Emmert, Steffen

[["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Richter, A."],["dc.contributor.author","Haas, E."],["dc.contributor.author","Holzkamp, R."],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.date.accessioned","2018-11-07T08:52:36Z"],["dc.date.available","2018-11-07T08:52:36Z"],["dc.date.issued","2011"],["dc.format.extent","781"],["dc.identifier.isi","000294596900143"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22210"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Malden"],["dc.relation.issn","1610-0379"],["dc.title","Radiotherapy in thyroid Eye Disease: Ocurrence of pigmented Basal Cell Carcinomas with 15 years Latency"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Hofmann, L."],["dc.contributor.author","Brauns, B."],["dc.contributor.author","Kraus, S."],["dc.contributor.author","Wolff, Christian"],["dc.contributor.author","Thoms, K-M"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Kretschmer, Lutz"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.date.accessioned","2018-11-07T09:20:50Z"],["dc.date.available","2018-11-07T09:20:50Z"],["dc.date.issued","2013"],["dc.format.extent","927"],["dc.identifier.isi","000323202300082"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28966"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0379"],["dc.title","The in vivo confocal Laser-scanning Microscopy increases the pre-operative diagnostic Accuracy in cutaneous Neoplasia"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Daeschlein, G."],["dc.contributor.author","Ahmed, R."],["dc.contributor.author","Pfeiffer, S."],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Simon, D."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T09:19:10Z"],["dc.date.available","2018-11-07T09:19:10Z"],["dc.date.issued","2013"],["dc.format.extent","10"],["dc.identifier.isi","000324332500029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28574"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","The Treatment of chronic venous Leg Ulcers with direct Plasma (PlasmaDerm (R) VU 2010): Results of a single center, two-arm, open-label, randomized, controlled Trial"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Hoffmann, S."],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Rosenberger, Albert"],["dc.date.accessioned","2018-11-07T09:36:15Z"],["dc.date.available","2018-11-07T09:36:15Z"],["dc.date.issued","2014"],["dc.format.extent","15"],["dc.identifier.isi","000340532500037"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32571"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Determination of Patient Characteristics in Specific Melanoma Subtypes by means of a Prospective Observational Study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","486"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.lastpage","489"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Schaefer, Annika"],["dc.contributor.author","Gratchev, Alexei"],["dc.contributor.author","Seebode, Christina"],["dc.contributor.author","Hofmann, Lars"],["dc.contributor.author","Schubert, Steffen"],["dc.contributor.author","Laspe, Petra"],["dc.contributor.author","Apel, Antje"],["dc.contributor.author","Ohlenbusch, Andreas"],["dc.contributor.author","Tzvetkov, Mladen"],["dc.contributor.author","Weishaupt, Carsten"],["dc.contributor.author","Oji, Vinzenz"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T09:23:16Z"],["dc.date.available","2018-11-07T09:23:16Z"],["dc.date.issued","2013"],["dc.description.abstract","The xeroderma pigmentosum (XP) group D protein is involved in nucleotide excision repair (NER) as well as in basal transcription. Determined by the type of XPD mutation, six different clinical entities have been distinguished: XP, XP with neurological symptoms, trichothiodystrophy (TTD), XP/TTD complex, XP/Cockayne syndrome (CS) complex or the cerebro-oculo-facio-skeletal syndrome (COFS). We identified nine new XPD-deficient patients. Their fibroblasts showed reduced post-UV cell survival, reduced NER capacity, normal XPD mRNA expression and partly reduced XPD protein expression. Six patients exhibited a XP phenotype in accordance with established XP-causing mutations (c.2079G>A, p.R683Q; c.2078G>T, p.R683W; c.1833G>T, p.R601L; c.1878G>C, p.R616P; c.1878G>A, p.R616Q). One TTD patient was homozygous for the known TTD-causing mutation p.R722W (c.2195C>T). Two patients were compound heterozygous for a TTD-causing mutation (c.366G>A, p.R112H) and a novel p.D681H (c.2072G>C) amino acid exchange, but exhibited different TTD and XP/CS complex phenotypes, respectively. Interestingly, the XP/CS patient's cells exhibited a reduced but well detectable XPD protein expression compared with hardly detectable XPD expression of the TTD patient's cells. Same mutations with different clinical outcomes in NER-defective patients demonstrate the complexity of phenotype-genotype correlations, for example relating to additional genetic variations (parental consanguinity), different allelic expression due to SNPs or differences in the methylation status."],["dc.identifier.doi","10.1111/exd.12166"],["dc.identifier.isi","000320935600012"],["dc.identifier.pmid","23800062"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29540"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1600-0625"],["dc.relation.issn","0906-6705"],["dc.title","Functional