Hartmann, Franziska

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Daeschlein, G."],["dc.contributor.author","Ahmed, R."],["dc.contributor.author","Pfeiffer, S."],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Simon, D."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T09:19:10Z"],["dc.date.available","2018-11-07T09:19:10Z"],["dc.date.issued","2013"],["dc.format.extent","10"],["dc.identifier.isi","000324332500029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28574"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","The Treatment of chronic venous Leg Ulcers with direct Plasma (PlasmaDerm (R) VU 2010): Results of a single center, two-arm, open-label, randomized, controlled Trial"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Daeschlein, G."],["dc.contributor.author","Ahmed, R."],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Simon, D."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T09:27:22Z"],["dc.date.available","2018-11-07T09:27:22Z"],["dc.date.issued","2013"],["dc.format.extent","E11"],["dc.identifier.isi","000316332000063"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30517"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","40th Annual Meeting of the Association-of-Dermatological-Research"],["dc.relation.eventlocation","Dessau, GERMANY"],["dc.relation.issn","0906-6705"],["dc.title","Treatment of chronic venous leg ulcers with a hand-held DBD plasma generator (PlasmaDerm (R) VU-2010): results of a monocentric, two-armed, open, randomized, and controlled trial (NCT01415622)"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","946"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Der Hautarzt"],["dc.bibliographiccitation.lastpage","948"],["dc.bibliographiccitation.volume","64"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Hofmann, L."],["dc.contributor.author","Wolff, Christian"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Brauns, B."],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.date.accessioned","2018-11-07T09:17:00Z"],["dc.date.available","2018-11-07T09:17:00Z"],["dc.date.issued","2013"],["dc.identifier.doi","10.1007/s00105-013-2669-z"],["dc.identifier.isi","000328492200016"],["dc.identifier.pmid","24337309"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28062"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-1173"],["dc.relation.issn","0017-8470"],["dc.title","Brown Macule with parallel Ridge Pattern on the Palm of a 58-Year-old Woman"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","148"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of the European Academy of Dermatology and Venereology"],["dc.bibliographiccitation.lastpage","155"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Daeschlein, G."],["dc.contributor.author","Ahmed, R."],["dc.contributor.author","Pfeiffer, S."],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Simon, D."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T10:04:03Z"],["dc.date.available","2018-11-07T10:04:03Z"],["dc.date.issued","2015"],["dc.description.abstract","BackgroundCold atmospheric plasma (CAP, i.e. ionized air) is an innovating promising tool in reducing bacteria. ObjectiveWe conducted the first clinical trial with the novel PlasmaDerm((R)) VU-2010 device to assess safety and, as secondary endpoints, efficacy and applicability of 45s/cm(2) cold atmospheric plasma as add-on therapy against chronic venous leg ulcers. MethodsFrom April 2011 to April 2012, 14 patients were randomized to receive standardized modern wound care (n=7) or plasma in addition to standard care (n=7) 3x per week for 8weeks. The ulcer size was determined weekly (Visitrak((R)), photodocumentation). Bacterial load (bacterial swabs, contact agar plates) and pain during and between treatments (visual analogue scales) were assessed. Patients and doctors rated the applicability of plasma (questionnaires). ResultsThe plasma treatment was safe with 2 SAEs and 77 AEs approximately equally distributed among both groups (P=0.77 and P=1.0, Fisher's exact test). Two AEs probably related to plasma. Plasma treatment resulted in a significant reduction in lesional bacterial load (P=0.04, Wilcoxon signed-rank test). A more than 50% ulcer size reduction was noted in 5/7 and 4/7 patients in the standard and plasma groups, respectively, and a greater size reduction occurred in the plasma group (plasma -5.3cm(2), standard: -3.4cm(2)) (non-significant, P=0.42, log-rank test). The only ulcer that closed after 7weeks received plasma. Patients in the plasma group quoted less pain compared to the control group. The plasma applicability was not rated inferior to standard wound care (P=0.94, Wilcoxon-Mann-Whitney test). Physicians would recommend (P=0.06, Wilcoxon-Mann-Whitney test) or repeat (P=0.08, Wilcoxon-Mann-Whitney test) plasma treatment by trend. ConclusionCold atmospheric plasma displays favourable antibacterial effects. We demonstrated that plasma treatment with the PlasmaDerm((R)) VU-2010 device is safe and effective in patients with chronic venous leg ulcers. Thus, larger controlled trials and the development of devices with larger application surfaces are warranted."],["dc.identifier.doi","10.1111/jdv.12490"],["dc.identifier.isi","000346733800024"],["dc.identifier.pmid","24666170"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38612"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1468-3083"],["dc.relation.issn","0926-9959"],["dc.title","Alleviation of chronic venous leg ulcers with a hand-held dielectric barrier discharge plasma generator (PlasmaDerm (R) VU-2010): results of a monocentric, two-armed, open, prospective, randomized and controlled trial (NCT01415622)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","140"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","141"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Mograby, Nerjes"],["dc.contributor.author","Ngassa, A."],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, M."],["dc.contributor.author","Rosenberger, Albert"],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.date.accessioned","2018-11-07T09:58:44Z"],["dc.date.available","2018-11-07T09:58:44Z"],["dc.date.issued","2015"],["dc.identifier.isi","000360219000395"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37429"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Primary Melanoma in Association with pre Navi: Results of a prospective Observational Study involving 832 High Risk Patients"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Groenemeyer, L.