Emmert, Steffen

[["dc.bibliographiccitation.firstpage","278"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Plasma Processes and Polymers"],["dc.bibliographiccitation.lastpage","286"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Helmke, Andreas"],["dc.contributor.author","Hoffmeister, Dennis"],["dc.contributor.author","Berge, Frank"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Laspe, Petra"],["dc.contributor.author","Mertens, Nina"],["dc.contributor.author","Vioel, Wolfgang"],["dc.contributor.author","Weltmann, Klaus-Dieter"],["dc.date.accessioned","2018-11-07T08:56:58Z"],["dc.date.available","2018-11-07T08:56:58Z"],["dc.date.issued","2011"],["dc.description.abstract","The inactivation of the Gram-positive bacteria Staphylococcus epidermidis (ATCC 12228) in its vegetative state was studied in vitro after exposure to cold atmospheric pressure plasma generated by direct dielectric barrier discharge (DBD). Compared to UV radiation at 254 nm, plasma UV emission yielded no significant contribution to bacterial inactivation. Analysis of bacterial growth inhibition revealed a pH dependency on growth media. Yet, measurements combined with numerical simulations excluded the pH shift induced by plasma generated reactive species as the main cause of bacterial inactivation. Scanning electron microscopy (SEM) images showed no alteration of cell walls, while fluorescence microscopy revealed lethal damage to cell membranes even after 1 s treatment. When the cell membrane was already severely damaged, also degradation of the bacterial DNA by plasma treatment was found. We conclude that membrane damage due to reactive oxygen species (ROS) and DNA degradation are the main mechanisms of plasma-induced bacterial death that is aggregated by milieu acidification."],["dc.identifier.doi","10.1002/ppap.201000168"],["dc.identifier.isi","000289999200001"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23275"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-v C H Verlag Gmbh"],["dc.relation.issn","1612-8869"],["dc.relation.issn","1612-8850"],["dc.title","Physical and Microbiological Characterisation of Staphylococcus epidermidis Inactivation by Dielectric Barrier Discharge Plasma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","165201"],["dc.bibliographiccitation.issue","16"],["dc.bibliographiccitation.journal","Journal of Physics D Applied Physics"],["dc.bibliographiccitation.volume","46"],["dc.contributor.author","Hirschberg, Joanna"],["dc.contributor.author","Omairi, Tarek"],["dc.contributor.author","Mertens, Nina"],["dc.contributor.author","Helmke, Andreas"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Vioel, Wolfgang"],["dc.date.accessioned","2018-11-07T09:25:54Z"],["dc.date.available","2018-11-07T09:25:54Z"],["dc.date.issued","2013"],["dc.description.abstract","Two dielectric barrier discharges created in atmospheric pressure air were compared to investigate influences of excitation pulse duration on plasma parameters. A plasma source with a pulsed excitation and pulse durations in the mu s range as well as a source with pulse durations in the ns range were investigated. An aluminum plate with skin lipids of the stratum corneum on the one hand and an aluminum needle without lipids for operating in the single filamentary mode on the other hand were used as opposite electrodes. The optical emission spectroscopy was arranged to determine the rotational and vibrational temperatures by comparing experimental with simulated spectra. Vibrational temperatures were calculated in a range 2200-2600 K, rotational temperatures were measured from 300 up to 600 K. In addition, the electron temperatures (7-15 eV) and the reduced electric fields (280-800 Td) were estimated. Electric parameters were detected by both current and voltage measurements with a resulting range 200-500 mW of dissipated power."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft [Ma 1893/20]"],["dc.identifier.doi","10.1088/0022-3727/46/16/165201"],["dc.identifier.isi","000317035200012"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30170"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Iop Publishing Ltd"],["dc.relation.issn","1361-6463"],["dc.relation.issn","0022-3727"],["dc.title","Influence of excitation pulse duration of dielectric barrier discharges on biomedical applications"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","910"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Plasma Processes and