Schneider, Anja

[["dc.bibliographiccitation.firstpage","124"],["dc.bibliographiccitation.journal","Cortex"],["dc.bibliographiccitation.lastpage","135"],["dc.bibliographiccitation.volume","83"],["dc.contributor.author","Teipel, Stefan J."],["dc.contributor.author","Raiser, Theresa"],["dc.contributor.author","Riedl, Lina"],["dc.contributor.author","Riederer, Isabelle"],["dc.contributor.author","Schroeter, Matthias L."],["dc.contributor.author","Bisenius, Sandrine"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Kornhuber, Johannes"],["dc.contributor.author","Fliessbach, Klaus"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Grothe, Michel J."],["dc.contributor.author","Prudlo, Johannes"],["dc.contributor.author","Kassubek, Jan"],["dc.contributor.author","Ludolph, Albert C."],["dc.contributor.author","Landwehrmeyer, Bernhard G."],["dc.contributor.author","Anderl-Straub, Sarah"],["dc.contributor.author","Otto, Markus"],["dc.contributor.author","Danek, Adrian"],["dc.date.accessioned","2018-11-07T10:07:28Z"],["dc.date.available","2018-11-07T10:07:28Z"],["dc.date.issued","2016"],["dc.description.abstract","Primary progressive aphasia (PPA) is characterized by profound destruction of cortical language areas. Anatomical studies suggest an involvement of cholinergic basal forebrain (BF) in PPA syndromes, particularly in the area of the nucleus subputaminalis (NSP). Here we aimed to determine the pattern of atrophy and structural covariance as a proxy of structural connectivity of BF nuclei in PPA variants. We studied 62 prospectively recruited cases with the clinical diagnosis of PPA and 31 healthy older control participants from the cohort study of the German consortium for frontotemporal lobar. degeneration (FTLD). We determined cortical and BF atrophy based on high-resolution magnetic resonance imaging (MRI) scans. Patterns of structural covariance of BF with cortical regions were determined using voxel-based partial least square analysis. We found significant atrophy of total BF and BF subregions in PPA patients compared with controls [F(1, 82) = 20.2, p < .001]. Atrophy was most pronounced in the NSP and the posterior BF, and most severe in the semantic variant and the nonfluent variant of PPA. Structural covariance analysis in healthy controls revealed associations of the BF nuclei, particularly the NSP, with left hemispheric predominant prefrontal, lateral temporal, and parietal cortical areas, including Broca's speech area (p < .001, permutation test). In contrast, the PPA patients showed preserved structural covariance of the BF nuclei mostly with right but not with left hemispheric cortical areas (p < .001, permutation test). Our findings agree with the neuroanatomically proposed involvement of the cholinergic BF, particularly the NSP, in PPA syndromes. We found a shift from a structural covariance of the BF with left hemispheric cortical areas in healthy aging towards right hemispheric cortical areas in PPA, possibly reflecting a consequence of the profound and early destruction of cortical language areas in PPA. (C) 2016 The Author(s). Published by Elsevier Ltd."],["dc.identifier.doi","10.1016/j.cortex.2016.07.004"],["dc.identifier.isi","000385599300011"],["dc.identifier.pmid","27509365"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14211"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39287"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.eissn","0010-9452"],["dc.relation.issn","1973-8102"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Atrophy and structural covariance of the cholinergic basal forebrain in primary progressive aphasia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1118"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Annals of Neurology"],["dc.bibliographiccitation.lastpage","1131"],["dc.bibliographiccitation.volume","88"],["dc.contributor.author","Tetreault, Aaron M."],["dc.contributor.author","Phan, Tony"],["dc.contributor.author","Petersen, Kalen J."],["dc.contributor.author","Claassen, Daniel O."],["dc.contributor.author","Neth, Byran J."],["dc.contributor.author","Graff‐Radford, Jonathan"],["dc.contributor.author","Albrecht, Franziska"],["dc.contributor.author","Fliessbach, Klaus"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Synofzik, Matthis"],["dc.contributor.author","Diehl‐Schmid, Janine"],["dc.contributor.author","Otto, Markus"],["dc.contributor.author","Schroeter, Matthias L."],["dc.contributor.author","Darby, Richard Ryan"],["dc.date.accessioned","2021-04-14T08:32:24Z"],["dc.date.available","2021-04-14T08:32:24Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1002/ana.25901"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83907"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1531-8249"],["dc.relation.issn","0364-5134"],["dc.title","Network