Salditt, Tim

[["dc.bibliographiccitation.artnumber","061908"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Physical Review E"],["dc.bibliographiccitation.volume","71"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.contributor.author","Seydel, Tilo"],["dc.contributor.author","Demmel, F."],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:54:26Z"],["dc.date.available","2017-09-07T11:54:26Z"],["dc.date.issued","2005"],["dc.description.abstract","We report a high energy-resolution neutron backscattering study to investigate slow motions on nanosecond time scales in highly oriented solid supported phospholipid bilayers of the model system DMPC-d54 (deuterated 1,2-dimyristoyl-sn-glycero-3-phoshatidylcholine), hydrated with heavy water. This technique allows to discriminate the onset of mobility at different length scales for the different molecular components, as, e. g., the lipid acyl-chains and the hydration water in between the membrane stacks, respectively, and provides a benchmark test regarding the feasibility of neutron backscattering investigations on these sample systems. We discuss freezing of the lipid acyl-chains, as observed by this technique, and observe a second freezing transition which we attribute to the hydration water."],["dc.identifier.doi","10.1103/PhysRevE.71.061908"],["dc.identifier.gro","3143841"],["dc.identifier.isi","000230274500058"],["dc.identifier.pmid","16089766"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1399"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1539-3755"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","membrane biophysics"],["dc.title","Molecular motions in lipid bilayers studied by the neutron backscattering technique"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1191"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.lastpage","1196"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.contributor.author","Seydel, Tilo"],["dc.contributor.author","Haeussler, Wolfgang"],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:52:40Z"],["dc.date.available","2017-09-07T11:52:40Z"],["dc.date.issued","2006"],["dc.description.abstract","While most spectroscopic techniques, as e.g., nuclear magnetic resonance or dielectric spectroscopy, probe macroscopic responses, neutron and within some restrictions also x-ray scattering experiments give the unique access to microscopic dynamics at length scales of intermolecular or atomic distances. Only recently, it has become possible to study collective dynamics of planar lipid bilayers using neutron spectroscopy techniques [M. Rheinstadter, C. Ollinger, G. Fragneto, E Demmel, and T. Salditt, Phys. Rev. Lett. 93, 108107 (2004)]. We determined the dispersion relation of the coherent fast picosecond density fluctuations on nearest-neighbor distances of the phospholipid acyl chains in the gel and in the fluid phases of a dimyristoylphoshatidylcholine bilayer. The experiments shed light on the evolution of structure and dynamics, and the relation between them, in the range of the gel-fluid main phase transition. The scattering volume restriction for inelastic neutron experiments was overcome by stacking several thousands of highly aligned membrane bilayers. By combining different neutron-scattering techniques, namely, three-axis, backscattering, and spin-echo spectroscopies, we present measurements of short- and long-wavelength collective fluctuations in biomimetic and biological membranes in a large range in momentum and energy transfer, covering time scales from about 0.1 ps to almost 1 mu s and length scales from 3 angstrom to about 0.1 mu m. The neutron-backscattering technique gives information about slow molecular dynamics of lipid acyl chains and the \"membrane-water,\" i.e., the water molecules in between the stacked bilayers in the nanosecond time range [M. C. Rheinstadter, T. Seydel, F. Demmel, and T. Salditt, Phys. Rev. E 71, 061908 (2005)]. The dispersion relations of the long-wavelength undulation modes in lipid bilayers with nanosecond relaxation times can be determined by quasielastic reflectometry on spin-echo spectrometers and give direct access to the elasticity parameters of the membranes. (c) 2006 American Vacuum Society."],["dc.identifier.doi","10.1116/1.2167979"],["dc.identifier.gro","3143667"],["dc.identifier.isi","000239048100052"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1206"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","A V S Amer Inst Physics"],["dc.publisher.place","Melville"],["dc.relation.eventlocation","Boston, MA"],["dc.relation.ispartof","Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films"],["dc.relation.issn","0734-2101"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","membrane biophysics"],["dc.title","Exploring the collective dynamics of lipid membranes with inelastic neutron