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  • 2021-11-08Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","171"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Endodontics"],["dc.bibliographiccitation.lastpage","178"],["dc.bibliographiccitation.volume","48"],["dc.contributor.author","Frank, Ariadne Charis"],["dc.contributor.author","Kanzow, Philipp"],["dc.contributor.author","Rödig, Tina"],["dc.contributor.author","Wiegand, Annette"],["dc.date.accessioned","2021-12-01T09:23:00Z"],["dc.date.available","2021-12-01T09:23:00Z"],["dc.date.issued","2021-11-08"],["dc.description.abstract","Introduction: The aim of this study was to analyze and compare the efficacy of different bleaching agents typically used for internal bleaching of endodontically treated discolored teeth.\r\nMethods: Electronic databases (PubMed, Web of Science, and Cochrane Library) were searched by 2 reviewers for clinical trials in which the color of endodontically treated discolored teeth before and after internal bleaching was examined using shade guide units (ΔSGU) or a spectrophotometer/colorimeter (ΔE). The efficacies of the bleaching agents were compared using subgroup analyses. Statistical heterogeneity was assessed with the Cochran Q test and I2 statistic. Publication bias was evaluated using funnel plots.\r\nResults: Eight studies were included in the systematic review, 6 of which could be included in the meta-analyses. Internal bleaching led to a significant change in tooth shade (ΔSGU: 6.27 [95% confidence interval, 5.36-7.17], ΔE: 12.83 [95% confidence interval, 9.46-16.20]). With regard to ΔSGU, the use of carbamide peroxide (35% or 37%), hydrogen peroxide (35%), and the combination of sodium perborate and hydrogen peroxide (3% or 30%) led to a better bleaching effect than sodium perborate (adjusted P value ≤ .026). Regarding ΔE, there were no significant differences between carbamide peroxide (37%), hydrogen peroxide (35%), and sodium perborate mixed with hydrogen peroxide (P = .051). The risk of bias of the included studies was classified as moderate to high.\r\nConclusions: Carbamide peroxide, hydrogen peroxide, and sodium perborate have a significant bleaching effect on discolored, root canal-treated teeth. For a valid assessment of shade stability and a comparison of bleaching agents and their concentrations, further studies with long-term recalls are necessary."],["dc.identifier.doi","10.1016/j.joen.2021.10.011"],["dc.identifier.pii","S0099239921007925"],["dc.identifier.pmid","34762968"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/94535"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-478"],["dc.relation.issn","0099-2399"],["dc.relation.orgunit","Poliklinik für Präventive Zahnmedizin, Parodontologie und Kariologie"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.subject.gro","bleaching"],["dc.subject.gro","color change"],["dc.subject.gro","discoloration"],["dc.subject.gro","nonvital teeth"],["dc.subject.gro","walking bleach technique"],["dc.title","Comparison of the bleaching efficacy of different agents used for internal bleaching – a systematic review and meta-analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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