Freimann, Florian Baptist

[["dc.bibliographiccitation.firstpage","e74"],["dc.bibliographiccitation.journal","World Neurosurgery"],["dc.bibliographiccitation.lastpage","e80"],["dc.bibliographiccitation.volume","131"],["dc.contributor.author","Müller, Sebastian J."],["dc.contributor.author","Freimann, Florian B."],["dc.contributor.author","von der Brelie, Christian"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Schatlo, Bawarjan"],["dc.date.accessioned","2020-12-10T15:21:43Z"],["dc.date.available","2020-12-10T15:21:43Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.wneu.2019.07.014"],["dc.identifier.issn","1878-8750"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73130"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Test-Retest Reliability of Outpatient Telemetric Intracranial Pressure Measurements in Shunt-Dependent Patients with Hydrocephalus and Idiopathic Intracranial Hypertension"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","655"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Neurosurgical Review"],["dc.bibliographiccitation.lastpage","661"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Moringlane, R. B."],["dc.contributor.author","Keric, N."],["dc.contributor.author","Freimann, F. B."],["dc.contributor.author","Mielke, D."],["dc.contributor.author","Burger, R."],["dc.contributor.author","Duncker, D."],["dc.contributor.author","Rohde, V."],["dc.contributor.author","Eckardstein, K. L. V."],["dc.date.accessioned","2018-10-09T07:22:45Z"],["dc.date.available","2018-10-09T07:22:45Z"],["dc.date.issued","2017"],["dc.description.abstract","Decompressive hemicraniectomy (DH) plus duroplasty was demonstrated to be effective for treating critically elevated intracranial pressure (ICP). In order to shorten operation time and to avoid the use of autologous or heterologous material, durotomy has been introduced as an alternative to duroplasty. Only limited data is available on the effect of DH and durotomy on the increased ICP in traumatic brain injury (TBI). Therefore, we collected consecutive intraoperative ICP readings during the different steps of DH and durotomy in TBI patients. Eighteen patients with TBI and uncontrollable ICP increase (measured by either an intraparenchymal or an intraventricular ICP probe) underwent DH and durotomy. ICP readings as well as mean arterial blood pressure (MAP) and arterial PCO2 were obtained during defined stages of the operation. Surgical complications of the durotomy itself and of cranioplasty after 3 months were recorded. The outcome was assessed prior to cranioplasty using the Glasgow Outcome Scale (GOS). ICP dropped significantly during surgery from a mean of 41 ( ± 16.2) mmHg at the beginning to a mean of 11.8 ( ± 7.5) mmHg at the end (p ≤ 0.001). A first significant ICP-decrease to a mean of 18 ( ± 10.8) mmHg (p ≤ 0.001) was detected after removal of the bone flap, and a second significant ICP-decrease to a mean of 10.6 ( ± 5.3) mmHg (p < 0.001) during durotomy. The mean operation time was 115.3 min ( ± 49.6). Five patients (28%) died; seven patients (39%) had a good outcome (GOS 5). There were no relevant complications associated to durotomy. Durotomy after DH is a safe and straightforward procedure, which significantly lowers critically increased ICP in patients with TBI. Although no graft is used, dural preparation for cranioplasty at 3 months is easily possible."],["dc.fs.pkfprnr","86428"],["dc.identifier.doi","10.1007/s10143-017-0823-2"],["dc.identifier.fs","633512"],["dc.identifier.pmid","28185018"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15893"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1437-2320"],["dc.title","Efficacy and safety of durotomy after decompressive hemicraniectomy in traumatic brain injury"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Neurological Surgery Part A Central European Neurosurgery"],["dc.bibliographiccitation.volume","77"],["dc.contributor.author","Freimann, Florian Baptist"],["dc.contributor.author","Thomale, Ulrich-Wilhelm"],["dc.date.accessioned","2018-11-07T10:21:20Z"],["dc.date.available","2018-11-07T10:21:20Z"],["dc.date.issued","2016"],["dc.format.extent","1"],["dc.identifier.doi","10.1055/s-0035-1566300"],["dc.identifier.isi","000368522900001"],["dc.identifier.pmid","26761508"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42063"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Thieme Medical Publ Inc"],["dc.relation.issn","2193-6323"],["dc.relation.issn","2193-6315"],["dc.title","Obituary Christian Sprung In