scattering"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","257"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Neutron Research"],["dc.bibliographiccitation.lastpage","268"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.contributor.author","Seydel, Tilo"],["dc.contributor.author","Farago, Bela"],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:54:11Z"],["dc.date.available","2017-09-07T11:54:11Z"],["dc.date.issued","2006"],["dc.identifier.doi","10.1080/10238160600975424"],["dc.identifier.gro","3145125"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/2827"],["dc.notes.intern","Crossref Import"],["dc.notes.status","public"],["dc.relation.issn","1023-8166"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","x-ray scattering"],["dc.subject.gro","membrane biophysics"],["dc.title","Probing dynamics at interfaces: options for neutron and X-ray spectroscopy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","503"],["dc.bibliographiccitation.lastpage","530"],["dc.contributor.author","Salditt, Tim"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.date.accessioned","2017-09-07T11:54:12Z"],["dc.date.available","2017-09-07T11:54:12Z"],["dc.date.issued","2006"],["dc.identifier.doi","10.1007/3-540-29111-3_22"],["dc.identifier.gro","3145124"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/2826"],["dc.language.iso","en"],["dc.notes.intern","Crossref Import"],["dc.notes.status","final"],["dc.publisher","Springer"],["dc.publisher.place","Berlin"],["dc.relation.doi","10.1007/3-540-29111-3"],["dc.relation.eisbn","978-3-540-29111-4"],["dc.relation.isbn","3-540-29108-3"],["dc.relation.isbn","978-3-540-29108-4"],["dc.relation.ispartof","Neutron scattering in biology"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","membrane biophysics"],["dc.title","Structure and Dynamics of Model Membrane Systems Probed by Elastic and Inelastic Neutron Scattering"],["dc.type","book_chapter"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","108107"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Physical Review Letters"],["dc.bibliographiccitation.volume","93"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.contributor.author","Ollinger, C."],["dc.contributor.author","Fragneto, G"],["dc.contributor.author","Demmel, F."],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:43:18Z"],["dc.date.available","2017-09-07T11:43:18Z"],["dc.date.issued","2004"],["dc.description.abstract","We have studied the collective short wavelength dynamics in deuterated 1,2-dimyristoyl-sn-glycero-3-phoshatidylcholine (DMPC) bilayers by inelastic neutron scattering. The corresponding dispersion relation (h) over bar omega(Q) is presented for the gel and the fluid phase of this model system. The temperature dependence of the inelastic excitations indicates a phase coexistence between the two phases over a broad range and leads to a different assignment of excitations from that reported in a preceding inelastic x-ray scattering study [Phys. Rev. Lett. 86, 740 (2001)]. As a consequence, we find that the minimum in the dispersion relation is actually deeper in the gel than in the fluid phase. Finally, we can clearly identify an additional nondispersive (optical) mode predicted by molecular dynamics simulations [Phys. Rev. Lett. 87, 238101 (2001)]."],["dc.identifier.doi","10.1103/PhysRevLett.93.108107"],["dc.identifier.gro","3143947"],["dc.identifier.isi","000223717600072"],["dc.identifier.pmid","15447459"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1517"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","0031-9007"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","membrane biophysics"],["dc.title","Collective dynamics of lipid membranes studied by inelastic neutron scattering"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","136"],["dc.bibliographiccitation.issue","1-3"],["dc.bibliographiccitation.lastpage","139"],["dc.bibliographiccitation.volume","350"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.contributor.author","Ollinger, C."],["dc.contributor.author","Fragneto, G"],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:43:19Z"],["dc.date.available","2017-09-07T11:43:19Z"],["dc.date.issued","2004"],["dc.description.abstract","We present the first inelastic neutron scattering study of the short wavelength dynamics in a phospholipid bilayer. We show that inelastic neutron scattering using a triple-axis spectrometer at the high-flux reactor of the ILL yields the necessary resolution and signal to determine the dynamics of model membranes. The results can quantitatively be compared to recent Molecular Dynamics simulations. Reflectivity, in-plane correlations and the corresponding dynamics can be measured simultaneously to gain a maximum amount of information. With this technique, complete dispersion relations can be measured with