-L."],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Zutt, Markus"],["dc.contributor.author","von Fintel, H."],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Thoms, Kai Martin"],["dc.date.accessioned","2018-11-07T09:58:42Z"],["dc.date.available","2018-11-07T09:58:42Z"],["dc.date.issued","2015"],["dc.format.extent","97"],["dc.identifier.isi","000360219000277"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37426"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Nd:YAG- and pulsed Colouring Laster-Therapy of 271 infantile Haemangiomas in 149 Children: a retrospective Analysis"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","432"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","434"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Wolff, Cornelia R."],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Hofmann, Lars"],["dc.contributor.author","Brauns, Birka"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.date.accessioned","2018-11-07T09:40:40Z"],["dc.date.available","2018-11-07T09:40:40Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1111/ddg.12281"],["dc.identifier.isi","000335569700013"],["dc.identifier.pmid","24533883"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33555"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Rapidly growing blue-red nodule on the cheek of a 4-year-old boy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1183"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","ARCHIVES OF DERMATOLOGY"],["dc.bibliographiccitation.lastpage","1185"],["dc.bibliographiccitation.volume","148"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Kraus, Sophie Luise"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Kretschmer, Lutz"],["dc.contributor.author","Voelker, Bernward"],["dc.contributor.author","Asper, Hiba"],["dc.contributor.author","Kapp, Alexander"],["dc.contributor.author","Gutzmer, Ralf"],["dc.date.accessioned","2018-11-07T09:05:05Z"],["dc.date.available","2018-11-07T09:05:05Z"],["dc.date.issued","2012"],["dc.description.abstract","Background: Therapy with vemurafenib, an inhibitor of mutated BRAF, yields a response rate of approximately 50% in patients with metastatic melanoma harboring a BRAF V600E mutation. As an adverse effect of vemurafenib, proliferative disorders of keratinocytes, including squamous cell carcinoma, have been described. Low concentration of vemurafenib as present in the epidermis were found to activate wild-type RAF, which, in combination with a preexisting RAS mutation, can promote keratinocyte proliferation. While activating BRAF mutations occur in approximately 50% of melanomas, they are even more frequently observed in melanocytic nevi. Observation: We present the case of a patient with dynamic changes of melanocytic nevi well documented by sequential digital dermoscopy during vemurafenib therapy. A variety of dermoscopic changes were observed. First, nevi involuted, and all of these originally showed a centrally elevated papillomatous and predominant globular pattern. Second, preexisting nevi increased in size, and pigmentation that rendered them atypical. Such lesions were flat and showed a predominant reticular pattern at baseline. Third, multiple new nevi occurred. One example of each of the latter 2 categories was excised and showed wild-type BRAF. Conclusion: Our findings of changing nevi in a patient treated with vemurafenib highlight the need for sequential skin examinations, including dermoscopy. Arch Dermatol. 2012;148(10):1183-1185. Published online August 20, 2012. doi:10.1001/archdermato1.2012.2649"],["dc.identifier.doi","10.1001/archdermatol.2012.2649"],["dc.identifier.isi","000309900300014"],["dc.identifier.pmid","22911096"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25244"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0003-987X"],["dc.title","Dynamic Changes in Nevi of a Patient With Melanoma Treated With Vemurafenib Importance of Sequential Dermoscopy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","362"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","364"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Wolff, Cornelia R."],["dc.contributor.author","Hofmann, Lars"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.date.accessioned","2018-11-07T09:42:03Z"],["dc.date.available","2018-11-07T09:42:03Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1111/ddg.12235"],["dc.identifier.isi","000333701400013"],["dc.identifier.pmid","24698594"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33870"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Grouped vesicles with brown background pigmentation on the abdomen of a 9-year-old girl"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","931"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Clinical and Experimental Dermatology"],["dc.bibliographiccitation.lastpage","932"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Seitz, Cornelia S."],["dc.contributor.author","Schwarz, A."],["dc.contributor.author","Engelke, C."],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T09:16:46Z"],["dc.date.available","2018-11-07T09:16:46Z"],["dc.date.issued","2013"],["dc.identifier.doi","10.1111/ced.12145"],["dc.identifier.isi","000330244200024"],["dc.identifier.pmid","23659786"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28007"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1365-2230"],["dc.relation.issn","0307-6938"],["dc.title","Dermatological features identifying a new family with the cancer-prone Birt-Hogg-Dube syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]