Memoriam"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1273"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","1278"],["dc.bibliographiccitation.volume","158"],["dc.contributor.author","Diesner, Naima"],["dc.contributor.author","Freimann, Florian"],["dc.contributor.author","Clajus, Christin"],["dc.contributor.author","Kallenberg, Kai"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Stockhammer, Florian"],["dc.date.accessioned","2018-11-07T10:12:27Z"],["dc.date.available","2018-11-07T10:12:27Z"],["dc.date.issued","2016"],["dc.description.abstract","Gravitational valves (GVs) prevent overdrainage in ventriculoperitoneal shunting (VPS). However, there are no data available on the appropriate opening pressure in the shunt system when implementing a GV. We performed a retrospective analysis of hydrocephalic patients who were successfully treated with VPS which included one or more GV. In this retrospective study in adult VPS patients with GVs, we analysed all available data, including the most recent computed tomography (CT) scans, to determine the best adjustments for alleviating any symptoms of overdrainage and underdrainage. Vertical effective opening pressure (VEOP) of the entire shunt system, including the differential pressure valve, was determined. One hundred and twenty-two patients were eligible for the study. Of these, female patients revealed a higher VEOP compared with males (mean, 35.6 cmH(2)O [SD +/- 2.46] vs 28.9 cmH(2)O [SD +/- 0.87], respectively, p = 0.0072, t-test). In patients older than 60 years, lower VEOPs, by a mean of 6.76 cmH(2)O +/- 2.37 (p = 0.0051), were necessary. Mean VEOP was found to be high in idiopathic intracranial hypertension (IIH; 41.6 cmH(2)O) and malresorptive and congenital HC (35.9 and 36.3), but low in normal pressure HC (27.5, p = 0.0229; one-way ANOVA). In the total cohort, body mass index (BMI) and height did not correlate with VEOP. Twelve patients required a VEOP of more than 40 cmH(2)O, and in eight of these patients this was accomplished by using multiple GVs. All but one of these eight patients were of female gender, and none of the latter were treated for normal pressure hydrocephalus (NPH) (p = 0.0044 and p = 0.0032, Fisher's exact test). In adult VPS patients, female gender increases the risk of overdrainage requiring higher VEOPs. Initial implantation of adjustable GV should be considered in female patients treated with VP shunts for pathology other than NPH."],["dc.identifier.doi","10.1007/s00701-016-2827-z"],["dc.identifier.isi","000377719800007"],["dc.identifier.pmid","27177735"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40239"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.conference","Hydrocephalus Forum"],["dc.relation.eventlocation","Hannover, GERMANY"],["dc.relation.issn","0942-0940"],["dc.relation.issn","0001-6268"],["dc.title","Female gender predisposes for cerebrospinal fluid overdrainage in ventriculoperitoneal shunting"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2421"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","2430"],["dc.bibliographiccitation.volume","162"],["dc.contributor.author","Fiss, I."],["dc.contributor.author","Röhrig, P."],["dc.contributor.author","Hore, N."],["dc.contributor.author","von der Brelie, C."],["dc.contributor.author","Bettag, C."],["dc.contributor.author","Freimann, F. B."],["dc.contributor.author","Thomale, U.-W."],["dc.contributor.author","Rohde, V."],["dc.contributor.author","Brandner, S."],["dc.date.accessioned","2021-04-14T08:24:43Z"],["dc.date.available","2021-04-14T08:24:43Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00701-020-04519-y"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81400"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","0942-0940"],["dc.relation.issn","0001-6268"],["dc.title","In vitro performance of six combinations of adjustable differential pressure valves and fixed anti-siphon devices with and without vertical motion"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2191"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","2199"],["dc.bibliographiccitation.volume","156"],["dc.contributor.author","Freimann, Florian Baptist"],["dc.contributor.author","Kimura, Takaoki"],["dc.contributor.author","Stockhammer, Florian"],["dc.contributor.author","Schulz, Matthias"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Thomale, Ulrich-Wilhelm"],["dc.date.accessioned","2018-11-07T09:33:12Z"],["dc.date.available","2018-11-07T09:33:12Z"],["dc.date.issued","2014"],["dc.description.abstract","Anti-siphon devices (ASDs) of various working principles were developed to overcome overdrainage-related complications associated with ventriculoperitoneal shunting. We aimed to provide comparative data on the pressure and flow characteristics