Friedrich, Martin

[["dc.bibliographiccitation.firstpage","347"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Annals of Thoracic and Cardiovascular Surgery"],["dc.bibliographiccitation.lastpage","351"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Mirzaie, Masoud"],["dc.contributor.author","Fatehpur, Sheila"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Sossalla, Samuel T."],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.date.accessioned","2018-11-07T08:53:26Z"],["dc.date.available","2018-11-07T08:53:26Z"],["dc.date.issued","2011"],["dc.description.abstract","Objective: The present paper exemplary describes several severe stenoses of supraaortic branches with its symptoms and operative treatments. Methods: Eight patients, two female (68 +/- 5 y), six male (73 +/- 4 y), were retrospectively evaluated. Patients showed neurological signs as followed: recurring attacks of vertigo (80%), temporary paresis of extremity (20%), speech disorders (20%) and subclavian and/or carotic-steel-syndrome (15%). Seven patients have already been previously treated with revascularization of the supraaortic branches in the past. The surgical techniques used were thrombendarterectomy of the internal carotid artery, carotid-subclavian bypass and complex aortotruncal, aorto-carotid and aorto-subclavian-bypass. Results: One patient died nine days postoperatively due to myocardial infarction. Mean duration of stay on intensive care unit was 1.5 days. Mean duration of postoperative ventilation was six hours. Average duration of stay on normal ward was nine days. Conclusion: This study presents several complex reconstructions of supraaortic branches, which were indicated in cases with severe stenoses of supraaortic branches. Even though treatment strategies were complex the peri- and postoperative complication rates are quite low. These therapeutic strategies were necessary to avoid severe neurological complications in these patients."],["dc.identifier.doi","10.5761/atcs.oa.09.01432"],["dc.identifier.isi","000294510200005"],["dc.identifier.pmid","21881320"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22408"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Medical Tribune Inc"],["dc.relation.issn","1341-1098"],["dc.title","Complex Reconstruction of Supraaortic Branches"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","337"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Current Cardiology Reviews"],["dc.bibliographiccitation.lastpage","342"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Heidrich, Florian"],["dc.contributor.author","Schotola, Hanna"],["dc.contributor.author","F. Popov, Aron"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Schuenemann, Julia"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","O. Coskun, Kasim"],["dc.contributor.author","von Lewinski, Dirk"],["dc.contributor.author","Hinz, Jose"],["dc.contributor.author","D. Schmitto, Jan"],["dc.date.accessioned","2021-06-01T10:48:36Z"],["dc.date.available","2021-06-01T10:48:36Z"],["dc.date.issued","2010"],["dc.identifier.doi","10.2174/157340310793566073"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85994"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","1573-403X"],["dc.title","AMPK - Activated Protein Kinase and its Role in Energy Metabolism of the Heart"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","107"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The Journal of Extra-Corporeal Technology"],["dc.bibliographiccitation.lastpage","114"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Iwanowski, Ireneusz"],["dc.contributor.author","Böckhaus, Jan"],["dc.contributor.author","Richardt, Pascal"],["dc.contributor.author","Kutschka, Ingo"],["dc.contributor.author","Hanekop, Gunnar G."],["dc.contributor.author","Friedrich, Martin"],["dc.date.accessioned","2022-09-01T12:04:06Z"],["dc.date.available","2022-09-01T12:04:06Z"],["dc.date.issued","2022-06"],["dc.description.abstract","Blood hemolysis caused by mechanical impact is a serious problem in medicine. In addition to the heart-lung machine (artificial surfaces, flow irritating connection points) which contributes to hemolysis, blood suction and surgical suction devices are influencing factors. Goal of our research is to develop best flow optimizing suction geometry that represents the best compromise between all influencing effects. Based on data that negative pressure and turbulence have a negative impact on blood components, 27 surgical suction tips have been examined for acoustic stress and negative pressure behavior. Furthermore, a dimensionless factor Q was introduced to assess the overall performance of the suction tips