Now showing 1 - 10 of 32
  • 2011Journal Article
    [["dc.bibliographiccitation.firstpage","347"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Annals of Thoracic and Cardiovascular Surgery"],["dc.bibliographiccitation.lastpage","351"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Mirzaie, Masoud"],["dc.contributor.author","Fatehpur, Sheila"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Sossalla, Samuel T."],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.date.accessioned","2018-11-07T08:53:26Z"],["dc.date.available","2018-11-07T08:53:26Z"],["dc.date.issued","2011"],["dc.description.abstract","Objective: The present paper exemplary describes several severe stenoses of supraaortic branches with its symptoms and operative treatments. Methods: Eight patients, two female (68 +/- 5 y), six male (73 +/- 4 y), were retrospectively evaluated. Patients showed neurological signs as followed: recurring attacks of vertigo (80%), temporary paresis of extremity (20%), speech disorders (20%) and subclavian and/or carotic-steel-syndrome (15%). Seven patients have already been previously treated with revascularization of the supraaortic branches in the past. The surgical techniques used were thrombendarterectomy of the internal carotid artery, carotid-subclavian bypass and complex aortotruncal, aorto-carotid and aorto-subclavian-bypass. Results: One patient died nine days postoperatively due to myocardial infarction. Mean duration of stay on intensive care unit was 1.5 days. Mean duration of postoperative ventilation was six hours. Average duration of stay on normal ward was nine days. Conclusion: This study presents several complex reconstructions of supraaortic branches, which were indicated in cases with severe stenoses of supraaortic branches. Even though treatment strategies were complex the peri- and postoperative complication rates are quite low. These therapeutic strategies were necessary to avoid severe neurological complications in these patients."],["dc.identifier.doi","10.5761/atcs.oa.09.01432"],["dc.identifier.isi","000294510200005"],["dc.identifier.pmid","21881320"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22408"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Medical Tribune Inc"],["dc.relation.issn","1341-1098"],["dc.title","Complex Reconstruction of Supraaortic Branches"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2010Journal Article
    [["dc.bibliographiccitation.firstpage","337"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Current Cardiology Reviews"],["dc.bibliographiccitation.lastpage","342"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Heidrich, Florian"],["dc.contributor.author","Schotola, Hanna"],["dc.contributor.author","F. Popov, Aron"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Schuenemann, Julia"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","O. Coskun, Kasim"],["dc.contributor.author","von Lewinski, Dirk"],["dc.contributor.author","Hinz, Jose"],["dc.contributor.author","D. Schmitto, Jan"],["dc.date.accessioned","2021-06-01T10:48:36Z"],["dc.date.available","2021-06-01T10:48:36Z"],["dc.date.issued","2010"],["dc.identifier.doi","10.2174/157340310793566073"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85994"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","1573-403X"],["dc.title","AMPK - Activated Protein Kinase and its Role in Energy Metabolism of the Heart"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019-01Journal Article
    [["dc.bibliographiccitation.firstpage","58"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Perfusion"],["dc.bibliographiccitation.lastpage","66"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Budde, Holger"],["dc.contributor.author","Riggert, Joachim"],["dc.contributor.author","Vormfelde, Steffen"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Friedrich, Martin G."],["dc.date.accessioned","2020-12-10T18:38:24Z"],["dc.date.available","2020-12-10T18:38:24Z"],["dc.date.issued","2019-01"],["dc.description.abstract","Background: Re-transfusion of autologous blood is an important aspect of intraoperative blood management. Hemolysis and platelet dysfunction due to turbulence in the blood suction system strongly impede later usage of suction blood for re-transfusion. The aim of this study was to analyze the effects of a novel surgical-blood suction system with an automatic control setup for minimization of turbulence in the blood flow. Methods: We compared the turbulence-controlled suction system (TCSS) with a conventional suction system and untreated control blood in vitro. Blood cell counts, hemolysis levels according to free hemoglobin (fHb) and platelet function were analyzed to determine the integrity of the suction blood. Results: In the conventional suction system, we found a strong increase of the fHb levels. In contrast, erythrocyte integrity was almost completely preserved when using the TCSS. We obtained similar results regarding platelet function. The expression of platelet glycoproteins, such as GP IIb/IIIa and P-selectin, native or after stimulation with ADP, were markedly impaired by the conventional system, but not by the TCSS. In addition, platelet aggregometry revealed significant platelet dysfunction in conventional suction blood, but less aggregation impairments were present in blood samples from the TCSS. Conclusion: Our findings on an in vitro assessment show major improvements in red blood cell integrity and platelet function of suction blood when using the TCSS compared to a conventional suction system. These results reflect a significant benefit for autologous re-transfusion. We suggest testing the TCSS in surgery for clinical