of six different types of ASDs (gravity-assisted, membrane-controlled, and flow-regulated) in order to achieve a better understanding of these devices and their potential clinical application. We analyzed three gravity-dependent ASDs (ShuntAssistant [SA], Miethke; Gravity Compensating Accessory [GCA], Integra; SiphonX [SX], Sophysa), two membrane-controlled ASDs (Anti-Siphon Device [IASD], Integra; Delta Chamber [DC], Medtronic), and one flow-regulated ASD (SiphonGuard [SG], Codman). Defined pressure conditions within a simulated shunt system were generated (differential pressure 10-80 cmH(2)O), and the specific flow and pressure characteristics were measured. In addition, the gravity-dependent ASDs were measured in defined spatial positions (0-90A degrees). The flow characteristics of the three gravity-assisted ASDs were largely dependent upon differential pressure and on their spatial position. All three devices were able to reduce the siphoning effect, but each to a different extent (flow at inflow pressure: 10 cmH(2)O, siphoning -20 cmH(2)O at 0A degrees/90A degrees: SA, 7.1 A +/- 1.2 /2.3 A +/- 0.5 ml/min; GCA, 10.5 A +/- 0.8/3.4 A +/- 0.4 ml/min; SX, 9.5 A +/- 1.2 /4.7 A +/- 1.9 ml/min, compared to control, 11.1 A +/- 0.4 ml/min [ p < 0.05]). The flow characteristics of the remaining ASDs were primarily dependent upon the inflow pressure effect (flow at 10 cmH2O, siphoning 0 cmH(2)O/ siphoning -20cmH(2)O: DC, 2.6 A +/- 0.1/ 4 A +/- 0.3 ml/min; IASD, 2.5 A +/- 0.2/ 0.8 A +/- 0.4 ml/min; SG, 0.8 A +/- 0.2 / 0.2 A +/- 0.1 ml/min [ p < 0.05 vs. control, respectively]). The tested ASDs were able to control the siphoning effect within a simulated shunt system to differing degrees. Future comparative trials are needed to determine the type of device that is superior for clinical application."],["dc.identifier.doi","10.1007/s00701-014-2201-y"],["dc.identifier.isi","000343884400023"],["dc.identifier.pmid","25123252"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31916"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","0942-0940"],["dc.relation.issn","0001-6268"],["dc.title","In vitro performance and principles of anti-siphoning devices"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1033"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","1040"],["dc.bibliographiccitation.volume","162"],["dc.contributor.author","Fiss, I."],["dc.contributor.author","Vanderheyden, M."],["dc.contributor.author","von der Brelie, C."],["dc.contributor.author","Bettag, C."],["dc.contributor.author","Hore, N."],["dc.contributor.author","Freimann, F."],["dc.contributor.author","Thomale, U.-W."],["dc.contributor.author","Rohde, V."],["dc.contributor.author","Brandner, S."],["dc.date.accessioned","2020-12-10T14:10:54Z"],["dc.date.available","2020-12-10T14:10:54Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00701-020-04228-6"],["dc.identifier.eissn","0942-0940"],["dc.identifier.issn","0001-6268"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70915"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","In vitro performance of combinations of anti-siphon devices with differential pressure valves in relation to the spatial position"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","519"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","524"],["dc.bibliographiccitation.volume","160"],["dc.contributor.author","Böse, Brit"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Fiss, Ingo"],["dc.contributor.author","Freimann, Florian Baptist"],["dc.date.accessioned","2020-12-10T14:10:52Z"],["dc.date.available","2020-12-10T14:10:52Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00701-017-3439-y"],["dc.identifier.eissn","0942-0940"],["dc.identifier.issn","0001-6268"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70903"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","A counterforce to diversion of cerebrospinal fluid during ventriculoperitoneal shunting: the intraperitoneal pressure. An observational study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1351"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","1356"],["dc.bibliographiccitation.volume","156"],["dc.contributor.author","Freimann, Florian Baptist"],["dc.contributor.author","Luhdo, Marie-Luise"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Vajkoczy, Peter"],["dc.contributor.author","Wolf, Stefan"],["dc.contributor.author","Sprung, Christian"],["dc.date.accessioned","2018-11-07T09:38:15Z"],["dc.date.available","2018-11-07T09:38:15Z"],["dc.date.issued","2014"],["dc.description.abstract","The in-line combination of adjustable differential pressure valves with fixed gravitational units is