Nauck, Friedemann

[["dc.bibliographiccitation.firstpage","43"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Supportive Care in Cancer"],["dc.bibliographiccitation.lastpage","49"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Stiel, Stephanie"],["dc.contributor.author","Bertram, L."],["dc.contributor.author","Neuhaus, S."],["dc.contributor.author","Nauck, F."],["dc.contributor.author","Ostgathe, Christoph"],["dc.contributor.author","Elsner, Frank"],["dc.contributor.author","Radbruch, Lukas"],["dc.date.accessioned","2018-11-07T08:48:37Z"],["dc.date.available","2018-11-07T08:48:37Z"],["dc.date.issued","2010"],["dc.description.abstract","Most terminally ill patients request information about their remaining life span. Professionals are not generally willing to provide prognosis on survival, even though they are expected to be able to do so from their clinical experience. This study aims to find out whether the standardized instruments Palliative Prognostic Index (PPI) and the Palliative Prognostic Score (PaP-S) are appropriate, specific, and sensitive to estimate survival time in patients receiving inpatient palliative care in Germany. PPI and PaP-S were assessed in addition to the core documentation data set of the Hospice and Palliative Care Evaluation for patients admitted to the palliative care units in Aachen, Bonn, and Cologne. Time of survival was assessed with repeated phone calls to the family and was defined as the difference between the day of completion of the instruments (excluded) and the day of death (included). Survival time was compared with physicians' estimations and prognostic scores in 83 patients. Whereas the estimates of the PPI and the PaP-S correlate highly, even higher correlations are found for the physicians' prognosis and the scores. Correlations between survival time and the prognostic scores or physicians' prognosis were lower. Physicians' estimations overestimated survival time on average fourfold. Estimations were more often correct for very good and very bad prognosis. The prognostic scores are not able to produce a precise reliable prognosis for the individual patient. Nevertheless, they can be used for ethical decision making and team discussions. Estimating survival time from clinical experience seems to be easier for very bad or very good prognosis for physicians."],["dc.identifier.doi","10.1007/s00520-009-0628-0"],["dc.identifier.isi","000271963100006"],["dc.identifier.pmid","19381693"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6758"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21260"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0941-4355"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Evaluation and comparison of two prognostic scores and the physicians' estimate of survival in terminally ill patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","771"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Supportive Care in Cancer"],["dc.bibliographiccitation.lastpage","777"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Voltz, Raymond"],["dc.contributor.author","Galushko, Maren"],["dc.contributor.author","Walisko, Johanna"],["dc.contributor.author","Karbach, Ute"],["dc.contributor.author","Ernstmann, Nicole"],["dc.contributor.author","Pfaff, Holger"],["dc.contributor.author","Nauck, Friedemann"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Ostgathe, Christoph"],["dc.date.accessioned","2018-11-07T08:55:56Z"],["dc.date.available","2018-11-07T08:55:56Z"],["dc.date.issued","2011"],["dc.description.abstract","Purpose To be able to study the desire for hastened death (DhD) in patients receiving palliative care, research tools reflecting the thoughts of patients are needed. In order to better understand what issues of \"life\" and \"death\" mean to patients receiving palliative care in Germany, we analysed their spontaneous comments during a validation study of the German version of the Schedule of Attitudes Towards Hastened Death. Method Field notes and transcripts of 39 interviews were analysed by thematic analysis. Method Field notes from 32 patients were related to differentiating either an acute or a non-acute DhD. Furthermore, the patients' comments were categorized and the distribution of codes analysed, leading to three types of comments: (a) longing for life excluding a hastened death, (b) wanting to live on, but perceiving death as an option, and (c) longing for death, but struggling for life. Conclusion The existing construct of an increased DhD may benefit from a further differentiation between \"non-acute\" and \"acute.\" In addition, it could be helpful to conceptualize \"will to live\" and \"desire for death\" not as polarities from one dimension (two sides of the same coin), but to think them as two independent dimensions."