Localization of Alien Limb in Patients with Corticobasal Syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","945709"],["dc.bibliographiccitation.journal","Frontiers in Psychology"],["dc.bibliographiccitation.volume","13"],["dc.contributor.affiliation","Böttcher, Adriana; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Zarucha, Alexis; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Köbe, Theresa; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Gaubert, Malo; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Höppner, Angela; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Altenstein, Slawek; 3German Center for Neurodegenerative Diseases, Berlin, Germany"],["dc.contributor.affiliation","Bartels, Claudia; 5Department of Psychiatry and Psychotherapy, University Medical Center, University of Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Buerger, Katharina; 6Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany"],["dc.contributor.affiliation","Dechent, Peter; 8MR-Research in Neurology and Psychiatry, Georg-August-University Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Dobisch, Laura; 9German Center for Neurodegenerative Diseases, Magdeburg, Germany"],["dc.contributor.affiliation","Ewers, Michael; 7German Center for Neurodegenerative Diseases, Munich, Germany"],["dc.contributor.affiliation","Fliessbach, Klaus; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Freiesleben, Silka Dawn; 4Department of Psychiatry, Charité – Universitätsmedizin Berlin, Berlin, Germany"],["dc.contributor.affiliation","Frommann, Ingo; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Haynes, John Dylan; 13Bernstein Center for Computational Neuroscience, Charité – Universitätsmedizin, Berlin, Germany"],["dc.contributor.affiliation","Janowitz, Daniel; 6Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany"],["dc.contributor.affiliation","Kilimann, Ingo; 14German Center for Neurodegenerative Diseases, Rostock, Germany"],["dc.contributor.affiliation","Kleineidam, Luca; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Laske, Christoph; 16German Center for Neurodegenerative Diseases, Tübingen, Germany"],["dc.contributor.affiliation","Maier, Franziska; 18Department of Psychiatry, Faculty of Medicine, University of Cologne, Cologne, Germany"],["dc.contributor.affiliation","Metzger, Coraline; 9German Center for Neurodegenerative Diseases, Magdeburg, Germany"],["dc.contributor.affiliation","Munk, Matthias H. J.; 16German Center for Neurodegenerative Diseases, Tübingen, Germany"],["dc.contributor.affiliation","Perneczky, Robert; 7German Center for Neurodegenerative Diseases, Munich, Germany"],["dc.contributor.affiliation","Peters, Oliver; 3German Center for Neurodegenerative Diseases, Berlin, Germany"],["dc.contributor.affiliation","Priller, Josef; 3German Center for Neurodegenerative Diseases, Berlin, Germany"],["dc.contributor.affiliation","Rauchmann, Boris-Stephan; 23Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany"],["dc.contributor.affiliation","Roy, Nina; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Scheffler, Klaus; 25Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany"],["dc.contributor.affiliation","Schneider, Anja; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Spottke, Annika; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Teipel, Stefan J.; 14German Center for Neurodegenerative Diseases, Rostock, Germany"],["dc.contributor.affiliation","Wiltfang, Jens; 5Department of Psychiatry and Psychotherapy, University Medical Center, University of Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Wolfsgruber, Steffen; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Yakupov, Renat; 9German Center for Neurodegenerative Diseases, Magdeburg, Germany"],["dc.contributor.affiliation","Düzel, Emrah; 9German Center for Neurodegenerative Diseases, Magdeburg, Germany"],["dc.contributor.affiliation","Jessen, Frank; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Röske, Sandra; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Wagner, Michael; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Kempermann, Gerd; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Wirth, Miranka; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.author","Böttcher, Adriana"],["dc.contributor.author","Zarucha, Alexis"],["dc.contributor.author","Köbe, Theresa"],["dc.contributor.author","Gaubert, Malo"],["dc.contributor.author","Höppner, Angela"],["dc.contributor.author","Altenstein, Slawek"],["dc.contributor.author","Bartels, Claudia"],["dc.contributor.author","Buerger, Katharina"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Dobisch, Laura"],["dc.contributor.author","Wirth, Miranka"],["dc.contributor.author","Ewers, Michael"],["dc.contributor.author","Fliessbach, Klaus"],["dc.contributor.author","Freiesleben, Silka