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Friedrich, Martin
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Friedrich, Martin
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Friedrich, Martin
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Friedrich, M. G.
Friedrich, Martin
Friedrich, M.
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2019-01Journal Article [["dc.bibliographiccitation.firstpage","58"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Perfusion"],["dc.bibliographiccitation.lastpage","66"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Budde, Holger"],["dc.contributor.author","Riggert, Joachim"],["dc.contributor.author","Vormfelde, Steffen"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Friedrich, Martin G."],["dc.date.accessioned","2020-12-10T18:38:24Z"],["dc.date.available","2020-12-10T18:38:24Z"],["dc.date.issued","2019-01"],["dc.description.abstract","Background: Re-transfusion of autologous blood is an important aspect of intraoperative blood management. Hemolysis and platelet dysfunction due to turbulence in the blood suction system strongly impede later usage of suction blood for re-transfusion. The aim of this study was to analyze the effects of a novel surgical-blood suction system with an automatic control setup for minimization of turbulence in the blood flow. Methods: We compared the turbulence-controlled suction system (TCSS) with a conventional suction system and untreated control blood in vitro. Blood cell counts, hemolysis levels according to free hemoglobin (fHb) and platelet function were analyzed to determine the integrity of the suction blood. Results: In the conventional suction system, we found a strong increase of the fHb levels. In contrast, erythrocyte integrity was almost completely preserved when using the TCSS. We obtained similar results regarding platelet function. The expression of platelet glycoproteins, such as GP IIb/IIIa and P-selectin, native or after stimulation with ADP, were markedly impaired by the conventional system, but not by the TCSS. In addition, platelet aggregometry revealed significant platelet dysfunction in conventional suction blood, but less aggregation impairments were present in blood samples from the TCSS. Conclusion: Our findings on an in vitro assessment show major improvements in red blood cell integrity and platelet function of suction blood when using the TCSS compared to a conventional suction system. These results reflect a significant benefit for autologous re-transfusion. We suggest testing the TCSS in surgery for clinical evaluation."],["dc.identifier.doi","10.1177/0267659118790915"],["dc.identifier.eissn","1477-111X"],["dc.identifier.issn","0267-6591"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77305"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.publisher","SAGE Publications"],["dc.relation.eissn","1477-111X"],["dc.relation.issn","0267-6591"],["dc.title","The effect of a novel turbulence-controlled suction system in the prevention of hemolysis and platelet dysfunction in autologous surgery blood"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2020Journal Article [["dc.bibliographiccitation.firstpage","E174"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The Heart Surgery Forum"],["dc.bibliographiccitation.lastpage","E177"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Bougioukas, Ioannis G."],["dc.contributor.author","Friedrich, Martin G."],["dc.contributor.author","Danner, Bernhard C."],["dc.contributor.author","Schoendube, Friedrich A."],["dc.date.accessioned","2020-12-10T18:42:40Z"],["dc.date.available","2020-12-10T18:42:40Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1532/hsf.2893"],["dc.identifier.eissn","1522-6662"],["dc.identifier.issn","1098-3511"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17343"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78041"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Re-exploration Early after Cardiac Surgery in Adults: The Importance of Bleeding-Related Complications"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI2013Journal Article [["dc.bibliographiccitation.firstpage","502"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Vascular and Endovascular Surgery"],["dc.bibliographiccitation.lastpage","506"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Danner, Bernhard Christoph"],["dc.contributor.author","Bougioukas, Ioannis"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Stojanovic, Tomislav"],["dc.date.accessioned","2018-11-07T09:19:26Z"],["dc.date.available","2018-11-07T09:19:26Z"],["dc.date.issued","2013"],["dc.description.abstract","Objective: We conducted a retrospective study to compare short- and mid-term patencies of Viabahn with surgical above-knee prosthetic bypass (pAKB). Methods: The records of 52 patients with either pAKB (n = 25) or Viabahn (n = 27) were reviewed. The majority had Rutherford clinical grade 3. Patients were followed after 3, 6, and 12 months and yearly thereafter. Results: For Viabahn, the short-term (1-16 months) primary patency rate was 60% with a secondary patency rate of 90%, and mid-term (1-68 months) patencies of 47% and 83.3%, respectively. In pAKB, the short-term results revealed a primary patency rate of 78% with a secondary patency of 91% and mid-term results of 65% and 90%, respectively. No statistical difference was found concerning short-term patencies. Mid-term primary patency was lower for Viabahn (P < .05) and secondary patency proved no significant difference. Conclusion: Viabahn revealed similar short-term primary and secondary patencies but lower mid-term primary patency. It provides a good alternative therapy to