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft DFG [Vo 497/4-1]"],["dc.identifier.doi","10.1007/s00520-010-0876-z"],["dc.identifier.isi","000290029700007"],["dc.identifier.pmid","20422231"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23027"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0941-4355"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Issues of \"life\" and \"death\" for patients receiving palliative care-comments when confronted with a research tool"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","605"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Der Schmerz"],["dc.bibliographiccitation.lastpage","612"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Bertram, L."],["dc.contributor.author","Stiel, Stephanie"],["dc.contributor.author","Elsner, Frank"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Davies, A."],["dc.contributor.author","Nauck, F."],["dc.contributor.author","Alt-Epping, Bernd"],["dc.date.accessioned","2018-11-07T08:36:33Z"],["dc.date.available","2018-11-07T08:36:33Z"],["dc.date.issued","2010"],["dc.description.abstract","Of cancer patients receiving palliative care, 80% suffer from cancer pain, and again 80% of these patients report breakthrough pain. This study explores the patients' perception of breakthrough pain, their experiences with existing therapeutic regimens and their expectations regarding an ideal breakthrough pain medication. From November 2008 to February 2010 two German palliative care units recruited 80 in- or outpatient cancer patients who completed a standardized questionnaire on breakthrough pain characteristics, analgesic medication, attitudes towards new treatment approaches for breakthrough pain, and experiences with alternative routes of drug administration as part of the \"European Survey of Oncology Patients' Experience of Breakthrough Pain\". The study participants suffered from 1-12 episodes of either incident (47.5%) or spontaneous pain (37.5%) per day which were perceived as \"severe\" in 71% of all cases. These exacerbations highly interfered with the patients' general activity, mood, walking ability, and normal work. Overall, 64% of the patients reported alleviation from pharmacological (26%) and non-pharmacological (73%) interventions. Subcutaneous (40%) and oral (39%) routes were used frequently; intranasal (1.25%) and intrapulmonary (1.25%) routes were used rarely. Only 64% of all participants stated an overall satisfaction with their breakthrough analgesia. The diagnosis and treatment of breakthrough pain seems to be conducted in a suboptimal manner, and standard recommendations on breakthrough pain relief are not implemented consistently. Possible causes of pain should be taken into account as well as multi-professional treatment interventions and alternative routes of administration of fast onset, effective drugs should be considered."],["dc.identifier.doi","10.1007/s00482-010-0989-9"],["dc.identifier.isi","000284958500007"],["dc.identifier.pmid","21046170"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6207"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18340"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0932-433X"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights","CC BY-NC 2.0"],["dc.title","Experiences of cancer patients with breakthrough pain and pharmacological treatments"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1157"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Supportive Care in Cancer"],["dc.bibliographiccitation.lastpage","1163"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Ostgathe, Christoph"],["dc.contributor.author","Gaertner, Jan"],["dc.contributor.author","Kotterba, Maren"],["dc.contributor.author","Klein, Sebastian"],["dc.contributor.author","Lindena, Gabriele"],["dc.contributor.author","Nauck, Friedemann"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Voltz, Raymond"],["dc.date.accessioned","2018-11-07T08:40:13Z"],["dc.date.available","2018-11-07T08:40:13Z"],["dc.date.issued","2010"],["dc.description.abstract","Cancer may affect the central nervous system either by primary or secondary brain tumours (PBT/SBT). Specific needs of these patients and special requirements of services caring for them have not been adequately addressed so far. Since 1999, an annual, 3-month census is being conducted in different palliative care settings throughout Germany. Pooled data from the years 2002-2005 were analysed to test for differences between patients with PBT, SBT and other palliative care patients (OP). Symptom frequencies, ECOG status and nursing needs were tested for differences (chi A(2)). Free text entries for reasons for admission were recorded, categorised and analysed descriptively. A total of 5,684 patients were documented (PBT n = 153, 2.7%; SBT n = 661, 11.9%; OP n = 4,872, 85.4%). For patients with PBT, poor functional status and high need for nursing support was reported more frequently than for patients with SBT and OP. For patients with PBT/SBT physical symptoms (pain, nausea, vomiting, constipation and loss of appetite) were documented less frequently and in lower intensity than for OP. However, nursing, psychological, and social problems/symptoms were documented significantly more often and showed higher intensity, particularly the patients' need for support with the activities of daily living, disorientation/confusion of the patients and overburdening of the family. For 67% of all patients, a reason for admission was documented in free text. Main reasons were symptom control (OP > SBT > PBT), social issues (PBT > SBT > OP), functional deficits (PBT > SBT > OP) and cognitive impairment (PBT/SBT > OP). Distinct neurological deficits and problems were