Polymers"],["dc.bibliographiccitation.lastpage","920"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Mertens, Nina"],["dc.contributor.author","Mahmoodzada, Mostafa"],["dc.contributor.author","Helmke, Andreas"],["dc.contributor.author","Gruenig, Petra"],["dc.contributor.author","Laspe, Petra"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Vioel, Wolfgang"],["dc.date.accessioned","2018-11-07T09:34:06Z"],["dc.date.available","2018-11-07T09:34:06Z"],["dc.date.issued","2014"],["dc.description.abstract","The effect of CAP on the dermatologic relevant bacteria E. coli, P. aeruginosa and the yeast C. albicans is studied in vitro. Two dielectric barrier discharge plasma devices with different temporal pulse characteristics are compared concerning their efficacy of germ inactivation. The study includes analyses of temperature, ozone concentration and UV radiation in the discharge gap as well as the influence on the growth medium in terms of temperature, pH value, NO2-, NO3-, and H2O2. The investigations are concluded by tests of growth inhibition, the morphological structure, and DNA damages of the microorganisms. The results demonstrate, that both devices are able to inactivate the germs, although the nanosecond pulsed plasma source has a higher efficacy based on a higher chemical discharge productivity."],["dc.identifier.doi","10.1002/ppap.201300184"],["dc.identifier.isi","000344180900001"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32106"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-v C H Verlag Gmbh"],["dc.relation.issn","1612-8869"],["dc.relation.issn","1612-8850"],["dc.title","Inactivation of Microorganisms Using Cold Atmospheric Pressure Plasma with Different Temporal Discharge Characteristics"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","24"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Clinical Plasma Medicine"],["dc.bibliographiccitation.lastpage","29"],["dc.bibliographiccitation.volume","1"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Hänßle, Holger"],["dc.contributor.author","Helmke, Andreas"],["dc.contributor.author","Mertens, Nina"],["dc.contributor.author","Ahmed, Raees"],["dc.contributor.author","Simon, Dirk"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Maus-Friedrichs, Wolfgang"],["dc.contributor.author","Däschlein, Georg"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Viöl, Wolfgang"],["dc.date.accessioned","2019-02-19T13:45:08Z"],["dc.date.available","2019-02-19T13:45:08Z"],["dc.date.issued","2013"],["dc.description.abstract","Plasma in the sense of ionized gas can be referred to as the fourth state of matter following solids, liquids, and gases in view of their energy content. Application of high voltages across small gas filled spaces results in ionization of the air. Generally, two types of cold plasma can be discerned: direct plasma (e.g. dielectric barrier discharge—DBD) and indirect plasma (plasma torch, plasma jet). In indirect plasma treatment, the plasma is produced in a remote cavity and ejected by gas flow onto the skin in the form of an effluent. In direct plasma treatment, the skin itself acts as the counter electrode. Advantageous features of direct plasma treatment include the higher plasma density as well as the induced high frequency electric current onto the skin. In plasma treatment antiinflammatory, antipruritic, antimicrobial, tissue stimulation, stimulation of microcirculation, and other therapeutic effects are achieved in a single treatment due to the combined action of ultraviolet radiation, reactive oxygen species (e.g. ozone), reactive nitrogen species, and electric fields. In line with other reports, we have already demonstrated the use of direct plasma treatment in skin disinfection, in atopic eczema (superinfected dermatitis), in modulating the epidermal barrier, as well as in chronic wound treatment. We as well as others did not notice any side effects of plasma treatment so far. In summary, cold atmospheric pressure plasma constitutes a new and innovative treatment option especially for superinfected skin diseases. These promising relatively new clinical applications warrant further carefully conducted translational research to delineate the modes of actions of plasma as well as potential long term side effects. This should lead to norms for the technical devices to allow a standardized treatment of given diseases in the mid-term."],["dc.identifier.doi","10.1016/j.cpme.2012.11.002"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/57585"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.title","Atmospheric pressure plasma in dermatology: Ulcus treatment and much more"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]