evaluation."],["dc.identifier.doi","10.1177/0267659118790915"],["dc.identifier.eissn","1477-111X"],["dc.identifier.issn","0267-6591"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77305"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.publisher","SAGE Publications"],["dc.relation.eissn","1477-111X"],["dc.relation.issn","0267-6591"],["dc.title","The effect of a novel turbulence-controlled suction system in the prevention of hemolysis and platelet dysfunction in autologous surgery blood"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2022-06Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","107"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The Journal of Extra-Corporeal Technology"],["dc.bibliographiccitation.lastpage","114"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Iwanowski, Ireneusz"],["dc.contributor.author","Böckhaus, Jan"],["dc.contributor.author","Richardt, Pascal"],["dc.contributor.author","Kutschka, Ingo"],["dc.contributor.author","Hanekop, Gunnar G."],["dc.contributor.author","Friedrich, Martin"],["dc.date.accessioned","2022-09-01T12:04:06Z"],["dc.date.available","2022-09-01T12:04:06Z"],["dc.date.issued","2022-06"],["dc.description.abstract","Blood hemolysis caused by mechanical impact is a serious problem in medicine. In addition to the heart-lung machine (artificial surfaces, flow irritating connection points) which contributes to hemolysis, blood suction and surgical suction devices are influencing factors. Goal of our research is to develop best flow optimizing suction geometry that represents the best compromise between all influencing effects. Based on data that negative pressure and turbulence have a negative impact on blood components, 27 surgical suction tips have been examined for acoustic stress and negative pressure behavior. Furthermore, a dimensionless factor Q was introduced to assess the overall performance of the suction tips investigated."],["dc.identifier.doi","10.1182/ject-107-114"],["dc.identifier.pmid","35928337"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113991"],["dc.language.iso","en"],["dc.relation.issn","0022-1058"],["dc.title","A New Evaluation Q-Factor to Be Calculated for Suction Geometries as a Basis for Smooth Suction in the Operating Field to Ensure the Highest Possible Blood Integrity for Retransfusion Systems"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","927"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Artificial Organs"],["dc.bibliographiccitation.lastpage","932"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Hanekop, Gerd-Gunnar"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Friedrich, Martin G."],["dc.date.accessioned","2018-11-07T09:18:54Z"],["dc.date.available","2018-11-07T09:18:54Z"],["dc.date.issued","2013"],["dc.description.abstract","Renal blood flow (RBF) may vary during cardiopulmonary bypass and low flow may cause insufficient blood supply of the kidney triggering renal failure postoperatively. Still, a valid intraoperative method of continuous RBF measurement is not available. A new catheter combining thermodilution and intravascular Doppler was developed, first calibrated in an in vitro model, and the catheter specific constant was determined. Then, application of the device was evaluated in a pilot study in an adult cardiovascular population. The data of the clinical pilot study revealed high correlation between the flow velocities detected by intravascular Doppler and the RBF measured by thermodilution (Pearson's correlation range: 0.78 to 0.97). In conclusion, the RBF can be measured excellently in real time using the new catheter, even under cardiopulmonary bypass."],["dc.identifier.doi","10.1111/aor.12084"],["dc.identifier.isi","000328325300012"],["dc.identifier.pmid","23635326"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28509"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1525-1594"],["dc.relation.issn","0160-564X"],["dc.title","A New Device for Intraoperative Renal Blood Flow Measurement During Open-Heart Surgery: An Experimental Study and the Clinical Pilot Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","E174"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The Heart Surgery Forum"],["dc.bibliographiccitation.lastpage","E177"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Bougioukas, Ioannis G."],["dc.contributor.author","Friedrich, Martin G."],["dc.contributor.author","Danner, Bernhard C."],["dc.contributor.author","Schoendube, Friedrich A."],["dc.date.accessioned","2020-12-10T18:42:40Z"],["dc.date.available","2020-12-10T18:42:40Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1532/hsf.2893"],["dc.identifier.eissn","1522-6662"],["dc.identifier.issn","1098-3511"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17343"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78041"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Re-exploration Early after Cardiac Surgery in Adults: The Importance of Bleeding-Related Complications"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2010Journal Article
    [["dc.bibliographiccitation.artnumber","10"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Mokashi, Suyog A."],["dc.contributor.author","Hinterthaner, Marc"],["dc.contributor.author","Hanekop, Gerd-Gunnar"],["dc.contributor.author","Zwaka, Paul"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T08:45:05Z"],["dc.date.available","2018-11-07T08:45:05Z"],["dc.date.issued","2010"],["dc.description.abstract","A surgical fire is a serious complication not previously described in the literature with regard to the thoracic cavity. We report a case in which an intrathoracic fire developed following an air leak combined with high pressure oxygen ventilation in a patient with severe chronic obstructive pulmonary disease. The patient presented to our institution with diffuse coronary artery disease and angina pectoris. He was treated with coronary artery bypass graft surgery, including left internal thoracic artery harvesting. Additionally to this rare presentation of an intrathoracic fire, a brief review of surgical fires is included to this paper."],["dc.identifier.doi","10.1186/1749-8090-5-10"],["dc.identifier.isi","000275913300001"],["dc.identifier.pmid","20219127"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20350"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.title","Intrathoracic fire during preparation of the left internal thoracic artery for coronary artery bypass grafting"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2010Journal Article