pAKB."],["dc.identifier.doi","10.1177/1538574413495964"],["dc.identifier.isi","000324591400002"],["dc.identifier.pmid","23867203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28635"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Inc"],["dc.relation.issn","1938-9116"],["dc.relation.issn","1538-5744"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Is There an Alternative to the Surgical Above-Knee Bypass in Treatment of Superficial Femoral Artery Disease? Experiences With Viabahn Stent Graft"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2017-01-25Journal Article [["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Bougioukas, Ioannis"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Grossmann, Marius"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Schoendube, Friedrich A."],["dc.contributor.author","Danner, Bernhard Christoph"],["dc.date.accessioned","2018-10-10T09:54:39Z"],["dc.date.available","2018-10-10T09:54:39Z"],["dc.date.issued","2017-01-25"],["dc.description.abstract","Re-exploration for bleeding accounts for increased morbidity and mortality after major cardiac operations. The use of temporary epicardial pacemaker wires is a common procedure at many departments. The removal of these wires postoperatively can potentially lead to a serious bleeding necessitating intervention. From Jan 2011 till Dec 2015 a total of 4244 major cardiac procedures were carried out at our department. We used temporary epicardial pacemaker wires in all cases. We collected all re-explorations for bleeding and pericardial tamponade from our surgical database and then we focused on the late re-explorations, meaning on the 4th postoperative day and thereafter, trying to identify the removal of the temporary pacemakerwires as the definite cause of bleeding. Patients’ records and medication were examined. Thirty-nine late re-explorations for bleeding, consisting of repeat sternotomies, thoracotomies and subxiphoid pericardial drainages, were gathered. Eight patients had an acute bleeding incidence after removal ofthe temporary wires (0.18%). In four of these patients, a pericardial drainage was inserted, whereas the remaining patients were re-explorated through a repeat sternotomy. Two patients died of the acute pericardial tamponade,three had a blood transfusion and one had a wound infection. Seven out of eight patients were either on dualantiplatelet therapy or on combination of aspirin and vitamin K antagonist. A need for re-exploration due to removal of the temporary pacemaker wires is a very rare complication, which however increases morbidity and mortality. Adjustment of the postoperative anticoagulation therapy at the time of removal of the wires could further minimize or even prevent this serious complication."],["dc.identifier.doi","10.1186/s13019-017-0569-5"],["dc.identifier.gro","633982"],["dc.identifier.pmid","28122567"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14188"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15938"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.eissn","1749-8090"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Is there a correlation between late re-exploration after cardiac surgery and removal of epicardial pacemaker wires?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC2010Journal Article [["dc.bibliographiccitation.artnumber","12"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Ortmann, Philipp"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Schotola, Hanna"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Wiese, Christoph Hermann"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Mokashi, Suyog A."],["dc.contributor.author","Didilis, Vassilios N."],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T08:45:01Z"],["dc.date.available","2018-11-07T08:45:01Z"],["dc.date.issued","2010"],["dc.description.abstract","We report a case of a male patient who received an implantation of a Starr-Edwards-caged-ball-valve-prosthesis in 1967. The surgery and postoperative course were without complications and the patient recovered well after the operation. For the next four decades, the patient remained asymptomatic - no restrictions on his lifestyle and without any complications. In 2006, 39 years after the initial operation, we performed a Bentall-Procedure to treat an aortic ascendens aneurysm with diameters of 6.0 x 6.5 cm: we explanted the old Starr-Edwards-aortic-caged-ball-valve-prosthesis and replaced the ascending aorta with a 29 mm St. Jude Medical aortic-valve-composite-graft and re-implanted the coronary arteries. This case represents the longest time period between Starr-Edwards-caged-ball-valve-prothesis-implantation and Bentall-reoperation, thereby confirming the excellent durability of this valve."],["dc.identifier.doi","10.1186/1749-8090-5-12"],["dc.identifier.isi","000276399500001"],["dc.identifier.pmid","20298579"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/5687"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20331"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Bentall procedure 39 years after implantation of a Starr-Edwards Aortic Caged- Ball-Valve Prosthesis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2015Journal Article [["dc.bibliographiccitation.firstpage","339"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Journal of Medical Cases"],["dc.bibliographiccitation.lastpage","341"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Emmert, Alexander"],["dc.contributor.author","Robert, Franke"],["dc.contributor.author","Bohnenberger, Hanibal"],["dc.contributor.author","Sahlmann, Carsten-Oliver"],["dc.contributor.author","Schondube, Friedrich