investigated."],["dc.identifier.doi","10.1182/ject-107-114"],["dc.identifier.pmid","35928337"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113991"],["dc.language.iso","en"],["dc.relation.issn","0022-1058"],["dc.title","A New Evaluation Q-Factor to Be Calculated for Suction Geometries as a Basis for Smooth Suction in the Operating Field to Ensure the Highest Possible Blood Integrity for Retransfusion Systems"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","927"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Artificial Organs"],["dc.bibliographiccitation.lastpage","932"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Hanekop, Gerd-Gunnar"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Friedrich, Martin G."],["dc.date.accessioned","2018-11-07T09:18:54Z"],["dc.date.available","2018-11-07T09:18:54Z"],["dc.date.issued","2013"],["dc.description.abstract","Renal blood flow (RBF) may vary during cardiopulmonary bypass and low flow may cause insufficient blood supply of the kidney triggering renal failure postoperatively. Still, a valid intraoperative method of continuous RBF measurement is not available. A new catheter combining thermodilution and intravascular Doppler was developed, first calibrated in an in vitro model, and the catheter specific constant was determined. Then, application of the device was evaluated in a pilot study in an adult cardiovascular population. The data of the clinical pilot study revealed high correlation between the flow velocities detected by intravascular Doppler and the RBF measured by thermodilution (Pearson's correlation range: 0.78 to 0.97). In conclusion, the RBF can be measured excellently in real time using the new catheter, even under cardiopulmonary bypass."],["dc.identifier.doi","10.1111/aor.12084"],["dc.identifier.isi","000328325300012"],["dc.identifier.pmid","23635326"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28509"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1525-1594"],["dc.relation.issn","0160-564X"],["dc.title","A New Device for Intraoperative Renal Blood Flow Measurement During Open-Heart Surgery: An Experimental Study and the Clinical Pilot Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","10"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Mokashi, Suyog A."],["dc.contributor.author","Hinterthaner, Marc"],["dc.contributor.author","Hanekop, Gerd-Gunnar"],["dc.contributor.author","Zwaka, Paul"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T08:45:05Z"],["dc.date.available","2018-11-07T08:45:05Z"],["dc.date.issued","2010"],["dc.description.abstract","A surgical fire is a serious complication not previously described in the literature with regard to the thoracic cavity. We report a case in which an intrathoracic fire developed following an air leak combined with high pressure oxygen ventilation in a patient with severe chronic obstructive pulmonary disease. The patient presented to our institution with diffuse coronary artery disease and angina pectoris. He was treated with coronary artery bypass graft surgery, including left internal thoracic artery harvesting. Additionally to this rare presentation of an intrathoracic fire, a brief review of surgical fires is included to this paper."],["dc.identifier.doi","10.1186/1749-8090-5-10"],["dc.identifier.isi","000275913300001"],["dc.identifier.pmid","20219127"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20350"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.title","Intrathoracic fire during preparation of the left internal thoracic artery for coronary artery bypass grafting"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","57"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Mokashi, Suyog A."],["dc.contributor.author","Emmert, Alexander"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Wiese, Christoph Hermann"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T08:40:27Z"],["dc.date.available","2018-11-07T08:40:27Z"],["dc.date.issued","2010"],["dc.description.abstract","We present a case of a 77-year old female who had undergone a coronary artery bypass grafting with an aortic valve replacement and developed three month later a Methicillin-Resistant Staphylococcus aureus (MRSA) sternal wound infection which was successful treated with Daptomycin combined with vacuum-assisted closure (VAC)."],["dc.identifier.doi","10.1186/1749-8090-5-57"],["dc.identifier.isi","000282338800001"],["dc.identifier.pmid","20691034"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19234"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.title","Daptomycin as a possible new treatment option for surgical management of Methicillin-Resistant Staphylococcus aureus sternal wound infection after cardiac