dc.contributor.author","Spier, L."],["dc.contributor.author","Callizo, J."],["dc.contributor.author","Bemme, S."],["dc.contributor.author","Hoerauf, H."],["dc.contributor.author","van Oterendorp, C."],["dc.date.accessioned","2020-12-10T14:10:17Z"],["dc.date.available","2020-12-10T14:10:17Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1007/s00347-018-0839-1"],["dc.identifier.eissn","1433-0423"],["dc.identifier.issn","0941-293X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70710"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Hat der Mikropulslaser bei chronischer CCS einen Effekt?"],["dc.title.alternative","Does the micropulse laser have an effect on chronic CSC?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2167"],["dc.bibliographiccitation.journal","Clinical Ophthalmology"],["dc.bibliographiccitation.lastpage","2179"],["dc.bibliographiccitation.volume","Volume 13"],["dc.contributor.author","Callizo, Josep"],["dc.contributor.author","Ziemssen, Focke"],["dc.contributor.author","Bertelmann, Thomas"],["dc.contributor.author","Feltgen, Nicolas"],["dc.contributor.author","Voegeler, Jessica"],["dc.contributor.author","Koch, Mirja"],["dc.contributor.author","Eter, Nicole"],["dc.contributor.author","Liakopoulos, Sandra"],["dc.contributor.author","Schmitz-Valckenberg, Steffen"],["dc.contributor.author","Spital, Georg"],["dc.date.accessioned","2020-12-10T18:43:01Z"],["dc.date.available","2020-12-10T18:43:01Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.2147/OPTH.S209253"],["dc.identifier.eissn","1177-5483"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78165"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation.eissn","1177-5483"],["dc.title","Real-World Data: Ranibizumab Treatment For Retinal Vein Occlusion In The OCEAN Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","858"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Der Ophthalmologe"],["dc.bibliographiccitation.lastpage","865"],["dc.bibliographiccitation.volume","117"],["dc.contributor.author","Feltgen, Nicolas"],["dc.contributor.author","Callizo, Josep"],["dc.contributor.author","Hattenbach, Lars-Olof"],["dc.contributor.author","Hoerauf, Hans"],["dc.date.accessioned","2021-04-14T08:24:48Z"],["dc.date.available","2021-04-14T08:24:48Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00347-020-01191-6"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81427"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1433-0423"],["dc.relation.issn","0941-293X"],["dc.title","Dringlichkeit der operativen Versorgung bei der rissbedingten Netzhautablösung"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]