documented more often as secondary ICD-diagnoses than as a leading reason for admission. The specific palliative care problems and the rationales leading to health care utilisation point to the need for an appropriate interdisciplinary and multi-professional provision of care for patients with brain malignancies, with a particular view on the needs of the families and an early integration of social and psychological support."],["dc.identifier.doi","10.1007/s00520-009-0735-y"],["dc.identifier.isi","000280405800006"],["dc.identifier.pmid","19763633"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6760"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19174"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0941-4355"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Differential palliative care issues in patients with primary and secondary brain tumours"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","325"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Supportive Care in Cancer"],["dc.bibliographiccitation.lastpage","333"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Stiel, Stephanie"],["dc.contributor.author","Krumm, Norbert"],["dc.contributor.author","Pestinger, Martina"],["dc.contributor.author","Lindena, Gabriele"],["dc.contributor.author","Nauck, Friedemann"],["dc.contributor.author","Ostgathe, Christoph"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Elsner, Frank"],["dc.date.accessioned","2018-11-07T09:14:10Z"],["dc.date.available","2018-11-07T09:14:10Z"],["dc.date.issued","2012"],["dc.description.abstract","Patients with advanced cancer are highly susceptible to infections. The decision whether to treat an active or suspected infection or to withhold or withdraw an antibiotic treatment in end-of-life care may be difficult. In order to quantify the antimicrobial prescribing practices and decision-making processes in palliative care units in Germany, a survey was performed as part of the Hospice and Palliative Evaluation in 2006. With a specifically designed questionnaire, 448 patients for whom an active or suspected infection and antibiotic treatment was discussed were documented. Data on the use of and indication for antibiotic treatment and the decision-making on withdrawal or withholding of antibiotic therapy were collected. 286 (63.8%) received an antibiotic therapy. In 88 cases, withdrawal of an ongoing treatment was documented. The most frequent reasons for withdrawal were: deterioration of general status (41.4%), inefficiency of therapy (25.7%), and explicit wish of patient (14.3%; multiple answers possible). Outcome of antimicrobial therapy was rated poor or very poor for a fifth of the cases and accordingly, antibiotics were more likely to be withdrawn if the clinical success was considered to be poor. The initiation of therapy was often decided by physicians solely, whereas withdrawing and withholding therapy demanded more often involvement of other team members in the decision-making process. The initiation of therapy seems to be easier than withdrawing and withholding, as involvement of other team members in the decision-making process was then sought more often. When antibiotics were given until death, the indication should be reconsidered because of a possibly undesirable prolongation of the dying process. Clinical practice may benefit from clear definitions of treatment goals and outcome criteria to better evaluate the necessity for and success of antimicrobial treatment."],["dc.identifier.doi","10.1007/s00520-011-1084-1"],["dc.identifier.isi","000298356500014"],["dc.identifier.pmid","21274577"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27343"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0941-4355"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Antibiotics in palliative medicine-results from a prospective epidemiological investigation from the HOPE survey"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","859"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Supportive Care in Cancer"],["dc.bibliographiccitation.lastpage","868"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Pastrana, Tania"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Nauck, Friedemann"],["dc.contributor.author","Hoever, Gerhard"],["dc.contributor.author","Fegg, Martin"],["dc.contributor.author","Pestinger, Martina"],["dc.contributor.author","Ross, Josef"],["dc.contributor.author","Krumm, Norbert"],["dc.contributor.author","Ostgathe, Christoph"],["dc.date.accessioned","2018-11-07T08:42:03Z"],["dc.date.available","2018-11-07T08:42:03Z"],["dc.date.issued","2010"],["dc.description.abstract","The call for clinically relevant outcome criteria has been raised, as assessment of adequate quality of service providers is essential with increasing momentum in the development of palliative care in most European countries. The aim of this study is to investigate important dimensions and indicators for assessment and evaluation of palliative care from the perspective of multi-disciplinary German experts working over years in the field of palliative care. A focus group, using the structured consensus method of the improved nominal group technique (INGT), with nine experts from different disciplines was conducted in Germany. An abundance of