A."],["dc.contributor.author","Egan, Michael"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Danner, Bernhard C."],["dc.contributor.author","Hinterthaner, Marc"],["dc.date.accessioned","2019-07-09T11:41:24Z"],["dc.date.available","2019-07-09T11:41:24Z"],["dc.date.issued","2015"],["dc.description.abstract","Isolated mediastinal Kocuria rosea infection is a rare condition and presentation can be variable. We report an unusual case of Kocuria rosea infection which presented as solitary pulmonary nodules and isolated lymph node swelling, entirely confined within the tracheal bifurcation and 18-fluoredeoxyglucose position emission tomography and computed tomography (18FDG PET/CT)-avid, thereby mimicking a neoplastic lesion. Owing to the large differential diagnosis, which includes diseases such as pulmonary neoplasia and lymph node metastases, a biopsy via mediastinoscopy was to be attempted, so hopefully avoiding thoracotomy. Histopathology analysis of the resected mediastinal lymph nodes (MLNs) demonstrated no malignant cells, but rather necrotizing MLNs, which is classically associated with Kocuria rosea infection. The patient was asymptomatic and biopsy allowed a precise diagnosis. Kocuria rosea infection is rare; it should be considered when FDG PET shows intense FDG uptake in non-regionally swollen lymph nodes."],["dc.identifier.doi","10.14740/jmc2122w"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12016"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58420"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1923-4163"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Isolated Mediastinal Kocuria rosea Infection Mimicking Malignancies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI2011Journal Article [["dc.bibliographiccitation.artnumber","112"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Jebran, Ahmad Fawad"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Rajaruthnam, Direndra"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Hinz, Jose"],["dc.contributor.author","Tirilomis, Theodor"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T08:51:42Z"],["dc.date.available","2018-11-07T08:51:42Z"],["dc.date.issued","2011"],["dc.description.abstract","The reported incidence of deep sternal wound infection (DSWI) after cardiac surgery is 0.4-5% with Staphylococcus aureus being the most common pathogen isolated from infected wound sternotomies and bacteraemic blood cultures. This infection is associated with a higher morbidity and mortality than other known aetiologies. Little is reported about the optimal antibiotic management. The aim of the study is to quantify the application of daptomycin treatment of DSWI due to gram-positive organisms post cardiac surgery. We performed an observational analysis in 23 cases of post sternotomy DSWI with gram-positive organisms February 2009 and September 2010. When the wound appeared viable and the microbiological cultures were negative, the technique of chest closure was individualised to the patient. The incidence of DSWI was 1.46%. The mean dose of daptomycin application was 4.4 +/- 0.9 mg/kg/d and the average duration of the daptomycin application was 14.47 +/- 7.33 days. In 89% of the patients VAC therapy was used. The duration from daptomycin application to sternal closure was 18 +/- 13.9 days. The parameters of infection including, fibrinogen (p = 0.03), white blood cell count (p = 0.001) and C-reactive protein (p = 0.0001) were significantly reduced after daptomycin application. We had no mortality and wound healing was successfully achieved in all patients. Treatment of DSWI due to gram-positive organisms with a daptomycin-containing antibiotic regimen is safe, effective and promotes immediate improvement of local wound conditions. Based on these observations, daptomycin may offer a new treatment option for expediting surgical management of DSWI after cardiac surgery."],["dc.identifier.doi","10.1186/1749-8090-6-112"],["dc.identifier.isi","000295483400002"],["dc.identifier.pmid","21929771"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6983"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21999"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Treatment of gram-positive deep sternal wound infections in cardiac surgery -experiences with daptomycin-"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2011Journal Article [["dc.bibliographiccitation.artnumber","12"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Schotola, Hanna"],["dc.contributor.author","Trethowan, Brian"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","El-Mehsen, Mohamed"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.contributor.author","Tirilomis, Theodor"],["dc.date.accessioned","2018-11-07T08:59:19Z"],["dc.date.available","2018-11-07T08:59:19Z"],["dc.date.issued","2011"],["dc.description.abstract","We report a case of a female patient who was operated at the third relapse of an atrial myxoma caused by Carney complex. The difficult operation was performed without any complications despite extensive adhesions caused by the previous operations. The further inpatient course went without complications and the patient was discharged to the consecutive treatment on the 9th postoperative day. The echocardiographic finding postoperative showed no abnormalities."],["dc.identifier.doi","10.1186/1749-8090-6-12"],["dc.identifier.fs","577749"],["dc.identifier.isi","000287353500001"],["dc.identifier.pmid","21291531"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/5887"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23862"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.rights","CC BY 2.0"],["dc.rights.access","openAccess"],["dc.rights.holder","Bireta et al.; licensee BioMed Central