surgery"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1103"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Artificial Organs"],["dc.bibliographiccitation.lastpage","1104"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Tempes, Tasso"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T08:50:09Z"],["dc.date.available","2018-11-07T08:50:09Z"],["dc.date.issued","2011"],["dc.description.abstract","Renal failure after open heart surgery is a serious complication even in the pediatric population. The aim of the present study was to analyze morphological changes after cardiopulmonary bypass (CPB) surgery in a neonatal piglet model. The kidneys of newborn piglets sacrificed 6 h after CPB were examined (CPB; n = 4) regarding tubular dilatation, vacuole formation, leukocytic infiltration, epithelial destruction, and interstitial edema. Thereafter, the findings were compared with the morphology of normal (untreated) neonatal piglet kidneys (control; n = 4). All changes but the interstitial edema were statistically significant if compared with the normal renal tissue: tubular dilatation (CPB vs. control P < 0.05), vacuole formation (CPB vs. control P < 0.05), leukocytic infiltration (CPB vs. control P < 0.05), and epithelial destruction (CPB vs. control P < 0.001). In conclusion, CPB induces significant changes in the morphology of the neonatal piglet kidneys."],["dc.identifier.doi","10.1111/j.1525-1594.2011.01364.x"],["dc.identifier.isi","000297201200017"],["dc.identifier.pmid","21973032"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21631"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0160-564X"],["dc.title","Cardiopulmonary Bypass and Its Direct Effects on Neonatal Piglet Kidney Morphology"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","JORS-D-20-00102R1"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Journal of Robotic Surgery"],["dc.bibliographiccitation.lastpage","9"],["dc.contributor.author","Leitsmann, Conrad"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Popeneciu, I. Valentin"],["dc.contributor.author","Boos, Margarete"],["dc.contributor.author","Ahyai, Sascha A."],["dc.contributor.author","Schmid, Marianne"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Friedrich, Martin"],["dc.date.accessioned","2021-06-01T10:49:20Z"],["dc.date.available","2021-06-01T10:49:20Z"],["dc.date.issued","2020"],["dc.description.abstract","To reduce noise pollution and consequently stress during robot-assisted laparoscopic radical prostatectomy (RALP) the aim of our study was to evaluate the silent operation theatre optimisation system (SOTOS) in its effectiveness. In the operating room (OR) the noise level is between 80 and 85 decibel (dB). Noise corresponds to a major stress factor for surgical teams and especially surgeons. The use of the da Vinci surgical system entails an additional aspect of noise in the OR. The SOTOS surgical team used wired or wireless headphone/microphone combinations to communicate. We measured sound pressure levels in two different locations in the OR and the heart rate of every surgical team member as an indicator of the stress level. We further captured subjective acceptance of SOTOS as well as perioperative data such as surgical time. We prospectively randomised 32 RALP patients into two study arms. Sixteen surgeries were performed using SOTOS and 16 without (con- trol). Overall, the mean sound pressure level in the SOTOS group was 3.6 dB lower compared to the control (p < 0.001). The highest sound pressure level measured was 96 dB in the control group. Mean heart rates were 81.3 beats/min for surgeons and 90.8 beats/min for circulating nurses. SOTOS had no statistically significant effect on mean heart rates of the operating team. Subjective acceptance of SOTO was high. Our prospective evaluation of SOTOS in RALP could show a significant noise reduction in the OR and a high acceptance by the surgical stuff."],["dc.identifier.doi","10.1007/s11701-020-01135-x"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86250"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1863-2491"],["dc.relation.issn","1863-2483"],["dc.title","The Silent Operation Theatre Optimisation System (SOTOS©) to reduce noise pollution during da Vinci robot-assisted laparoscopic radical prostatectomy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","969"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Artificial Organs"],["dc.bibliographiccitation.lastpage","979"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Heidrich, Florian"],["dc.contributor.author","Sossalla, Samuel T."],["dc.contributor.author","Schotola, Hanna"],["dc.contributor.author","Vorkamp, Tobias"],["dc.contributor.author","Ortmann, Philipp"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Rajab, Taufiek