a high-energy resolution. Structure and dynamics in phospholipid bilayers, and the relation between them, can be studied on a molecular length scale. (C) 2004 Published by Elsevier B.V."],["dc.identifier.doi","10.1016/j.physb.2004.04.060"],["dc.identifier.gro","3143964"],["dc.identifier.isi","000223285700033"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1536"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Science Bv"],["dc.publisher.place","Amsterdam"],["dc.relation.conference","3rd European Conference on Neutron Scattering (ECNS 2003)"],["dc.relation.eventlocation","Montpellier, FRANCE"],["dc.relation.ispartof","Physica B: Condensed Matter"],["dc.relation.issn","0921-4526"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","membrane biophysics"],["dc.title","Collective dynamics in phospholipid bilayers investigated by inelastic neutron scattering: exploring the dynamics of biological membranes with neutrons"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","722"],["dc.bibliographiccitation.lastpage","724"],["dc.bibliographiccitation.volume","385"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.contributor.author","Seydel, Tilo"],["dc.contributor.author","Haeubler, Wolfgang"],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:49:55Z"],["dc.date.available","2017-09-07T11:49:55Z"],["dc.date.issued","2006"],["dc.description.abstract","While most spectroscopic techniques, e.g., nuclear magnetic resonance or dielectric spectroscopy probe macroscopic responses, neutron and with some restrictions also X-ray scattering experiments give unique access to microscopic dynamics at length scales of intermolecular or atomic distances. Only recently, it has become possible to study collective dynamics of planar lipid bilayers using neutron spectroscopy techniques [M.C. Rheinstadter, et al., Phys. Rev. Lett. 93 (2004) 108107]. We determined the dispersion relation of the coherent fast picosecond density fluctuations on nearest-neighbor distances of the phospholipid acyl chains in the gel and in the fluid phases of a DMPC bilayer. The experiments shed light on the evolution of structure and dynamics, and the relation between them, in the range of the gel-fluid main phase transition. The scattering volume restriction for inelastic neutron experiments was overcome by stacking several thousand highly aligned membrane bilayers. By combining different neutron scattering techniques, namely three-axis, backscattering and spin-echo spectroscopy, we present measurements of short and long wavelength collective fluctuations in biomimetic and biological membranes in a large range in momentum and energy transfer, covering time scales from about 0.1 ps to almost 1 mu s and length scales from 3 angstrom to about 0.1 mu m. The neutron backscattering technique gives information about slow molecular dynamics of lipid acyl chains and the 'membrane-water', i.e., the water molecules in between the stacked bilayers in the nanosecond time range [M.C. Rheinstadter, et al., Phys. Rev. E 71 (2005) 061908]. The dispersion relations of the long wavelength undulation modes in lipid bilayers with nanosecond relaxation times can be determined by quasielastic reflectometry on spin-echo spectrometers and give direct access to the elasticity parameters of the membranes. [M.C. Rheinstadter, et al., cond-mat/0606114]. (c) 2006 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.physb.2006.06.029"],["dc.identifier.gro","3143592"],["dc.identifier.isi","000243096400214"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1122"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Science Bv"],["dc.publisher.place","Amsterdam"],["dc.relation.eventlocation","Sydney, AUSTRALIA"],["dc.relation.ispartof","Physica B: Condensed Matter"],["dc.relation.issn","0921-4526"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","membrane biophysics"],["dc.title","The 'neutron window' of collective excitations in lipid membranes"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3156"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Biophysical Journal"],["dc.bibliographiccitation.lastpage","3168"],["dc.bibliographiccitation.volume","93"],["dc.contributor.author","Hub, Jochen S."],["dc.contributor.author","Salditt, Tim"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.contributor.author","Groot, Bert L. de"],["dc.date.accessioned","2017-09-07T11:49:23Z"],["dc.date.available","2017-09-07T11:49:23Z"],["dc.date.issued","2007"],["dc.description.abstract","We present an extensive comparison of short-range order and short wavelength dynamics of a hydrated phospholipid bilayer derived by molecular dynamics simulations, elastic x-ray, and inelastic neutron scattering experiments. The quantities that are compared between simulation and experiment include static and dynamic structure factors, reciprocal