Ltd."],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.subject.ddc","610"],["dc.title","Carney-Complex: Multiple resections of recurrent cardiac myxoma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2009Journal Article [["dc.bibliographiccitation.artnumber","51"],["dc.bibliographiccitation.journal","Journal of Cardiothoracic Surgery"],["dc.bibliographiccitation.volume","4"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Bireta, Christian"],["dc.contributor.author","Schmitto, Jan Dieter"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Friedrich, Martin"],["dc.contributor.author","Coskun, Kasim Oguz"],["dc.contributor.author","Seipelt, Ralf G."],["dc.contributor.author","Hanekop, Gerd-Gunnar"],["dc.contributor.author","Schoendube, Friedrich Albert"],["dc.date.accessioned","2018-11-07T11:24:14Z"],["dc.date.available","2018-11-07T11:24:14Z"],["dc.date.issued","2009"],["dc.description.abstract","We report an unusual case of a 32-year old man who was treated for a hypertrophic obstructive cardiomyopathy (HOCM) with a DDD pacing with short AV delay reduction in the past. Without prior notice the patient developed ventricular fibrillation and an invasive cardiac diagnostic was performed, which revealed a myocardial bridging around of the left anterior descending artery (LAD). We suspected ischemia that could be either related to LAD artery compression or perfusion abnormalities due to AV delay reduction with related to diastolic dysfunction."],["dc.identifier.doi","10.1186/1749-8090-4-51"],["dc.identifier.isi","000270928200002"],["dc.identifier.pmid","19761610"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/5746"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56357"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1749-8090"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Myocardial ischemia with left ventricular outflow obstruction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2018Journal Article [["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Surgery Research and Practice"],["dc.bibliographiccitation.lastpage","8"],["dc.bibliographiccitation.volume","2018"],["dc.contributor.author","Friedrich, M. G."],["dc.contributor.author","Tirilomis, T."],["dc.contributor.author","Kollmeier, J. M."],["dc.contributor.author","Wang, Y."],["dc.contributor.author","Hanekop, G. G."],["dc.date.accessioned","2019-07-09T11:49:36Z"],["dc.date.available","2019-07-09T11:49:36Z"],["dc.date.issued","2018"],["dc.description.abstract","Introduction. Suction devices for clearing the surgical field are among the most commonly used tools of every surgeon because a better view of the surgical field is essential. Forced suction may produce disturbingly loud noise, which acts as a nonnegligible stressor. Especially, in emergency situations with heavy bleeding, this loud noise has been described as an impeding factor in the medical decision-making process. In addition, there are reports of inner ear damage in patients due to suction noises during operations in the head area. These problems have not been solved yet. The purpose of this study was to analyse flow-dependent suction noise effects of different surgical suction tips. Furthermore, we developed design improvements to these devices. Methods. We compared five different geometries of suction tips using an in vitro standardised setup. Two commercially available standard suction tips were compared to three adapted new devices regarding their flow-dependent (10–2000 mL/min) noise emission (dB, weighting filter (A), distance 10 cm) and acoustic quality of resulting noises (Hamilton fast Fourier analysis) during active suction at the liquid-air boundary. Noise maps at different flow rates were created for all five suction devices, and the proportion of extracted air was measured. The geometries of the three custom-made suction tips (new models 1, 2, and 3) were designed considering the insights after determining the key characteristics of the two standard suction models. Results. The geometry of a suction device tip has significant impact on its noise emission. For the standard models, the frequency spectrum at higher flow rates significantly changes to high-frequency noise patterns (>3 kHz). A number of small side holes designed to prevent tissue adhesion lead to increased levels of high-frequency noise. Due to modifications of the tip geometry in our new models, we are able to achieve a highly significant reduction of noise level at low flow rates (new model 2 vs. standard models ) and also the acoustic quality improved. Additionally, we attain a highly significant reduction of secondary air intake (new model 2 vs. the other models ). Conclusion. Improving flow-relevant features of the geometry of suction heads is a suitable way to reduce noise emissions. Optimized suction tips are significantly quieter. This may help us to reduce noise-induced hearing damage in patients as well as stress of medical staff during surgery and should lead to quieter operation theatres overall. Furthermore, the turbulence reduction and reduced secondary air intake during the suction process are expected to result in protective effects on the collected blood and thus could improve the quality of autologous blood retransfusions. We are on the way to evaluate potential benefits."],["dc.identifier.doi","10.1155/2018/3074819"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15721"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59588"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Modifications of Surgical Suction Tip Geometry for Flow Optimisation: Influence on Suction-Induced Noise Pollution"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]Details DOI