K."],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Hinz, Jose"],["dc.contributor.author","Bauer, Martin"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.date.accessioned","2018-11-07T08:37:19Z"],["dc.date.available","2018-11-07T08:37:19Z"],["dc.date.issued","2010"],["dc.description.abstract","We established a stable and reproducible animal model of chronic heart failure (CHF) in sheep to investigate biomolecular changes. Therefore, two biomarkers, adenosine monophosphate-activated protein kinase (AMPK) and vascular endothelial growth factor-A (VEGF-A) were examined to reveal their role during chronic ischemic conditions of the heart. AMPK was studied because it plays an important role in cellular energy homeostasis and its upregulation is associated with myocardial ischemia, whereas VEGF-A was studied because it acts as an important signaling protein for neoangiogenesis. We examined 15 juvenile sheep (mean weight, 78 +/- 4 kg; control, n = 3; ShamOP, n = 2; coronary microembolization [CME], n = 10). CHF was induced under fluoroscopic guidance by multiple sequential microembolizations (MEs) through bolus injection of polysterol microspheres (90 mu m, n = 25.000) into the left main coronary artery. CME was repeated up to three times at 2- to 3-week intervals until animals started to develop stable signs of CHF. All animals were followed for 3 months. Phosphorylation of AMPK, marking the activated protein form, was detected by Western blotting. VEGF-A and vascular endothelial growth factor-receptor 2 (VEGF-R2) mRNA were detected by real-time polymerase chain reaction. Glyceraldehyde-3-phosphate-dehydrogenase (GAPDH) was used as a reference housekeeping gene. All 10 CHF animals developed clinical signs of CHF as indicated by a significant decrease of cardiac output, decreased ejection fraction, as well as occurrence of tachycardia and tachypnoea. Western blots showed significant phosphorylation of AMPK in CME animals compared to the control group (phospho-adenosine monophosphate-activated protein kinase a) (GAPDH control: 0.0, CME left ventricle [LV]: 0.39 +/- 0.20, CME right ventricle [RV]: 0.53 +/- 0.30; P < 0.05). VEGF-A and VEGF-R2 expression in CME animal myocardium was within the range of the control group, but this data did not reach statistical significance due to the small size of this group. While microinjection was performed into the left main coronary artery, phosphorylation of AMPK and expression of VEGF-A and VEGF-R2 were significantly higher in the RV than in the LV. Multiple sequential intracoronary MEs can effectively induce myocardial dysfunction with clinical and biomolecular signs of chronic ischemic cardiomyopathy. Quantitative analysis of biomolecular markers showed a significantly higher phosphorylation of AMPK in CHF animals compared with control myocardium."],["dc.identifier.doi","10.1111/j.1525-1594.2010.01121.x"],["dc.identifier.isi","000284588300018"],["dc.identifier.pmid","21092039"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18501"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","6th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion"],["dc.relation.eventlocation","Boston, MA"],["dc.relation.issn","1525-1594"],["dc.relation.issn","0160-564X"],["dc.title","The Role of Phospho-Adenosine Monophosphate-Activated Protein Kinase and Vascular Endothelial Growth Factor in a Model of Chronic Heart Failure"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e95"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Pacing and Clinical Electrophysiology"],["dc.bibliographiccitation.lastpage","e97"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Rajaruthnam, Direndra"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T09:11:38Z"],["dc.date.available","2018-11-07T09:11:38Z"],["dc.date.issued","2012"],["dc.description.abstract","We describe a case of 83-year-old man who was admitted to our department for treatment of recurrent device-pocket infections. Our report shows that in a case of high-risk patient with a complicated cardiac implantable electric devices infection involving multidrug-resistent gram-positive pathogen, the application of daptomycin in combination with staged surgical therapy can be efficient and safe."],["dc.identifier.doi","10.1111/j.1540-8159.2011.03163.x"],["dc.identifier.isi","000302540300009"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26763"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0147-8389"],["dc.title","Treatment of Cardiovascular Implantable Electronic Device Infection with Daptomycin"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]