Dawn"],["dc.contributor.author","Frommann, Ingo"],["dc.contributor.author","Haynes, John Dylan"],["dc.contributor.author","Janowitz, Daniel"],["dc.contributor.author","Kilimann, Ingo"],["dc.contributor.author","Kleineidam, Luca"],["dc.contributor.author","Laske, Christoph"],["dc.contributor.author","Maier, Franziska"],["dc.contributor.author","Metzger, Coraline"],["dc.contributor.author","Munk, Matthias H. J."],["dc.contributor.author","Perneczky, Robert"],["dc.contributor.author","Peters, Oliver"],["dc.contributor.author","Priller, Josef"],["dc.contributor.author","Rauchmann, Boris-Stephan"],["dc.contributor.author","Roy, Nina"],["dc.contributor.author","Scheffler, Klaus"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Teipel, Stefan J."],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Wolfsgruber, Steffen"],["dc.contributor.author","Yakupov, Renat"],["dc.contributor.author","Düzel, Emrah"],["dc.contributor.author","Jessen, Frank"],["dc.contributor.author","Röske, Sandra"],["dc.contributor.author","Wagner, Michael"],["dc.contributor.author","Kempermann, Gerd"],["dc.date.accessioned","2022-10-04T10:21:56Z"],["dc.date.available","2022-10-04T10:21:56Z"],["dc.date.issued","2022"],["dc.date.updated","2022-11-11T13:14:36Z"],["dc.description.abstract","Regular musical activity as a complex multimodal lifestyle activity is proposed to be protective against age-related cognitive decline and Alzheimer’s disease. This cross-sectional study investigated the association and interplay between musical instrument playing during life, multi-domain cognitive abilities and brain morphology in older adults (OA) from the DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE) study. Participants reporting having played a musical instrument across three life periods (\r\n n\r\n = 70) were compared to controls without a history of musical instrument playing (\r\n n\r\n = 70), well-matched for reserve proxies of education, intelligence, socioeconomic status and physical activity. Participants with musical activity outperformed controls in global cognition, working memory, executive functions, language, and visuospatial abilities, with no effects seen for learning and memory. The musically active group had greater gray matter volume in the somatosensory area, but did not differ from controls in higher-order frontal, temporal, or hippocampal volumes. However, the association between gray matter volume in distributed frontal-to-temporal regions and cognitive abilities was enhanced in participants with musical activity compared to controls. We show that playing a musical instrument during life relates to better late-life cognitive abilities and greater brain capacities in OA. Musical activity may serve as a multimodal enrichment strategy that could help preserve cognitive and brain health in late life. Longitudinal and interventional studies are needed to support this notion."],["dc.identifier.doi","10.3389/fpsyg.2022.945709"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114545"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-600"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1664-1078"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Aging Neuroscience"],["dc.bibliographiccitation.volume","13"],["dc.contributor.affiliation","Hansen, Niels; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Singh, Aditya; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Bartels, Claudia; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Brosseron, Frederic; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Buerger, Katharina; 5German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany"],["dc.contributor.affiliation","Cetindag, Arda C.; 7Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany"],["dc.contributor.affiliation","Dobisch, Laura; 9German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany"],["dc.contributor.affiliation","Dechent, Peter; 10MR-Research in Neurology and Psychiatry, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Ertl-Wagner, Birgit B.; 11Institute for Clinical Radiology, Ludwig-Maximilians-University, Munich, Germany"],["dc.contributor.affiliation","Fliessbach, Klaus; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Haynes, John D.; 12Bernstein Center for Computational Neuroscience, Charité—Universitätsmedizin, Berlin, Germany"],["dc.contributor.affiliation","Heneka, Michael T.; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Janowitz, Daniel; 6Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany"],["dc.contributor.affiliation","Kilimann, Ingo; 13German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany"],["dc.contributor.affiliation","Laske, Christoph; 15German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany"],["dc.contributor.affiliation","Metzger, Coraline