Salditt, Tim

[["dc.bibliographiccitation.firstpage","2"],["dc.contributor.author","Eckermann, Marina"],["dc.contributor.author","Salditt, Tim"],["dc.contributor.editor","Müller, Bert"],["dc.contributor.editor","Wang, Ge"],["dc.date.accessioned","2022-02-16T14:12:05Z"],["dc.date.available","2022-02-16T14:12:05Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1117/12.2596133"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/99930"],["dc.relation.conference","SPIE Optical Engineering + Applications"],["dc.relation.eventend","2021-08-05"],["dc.relation.eventlocation","San Diego, California"],["dc.relation.eventstart","2021-08-01"],["dc.relation.isbn","9781510645189"],["dc.relation.isbn","9781510645196"],["dc.relation.ispartof","Developments in X-Ray Tomography XIII"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","biomedical tomography"],["dc.title","Towards correlative imaging of neuronal tissue by phase-contrast x-ray tomography and SEM"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.volume","12242"],["dc.contributor.author","Reichmann, Jakob"],["dc.contributor.author","Ruhwedel, Torben"],["dc.contributor.author","Möbius, Wiebke"],["dc.contributor.author","Salditt, Tim"],["dc.contributor.editor","Müller, Bert"],["dc.contributor.editor","Wang, Ge"],["dc.date.accessioned","2022-12-07T11:46:36Z"],["dc.date.available","2022-12-07T11:46:36Z"],["dc.date.issued","2022-10-14"],["dc.identifier.doi","10.1117/12.2627682"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/118460"],["dc.language.iso","en"],["dc.publisher.place","Proc. SPIE 12242"],["dc.relation","SFB 1456 | Cluster A | A03: Dimensionality reduction and regression in Wasserstein space for quantitative 3D histology"],["dc.relation","SFB 1456: Mathematik des Experiments: Die Herausforderung indirekter Messungen in den Naturwissenschaften"],["dc.relation.conference","SPIE Optical Engineering + Applications, Developments in X-Ray Tomography XIV"],["dc.relation.eventend","2022-08-26"],["dc.relation.eventlocation","San Diego"],["dc.relation.eventstart","2022-08-21"],["dc.relation.isbn","9781510654686"],["dc.relation.isbn","9781510654693"],["dc.relation.ispartof","Proceeding of SPIE"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.title","Neodymium acetate as a contrast agent for x-ray phase-contrast tomography"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3"],["dc.bibliographiccitation.volume","11113"],["dc.contributor.author","Robisch, Anna Lena"],["dc.contributor.author","Eckermann, Marina"],["dc.contributor.author","Töpperwien, Mareike"],["dc.contributor.author","Meer, Franziska van der"],["dc.contributor.author","Stadelmann-Nessler, Christine"],["dc.contributor.author","Salditt, Tim"],["dc.contributor.editor","Müller, Bert"],["dc.contributor.editor","Wang, Ge"],["dc.date.accessioned","2020-04-23T12:45:49Z"],["dc.date.available","2020-04-23T12:45:49Z"],["dc.date.issued","2019"],["dc.description.abstract","X-ray cone-beam holo-tomography of unstained tissue from the human central nervous system reveals details down to sub-cellular length scales.1 This visualization of variations in the electron density of the sample is based on phase contrast techniques using intensities formed by self-interference of the beam between object and detector. Phase retrieval inverts diffraction and overcomes the phase problem by constraints such as several measurements at different Fresnel numbers for a single projection. Therefore, the object-to-detector distance (defocus) can be varied. However, for cone beam geometry, changing defocus changes magnification, which can be problematic in view of image processing and resolution. Alternatively, the photon energy can be altered (multi-E). Far from absorption edges, multi-E data yield the wavelength independent electron density. In this contribution we present multi-E holo-tomography at the GINIX setup of the P10 beamline at DESY. The instrument is based on a combined optics of elliptical mirrors and an x-ray waveguide positioned in the focal plane for further coherence, spatial Filtering and high numerical aperture.2 Previous results showed the suitability of this instrument for nanoscale tomography of unstained brain tissue.1 We demonstrate that upon energy variation, the focal spot is stable enough for imaging. To this end, a double crystal monochromator and automated alignment routines are required. Three tomograms of human brain tissue were recorded and jointly analyzed using phase retrieval based on the contrast transfer function formalism generalized to multiple photon energies. Variations of the electron density of the sample are successfully reconstructed. © (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only."],["dc.identifier.doi","10.1117/12.2529041"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/64294"],["dc.language.iso","en"],["dc.notes.preprint","yes"],["dc.relation.eisbn","978-1-5106-2920-2"],["dc.relation.eventend","2019-09"],["dc.relation.eventlocation","San Diego"],["dc.relation.eventstart","2019-09"],["dc.relation.isbn","978-1-5106-2919-6"],["dc.relation.iserratumof","yes"],["dc.title","Nanoscale x-ray holo-tomography of human brain tissue with phase retrieval based on multiphoton energy recordings"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Töpperwien, Mareike"],["dc.contributor.author","Krenkel, Martin"],["dc.contributor.author","Müller, Kristin"],["dc.contributor.author","Salditt, Tim"],["dc.contributor.editor","Stock, Stuart R."],["dc.contributor.editor","Müller, Bert"],["dc.contributor.editor","Wang, Ge"],["dc.date.accessioned","2017-09-07T11:54:06Z"],["dc.date.available","2017-09-07T11:54:06Z"],["dc.date.issued","2016"],["dc.description.abstract","Assessing the three-dimensional architecture of neuronal tissues with sub-cellular resolution presents a significant analytical challenge. Overcoming the limitations associated with serial slicing, phase-contrast x-ray tomography has the potential to contribute to this goal. Even compact laboratory CT at an optimized liquid-metal jet micro- focus source combined with suitable phase-retrieval algorithms and preparation protocols can yield renderings with single cell sensitivity in millimeter sized brain areas of mouse. Here, we show the capabilities of the setup by imaging a Golgi-Cox impregnated mouse brain. Towards higher resolution we extend these studies at our recently upgraded waveguide-based cone-beam holo-tomography instrument GINIX at DESY. This setup allows high resolution recordings with adjustable field of view and resolution, down to the voxel sizes in the range of a few ten nanometers. The recent results make us confident that important issues of neuronal connectivity can be addressed by these methods, and that 3D (virtual) histology with nanoscale resolution will become an attractive modality for neuroscience research."],["dc.identifier.doi","10.1117/12.2238496"],["dc.identifier.gro","3145108"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/2808"],["dc.language.iso","en"],["dc.notes.intern","Crossref Import"],["dc.notes.status","public"],["dc.publisher","SPIE-Intl Soc Optical Eng"],["dc.publisher.place","Bellingham, Washington"],["dc.relation.conference","Developments in X-Ray Tomography X"],["dc.relation.eventend","2016-08-31"],["dc.relation.eventlocation","San Diego, Calif."],["dc.relation.eventstart","2016-08-29"],["dc.relation.isbn","978-1-5106-0325-7"],["dc.relation.ispartof","Developments in X-Ray Tomography X"],["dc.relation.issn","0277-786X"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.subject.gro","x-ray imaging"],["dc.subject.gro","biomedical tomography"],["dc.title","Phase-contrast tomography of neuronal tissues: from laboratory- to high resolution synchrotron CT"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]