space mappings, and electron density profiles. We show that the simultaneous use of molecular dynamics and diffraction data can help to extract real space properties like the area per lipid and the lipid chain ordering from experimental data. In addition, we assert that the interchain distance can be computed to high accuracy from the interchain correlation peak of the structure factor. Moreover, it is found that the position of the interchain correlation peak is not affected by the area per lipid, while its correlation length decreases linearly with the area per lipid. This finding allows us to relate a property of the structure factor quantitatively to the area per lipid. Finally, the short wavelength dynamics obtained from the simulations and from inelastic neutron scattering are analyzed and compared. The conventional interpretation in terms of the three-effective-eigenmode model is found to be only partly suitable to describe the complex fluid dynamics of lipid chains."],["dc.identifier.doi","10.1529/biophysj.107.104885"],["dc.identifier.gro","3143414"],["dc.identifier.isi","000250199300020"],["dc.identifier.pmid","17631531"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/926"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.eissn","1542-0086"],["dc.relation.issn","0006-3495"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","x-ray scattering"],["dc.subject.gro","membrane biophysics"],["dc.title","Short-range order and collective dynamics of DMPC bilayers: A comparison between molecular dynamics simulations, X-ray, and neutron scattering experiments"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","901"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","European Biophysics Journal"],["dc.bibliographiccitation.lastpage","913"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","Armstrong, Clare L."],["dc.contributor.author","Barrett, Matthew A."],["dc.contributor.author","Hiess, Arno"],["dc.contributor.author","Salditt, Tim"],["dc.contributor.author","Katsaras, John"],["dc.contributor.author","Shi, An-Chang"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.date.accessioned","2017-09-07T11:48:24Z"],["dc.date.available","2017-09-07T11:48:24Z"],["dc.date.issued","2012"],["dc.description.abstract","Inelastic neutron scattering was used to study the effect of 5 and 40 mol% cholesterol on the lateral nanoscale dynamics of phospholipid membranes. By measuring the excitation spectrum at several lateral q "],["dc.identifier.doi","10.1007/s00249-012-0826-4"],["dc.identifier.gro","3142459"],["dc.identifier.isi","000309475700012"],["dc.identifier.pmid","22729214"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8518"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.eissn","1432-1017"],["dc.relation.issn","0175-7571"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","membrane biophysics"],["dc.title","Effect of cholesterol on the lateral nanoscale dynamics of fluid membranes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","048103"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Physical Review Letters"],["dc.bibliographiccitation.volume","97"],["dc.contributor.author","Rheinstädter, Maikel C."],["dc.contributor.author","Haeussler, Wolfgang"],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:52:39Z"],["dc.date.available","2017-09-07T11:52:39Z"],["dc.date.issued","2006"],["dc.description.abstract","We have studied the mesoscopic shape fluctuations in aligned multilamellar stacks of 1,2-dimyristoyl-sn-glycero-3-phoshatidylcholine bilayers using the neutron spin-echo technique. The corresponding in plane dispersion relation tau(-1)(q(vertical bar vertical bar)) at different temperatures in the gel (ripple, P-beta(')) and the fluid (L-alpha) phase of this model system has been determined. Two relaxation processes, one at about 10 ns and a second, slower process at about 100 ns can be quantified. The dispersion relation in the fluid phase is fitted to a smectic hydrodynamic theory, with a correction for finite q(z) resolution. We extract values for the bilayer bending rigidity kappa, the compressional modulus of the stacks B, and the effective sliding viscosity eta(3). The softening of a mode which can be associated with the formation of the ripple structure is observed close to the main phase transition."],["dc.identifier.doi","10.1103/PhysRevLett.97.048103"],["dc.identifier.gro","3143654"],["dc.identifier.isi","000239377500063"],["dc.identifier.pmid","16907615"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1192"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","0031-9007"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","membrane biophysics"],["dc.title","Dispersion relation of lipid membrane shape fluctuations by neutron spin-echo spectrometry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]