and molecular genetic analyses of nine newly identified XPD-deficient patients reveal a novel mutation resulting in TTD as well as in XP/CS complex phenotypes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","37"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","45"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Hoffmann, Saskia"],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Bertsch, Hans Peter"],["dc.contributor.author","Rosenberger, Albert"],["dc.date.accessioned","2018-11-07T10:04:00Z"],["dc.date.available","2018-11-07T10:04:00Z"],["dc.date.issued","2015"],["dc.description.abstract","BackgroundCertain melanoma histotypes carry a worse prognosis than others. We aimed to identify patient related factors associated with specific melanoma histotypes. Patients and methodsSingle center study including 347 melanoma patients, prospectively assessed for 22 variables leading to a database of more than 7600 features. ResultsMelanomas were histologically categorized as superficial spreading (SSM, 70.6%), nodular (NM; 12.7%), acrolentiginous (ALM; 4.0%), lentigo maligna (LMM; 3.8%), or unclassified melanoma (UCM; 8.9%). Well recognized melanoma risk indicators (i.e. many atypical nevi, freckles, previous melanoma), were significantly associated with SSM and LMM histotypes. NM and ALM patients carried significantly less common and/or atypical nevi. NM were mostly self-detected or detected by relatives. In contrast, SSM, LMM, and ALM were most frequently detected by dermatologists. NM and UCM were preferentially located on poorly observable sites, SSM on the lower limbs, ALM on plantar sites, and LMM on the head and neck. ALM and LMM patients were significantly older than other patients. A multinomial logistic model was designed to predict a certain melanoma histotype (overall accuracy 81%), which could be helpful to focus the attention of clinicians or may be integrated into fully automated diagnostic algorithms. ConclusionsMelanoma histotypes show significant differences regarding patients' characteristics."],["dc.identifier.doi","10.1111/ddg.12561"],["dc.identifier.isi","000347445900006"],["dc.identifier.pmid","25640492"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38598"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Assessment of melanoma histotypes and associated patient related factors: Basis for a predictive statistical model"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Hansen-Hagge, Christian"],["dc.contributor.author","Korpas, Bianca"],["dc.contributor.author","Kaune, Kjell Matthias"],["dc.contributor.author","Rosenberger, Albert"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, M."],["dc.date.accessioned","2018-11-07T08:52:36Z"],["dc.date.available","2018-11-07T08:52:36Z"],["dc.date.issued","2011"],["dc.format.extent","766"],["dc.identifier.isi","000294596900091"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22209"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Malden"],["dc.relation.issn","1610-0379"],["dc.title","Melanoma Early Detction with the Algorithm DynaMel: Combined dermatoscopic dynamic Evaluation and static Criteria"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Daeschlein, G."],["dc.contributor.author","Ahmed, R."],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Simon, D."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T09:27:22Z"],["dc.date.available","2018-11-07T09:27:22Z"],["dc.date.issued","2013"],["dc.format.extent","E11"],["dc.identifier.isi","000316332000063"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30517"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","40th Annual Meeting of the Association-of-Dermatological-Research"],["dc.relation.eventlocation","Dessau, GERMANY"],["dc.relation.issn","0906-6705"],["dc.title","Treatment of chronic venous leg ulcers with a hand-held DBD plasma generator (PlasmaDerm (R) VU-2010): results of a monocentric, two-armed, open, randomized, and controlled trial (NCT01415622)"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","791"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","792"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Schaefer, A."],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Kruppa, Jochen"],["dc.contributor.author","Schubert, S."],["dc.contributor.author","Tzvetkov, Mladen Vassilev"],["dc.contributor.author","Moessner, R."],["dc.contributor.author","Reich, Kristian"],["dc.contributor.author","Berking, Carola"],["dc.contributor.author","Volkenandt, Matthias"],["dc.contributor.author","Pfoehler, Claudia"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Vogt, T."],["dc.contributor.author","Koenig, Inke R."],["dc.contributor.author","Reichrath, Joerg"],["dc.date.accessioned","2018-11-07T08:52:36Z"],["dc.date.available","2018-11-07T08:52:36Z"],["dc.date.issued","2011"],["dc.identifier.isi","000294596900179"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22212"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Malden"],["dc.relation.issn","1610-0379"],["dc.title","No Associateion of Polymorphisms in Genes of the Vitamin D Metabolism and the Risk of Melanoma Development and Melanoma Prognosis: a Case-Control Study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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