increasingly recommended in the literature. The spatial positioning of the gravitational unit is thereby decisive for the valve opening pressure. We aimed at providing data on factors contributing to primary overdrainage and underdrainage of cerebrospinal fluid (CSF), with special attention paid to the implantation angle of the gravitational unit. Weretrospectively analyzed the postoperative course of 376 consecutive patients who received a ventriculoperitoneal shunt with a proGAV valve. The incidence of both primary CSF overdrainage and underdrainage was correlated with the implantation angle of the gravitational unit in regard to the Frankfurt horizontal plane and the patients' general parameters. Primary overdrainage was found in 41 (10.9 %) patients. Primary underdrainage was found in 113 (30.1 %) patients. A mean deviation of 10A degrees (+/- 7.8) for the gravitational unit in regard to the vertical line to the Frankfurt horizontal plane was found. In 95 % of the cases the deviation was less than 25A degrees. No significant correlation between the implantation angle and the incidence of overdrainage or underdrainage of CSF was found. The patients' age and having single hydrocephalus entities were identified as factors significantly predisposing patients to overdrainage or underdrainage. The implantation of the gravitational unit of the proGAV valve within a range of at least 10A degrees in regard to the vertical line to the Frankfurt horizontal plane does not seem to predispose patients to primary overdrainage or underdrainage in ventriculoperitoneal shunting. The plane may serve as a useful reference for the surgeon's orientation."],["dc.identifier.doi","10.1007/s00701-014-2076-y"],["dc.identifier.isi","000338195300015"],["dc.identifier.pmid","24792967"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33032"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","0942-0940"],["dc.relation.issn","0001-6268"],["dc.title","The Frankfurt horizontal plane as a reference for the implantation of gravitational units: a series of 376 adult patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Neurosurgical Review"],["dc.contributor.author","Bettag, Christoph"],["dc.contributor.author","von der Brelie, Christian"],["dc.contributor.author","Freimann, Florian Baptist"],["dc.contributor.author","Thomale, Ulrich-Wilhelm"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Fiss, Ingo"],["dc.date.accessioned","2021-06-01T10:49:17Z"],["dc.date.available","2021-06-01T10:49:17Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract Diagnosis of symptomatic valve malfunction in hydrocephalic patients treated with VP-Shunt (VPS) might be difficult. Clinical symptoms such as headache or nausea are nonspecific, hence cerebrospinal fluid (CSF) over- or underdrainage can only be suspected but not proven. Knowledge concerning valve malfunction is still limited. We aim to provide data on the flow characteristics of explanted shunt valves in patients with suspected valve malfunction. An in vitro shunt laboratory setup was used to analyze the explanted valves under conditions similar to those in an implanted VPS. The differential pressure (DP) of the valve was adjusted stepwise to 20, 10, 6, and 4 cmH 2 O. The flow rate of the explanted and the regular flow rate of an identical reference valve were evaluated at the respective DPs. Twelve valves of different types (Codman CertasPlus valve n  = 3, Miethke Shuntassistant valve n  = 4, Codman Hakim programmable valve n  = 3, DP component of Miethke proGAV 2.0 valve n  = 2) from eight hydrocephalic patients (four male), in whom valve malfunction was assumed between 2016 and 2017, were replaced with a new valve. Four patients suffered from idiopathic normal pressure (iNPH), three patients from malresorptive and one patient from obstructive hydrocephalus. Post-hoc analysis revealed a significant difference ( p  < 0.001) of the flow rate between each explanted valve and their corresponding reference valve, at each DP. In all patients, significant alterations of flow rates were demonstrated, verifying a valve malfunction, which could not be objectified by the diagnostic tools used in the clinical routine. In cases with obscure clinical VPS insufficiency, valve deficiency should be considered."],["dc.identifier.doi","10.1007/s10143-021-01564-8"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86232"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1437-2320"],["dc.relation.issn","0344-5607"],["dc.title","In vitro testing of explanted shunt valves in hydrocephalic patients with suspected valve malfunction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]