topics (16) were identified, pointing at the complexity of the issue. Main topics were: quality of life, needs assessments of patients and relatives, resource assessment, surveillance of decision-making processes, as well as spiritual well-being. The following properties were claimed as essential for outcome criteria sensitivity, without additional burden on patients, easy applicability, scientific validity, and helpful for communication within the team, ethical discussions as well as for quality management. The study identified topics considered important by experts in clinical practise. The discussions exposed the diversity of demands on outcome assessment put up by different stakeholder groups. This and the high number of relevant items show the complexity for the agreement on a unique set of outcome criteria. Further research considering other perspectives is needed."],["dc.description.sponsorship","Deutsche Krebshilfe (German Cancer Aid) [107509]"],["dc.identifier.doi","10.1007/s00520-009-0721-4"],["dc.identifier.isi","000277943300008"],["dc.identifier.pmid","19701782"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6759"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19616"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0941-4355"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Outcome indicators in palliative care-how to assess quality and success. Focus group and nominal group technique in Germany"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","52"],["dc.bibliographiccitation.journal","BMC Medical Ethics"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Nauck, Friedemann"],["dc.contributor.author","Becker, Matthias"],["dc.contributor.author","King, Claudius"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Voltz, Raymond"],["dc.contributor.author","Jaspers, Birgit"],["dc.date.accessioned","2018-11-07T09:38:44Z"],["dc.date.available","2018-11-07T09:38:44Z"],["dc.date.issued","2014"],["dc.description.abstract","Background: Advance directives (ADs) are assumed to reflect the patients' preferences, even if these are not clearly expressed. Research into whether this assumption is correct has been lacking. This study explores to what extent ADs reflect the true wishes of the signatories. Methods: Semi-structured interviews (INT), pretest. Transcribed INT and the contents of ADs were inductively categorised (Mayring) and triangulated. Software: MAXQDA 2007. Participants: Patients receiving palliative care (PPC), healthy (H) and chronically ill (CI) individuals with an AD completed >= 3 months prior to recruitment. Results: Between 08/2008 and 07/2009, 53 individuals (20 H, 17 CI, 16 PPC) were interviewed (mean age 63.2 years (55-70 years)), 34% male). Most important (in) consistencies between preferences as expressed in INT compared to ADs included preconditions for termination/rejection of life-sustaining measures, refusal of/demand for medical interventions and the nomination of proxies. Standardized AD forms were rarely tailored to the individual. We found a high tendency to use set phrases, such as want to die with dignity or do not want to suffer/vegetate. Likely events in the course of an existing progressive disease were not covered, even in ADs of PPC close to death. Conclusions: Only some of the incongruities between verbally expressed preferences and the contents of the AD can be put down to use of standardized forms or lack of medical knowledge. Nevertheless, the non-involvement of a doctor in the process of making an AD must be seen as potentially problematic and seeking medical advice should be promoted by politics and physicians. Standardised forms should encourage amendments and present space for free text entries for all aspects covered. Set phrases need to be defined by the individual to enable them to be translated into a specific course of action."],["dc.description.sponsorship","German Research Foundation [NA 780/1-1]"],["dc.identifier.doi","10.1186/1472-6939-15-52"],["dc.identifier.isi","000338570000001"],["dc.identifier.pmid","24981101"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10432"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33129"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1472-6939"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","To what extent are the wishes of a signatory reflected in their advance directive: a qualitative analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","751"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Palliative Medicine"],["dc.bibliographiccitation.lastpage","752"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Nauck, Friedemann"],["dc.date.accessioned","2018-11-07T08:36:29Z"],["dc.date.available","2018-11-07T08:36:29Z"],["dc.date.issued","2010"],["dc.identifier.doi","10.1177/0269216310388070"],["dc.identifier.isi","000285049900001"],["dc.identifier.pmid","21139046"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8356"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18322"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.relation.issn","0269-2163"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","How should I know? Researching attitudes and practices around hastening death"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]