Now showing 1 - 6 of 6
  • 2015Conference Abstract
    [["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Baltzer, Anne"],["dc.contributor.author","Forkel, Susann"],["dc.contributor.author","Al Ghazal, Philipp"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Thoms, Kai Martin"],["dc.contributor.author","Kretschmer, Lutz"],["dc.date.accessioned","2018-11-07T09:53:40Z"],["dc.date.available","2018-11-07T09:53:40Z"],["dc.date.issued","2015"],["dc.format.extent","41"],["dc.identifier.isi","000360219800091"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36374"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Complete Remission of cutaneous Melanoma Metastases with Combination Therapy of Ipilimumab and Diphenylcyclopropenone (DPCP)"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.firstpage","158"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Melanoma Research"],["dc.bibliographiccitation.lastpage","164"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Al Ghazal, Philipp"],["dc.contributor.author","Gutzmer, Ralf"],["dc.contributor.author","Satzger, Imke"],["dc.contributor.author","Starz, Hans"],["dc.contributor.author","Bader, Christina"],["dc.contributor.author","Thoms, Kai-Martin"],["dc.contributor.author","Mitteldorf, Christina"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Kapp, Alexander"],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.contributor.author","Kretschmer, Lutz"],["dc.date.accessioned","2018-11-07T09:42:15Z"],["dc.date.available","2018-11-07T09:42:15Z"],["dc.date.issued","2014"],["dc.description.abstract","Head or neck location of primary cutaneous melanomas has been described as an adverse prognostic factor, but this has to be reassessed after the introduction of sentinel lymph node (SLN) excision (SLNE). Descriptive statistics, Kaplan-Meier estimates and Cox proportional hazard models were used to study retrospectively a population of 2302 consecutive melanoma patients from three German melanoma centres undergoing SLNE. Approximately 10% of the patients (N=237) had a primary melanoma located at the head or neck (HNM). In both the SLN-positive and SLN-negative subpopulation, patients with HNM were significantly older, more frequently men and had thicker primaries compared with patients with tumours in other locations. The proportion of positive SLNs was lower in HNM compared with other locations of the primary (20 vs. 26%, P=0.048). The false-negative rate was higher in HNM (17.5 vs. 8.4%, P=0.05). In patients with HNM, the SLN status was a significant factor for recurrence-free survival but not for overall survival. SLN-negative HNM patients had a significantly worse overall survival than the SLN negatives with primaries at other sites, whereas the prognosis of the SLN-positive patients was similar in both groups. The prevalence of lymph node metastases after SLNE is lower in patients with HNM compared with other melanoma locations. As a result, the prognostic information provided by the SLN for HNM seems less important. Decision making for SLNE in HNM should be carefully balanced considering the potential morbidity of the procedure."],["dc.identifier.doi","10.1097/CMR.0000000000000042"],["dc.identifier.isi","000332601400009"],["dc.identifier.pmid","24346168"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33915"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","1473-5636"],["dc.relation.issn","0960-8931"],["dc.title","Lower prevalence of lymphatic metastasis and poorer survival of the sentinel node-negative patients limit the prognostic value of sentinel node biopsy for head or neck melanomas"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2015Conference Abstract
    [["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Kretschmer, Lutz"],["dc.contributor.author","Hellriegel, Simin"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Baltzer, Anne"],["dc.contributor.author","Al Ghazal, Philipp"],["dc.contributor.author","Thoms, Kai Martin"],["dc.date.accessioned","2018-11-07T09:53:40Z"],["dc.date.available","2018-11-07T09:53:40Z"],["dc.date.issued","2015"],["dc.format.extent","13"],["dc.identifier.isi","000360219800034"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36372"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Factors with Influence on the Amount of Fuid Drainage after radical Lymphadenectomy in Melanoma"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","120"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Lymphology"],["dc.bibliographiccitation.lastpage","130"],["dc.bibliographiccitation.volume","50"],["dc.contributor.author","Kretschmer, L."],["dc.contributor.author","Hellriegel, S."],["dc.contributor.author","Thoms, K. M."],["dc.contributor.author","Schon, M. P."],["dc.contributor.author","Al Ghazal, P."],["dc.contributor.author","Zapf, A."],["dc.date.accessioned","2019-01-29T10:49:53Z"],["dc.date.available","2019-01-29T10:49:53Z"],["dc.date.issued","2017"],["dc.description.abstract","Lymphedema (LE) following lymph node dissection is a major problem for cancer patients, and radiation therapy, extended surgery, groin dissection, obesity, and older age are well-established risk factors of LE. We studied whether these risk factors are further associated with high volumes of postoperative drainage fluid after complete lymph node dissection (CLND) for melanoma metastases. Moreover, we examined whether a high amount of drainage fluid after sentinel lymph node biopsy (SLNB) can predict a high amount of drainage fluid after subsequent CLND. Using descriptive statistics and regression analyses, we analyzed the cumulative volumes of postoperative drainage fluid for 836 melanoma patients with lymph node excision in the axilla or groin. In multiple regression analyses, the well-established risk factors of LE, i.e., increased body mass index, older age, and ilioinguinal versus inguinal versus axillary dissection predicted a high drainage volume after CLND. Of note, a high drainage fluid volume after SLNB also predicted a high drainage volume after subsequent CLND. In patients with groin dissections, who are particularly susceptible to swelling, extended iliac dissection, age above 60, and a cumulative drainage volume of more than 100 ml in the preceding SLNB were predictors of the cumulative drainage volume. We find that common risk factors predict the volume of postoperative drainage fluid after CLND and postoperative LE. Further, high postoperative drainage volume may therefore function as a potential early predictor of LE following CLND."],["dc.identifier.pmid","30234248"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/57419"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","2522-7963"],["dc.title","The volume of postoperative drainage fluid as a potential early predictor of lymphedema after lymph node excision for metastatic melanoma"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2016Conference Abstract
    [["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Bremmer, S."],["dc.contributor.author","Amschler, Katharina"],["dc.contributor.author","Al Ghazal, Philipp"],["dc.contributor.author","Olbricht, N."],["dc.contributor.author","Schon, M."],["dc.contributor.author","Kretschmer, Lutz"],["dc.contributor.author","Thoms, Kai Martin"],["dc.date.accessioned","2018-11-07T10:08:54Z"],["dc.date.available","2018-11-07T10:08:54Z"],["dc.date.issued","2016"],["dc.format.extent","40"],["dc.identifier.isi","000383669600091"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39560"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Remission of metastatic Melanomas under Checkpoint Inhibition does not protect against the bright Skin Cancer"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2012Conference Abstract
    [["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Al Ghazal, Philipp"],["dc.contributor.author","Gutzmer, Ralf"],["dc.contributor.author","Satzger, Imke"],["dc.contributor.author","Starz, Hans"],["dc.contributor.author","Thoms, Kai Martin"],["dc.contributor.author","Jung, Klaus"],["dc.contributor.author","Mitteldorf, Christina"],["dc.contributor.author","Bader, Claudia"],["dc.contributor.author","Kapp, Alexander"],["dc.contributor.author","Bertsch, Hans Peter"],["dc.contributor.author","Kretschmer, Lutz"],["dc.date.accessioned","2018-11-07T09:06:47Z"],["dc.date.available","2018-11-07T09:06:47Z"],["dc.date.issued","2012"],["dc.format.extent","691"],["dc.identifier.isi","000307881400077"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25631"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0379"],["dc.title","Prognostic value of SLN biopsy of the head/neck in comparison to trunk and extremities in cutaneous melanomas"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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