D.; 9German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany"],["dc.contributor.affiliation","Munk, Matthias H.; 15German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany"],["dc.contributor.affiliation","Peters, Oliver; 7Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany"],["dc.contributor.affiliation","Priller, Josef; 8German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany"],["dc.contributor.affiliation","Roy, Nina; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Scheffler, Klaus; 21Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany"],["dc.contributor.affiliation","Schneider, Anja; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Spottke, Annika; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Spruth, Eike J.; 8German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany"],["dc.contributor.affiliation","Teipel, Stefan; 13German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany"],["dc.contributor.affiliation","Tscheuschler, Maike; 23Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany"],["dc.contributor.affiliation","Vukovich, Ruth; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Wiltfang, Jens; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Duezel, Emrah; 9German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany"],["dc.contributor.affiliation","Jessen, Frank; 23Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany"],["dc.contributor.affiliation","Goya-Maldonado, Roberto; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.author","Hansen, Niels"],["dc.contributor.author","Singh, Aditya"],["dc.contributor.author","Bartels, Claudia"],["dc.contributor.author","Brosseron, Frederic"],["dc.contributor.author","Buerger, Katharina"],["dc.contributor.author","Cetindag, Arda C."],["dc.contributor.author","Dobisch, Laura"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Ertl-Wagner, Birgit B."],["dc.contributor.author","Goya-Maldonado, Roberto"],["dc.contributor.author","Fliessbach, Klaus"],["dc.contributor.author","Haynes, John D."],["dc.contributor.author","Heneka, Michael T."],["dc.contributor.author","Janowitz, Daniel"],["dc.contributor.author","Kilimann, Ingo"],["dc.contributor.author","Laske, Christoph"],["dc.contributor.author","Metzger, Coraline D."],["dc.contributor.author","Munk, Matthias H."],["dc.contributor.author","Peters, Oliver"],["dc.contributor.author","Priller, Josef"],["dc.contributor.author","Roy, Nina"],["dc.contributor.author","Scheffler, Klaus"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Spruth, Eike J."],["dc.contributor.author","Teipel, Stefan"],["dc.contributor.author","Tscheuschler, Maike"],["dc.contributor.author","Vukovich, Ruth"],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Duezel, Emrah"],["dc.contributor.author","Jessen, Frank"],["dc.date.accessioned","2021-06-01T09:42:25Z"],["dc.date.available","2021-06-01T09:42:25Z"],["dc.date.issued","2021"],["dc.date.updated","2022-02-09T13:21:10Z"],["dc.description.abstract","Background: The hippocampus and its subfields (HippSub) are reported to be diminished in patients with Alzheimer's disease (AD), bipolar disorder (BD), and major depressive disorder (MDD). We examined these groups vs healthy controls (HC) to reveal HippSub alterations between diseases. Methods: We segmented 3T-MRI T2-weighted hippocampal images of 67 HC, 58 BD, and MDD patients from the AFFDIS study and 137 patients from the DELCODE study assessing cognitive decline, including subjective cognitive decline (SCD), amnestic mild cognitive impairment (aMCI), and AD, via Free Surfer 6.0 to compare volumes across groups. Results: Groups differed significantly in several HippSub volumes, particularly between patients with AD and mood disorders. In comparison to HC, significant lower volumes appear in aMCI and AD groups in specific subfields. Smaller volumes in the left presubiculum are detected in aMCI and AD patients, differing from the BD group. A significant linear regression is seen between left hippocampus volume and duration since the first depressive episode. Conclusions: HippSub volume alterations were observed in AD, but not in early-onset MDD and BD, reinforcing the notion of different neural mechanisms in hippocampal degeneration. Moreover, duration since the first depressive episode was a relevant factor explaining the lower left hippocampal volumes present in groups."],["dc.identifier.doi","10.3389/fnagi.2021.626974"],["dc.identifier.eissn","1663-4365"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85247"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1663-4365"],["dc.rights","http://creativecommons.org/licenses/by/4.0/"],["dc.rights.uri","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

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