    [["dc.bibliographiccitation.artnumber","57"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Mokashi, Suyog A."],["dc.contributor.author","Emmert, Alexander"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Wiese, Christoph Hermann"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T08:40:27Z"],["dc.date.available","2018-11-07T08:40:27Z"],["dc.date.issued","2010"],["dc.description.abstract","We present a case of a 77-year old female who had undergone a coronary artery bypass grafting with an aortic valve replacement and developed three month later a Methicillin-Resistant Staphylococcus aureus (MRSA) sternal wound infection which was successful treated with Daptomycin combined with vacuum-assisted closure (VAC)."],["dc.identifier.doi","10.1186/1749-8090-5-57"],["dc.identifier.isi","000282338800001"],["dc.identifier.pmid","20691034"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19234"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.title","Daptomycin as a possible new treatment option for surgical management of Methicillin-Resistant Staphylococcus aureus sternal wound infection after cardiac surgery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2011Journal Article
    [["dc.bibliographiccitation.firstpage","1103"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Artificial Organs"],["dc.bibliographiccitation.lastpage","1104"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Tempes, Tasso"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T08:50:09Z"],["dc.date.available","2018-11-07T08:50:09Z"],["dc.date.issued","2011"],["dc.description.abstract","Renal failure after open heart surgery is a serious complication even in the pediatric population. The aim of the present study was to analyze morphological changes after cardiopulmonary bypass (CPB) surgery in a neonatal piglet model. The kidneys of newborn piglets sacrificed 6 h after CPB were examined (CPB; n = 4) regarding tubular dilatation, vacuole formation, leukocytic infiltration, epithelial destruction, and interstitial edema. Thereafter, the findings were compared with the morphology of normal (untreated) neonatal piglet kidneys (control; n = 4). All changes but the interstitial edema were statistically significant if compared with the normal renal tissue: tubular dilatation (CPB vs. control P < 0.05), vacuole formation (CPB vs. control P < 0.05), leukocytic infiltration (CPB vs. control P < 0.05), and epithelial destruction (CPB vs. control P < 0.001). In conclusion, CPB induces significant changes in the morphology of the neonatal piglet kidneys."],["dc.identifier.doi","10.1111/j.1525-1594.2011.01364.x"],["dc.identifier.isi","000297201200017"],["dc.identifier.pmid","21973032"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21631"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0160-564X"],["dc.title","Cardiopulmonary Bypass and Its Direct Effects on Neonatal Piglet Kidney Morphology"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","502"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Vascular and Endovascular Surgery"],["dc.bibliographiccitation.lastpage","506"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Danner, Bernhard Christoph"],["dc.contributor.author","Bougioukas, Ioannis"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Stojanovic, Tomislav"],["dc.date.accessioned","2018-11-07T09:19:26Z"],["dc.date.available","2018-11-07T09:19:26Z"],["dc.date.issued","2013"],["dc.description.abstract","Objective: We conducted a retrospective study to compare short- and mid-term patencies of Viabahn with surgical above-knee prosthetic bypass (pAKB). Methods: The records of 52 patients with either pAKB (n = 25) or Viabahn (n = 27) were reviewed. The majority had Rutherford clinical grade 3. Patients were followed after 3, 6, and 12 months and yearly thereafter. Results: For Viabahn, the short-term (1-16 months) primary patency rate was 60% with a secondary patency rate of 90%, and mid-term (1-68 months) patencies of 47% and 83.3%, respectively. In pAKB, the short-term results revealed a primary patency rate of 78% with a secondary patency of 91% and mid-term results of 65% and 90%, respectively. No statistical difference was found concerning short-term patencies. Mid-term primary patency was lower for Viabahn (P < .05) and secondary patency proved no significant difference. Conclusion: Viabahn revealed similar short-term primary and secondary patencies but lower mid-term primary patency. It provides a good alternative therapy to pAKB."],["dc.identifier.doi","10.1177/1538574413495964"],["dc.identifier.isi","000324591400002"],["dc.identifier.pmid","23867203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28635"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Inc"],["dc.relation.issn","1938-9116"],["dc.relation.issn","1538-5744"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Is There an Alternative to the Surgical Above-Knee Bypass in Treatment of Superficial Femoral Artery Disease? Experiences With Viabahn Stent Graft"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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